3ljj - Revision history

OCA at 08:38, 6 September 2023

OCA — Wed, 06 Sep 2023 08:38:31 GMT

←Older revision		Revision as of 08:38, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3ljj' size='340' side='right'caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3ljj' size='340' side='right'caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10U:(S)-N-(4-CARBAMIMIDOYLBENZYL)-1-(2-(CYCLOPENTYLAMINO)ETHANOYL)PYRROLIDINE-2-CARBOXAMIDE'>10U</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zft\|2zft]], [[2zfs\|2zfs]], [[2zq1\|2zq1]], [[2zq2\|2zq2]], [[2zhd\|2zhd]], [[3biu\|3biu]], [[3ljo\|3ljo]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=10U:(S)-N-(4-CARBAMIMIDOYLBENZYL)-1-(2-(CYCLOPENTYLAMINO)ETHANOYL)PYRROLIDINE-2-CARBOXAMIDE'>10U</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ljj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljj OCA], [https://pdbe.org/3ljj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ljj RCSB], [https://www.ebi.ac.uk/pdbsum/3ljj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljj ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ljj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljj OCA], [~~http~~://pdbe.org/3ljj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ljj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ljj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljj ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 31:

	==See Also==		==See Also==
-	*[[Trypsin\|Trypsin]]	+	*[[Trypsin 3D structures\|Trypsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bovin~~]]	+	[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Trypsin]]~~	+	[[Category: Heine A]]
-	[[Category: Heine, A]]	+	[[Category: Klebe G]]
-	[[Category: Klebe, G]]	+	[[Category: Wegscheid-Gerlach C]]
-	[[Category: Wegscheid-Gerlach, C]]	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Serine protease~~]]	+

OCA at 11:12, 17 July 2019

OCA — Wed, 17 Jul 2019 11:12:46 GMT

←Older revision		Revision as of 11:12, 17 July 2019
Line 1:		Line 1:

	==Bovine trypsin in complex with UB-THR 10==		==Bovine trypsin in complex with UB-THR 10==
-	<StructureSection load='3ljj' size='340' side='right' caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='3ljj' size='340' side='right'caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Bovin]]		[[Category: Bovin]]
		+	[[Category: Large Structures]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Heine, A]]		[[Category: Heine, A]]

OCA at 06:33, 2 January 2019

OCA — Wed, 02 Jan 2019 06:33:13 GMT

←Older revision		Revision as of 06:33, 2 January 2019
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 20:19, 9 December 2016

OCA — Fri, 09 Dec 2016 20:19:22 GMT

←Older revision		Revision as of 20:19, 9 December 2016
Line 1:		Line 1:
		+
	==Bovine trypsin in complex with UB-THR 10==		==Bovine trypsin in complex with UB-THR 10==
	<StructureSection load='3ljj' size='340' side='right' caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3ljj' size='340' side='right' caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10U:(S)-N-(4-CARBAMIMIDOYLBENZYL)-1-(2-(CYCLOPENTYLAMINO)ETHANOYL)PYRROLIDINE-2-CARBOXAMIDE'>10U</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10U:(S)-N-(4-CARBAMIMIDOYLBENZYL)-1-(2-(CYCLOPENTYLAMINO)ETHANOYL)PYRROLIDINE-2-CARBOXAMIDE'>10U</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zft\|2zft]], [[2zfs\|2zfs]], [[2zq1\|2zq1]], [[2zq2\|2zq2]], [[2zhd\|2zhd]], [[3biu\|3biu]], [[3ljo\|3ljo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zft\|2zft]], [[2zfs\|2zfs]], [[2zq1\|2zq1]], [[2zq2\|2zq2]], [[2zhd\|2zhd]], [[3biu\|3biu]], [[3ljo\|3ljo]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljj RCSB], [http://www.ebi.ac.uk/pdbsum/3ljj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljj OCA], [http://pdbe.org/3ljj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ljj RCSB], [http://www.ebi.ac.uk/pdbsum/3ljj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ljj ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ljj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ljj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bos taurus~~]]	+	[[Category: Bovin]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Heine, A]]		[[Category: Heine, A]]

OCA at 08:29, 9 December 2014

OCA — Tue, 09 Dec 2014 08:29:25 GMT

←Older revision		Revision as of 08:29, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3ljj.~~png~~\|~~left~~\|200px]]	+	==Bovine trypsin in complex with UB-THR 10==
		+	<StructureSection load='3ljj' size='340' side='right' caption='[[3ljj]], [[Resolution\|resolution]] 1.55Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=10U:(S)-N-(4-CARBAMIMIDOYLBENZYL)-1-(2-(CYCLOPENTYLAMINO)ETHANOYL)PYRROLIDINE-2-CARBOXAMIDE'>10U</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2zft\|2zft]], [[2zfs\|2zfs]], [[2zq1\|2zq1]], [[2zq2\|2zq2]], [[2zhd\|2zhd]], [[3biu\|3biu]], [[3ljo\|3ljo]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ljj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ljj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ljj RCSB], [http://www.ebi.ac.uk/pdbsum/3ljj PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lj/3ljj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A congeneric series of benzamidine-type ligands with a central proline moiety and a terminal cycloalkyl group-linked by a secondary amine, ether, or methylene bridge-was synthesized as trypsin inhibitors. This series of inhibitors was investigated by isothermal titration calorimetry, crystal structure analysis in two crystal forms, and molecular dynamics simulations. Even though all of these congeneric ligands exhibited essentially the same affinity for trypsin, their binding profiles at the structural, dynamic, and thermodynamic levels are very distinct. The ligands display a pronounced enthalpy/entropy compensation that results in a nearly unchanged free energy of binding, even though individual enthalpy and entropy terms change significantly across the series. Crystal structures revealed that the secondary amine-linked analogs scatter over two distinct conformational families of binding modes that occupy either the inside or the outside the protein's S3/S4 specificity pocket. In contrast, the ether-linked and methylene-linked ligands preferentially occupy the hydrophobic specificity pocket. This also explains why the latter ligands could only be crystallized in the conformationally restricting closed crystal form whereas the derivative with the highest residual mobility in the series escaped our attempts to crystallize it in the closed form; instead, a well-resolved structure could only be achieved in the open form with the ligand in disordered orientation. These distinct binding modes are supported by molecular dynamics simulations and correlate with the shifting enthalpic/entropic signatures of ligand binding. The examples demonstrate that, at the molecular level, binding modes and thermodynamic binding signatures can be very different even for closely related ligands. However, deviating binding profiles provide the opportunity to optimally address a given target.

-	~~{{STRUCTURE_3ljj\| PDB=3ljj \| SCENE= }}~~	+	Congeneric but Still Distinct: How Closely Related Trypsin Ligands Exhibit Different Thermodynamic and Structural Properties.,Brandt T, Holzmann N, Muley L, Khayat M, Wegscheid-Gerlach C, Baum B, Heine A, Hangauer D, Klebe G J Mol Biol. 2010 Nov 25. PMID:21111747<ref>PMID:21111747</ref>

-	~~===Bovine trypsin in complex with UB-THR 10===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21111747}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3ljj]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bos_taurus Bos taurus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].~~	+

	==See Also==		==See Also==
	*[[Trypsin\|Trypsin]]		*[[Trypsin\|Trypsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021111747<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
-	[[Category: Heine, A.]]	+	[[Category: Heine, A]]
-	[[Category: Klebe, G.]]	+	[[Category: Klebe, G]]
-	[[Category: Wegscheid-Gerlach, C.]]	+	[[Category: Wegscheid-Gerlach, C]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Metal-binding]]		[[Category: Metal-binding]]
	[[Category: Serine protease]]		[[Category: Serine protease]]

OCA at 17:22, 20 October 2012

OCA — Sat, 20 Oct 2012 17:22:16 GMT

←Older revision		Revision as of 17:22, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3ljj]] is a 1 chain structure ~~of [[Trypsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].	+	[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].

	==See Also==		==See Also==

OCA at 00:41, 27 July 2012

OCA — Fri, 27 Jul 2012 00:41:32 GMT

←Older revision		Revision as of 00:41, 27 July 2012
Line 1:		Line 1:
	[[Image:3ljj.png\|left\|200px]]		[[Image:3ljj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ljj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ljj\| PDB=3ljj \| SCENE= }}		{{STRUCTURE_3ljj\| PDB=3ljj \| SCENE= }}

	===Bovine trypsin in complex with UB-THR 10===		===Bovine trypsin in complex with UB-THR 10===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21111747}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21111747 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21111747}}		{{ABSTRACT_PUBMED_21111747}}

	==About this Structure==		==About this Structure==
-	[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].	+	[[3ljj]] is a 1 chain structure of [[Trypsin]] with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].
		+
		+	==See Also==
		+	*[[Trypsin\|Trypsin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21111747~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021111747</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
Line 28:		Line 20:
	[[Category: Klebe, G.]]		[[Category: Klebe, G.]]
	[[Category: Wegscheid-Gerlach, C.]]		[[Category: Wegscheid-Gerlach, C.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Metal-binding]]
		+	[[Category: Serine protease]]

OCA: Protected "3ljj" [edit=sysop:move=sysop]

OCA — Wed, 05 Jan 2011 15:34:47 GMT

Protected "3ljj" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:34, 5 January 2011

OCA at 15:34, 5 January 2011

OCA — Wed, 05 Jan 2011 15:34:46 GMT

←Older revision		Revision as of 15:34, 5 January 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3ljj.png\|left\|200px]]
-	[[Image:3ljj.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	===Bovine trypsin in complex with UB-THR 10===		===Bovine trypsin in complex with UB-THR 10===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21111747}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21111747 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21111747}}

	==About this Structure==		==About this Structure==
-	~~3LJJ~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].	+	[[3ljj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21111747</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
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	[[Category: Klebe, G.]]		[[Category: Klebe, G.]]
	[[Category: Wegscheid-Gerlach, C.]]		[[Category: Wegscheid-Gerlach, C.]]
-	[[Category: Hydrolase-hydrolase inhibitor complex]]
-	[[Category: Metal-binding]]
-	[[Category: Serine protease]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:05:07 2010''

OCA at 02:55, 6 October 2010

OCA — Wed, 06 Oct 2010 02:55:37 GMT

←Older revision		Revision as of 02:55, 6 October 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ljj.jpg\|left\|200px]]

-	The ~~entry 3ljj~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ljj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ljj\| PDB=3ljj \| SCENE= }}

-	~~Authors: Wegscheid~~-~~Gerlach, C., Heine, A., Klebe, G.~~	+	===Bovine trypsin in complex with UB-THR 10===

-	Description: Bovine trypsin in complex with UB-THR 10 (CASP Target)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb~~ ~~3 09~~:20:23 2010''	+	==About this Structure==
		+	3LJJ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJJ OCA].
		+	[[Category: Bos taurus]]
		+	[[Category: Trypsin]]
		+	[[Category: Heine, A.]]
		+	[[Category: Klebe, G.]]
		+	[[Category: Wegscheid-Gerlach, C.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Metal-binding]]
		+	[[Category: Serine protease]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:05:07 2010''