3lju - Revision history

OCA at 08:38, 6 September 2023

OCA — Wed, 06 Sep 2023 08:38:46 GMT

←Older revision		Revision as of 08:38, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3lju' size='340' side='right'caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3lju' size='340' side='right'caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.702Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [https://pdbe.org/3lju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [https://www.ebi.ac.uk/pdbsum/3lju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lju ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [https://pdbe.org/3lju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [https://www.ebi.ac.uk/pdbsum/3lju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lju ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>	+	[https://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bochkarev, A]]	+	[[Category: Bochkarev A]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Edwards AM]]
-	[[Category: MacKenzie, F]]	+	[[Category: MacKenzie F]]
-	[[Category: Park, H]]	+	[[Category: Park H]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Shen L]]
-	[[Category: Shen, L]]	+	[[Category: Tempel W]]
-	[[Category: Tempel, W]]	+	[[Category: Tong Y]]
-	[[Category: Tong, Y]]	+	[[Category: Weigelt J]]
-	[[Category: Weigelt, J]]	+
-	~~[[Category: Gap]]~~	+
-	~~[[Category: Gtpase activation]]~~	+
-	~~[[Category: Hydrolase activator]]~~	+
-	~~[[Category: Metal-binding]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Phosphoprotein]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Zinc-finger~~]]	+

OCA at 13:40, 4 May 2022

OCA — Wed, 04 May 2022 13:40:46 GMT

←Older revision		Revision as of 13:40, 4 May 2022
Line 1:		Line 1:

	==Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3==		==Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3==
-	<StructureSection load='3lju' size='340' side='right' caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='3lju' size='340' side='right'caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LJU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LJU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [~~http~~://pdbe.org/3lju PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3lju PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3lju ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [https://pdbe.org/3lju PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [https://www.ebi.ac.uk/pdbsum/3lju PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lju ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>	+	[[https://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bochkarev, A]]		[[Category: Bochkarev, A]]

OCA at 04:22, 5 August 2016

OCA — Fri, 05 Aug 2016 04:22:35 GMT

←Older revision		Revision as of 04:22, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3==		==Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3==
	<StructureSection load='3lju' size='340' side='right' caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3lju' size='340' side='right' caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [http://www.ebi.ac.uk/pdbsum/3lju PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [http://pdbe.org/3lju PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [http://www.ebi.ac.uk/pdbsum/3lju PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lju ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3lju" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bochkarev, A]]		[[Category: Bochkarev, A]]

OCA at 15:47, 25 December 2014

OCA — Thu, 25 Dec 2014 15:47:18 GMT

←Older revision		Revision as of 15:47, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [http://www.ebi.ac.uk/pdbsum/3lju PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [http://www.ebi.ac.uk/pdbsum/3lju PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 16:03, 18 December 2014

OCA — Thu, 18 Dec 2014 16:03:53 GMT

←Older revision		Revision as of 16:03, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3lju\| PDB=3lju \| SCENE= }}~~	+	==Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3==
-	===Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3===	+	<StructureSection load='3lju' size='340' side='right' caption='[[3lju]], [[Resolution\|resolution]] 1.70Å' scene=''>
-	{{~~ABSTRACT_PUBMED_21057110~~}}	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3lju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LJU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IP9:(2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}PROPANE-1,2-DIYL+DIOCTANOATE'>IP9</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ADAP1, CENTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lju FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lju OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lju RCSB], [http://www.ebi.ac.uk/pdbsum/3lju PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phosphatidylinositol 3,4,5-triphosphate (PIP3) plays a key role in neuronal polarization and axon formation. PIP3-containing vesicles are transported to axon tips by the kinesin KIF13B via an adaptor protein, centaurin alpha1 (CENTA1). KIF13B interacts with CENTA1 through its forkhead-associated (FHA) domain. We solved the crystal structures of CENTA1 in ligand-free, KIF13B-FHA domain-bound, and PIP3 head group (IP4)-bound conformations, and the CENTA1/KIF13B-FHA/IP4 ternary complex. The first pleckstrin homology (PH) domain of CENTA1 specifically binds to PIP3, while the second binds to both PIP3 and phosphatidylinositol 3,4-biphosphate (PI(3,4)P(2)). The FHA domain of KIF13B interacts with the PH1 domain of one CENTA1 molecule and the ArfGAP domain of a second CENTA1 molecule in a threonine phosphorylation-independent fashion. We propose that full-length KIF13B and CENTA1 form heterotetramers that can bind four phosphoinositide molecules in the vesicle and transport it along the microtubule.

-	~~==Function==~~	+	Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin {alpha}1.,Tong Y, Tempel W, Wang H, Yamada K, Shen L, Senisterra GA, Mackenzie F, Chishti AH, Park HW Proc Natl Acad Sci U S A. 2010 Nov 5. PMID:21057110<ref>PMID:21057110</ref>
-	~~[[http://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase~~-~~activating protein for~~ the ~~ADP ribosylation factor family (Probable)~~. ~~Binds phosphatidylinositol 3~~,4,~~5-trisphosphate (PtdInsP3) and inositol 1~~,3,4,5~~-tetrakisphosphate (InsP4)~~.~~<ref>~~PMID:~~10448098</ref>~~ <ref>PMID:~~10333475~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3lju]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:021057110</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Bochkarev, A.]]	+	[[Category: Bochkarev, A]]
-	[[Category: Bountra, C.]]	+	[[Category: Bountra, C]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: MacKenzie, F.]]	+	[[Category: MacKenzie, F]]
-	[[Category: Park, H.]]	+	[[Category: Park, H]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Shen, L.]]	+	[[Category: Shen, L]]
-	[[Category: Tempel, W.]]	+	[[Category: Tempel, W]]
-	[[Category: Tong, Y.]]	+	[[Category: Tong, Y]]
-	[[Category: Weigelt, J.]]	+	[[Category: Weigelt, J]]
	[[Category: Gap]]		[[Category: Gap]]
	[[Category: Gtpase activation]]		[[Category: Gtpase activation]]
Line 30:		Line 38:
	[[Category: Phosphoprotein]]		[[Category: Phosphoprotein]]
	[[Category: Sgc]]		[[Category: Sgc]]
-	[[Category: Structural genomics consortium]]
	[[Category: Zinc-finger]]		[[Category: Zinc-finger]]

OCA: Protected "3lju" [edit=sysop:move=sysop]

OCA — Thu, 04 Apr 2013 20:36:24 GMT

Protected "3lju" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:36, 4 April 2013

OCA at 20:36, 4 April 2013

OCA — Thu, 04 Apr 2013 20:36:16 GMT

←Older revision		Revision as of 20:36, 4 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3lju.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3lju", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3lju\| PDB=3lju \| SCENE= }}		{{STRUCTURE_3lju\| PDB=3lju \| SCENE= }}
-
	===Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3===		===Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3===
		+	{{ABSTRACT_PUBMED_21057110}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/ADAP1_HUMAN ADAP1_HUMAN]] GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).<ref>PMID:10448098</ref> <ref>PMID:10333475</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21057110}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 21057110 is~~ the ~~PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_21057110}}~~	+

	==About this Structure==		==About this Structure==
-	~~3LJU~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA].	+	[[3lju]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21057110~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021057110</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]
Line 45:		Line 32:
	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
	[[Category: Zinc-finger]]		[[Category: Zinc-finger]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:15:05 2010''

OCA at 05:02, 15 December 2010

OCA — Wed, 15 Dec 2010 05:02:46 GMT

←Older revision		Revision as of 05:02, 15 December 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3lju.~~jpg~~\|left\|200px]]	+	[[Image:3lju.png\|left\|200px]]

	<!--		<!--
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	[[Category: Zinc-finger]]		[[Category: Zinc-finger]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 24 14~~:14:22 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:15:05 2010''

OCA at 11:02, 24 November 2010

OCA — Wed, 24 Nov 2010 11:02:52 GMT

←Older revision		Revision as of 11:02, 24 November 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3lju.jpg\|left\|200px]]

-	The ~~entry 3lju~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3lju", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3lju\| PDB=3lju \| SCENE= }}

-	~~Authors: Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)~~	+	===Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3===

-	Description: Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Feb 3 09~~:20:30 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21057110}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21057110 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21057110}}
		+
		+	==About this Structure==
		+	3LJU is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LJU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21057110</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Bochkarev, A.]]
		+	[[Category: Bountra, C.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: MacKenzie, F.]]
		+	[[Category: Park, H.]]
		+	[[Category: SGC, Structural Genomics Consortium.]]
		+	[[Category: Shen, L.]]
		+	[[Category: Tempel, W.]]
		+	[[Category: Tong, Y.]]
		+	[[Category: Weigelt, J.]]
		+	[[Category: Gap]]
		+	[[Category: Gtpase activation]]
		+	[[Category: Hydrolase activator]]
		+	[[Category: Metal-binding]]
		+	[[Category: Nucleus]]
		+	[[Category: Phosphoprotein]]
		+	[[Category: Sgc]]
		+	[[Category: Structural genomics consortium]]
		+	[[Category: Zinc-finger]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:14:22 2010''

OCA: New page: '''Unreleased structure''' The entry 3lju is ON HOLD Authors: Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Pa...

OCA — Wed, 03 Feb 2010 07:20:30 GMT

New page: '''Unreleased structure''' The entry 3lju is ON HOLD Authors: Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Pa...

New page

'''Unreleased structure'''

The entry 3lju is ON HOLD

Authors: Shen, L., Tong, Y., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)

Description: Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 3 09:20:30 2010''