3l82 - Revision history

OCA at 06:53, 2 January 2019

OCA — Wed, 02 Jan 2019 06:53:02 GMT

←Older revision		Revision as of 06:53, 2 January 2019
Line 1:		Line 1:
		+
	==X-ray Crystal structure of TRF1 and Fbx4 complex==		==X-ray Crystal structure of TRF1 and Fbx4 complex==
	<StructureSection load='3l82' size='340' side='right' caption='[[3l82]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='3l82' size='340' side='right' caption='[[3l82]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TERF1, PIN2, TRBF1, TRF, TRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), FBXO4, FBX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TERF1, PIN2, TRBF1, TRF, TRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), FBXO4, FBX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://pdbe.org/3l82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://pdbe.org/3l82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3l82 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l82_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l82_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 14:51, 8 February 2016

OCA — Mon, 08 Feb 2016 14:51:02 GMT

←Older revision		Revision as of 14:51, 8 February 2016
Line 2:		Line 2:
	<StructureSection load='3l82' size='340' side='right' caption='[[3l82]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='3l82' size='340' side='right' caption='[[3l82]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3l82]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L82 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3l82]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L82 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TERF1, PIN2, TRBF1, TRF, TRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~]), FBXO4, FBX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TERF1, PIN2, TRBF1, TRF, TRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), FBXO4, FBX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://pdbe.org/3l82 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l82 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3l82" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Chen, Y]]		[[Category: Chen, Y]]
	[[Category: Diehl, J A]]		[[Category: Diehl, J A]]

OCA at 00:08, 25 December 2014

OCA — Thu, 25 Dec 2014 00:08:56 GMT

←Older revision		Revision as of 00:08, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TERF1_HUMAN TERF1_HUMAN]] Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.<ref>PMID:16166375</ref> [[http://www.uniprot.org/uniprot/FBX4_HUMAN FBX4_HUMAN]] Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.<ref>PMID:10531035</ref> <ref>PMID:16275645</ref> <ref>PMID:18598945</ref> <ref>PMID:20159592</ref> <ref>PMID:20181953</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:38, 18 December 2014

OCA — Thu, 18 Dec 2014 17:38:53 GMT

←Older revision		Revision as of 17:38, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3l82~~\| ~~PDB~~=3l82 \| ~~SCENE~~= }}	+	==X-ray Crystal structure of TRF1 and Fbx4 complex==
-	===X-~~ray Crystal~~ structure of ~~TRF1~~ and ~~Fbx4 complex~~===	+	<StructureSection load='3l82' size='340' side='right' caption='[[3l82]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20159592}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3l82]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3L82 FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TERF1, PIN2, TRBF1, TRF, TRF1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), FBXO4, FBX4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3l82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l82 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3l82 RCSB], [http://www.ebi.ac.uk/pdbsum/3l82 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l8/3l82_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	TRF1 is a critical regulator of telomere length. As such, TRF1 levels are regulated by ubiquitin-dependent proteolysis via an SCF E3 ligase where Fbx4 contributes to substrate specification. Here, we report the crystal structure of the Fbx4-TRF1 complex at 2.4 A resolution. Fbx4 contains an unusual substrate-binding domain that adopts a small GTPase fold. Strikingly, this atypical GTPase domain of Fbx4 binds to a globular domain of TRF1 through an intermolecular beta sheet, instead of recognizing short peptides/degrons as often seen in other F-box protein-substrate complexes. Importantly, mutations in this interface abrogate Fbx4-dependent TRF1 binding and ubiquitination. Furthermore, the data demonstrate that recognition of TRF1 by SCF(Fbx4) is regulated by another telomere protein, TIN2. Our results reveal an atypical small GTPase domain within Fbx4 as a substrate-binding motif for SCF(Fbx4) and uncover a mechanism for selective ubiquitination and degradation of TRF1 in telomere homeostasis control.

-	~~==Function==~~	+	Structural basis of selective ubiquitination of TRF1 by SCFFbx4.,Zeng Z, Wang W, Yang Y, Chen Y, Yang X, Diehl JA, Liu X, Lei M Dev Cell. 2010 Feb 16;18(2):214-25. PMID:20159592<ref>PMID:20159592</ref>
-	~~[[http://www.uniprot.org/uniprot/TERF1_HUMAN TERF1_HUMAN]] Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation~~ of ~~the mitotic spindle. Component~~ of ~~the shelterin complex (telosome) that is involved in the regulation of telomere length and protection~~. ~~Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity~~, ~~telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways~~.~~<ref>PMID:16166375</ref> [[http://www.uniprot.org/uniprot/FBX4_HUMAN FBX4_HUMAN]] Substrate recognition component of a SCF~~ (~~SKP1-CUL1-F-box protein~~) ~~E3 ubiquitin~~-~~protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins~~. ~~Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.<ref>~~PMID:~~10531035</ref> <ref>PMID:16275645</ref> <ref>PMID:18598945</ref>~~ <ref>PMID:20159592</ref> ~~<ref>PMID:20181953</ref>~~	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3l82]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:020159592</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Chen, Y.]]	+	[[Category: Chen, Y]]
-	[[Category: Diehl, J A.]]	+	[[Category: Diehl, J A]]
-	[[Category: Lei, M.]]	+	[[Category: Lei, M]]
-	[[Category: Liu, X D.]]	+	[[Category: Liu, X D]]
-	[[Category: Wang, W.]]	+	[[Category: Wang, W]]
-	[[Category: Yang, X M.]]	+	[[Category: Yang, X M]]
-	[[Category: Yang, Y T.]]	+	[[Category: Yang, Y T]]
-	[[Category: Zeng, Z X.]]	+	[[Category: Zeng, Z X]]
	[[Category: Adp-ribosylation]]		[[Category: Adp-ribosylation]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]

OCA: Protected "3l82" [edit=sysop:move=sysop]

OCA — Thu, 04 Apr 2013 20:44:34 GMT

Protected "3l82" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:44, 4 April 2013

OCA at 20:44, 4 April 2013

OCA — Thu, 04 Apr 2013 20:44:26 GMT

←Older revision		Revision as of 20:44, 4 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3l82.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3l82", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3l82\| PDB=3l82 \| SCENE= }}		{{STRUCTURE_3l82\| PDB=3l82 \| SCENE= }}
-
	===X-ray Crystal structure of TRF1 and Fbx4 complex===		===X-ray Crystal structure of TRF1 and Fbx4 complex===
		+	{{ABSTRACT_PUBMED_20159592}}

-		+	==Function==
-	<!--	+	[[http://www.uniprot.org/uniprot/TERF1_HUMAN TERF1_HUMAN]] Binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.<ref>PMID:16166375</ref> [[http://www.uniprot.org/uniprot/FBX4_HUMAN FBX4_HUMAN]] Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes ubiquitination of CCND1 and its subsequent proteasomal degradation. Recognizes TERF1 and promotes its ubiquitination together with UBE2D1.<ref>PMID:10531035</ref> <ref>PMID:16275645</ref> <ref>PMID:18598945</ref> <ref>PMID:20159592</ref> <ref>PMID:20181953</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20159592}}, adds~~ the ~~Publication Abstract to~~ the ~~page~~	+
-	(~~as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~)~~, where 20159592 is~~ the ~~PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_20159592}}~~	+

	==About this Structure==		==About this Structure==
-	~~3L82~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA].	+	[[3l82]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20159592~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020159592</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Chen, Y.]]		[[Category: Chen, Y.]]
Line 33:		Line 20:
	[[Category: Yang, Y T.]]		[[Category: Yang, Y T.]]
	[[Category: Zeng, Z X.]]		[[Category: Zeng, Z X.]]
-	[[Category: Acetylation]]
	[[Category: Adp-ribosylation]]		[[Category: Adp-ribosylation]]
-	[[Category: Alternative splicing]]
	[[Category: Cell cycle]]		[[Category: Cell cycle]]
	[[Category: Cell division]]		[[Category: Cell division]]
	[[Category: Chromosomal protein]]		[[Category: Chromosomal protein]]
-	[[Category: Cytoplasm]]
	[[Category: Cytoskeleton]]		[[Category: Cytoskeleton]]
	[[Category: Dna-binding]]		[[Category: Dna-binding]]
Line 50:		Line 34:
	[[Category: Trfh domain]]		[[Category: Trfh domain]]
	[[Category: Ubl conjugation pathway]]		[[Category: Ubl conjugation pathway]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 13:46:43 2010''

OCA at 11:46, 10 March 2010

OCA — Wed, 10 Mar 2010 11:46:44 GMT

←Older revision		Revision as of 11:46, 10 March 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3l82.jpg\|left\|200px]]

-	The ~~entry 3l82~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3l82", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3l82\| PDB=3l82 \| SCENE= }}

-	~~Authors: Zeng, Z.~~X~~., Wang, W., Yang, Y.T., Chen, Y., Yang, X.M., Diehl, J.A., Liu, X.D., Lei, M.~~	+	===X-ray Crystal structure of TRF1 and Fbx4 complex===

-	Description: X-ray Crystal structure of TRF1 and Fbx4 complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 13~~ 13:34:09 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20159592}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20159592 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20159592}}
		+
		+	==About this Structure==
		+	3L82 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L82 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20159592</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Chen, Y.]]
		+	[[Category: Diehl, J A.]]
		+	[[Category: Lei, M.]]
		+	[[Category: Liu, X D.]]
		+	[[Category: Wang, W.]]
		+	[[Category: Yang, X M.]]
		+	[[Category: Yang, Y T.]]
		+	[[Category: Zeng, Z X.]]
		+	[[Category: Acetylation]]
		+	[[Category: Adp-ribosylation]]
		+	[[Category: Alternative splicing]]
		+	[[Category: Cell cycle]]
		+	[[Category: Cell division]]
		+	[[Category: Chromosomal protein]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Cytoskeleton]]
		+	[[Category: Dna-binding]]
		+	[[Category: Gtpase domain]]
		+	[[Category: Helix]]
		+	[[Category: Mitosis]]
		+	[[Category: Nucleus]]
		+	[[Category: Phosphoprotein]]
		+	[[Category: Telomere]]
		+	[[Category: Trfh domain]]
		+	[[Category: Ubl conjugation pathway]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 13:46:43 2010''

OCA at 11:34, 13 January 2010

OCA — Wed, 13 Jan 2010 11:34:09 GMT

←Older revision		Revision as of 11:34, 13 January 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3l82 is ON HOLD	+	The entry 3l82 is ON HOLD until Paper Publication

-	Authors: Zeng, ZX, Wang, W, Yang, YT, Chen, Y, Yang, XM, Diehl, JA, Liu, XD, Lei, M	+	Authors: Zeng, Z.X., Wang, W., Yang, Y.T., Chen, Y., Yang, X.M., Diehl, J.A., Liu, X.D., Lei, M.

	Description: X-ray Crystal structure of TRF1 and Fbx4 complex		Description: X-ray Crystal structure of TRF1 and Fbx4 complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan ~~6 09~~:14:43 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 13 13:34:09 2010''

OCA: New page: '''Unreleased structure''' The entry 3l82 is ON HOLD Authors: Zeng, ZX, Wang, W, Yang, YT, Chen, Y, Yang, XM, Diehl, JA, Liu, XD, Lei, M Description: X-ray Crystal structure of TRF1 an...

OCA — Wed, 06 Jan 2010 07:14:44 GMT

New page: '''Unreleased structure''' The entry 3l82 is ON HOLD Authors: Zeng, ZX, Wang, W, Yang, YT, Chen, Y, Yang, XM, Diehl, JA, Liu, XD, Lei, M Description: X-ray Crystal structure of TRF1 an...

New page

'''Unreleased structure'''

The entry 3l82 is ON HOLD

Authors: Zeng, ZX, Wang, W, Yang, YT, Chen, Y, Yang, XM, Diehl, JA, Liu, XD, Lei, M

Description: X-ray Crystal structure of TRF1 and Fbx4 complex

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 6 09:14:43 2010''