3lh2 - Revision history

OCA at 08:37, 6 September 2023

OCA — Wed, 06 Sep 2023 08:37:02 GMT

←Older revision		Revision as of 08:37, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3lh2' size='340' side='right'caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='3lh2' size='340' side='right'caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~] and [~~http~~://en.wikipedia.org/wiki/~~Synthetic_construct_sequences~~ Synthetic construct ~~sequences~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~[[3lef\|3lef]]~~, [[~~3lf6~~\|~~3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp~~]]</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.65Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [~~http~~://pdbe.org/3lh2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3lh2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3lh2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [https://pdbe.org/3lh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [https://www.ebi.ac.uk/pdbsum/3lh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lh2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Synthetic construct ~~sequences~~]]	+	[[Category: Synthetic construct]]
-	[[Category: Holmes~~, M A]]~~	+	[[Category: Holmes MA]]
-	~~[[Category: Epitope-scaffold]]~~	+
-	~~[[Category: Immune system~~]]	+

OCA at 07:06, 7 October 2020

OCA — Wed, 07 Oct 2020 07:06:55 GMT

←Older revision		Revision as of 07:06, 7 October 2020
Line 1:		Line 1:

	==Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex==		==Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex==
-	<StructureSection load='3lh2' size='340' side='right' caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>	+	<StructureSection load='3lh2' size='340' side='right'caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lef\|3lef]], [[3lf6\|3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lef\|3lef]], [[3lf6\|3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [http://pdbe.org/3lh2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lh2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lh2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [http://pdbe.org/3lh2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lh2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lh2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Synthetic construct sequences]]		[[Category: Synthetic construct sequences]]
	[[Category: Holmes, M A]]		[[Category: Holmes, M A]]
	[[Category: Epitope-scaffold]]		[[Category: Epitope-scaffold]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 06:41, 2 January 2019

OCA — Wed, 02 Jan 2019 06:41:23 GMT

←Older revision		Revision as of 06:41, 2 January 2019
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lh/3lh2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lh/3lh2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:59, 5 August 2016

OCA — Fri, 05 Aug 2016 11:59:41 GMT

←Older revision		Revision as of 11:59, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex==		==Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex==
	<StructureSection load='3lh2' size='340' side='right' caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>		<StructureSection load='3lh2' size='340' side='right' caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~] and [http://en.wikipedia.org/wiki/~~Synthetic_construct~~ Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human] and [http://en.wikipedia.org/wiki/Synthetic_construct_sequences Synthetic construct sequences]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lef\|3lef]], [[3lf6\|3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lef\|3lef]], [[3lf6\|3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lh2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [http://pdbe.org/3lh2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lh2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lh2 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 14:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lh2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3lh2" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
-	[[Category: Synthetic construct]]	+	[[Category: Synthetic construct sequences]]
	[[Category: Holmes, M A]]		[[Category: Holmes, M A]]
	[[Category: Epitope-scaffold]]		[[Category: Epitope-scaffold]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 17:29, 18 December 2014

OCA — Thu, 18 Dec 2014 17:29:52 GMT

←Older revision		Revision as of 17:29, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3lh2\| PDB=3lh2 \| SCENE= }}~~	+	==Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex==
-	===Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex===	+	<StructureSection load='3lh2' size='340' side='right' caption='[[3lh2]], [[Resolution\|resolution]] 2.65Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20826338}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LH2 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lef\|3lef]], [[3lf6\|3lf6]], [[3lf9\|3lf9]], [[3lg7\|3lg7]], [[3lhp\|3lhp]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lh2 RCSB], [http://www.ebi.ac.uk/pdbsum/3lh2 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lh/3lh2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Broadly cross-reactive monoclonal antibodies define epitopes for vaccine development against HIV and other highly mutable viruses. Crystal structures are available for several such antibody-epitope complexes, but methods are needed to translate that structural information into immunogens that re-elicit similar antibodies. We describe a general computational method to design epitope-scaffolds in which contiguous structural epitopes are transplanted to scaffold proteins for conformational stabilization and immune presentation. Epitope-scaffolds designed for the poorly immunogenic but conserved HIV epitope 4E10 exhibited high epitope structural mimicry, bound with higher affinities to monoclonal antibody (mAb) 4E10 than the cognate peptide, and inhibited HIV neutralization by HIV+ sera. Rabbit immunization with an epitope-scaffold induced antibodies with structural specificity highly similar to mAb 4E10, an important advance toward elicitation of neutralizing activity. The results demonstrate that computationally designed epitope-scaffolds are valuable as structure-specific serological reagents and as immunogens to elicit antibodies with predetermined structural specificity.

-	~~==About this Structure==~~	+	Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.,Correia BE, Ban YE, Holmes MA, Xu H, Ellingson K, Kraft Z, Carrico C, Boni E, Sather DN, Zenobia C, Burke KY, Bradley-Hewitt T, Bruhn-Johannsen JF, Kalyuzhniy O, Baker D, Strong RK, Stamatatos L, Schief WR Structure. 2010 Sep 8;18(9):1116-26. PMID:20826338<ref>PMID:20826338</ref>
-	~~[[3lh2]] is~~ a ~~12 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens] and [http~~:~~//en~~.~~wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:020826338</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
-	[[Category: Holmes, M A.]]	+	[[Category: Holmes, M A]]
	[[Category: Epitope-scaffold]]		[[Category: Epitope-scaffold]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA: Protected "3lh2" [edit=sysop:move=sysop]

OCA — Thu, 04 Apr 2013 20:16:35 GMT

Protected "3lh2" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:16, 4 April 2013

OCA at 20:16, 4 April 2013

OCA — Thu, 04 Apr 2013 20:16:33 GMT

←Older revision		Revision as of 20:16, 4 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3lh2.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3lh2", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3lh2\| PDB=3lh2 \| SCENE= }}		{{STRUCTURE_3lh2\| PDB=3lh2 \| SCENE= }}
-
	===Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex===		===Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20826338}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20826338 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20826338}}		{{ABSTRACT_PUBMED_20826338}}

	==About this Structure==		==About this Structure==
-	~~3LH2~~ is a 12 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA].	+	[[3lh2]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20826338~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020826338</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Synthetic construct]]		[[Category: Synthetic construct]]
Line 29:		Line 13:
	[[Category: Epitope-scaffold]]		[[Category: Epitope-scaffold]]
	[[Category: Immune system]]		[[Category: Immune system]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:45:25 2010''

OCA at 11:36, 22 September 2010

OCA — Wed, 22 Sep 2010 11:36:27 GMT

←Older revision		Revision as of 11:36, 22 September 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3lh2.jpg\|left\|200px]]

-	The ~~entry 3lh2~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3lh2", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3lh2\| PDB=3lh2 \| SCENE= }}

-	~~Authors: Holmes, M.A.~~	+	===Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex===

-	Description: Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~May 5 11~~:36:31 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20826338}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20826338 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20826338}}
		+
		+	==About this Structure==
		+	3LH2 is a 12 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LH2 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20826338</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Synthetic construct]]
		+	[[Category: Holmes, M A.]]
		+	[[Category: Epitope-scaffold]]
		+	[[Category: Immune system]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:45:25 2010''

OCA at 08:36, 5 May 2010

OCA — Wed, 05 May 2010 08:36:31 GMT

←Older revision		Revision as of 08:36, 5 May 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3lh2 is ON HOLD	+	The entry 3lh2 is ON HOLD until Paper Publication

	Authors: Holmes, M.A.		Authors: Holmes, M.A.
Line 7:		Line 7:
	Description: Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex		Description: Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb~~ ~~3 09~~:19:35 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:36:31 2010''

OCA at 07:19, 3 February 2010

OCA — Wed, 03 Feb 2010 07:19:35 GMT

←Older revision		Revision as of 07:19, 3 February 2010
Line 3:		Line 3:
	The entry 3lh2 is ON HOLD		The entry 3lh2 is ON HOLD

-	Authors: ~~Correia, B.E., Ban, Y.A.,~~ Holmes, M.A., Xu, H., Ellingson, K., Kraft, Z., Friend, D.J., Carrico, C., Boni, E., Sather, N., Zenobia, C., Burke, K.Y., Bradley-Hewitt, T., Bruhn-Johannsen, J.F., Kalyuzhniy, O., Baker, D., Strong, R.K., Stamatatos, L., Schief	+	Authors: Holmes, M.A.

	Description: Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex		Description: Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jan 27 19~~:19:26 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:19:35 2010''