3lk3 - Revision history

OCA at 16:24, 1 November 2023

OCA — Wed, 01 Nov 2023 16:24:01 GMT

←Older revision		Revision as of 16:24, 1 November 2023
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	<StructureSection load='3lk3' size='340' side='right'caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>		<StructureSection load='3lk3' size='340' side='right'caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Chick Chick~~] and [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3lk2\|3lk2]], [[3lk4\|3lk4]]</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.68Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">CAPZA1 ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&srchmode=5&id=9031 CHICK]), CAPZB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK]), CARMIL, LRRC16, LRRC16A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [https://pdbe.org/3lk3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [https://www.ebi.ac.uk/pdbsum/3lk3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lk3 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [~~http~~://pdbe.org/3lk3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3lk3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3lk3 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. [[http://www.uniprot.org/uniprot/LR16A_HUMAN LR16A_HUMAN]] Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).<ref>PMID:16054028</ref> [[http://www.uniprot.org/uniprot/CAPZB_CHICK CAPZB_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.	+	[https://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chick~~]]	+	[[Category: Gallus gallus]]
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Cooper~~, J A~~]]	+	[[Category: Cooper JA]]
-	[[Category: Hernandez-Valladares, M]]	+	[[Category: Hernandez-Valladares M]]
-	[[Category: Kannan, B]]	+	[[Category: Kannan B]]
-	[[Category: Kim, T]]	+	[[Category: Kim T]]
-	[[Category: Robinson~~, R C~~]]	+	[[Category: Robinson RC]]
-	[[Category: Tung, A]]	+	[[Category: Tung A]]
-	~~[[Category: Actin capping]]~~	+
-	~~[[Category: Actin filament]]~~	+
-	~~[[Category: Actin-binding]]~~	+
-	~~[[Category: Actin-filament regulator]]~~	+
-	~~[[Category: Capz]]~~	+
-	~~[[Category: Carmil]]~~	+
-	~~[[Category: Cytoplasm]]~~	+
-	~~[[Category: Cytoskeleton]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Protein-protein complex]]~~	+
-	~~[[Category: Uncapping~~]]	+

OCA at 08:14, 18 December 2019

OCA — Wed, 18 Dec 2019 08:14:42 GMT

←Older revision		Revision as of 08:14, 18 December 2019
Line 1:		Line 1:

	==Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL==		==Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL==
-	<StructureSection load='3lk3' size='340' side='right' caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>	+	<StructureSection load='3lk3' size='340' side='right'caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>
Line 20:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lk3 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lk3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Capping protein (CP) regulates actin dynamics by binding the barbed ends of actin filaments. Removal of CP may be one means to harness actin polymerization for processes such as cell movement and endocytosis. Here we structurally and biochemically investigated a CP interaction (CPI) motif present in the otherwise unrelated proteins CARMIL and CD2AP. The CPI motif wraps around the stalk of the mushroom-shaped CP at a site distant from the actin-binding interface, which lies on the top of the mushroom cap. We propose that the CPI motif may act as an allosteric modulator, restricting CP to a low-affinity, filament-binding conformation. Structure-based sequence alignments extend the CPI motif-containing family to include CIN85, CKIP-1, CapZIP and a relatively uncharacterized protein, WASHCAP (FAM21). Peptides comprising these CPI motifs are able to inhibit CP and to uncap CP-bound actin filaments.
		+
		+	Structural characterization of a capping protein interaction motif defines a family of actin filament regulators.,Hernandez-Valladares M, Kim T, Kannan B, Tung A, Aguda AH, Larsson M, Cooper JA, Robinson RC Nat Struct Mol Biol. 2010 Apr;17(4):497-503. Epub 2010 Mar 28. PMID:20357771<ref>PMID:20357771</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3lk3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[Actinin\|Actinin]]	+	*[[Actinin 3D structures\|Actinin 3D structures]]
	*[[F-actin capping protein\|F-actin capping protein]]		*[[F-actin capping protein\|F-actin capping protein]]
	== References ==		== References ==
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	[[Category: Chick]]		[[Category: Chick]]
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Cooper, J A]]		[[Category: Cooper, J A]]
	[[Category: Hernandez-Valladares, M]]		[[Category: Hernandez-Valladares, M]]

OCA at 07:03, 2 January 2019

OCA — Wed, 02 Jan 2019 07:03:27 GMT

←Older revision		Revision as of 07:03, 2 January 2019
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/3lk3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/3lk3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	[[Category: Capz]]		[[Category: Capz]]
	[[Category: Carmil]]		[[Category: Carmil]]
		+	[[Category: Cytoplasm]]
	[[Category: Cytoskeleton]]		[[Category: Cytoskeleton]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Protein-protein complex]]		[[Category: Protein-protein complex]]
	[[Category: Uncapping]]		[[Category: Uncapping]]

OCA at 16:20, 4 August 2016

OCA — Thu, 04 Aug 2016 16:20:26 GMT

←Older revision		Revision as of 16:20, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL==		==Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL==
	<StructureSection load='3lk3' size='340' side='right' caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>		<StructureSection load='3lk3' size='340' side='right' caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Gallus_gallus Gallus gallus~~] and [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lk2\|3lk2]], [[3lk4\|3lk4]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lk2\|3lk2]], [[3lk4\|3lk4]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CAPZA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 ~~Gallus gallus~~]), CAPZB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 ~~Gallus gallus~~]), CARMIL, LRRC16, LRRC16A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CAPZA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK]), CAPZB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 CHICK]), CARMIL, LRRC16, LRRC16A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lk3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [http://pdbe.org/3lk3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lk3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3lk3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lk3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Gallus gallus~~]]	+	[[Category: Chick]]
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Cooper, J A]]		[[Category: Cooper, J A]]
	[[Category: Hernandez-Valladares, M]]		[[Category: Hernandez-Valladares, M]]

OCA at 10:56, 25 December 2014

OCA — Thu, 25 Dec 2014 10:56:44 GMT

←Older revision		Revision as of 10:56, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lk3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lk3 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CAZA1_CHICK CAZA1_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. [[http://www.uniprot.org/uniprot/LR16A_HUMAN LR16A_HUMAN]] Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity).<ref>PMID:16054028</ref> [[http://www.uniprot.org/uniprot/CAPZB_CHICK CAPZB_CHICK]] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 21:		Line 23:
	*[[Actinin\|Actinin]]		*[[Actinin\|Actinin]]
	*[[F-actin capping protein\|F-actin capping protein]]		*[[F-actin capping protein\|F-actin capping protein]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:34, 9 December 2014

OCA — Tue, 09 Dec 2014 09:34:32 GMT

←Older revision		Revision as of 09:34, 9 December 2014
Line 1:		Line 1:
-	~~[[Image:3lk3.png\|left\|200px]]~~	+	==Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL==
-		+	<StructureSection load='3lk3' size='340' side='right' caption='[[3lk3]], [[Resolution\|resolution]] 2.68Å' scene=''>
-	~~{{STRUCTURE_3lk3\| PDB=3lk3 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LK3 FirstGlance]. <br>
-	===Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL===	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lk2\|3lk2]], [[3lk4\|3lk4]]</td></tr>
-		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CAPZA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus]), CAPZB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus]), CARMIL, LRRC16, LRRC16A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	~~{{ABSTRACT_PUBMED_020357771}}~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lk3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lk3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lk3 RCSB], [http://www.ebi.ac.uk/pdbsum/3lk3 PDBsum]</span></td></tr>
-		+	</table>
-	==~~About this Structure~~==	+	== Evolutionary Conservation ==
-	[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].	+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lk/3lk3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
	*[[Actinin\|Actinin]]		*[[Actinin\|Actinin]]
	*[[F-actin capping protein\|F-actin capping protein]]		*[[F-actin capping protein\|F-actin capping protein]]
-		+	__TOC__
-	~~==Reference==~~	+	</StructureSection>
-	~~<ref group="xtra">PMID:020357771</ref>~~<~~references group="xtra"~~/>	+
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Cooper, J A.]]	+	[[Category: Cooper, J A]]
-	[[Category: Hernandez-Valladares, M.]]	+	[[Category: Hernandez-Valladares, M]]
-	[[Category: Kannan, B.]]	+	[[Category: Kannan, B]]
-	[[Category: Kim, T.]]	+	[[Category: Kim, T]]
-	[[Category: Robinson, R C.]]	+	[[Category: Robinson, R C]]
-	[[Category: Tung, A.]]	+	[[Category: Tung, A]]
	[[Category: Actin capping]]		[[Category: Actin capping]]
	[[Category: Actin filament]]		[[Category: Actin filament]]

OCA at 15:53, 20 October 2012

OCA — Sat, 20 Oct 2012 15:53:15 GMT

←Older revision		Revision as of 15:53, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3lk3]] is a 3 chain structure ~~of [[Actinin]]~~ with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].	+	[[3lk3]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].

	==See Also==		==See Also==
	*[[Actinin\|Actinin]]		*[[Actinin\|Actinin]]
		+	*[[F-actin capping protein\|F-actin capping protein]]

	==Reference==		==Reference==

OCA: Protected "3lk3" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 19:49:09 GMT

Protected "3lk3" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:49, 26 July 2012

OCA at 19:49, 26 July 2012

OCA — Thu, 26 Jul 2012 19:49:07 GMT

←Older revision		Revision as of 19:49, 26 July 2012
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3lk3.png\|left\|200px]]
-	[[Image:3lk3.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3lk3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3lk3\| PDB=3lk3 \| SCENE= }}		{{STRUCTURE_3lk3\| PDB=3lk3 \| SCENE= }}

	===Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL===		===Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL===

		+	{{ABSTRACT_PUBMED_020357771}}

	==About this Structure==		==About this Structure==
-	~~3LK3~~ is a 3 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].	+	[[3lk3]] is a 3 chain structure of [[Actinin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].
		+
		+	==See Also==
		+	*[[Actinin\|Actinin]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:020357771</ref><references group="xtra"/>
	[[Category: Gallus gallus]]		[[Category: Gallus gallus]]
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
Line 29:		Line 29:
	[[Category: Capz]]		[[Category: Capz]]
	[[Category: Carmil]]		[[Category: Carmil]]
-	[[Category: Cytoplasm]]
	[[Category: Cytoskeleton]]		[[Category: Cytoskeleton]]
	[[Category: Protein binding]]		[[Category: Protein binding]]
	[[Category: Protein-protein complex]]		[[Category: Protein-protein complex]]
	[[Category: Uncapping]]		[[Category: Uncapping]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:50:29 2010''

OCA at 07:50, 7 April 2010

OCA — Wed, 07 Apr 2010 07:50:31 GMT

←Older revision		Revision as of 07:50, 7 April 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3lk3.jpg\|left\|200px]]

-	The ~~entry 3lk3~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3lk3", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3lk3\| PDB=3lk3 \| SCENE= }}

-	~~Authors: Hernandez-Valladares, M., Kim, T., Kannan, B., Tung, A., Cooper, J.A., Robinson, R.C.~~	+	===Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL===

-	Description: Crystal structure of CapZ bound to the CPI and CSI uncapping motifs from CARMIL

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 17 09:~~10:59 2010''	+	==About this Structure==
		+	3LK3 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LK3 OCA].
		+	[[Category: Gallus gallus]]
		+	[[Category: Homo sapiens]]
		+	[[Category: Cooper, J A.]]
		+	[[Category: Hernandez-Valladares, M.]]
		+	[[Category: Kannan, B.]]
		+	[[Category: Kim, T.]]
		+	[[Category: Robinson, R C.]]
		+	[[Category: Tung, A.]]
		+	[[Category: Actin capping]]
		+	[[Category: Actin filament]]
		+	[[Category: Actin-binding]]
		+	[[Category: Actin-filament regulator]]
		+	[[Category: Capz]]
		+	[[Category: Carmil]]
		+	[[Category: Cytoplasm]]
		+	[[Category: Cytoskeleton]]
		+	[[Category: Protein binding]]
		+	[[Category: Protein-protein complex]]
		+	[[Category: Uncapping]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 7 10:50:29 2010''