3ljb - Revision history

OCA at 10:20, 21 February 2024

OCA — Wed, 21 Feb 2024 10:20:56 GMT

←Older revision		Revision as of 10:20, 21 February 2024
Line 1:		Line 1:

	==Structural basis of oligomerisation in the MxA stalk==		==Structural basis of oligomerisation in the MxA stalk==
-	<StructureSection load='3ljb' size='340' side='right' caption='[[3ljb]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='3ljb' size='340' side='right'caption='[[3ljb]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ljb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LJB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ljb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJB FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~MX1 (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=9606 HUMAN])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [~~http~~://pdbe.org/3ljb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ljb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [https://pdbe.org/3ljb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [https://www.ebi.ac.uk/pdbsum/3ljb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MX1_HUMAN MX1_HUMAN]] Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.<ref>PMID:20603636</ref> <ref>PMID:11880649</ref> <ref>PMID:15047845</ref> <ref>PMID:14752052</ref> <ref>PMID:15355513</ref> <ref>PMID:14687945</ref> <ref>PMID:15757897</ref> <ref>PMID:16413306</ref> <ref>PMID:16202617</ref> <ref>PMID:17374778</ref> <ref>PMID:18668195</ref> <ref>PMID:19109387</ref> <ref>PMID:21900240</ref> <ref>PMID:21992152</ref>	+	[https://www.uniprot.org/uniprot/MX1_HUMAN MX1_HUMAN] Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.<ref>PMID:20603636</ref> <ref>PMID:11880649</ref> <ref>PMID:15047845</ref> <ref>PMID:14752052</ref> <ref>PMID:15355513</ref> <ref>PMID:14687945</ref> <ref>PMID:15757897</ref> <ref>PMID:16413306</ref> <ref>PMID:16202617</ref> <ref>PMID:17374778</ref> <ref>PMID:18668195</ref> <ref>PMID:19109387</ref> <ref>PMID:21900240</ref> <ref>PMID:21992152</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ljb ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ljb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The interferon-inducible dynamin-like myxovirus resistance protein 1 (MxA; also called MX1) GTPase is a key mediator of cell-autonomous innate immunity against pathogens such as influenza viruses. MxA partially localizes to COPI-positive membranes of the smooth endoplasmic reticulum-Golgi intermediate compartment. At the point of infection, it redistributes to sites of viral replication and promotes missorting of essential viral constituents. It has been proposed that the middle domain and the GTPase effector domain of dynamin-like GTPases constitute a stalk that mediates oligomerization and transmits conformational changes from the G domain to the target structure; however, the molecular architecture of this stalk has remained elusive. Here we report the crystal structure of the stalk of human MxA, which folds into a four-helical bundle. This structure tightly oligomerizes in the crystal in a criss-cross pattern involving three distinct interfaces and one loop. Mutations in each of these interaction sites interfere with native assembly, oligomerization, membrane binding and antiviral activity of MxA. On the basis of these results, we propose a structural model for dynamin oligomerization and stimulated GTP hydrolysis that is consistent with previous structural predictions and has functional implications for all members of the dynamin family.
-
-	Structural basis of oligomerization in the stalk region of dynamin-like MxA.,Gao S, von der Malsburg A, Paeschke S, Behlke J, Haller O, Kochs G, Daumke O Nature. 2010 May 27;465(7297):502-6. Epub 2010 Apr 28. PMID:20428112<ref>PMID:20428112</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3ljb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[GTP-binding protein\|GTP-binding protein]]	+	*[[GTP-binding protein 3D structures\|GTP-binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Daumke, O~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Gao, S~~]]	+	[[Category: Daumke O]]
-	[[Category: ~~Antiviral protein]]~~	+	[[Category: Gao S]]
-	~~[[Category: Four-helix-bundle]]~~	+
-	~~[[Category: Gtp-binding~~]]	+

OCA at 06:54, 2 January 2019

OCA — Wed, 02 Jan 2019 06:54:22 GMT

←Older revision		Revision as of 06:54, 2 January 2019
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljb_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 08:58, 4 August 2016

OCA — Thu, 04 Aug 2016 08:58:52 GMT

←Older revision		Revision as of 08:58, 4 August 2016
Line 1:		Line 1:
		+
	==Structural basis of oligomerisation in the MxA stalk==		==Structural basis of oligomerisation in the MxA stalk==
	<StructureSection load='3ljb' size='340' side='right' caption='[[3ljb]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='3ljb' size='340' side='right' caption='[[3ljb]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJB FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [http://www.ebi.ac.uk/pdbsum/3ljb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [http://pdbe.org/3ljb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [http://www.ebi.ac.uk/pdbsum/3ljb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ljb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ljb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Daumke, O]]		[[Category: Daumke, O]]
	[[Category: Gao, S]]		[[Category: Gao, S]]

OCA at 07:35, 25 December 2014

OCA — Thu, 25 Dec 2014 07:35:12 GMT

←Older revision		Revision as of 07:35, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [http://www.ebi.ac.uk/pdbsum/3ljb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [http://www.ebi.ac.uk/pdbsum/3ljb PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MX1_HUMAN MX1_HUMAN]] Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus (THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus (LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus (IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.<ref>PMID:20603636</ref> <ref>PMID:11880649</ref> <ref>PMID:15047845</ref> <ref>PMID:14752052</ref> <ref>PMID:15355513</ref> <ref>PMID:14687945</ref> <ref>PMID:15757897</ref> <ref>PMID:16413306</ref> <ref>PMID:16202617</ref> <ref>PMID:17374778</ref> <ref>PMID:18668195</ref> <ref>PMID:19109387</ref> <ref>PMID:21900240</ref> <ref>PMID:21992152</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:15, 9 December 2014

OCA — Tue, 09 Dec 2014 09:15:58 GMT

←Older revision		Revision as of 09:15, 9 December 2014
Line 1:		Line 1:
-	[[~~Image~~:3ljb.~~png\|left~~\|200px]]	+	==Structural basis of oligomerisation in the MxA stalk==
		+	<StructureSection load='3ljb' size='340' side='right' caption='[[3ljb]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJB FirstGlance]. <br>
		+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MX1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljb RCSB], [http://www.ebi.ac.uk/pdbsum/3ljb PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljb_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The interferon-inducible dynamin-like myxovirus resistance protein 1 (MxA; also called MX1) GTPase is a key mediator of cell-autonomous innate immunity against pathogens such as influenza viruses. MxA partially localizes to COPI-positive membranes of the smooth endoplasmic reticulum-Golgi intermediate compartment. At the point of infection, it redistributes to sites of viral replication and promotes missorting of essential viral constituents. It has been proposed that the middle domain and the GTPase effector domain of dynamin-like GTPases constitute a stalk that mediates oligomerization and transmits conformational changes from the G domain to the target structure; however, the molecular architecture of this stalk has remained elusive. Here we report the crystal structure of the stalk of human MxA, which folds into a four-helical bundle. This structure tightly oligomerizes in the crystal in a criss-cross pattern involving three distinct interfaces and one loop. Mutations in each of these interaction sites interfere with native assembly, oligomerization, membrane binding and antiviral activity of MxA. On the basis of these results, we propose a structural model for dynamin oligomerization and stimulated GTP hydrolysis that is consistent with previous structural predictions and has functional implications for all members of the dynamin family.

-	~~{{STRUCTURE_3ljb\| PDB=3ljb \| SCENE= }}~~	+	Structural basis of oligomerization in the stalk region of dynamin-like MxA.,Gao S, von der Malsburg A, Paeschke S, Behlke J, Haller O, Kochs G, Daumke O Nature. 2010 May 27;465(7297):502-6. Epub 2010 Apr 28. PMID:20428112<ref>PMID:20428112</ref>

-	~~===Structural basis~~ of ~~oligomerisation in~~ the ~~MxA stalk===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20428112}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3ljb]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].~~	+

	==See Also==		==See Also==
	*[[GTP-binding protein\|GTP-binding protein]]		*[[GTP-binding protein\|GTP-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020428112<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Daumke, O.]]	+	[[Category: Daumke, O]]
-	[[Category: Gao, S.]]	+	[[Category: Gao, S]]
	[[Category: Antiviral protein]]		[[Category: Antiviral protein]]
	[[Category: Four-helix-bundle]]		[[Category: Four-helix-bundle]]
	[[Category: Gtp-binding]]		[[Category: Gtp-binding]]

OCA at 14:15, 20 October 2012

OCA — Sat, 20 Oct 2012 14:15:05 GMT

←Older revision		Revision as of 14:15, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3ljb]] is a 2 chain structure ~~of [[GTP-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].	+	[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].

	==See Also==		==See Also==

OCA at 14:32, 26 July 2012

OCA — Thu, 26 Jul 2012 14:32:54 GMT

←Older revision		Revision as of 14:32, 26 July 2012
Line 1:		Line 1:
	[[Image:3ljb.png\|left\|200px]]		[[Image:3ljb.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ljb", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ljb\| PDB=3ljb \| SCENE= }}		{{STRUCTURE_3ljb\| PDB=3ljb \| SCENE= }}

	===Structural basis of oligomerisation in the MxA stalk===		===Structural basis of oligomerisation in the MxA stalk===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20428112}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20428112 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_20428112}}		{{ABSTRACT_PUBMED_20428112}}

	==About this Structure==		==About this Structure==
-	[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].	+	[[3ljb]] is a 2 chain structure of [[GTP-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].
		+
		+	==See Also==
		+	*[[GTP-binding protein\|GTP-binding protein]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20428112~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020428112</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Daumke, O.]]		[[Category: Daumke, O.]]

OCA: Protected "3ljb" [edit=sysop:move=sysop]

OCA — Wed, 29 Dec 2010 18:30:58 GMT

Protected "3ljb" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:30, 29 December 2010

OCA at 18:30, 29 December 2010

OCA — Wed, 29 Dec 2010 18:30:56 GMT

←Older revision		Revision as of 18:30, 29 December 2010
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-	{{Seed}}
	[[Image:3ljb.png\|left\|200px]]		[[Image:3ljb.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3LJB~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].	+	[[3ljb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].

	==Reference==		==Reference==
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	[[Category: Four-helix-bundle]]		[[Category: Four-helix-bundle]]
	[[Category: Gtp-binding]]		[[Category: Gtp-binding]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:53:11 2010''

OCA at 06:48, 10 June 2010

OCA — Thu, 10 Jun 2010 06:48:24 GMT

←Older revision		Revision as of 06:48, 10 June 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3ljb.~~jpg~~\|left\|200px]]	+	[[Image:3ljb.png\|left\|200px]]

	<!--		<!--
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	===Structural basis of oligomerisation in the MxA stalk===		===Structural basis of oligomerisation in the MxA stalk===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20428112}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20428112 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20428112}}

	==About this Structure==		==About this Structure==
	3LJB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].		3LJB is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJB OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20428112</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Daumke, O.]]		[[Category: Daumke, O.]]
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	[[Category: Gtp-binding]]		[[Category: Gtp-binding]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed May 5 12~~:09:15 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:53:11 2010''