3l7r - Revision history

OCA at 16:21, 1 November 2023

OCA — Wed, 01 Nov 2023 16:21:35 GMT

←Older revision		Revision as of 16:21, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3l7r' size='340' side='right'caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='3l7r' size='340' side='right'caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Strmu Strmu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7R FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.397Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3l7s\|3l7s]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>SMU_873 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~210007 STRMU])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[https://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [https://pdbe.org/3l7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [https://www.ebi.ac.uk/pdbsum/3l7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7r ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [https://pdbe.org/3l7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [https://www.ebi.ac.uk/pdbsum/3l7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).	+	[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3l7r" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3l7r" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Methionine synthase 3D structures\|Methionine synthase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Strmu~~]]	+	[[Category: Streptococcus mutans UA159]]
-	[[Category: Fu~~, T M~~]]	+	[[Category: Fu TM]]
-	[[Category: Liang~~, Y H~~]]	+	[[Category: Liang YH]]
-	[[Category: Su~~, X D]]~~	+	[[Category: Su XD]]
-	~~[[Category: Amino-acid biosynthesis]]~~	+
-	~~[[Category: Cobalamin]]~~	+
-	~~[[Category: Mete]]~~	+
-	~~[[Category: Methionine biosynthesis]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Streptococcus mutan]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 13:37, 4 May 2022

OCA — Wed, 04 May 2022 13:37:50 GMT

←Older revision		Revision as of 13:37, 4 May 2022
Line 1:		Line 1:

	==crystal structure of MetE from streptococcus mutans==		==crystal structure of MetE from streptococcus mutans==
-	<StructureSection load='3l7r' size='340' side='right' caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='3l7r' size='340' side='right'caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Strmu Strmu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3L7R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Strmu Strmu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L7R FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3l7s\|3l7s]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210007 STRMU])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210007 STRMU])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [~~http~~://pdbe.org/3l7r PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3l7r PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7r ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [https://pdbe.org/3l7r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [https://www.ebi.ac.uk/pdbsum/3l7r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).	+	[[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
		+	[[Category: Large Structures]]
	[[Category: Strmu]]		[[Category: Strmu]]
	[[Category: Fu, T M]]		[[Category: Fu, T M]]

OCA at 14:41, 5 August 2016

OCA — Fri, 05 Aug 2016 14:41:57 GMT

←Older revision		Revision as of 14:41, 5 August 2016
Line 1:		Line 1:
		+
	==crystal structure of MetE from streptococcus mutans==		==crystal structure of MetE from streptococcus mutans==
	<StructureSection load='3l7r' size='340' side='right' caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='3l7r' size='340' side='right' caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_mutans Streptococcus mutans~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7R FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strmu Strmu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7R FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1309 Streptococcus mutans~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210007 STRMU])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [http://www.ebi.ac.uk/pdbsum/3l7r PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [http://pdbe.org/3l7r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [http://www.ebi.ac.uk/pdbsum/3l7r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l7r ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3l7r" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
-	[[Category: ~~Streptococcus mutans~~]]	+	[[Category: Strmu]]
	[[Category: Fu, T M]]		[[Category: Fu, T M]]
	[[Category: Liang, Y H]]		[[Category: Liang, Y H]]

OCA at 19:39, 25 December 2014

OCA — Thu, 25 Dec 2014 19:39:37 GMT

←Older revision		Revision as of 19:39, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7R FirstGlance]. <br>		<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7R FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [http://www.ebi.ac.uk/pdbsum/3l7r PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [http://www.ebi.ac.uk/pdbsum/3l7r PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 17:
	Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>		Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 23:		Line 25:
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]
-	[[Category: Fu, T M.]]	+	[[Category: Fu, T M]]
-	[[Category: Liang, Y H.]]	+	[[Category: Liang, Y H]]
-	[[Category: Su, X D.]]	+	[[Category: Su, X D]]
	[[Category: Amino-acid biosynthesis]]		[[Category: Amino-acid biosynthesis]]
	[[Category: Cobalamin]]		[[Category: Cobalamin]]

OCA at 09:48, 21 May 2014

OCA — Wed, 21 May 2014 09:48:08 GMT

←Older revision		Revision as of 09:48, 21 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3l7r.~~png~~\|~~left~~\|~~200px~~]]	+	==crystal structure of MetE from streptococcus mutans==
		+	<StructureSection load='3l7r' size='340' side='right' caption='[[3l7r]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L7R FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7s\|3l7s]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SMU_873 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l7r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l7r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l7r RCSB], [http://www.ebi.ac.uk/pdbsum/3l7r PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cobalamin-independent methionine synthase (MetE) catalyzes the direct transfer of a methyl group from methyltetrahydrofolate to l-homocysteine to form methionine. Previous studies have shown that the MetE active site coordinates a zinc atom, which is thought to act as a Lewis acid and plays a role in the activation of thiol. Extended X-ray absorption fine structure studies and mutagenesis experiments identified the zinc-binding site in MetE from Escherichia coli. Further structural investigations of MetE from Thermotoga maritima lead to the proposition of two models: "induced fit" and "dynamic equilibrium", to account for the catalytic mechanisms of MetE. Here, we present crystal structures of oxidized and zinc-replete MetE from Streptococcus mutans at the physiological pH. The structures reveal that zinc is mobile in the active center and has the possibility to invert even in the absence of homocysteine. These structures provide evidence for the dynamic equilibrium model.

-	<!--	+	Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3l7r"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3l7r\| PDB=3l7r \| SCENE= }}~~	+

-	~~===crystal structure~~ of ~~MetE from streptococcus mutans===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21840320}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21840320 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21840320}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3l7r]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021840320<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]

OCA at 04:49, 28 September 2011

OCA — Wed, 28 Sep 2011 04:49:59 GMT

←Older revision		Revision as of 04:49, 28 September 2011
Line 1:		Line 1:
-	[[Image:3l7r.~~jpg~~\|left\|200px]]	+	[[Image:3l7r.png\|left\|200px]]

	<!--		<!--
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	===crystal structure of MetE from streptococcus mutans===		===crystal structure of MetE from streptococcus mutans===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21840320}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21840320 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21840320}}

	==About this Structure==		==About this Structure==
	[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA].		[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021840320</ref><references group="xtra"/>
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]
Line 19:		Line 28:
	[[Category: Liang, Y H.]]		[[Category: Liang, Y H.]]
	[[Category: Su, X D.]]		[[Category: Su, X D.]]
		+	[[Category: Amino-acid biosynthesis]]
		+	[[Category: Cobalamin]]
		+	[[Category: Mete]]
		+	[[Category: Methionine biosynthesis]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Streptococcus mutan]]
		+	[[Category: Transferase]]

OCA: Protected "3l7r" [edit=sysop:move=sysop]

OCA — Wed, 12 Jan 2011 05:12:59 GMT

Protected "3l7r" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:12, 12 January 2011

OCA at 05:12, 12 January 2011

OCA — Wed, 12 Jan 2011 05:12:56 GMT

←Older revision		Revision as of 05:12, 12 January 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3l7r.jpg\|left\|200px]]

-	The ~~entry 3l7r~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3l7r", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3l7r\| PDB=3l7r \| SCENE= }}

-	~~Authors: Fu, T.M., Liang, Y.H., Su, X.D.~~	+	===crystal structure of MetE from streptococcus mutans===

-	Description: crystal structure of MetE from streptococcus mutans

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Jan 27 19~~:16:~~20 2010''~~	+	==About this Structure==
		+	[[3l7r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L7R OCA].
		+	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
		+	[[Category: Streptococcus mutans]]
		+	[[Category: Fu, T M.]]
		+	[[Category: Liang, Y H.]]
		+	[[Category: Su, X D.]]

OCA at 17:16, 27 January 2010

OCA — Wed, 27 Jan 2010 17:16:21 GMT

←Older revision		Revision as of 17:16, 27 January 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3l7r is ON HOLD	+	The entry 3l7r is ON HOLD until Paper Publication

	Authors: Fu, T.M., Liang, Y.H., Su, X.D.		Authors: Fu, T.M., Liang, Y.H., Su, X.D.
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	Description: crystal structure of MetE from streptococcus mutans		Description: crystal structure of MetE from streptococcus mutans

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan ~~6 09~~:14:36 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 27 19:16:20 2010''

OCA: New page: '''Unreleased structure''' The entry 3l7r is ON HOLD Authors: Fu, T.M., Liang, Y.H., Su, X.D. Description: crystal structure of MetE from streptococcus mutans ''Page seeded by [http:/...

OCA — Wed, 06 Jan 2010 07:14:36 GMT

New page: '''Unreleased structure''' The entry 3l7r is ON HOLD Authors: Fu, T.M., Liang, Y.H., Su, X.D. Description: crystal structure of MetE from streptococcus mutans ''Page seeded by [http:/...

New page

'''Unreleased structure'''

The entry 3l7r is ON HOLD

Authors: Fu, T.M., Liang, Y.H., Su, X.D.

Description: crystal structure of MetE from streptococcus mutans

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 09:14:36 2010''