3ls4 - Revision history

OCA at 06:41, 3 April 2024

OCA — Wed, 03 Apr 2024 06:41:03 GMT

←Older revision		Revision as of 06:41, 3 April 2024
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	<StructureSection load='3ls4' size='340' side='right'caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ls4' size='340' side='right'caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ls4]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3LS4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ls4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LS4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [~~http~~://pdbe.org/3ls4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ls4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ls4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [https://pdbe.org/3ls4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [https://www.ebi.ac.uk/pdbsum/3ls4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ls4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 18:		Line 18:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ls4 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ls4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	(-)-Delta9-tetrahydrocannabinol (THC) is the main psychoactive compound found in cannabis. In this study, an anti-THC Fab fragment, designed T3, was isolated from a display library cloned from the spleen cells of a mouse immunized with a THC-bovine serum albumin conjugate, and the crystal structures of the T3 Fab in its free form and in complex with THC were determined at 1.9 A and 2.0 A resolution, respectively. The THC binding site of the T3 Fab is a narrow cavity: the n-pentyl group of THC protrudes deep into the interface area between the variable domains and the C(10) monoterpene moiety of the hapten is partially exposed to solvent. The metabolites of THC, with modifications in the C(10) monoterpene moiety, 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol and 11-hydroxy-?(9)-tetrahydrocannabinol, are bound by the T3 Fab with a higher affinity than THC. The crystal structures suggest that Ser52H and Arg53H of the T3 Fab are able to make hydrogen bonds with the metabolites, which leads to an increased binding against these metabolites. By developing a T3 Fab-Delta(9)-THC immunocomplex binding antibody from a naive antibody phage display library, the specificity of the Delta(9)-THC binding is highly increased, which allows a one-step, homogeneous, fluorescence resonance energy transfer-based sensitive immunoassay, with a detection limit of 20 ng/ml from saliva samples.
-
-	A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection.,Niemi MH, Turunen L, Pulli T, Nevanen TK, Hoyhtya M, Soderlund H, Rouvinen J, Takkinen K J Mol Biol. 2010 Jul 23;400(4):803-14. Epub 2010 May 26. PMID:20630472<ref>PMID:20630472</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3ls4" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Antibody 3D structures\|Antibody 3D structures]]		*[[Antibody 3D structures\|Antibody 3D structures]]
	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]		*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Niemi~~, M H~~]]	+	[[Category: Niemi MH]]
-	[[Category: Rouvinen, J]]	+	[[Category: Rouvinen J]]
-	~~[[Category: Antibody]]~~	+
-	~~[[Category: Cannabinoid complex]]~~	+
-	~~[[Category: Fab fragment]]~~	+
-	~~[[Category: Immune system]]~~	+
-	~~[[Category: Immunoglobulin~~]]	+

OCA at 06:37, 14 October 2020

OCA — Wed, 14 Oct 2020 06:37:27 GMT

←Older revision		Revision as of 06:37, 14 October 2020
Line 1:		Line 1:

	==Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC==		==Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC==
-	<StructureSection load='3ls4' size='340' side='right' caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3ls4' size='340' side='right'caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3LS4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3LS4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [http://pdbe.org/3ls4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ls4 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [http://pdbe.org/3ls4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ls4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:
	==See Also==		==See Also==
	*[[Antibody 3D structures\|Antibody 3D structures]]		*[[Antibody 3D structures\|Antibody 3D structures]]
		+	*[[3D structures of non-human antibody\|3D structures of non-human antibody]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Niemi, M H]]		[[Category: Niemi, M H]]

OCA at 07:10, 9 January 2019

OCA — Wed, 09 Jan 2019 07:10:27 GMT

←Older revision		Revision as of 07:10, 9 January 2019
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ls/3ls4_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ls/3ls4_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:

	==See Also==		==See Also==
-	*[[3D structures ~~of antibody~~\|3D structures ~~of antibody~~]]	+	*[[Antibody 3D structures\|Antibody 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:35, 5 August 2016

OCA — Fri, 05 Aug 2016 22:35:43 GMT

←Older revision		Revision as of 22:35, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC==		==Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC==
	<StructureSection load='3ls4' size='340' side='right' caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3ls4' size='340' side='right' caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [http://pdbe.org/3ls4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ls4 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ls4 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 25:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ls4" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[~~Antibody~~\|~~Antibody~~]]	+	*[[3D structures of antibody\|3D structures of antibody]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:47, 3 January 2015

OCA — Sat, 03 Jan 2015 22:47:55 GMT

←Older revision		Revision as of 22:47, 3 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}~~	+	==Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC==
-	===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===	+	<StructureSection load='3ls4' size='340' side='right' caption='[[3ls4]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20630472}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LS4 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TCI:(6AR,10AR)-6,6,9-TRIMETHYL-3-PENTYL-6A,7,8,10A-TETRAHYDRO-6H-BENZO[C]CHROMEN-1-OL'>TCI</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3ls5\|3ls5]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ls4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ls4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ls4 RCSB], [http://www.ebi.ac.uk/pdbsum/3ls4 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ls/3ls4_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	(-)-Delta9-tetrahydrocannabinol (THC) is the main psychoactive compound found in cannabis. In this study, an anti-THC Fab fragment, designed T3, was isolated from a display library cloned from the spleen cells of a mouse immunized with a THC-bovine serum albumin conjugate, and the crystal structures of the T3 Fab in its free form and in complex with THC were determined at 1.9 A and 2.0 A resolution, respectively. The THC binding site of the T3 Fab is a narrow cavity: the n-pentyl group of THC protrudes deep into the interface area between the variable domains and the C(10) monoterpene moiety of the hapten is partially exposed to solvent. The metabolites of THC, with modifications in the C(10) monoterpene moiety, 11-nor-9-carboxy-Delta(9)-tetrahydrocannabinol and 11-hydroxy-?(9)-tetrahydrocannabinol, are bound by the T3 Fab with a higher affinity than THC. The crystal structures suggest that Ser52H and Arg53H of the T3 Fab are able to make hydrogen bonds with the metabolites, which leads to an increased binding against these metabolites. By developing a T3 Fab-Delta(9)-THC immunocomplex binding antibody from a naive antibody phage display library, the specificity of the Delta(9)-THC binding is highly increased, which allows a one-step, homogeneous, fluorescence resonance energy transfer-based sensitive immunoassay, with a detection limit of 20 ng/ml from saliva samples.

-	~~==About this Structure==~~	+	A structural insight into the molecular recognition of a (-)-Delta9-tetrahydrocannabinol and the development of a sensitive, one-step, homogeneous immunocomplex-based assay for its detection.,Niemi MH, Turunen L, Pulli T, Nevanen TK, Hoyhtya M, Soderlund H, Rouvinen J, Takkinen K J Mol Biol. 2010 Jul 23;400(4):803-14. Epub 2010 May 26. PMID:20630472<ref>PMID:20630472</ref>
-	~~[[3ls4]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3LS4 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Antibody\|Antibody]]		*[[Antibody\|Antibody]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:020630472</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
-	[[Category: Niemi, M H.]]	+	[[Category: Niemi, M H]]
-	[[Category: Rouvinen, J.]]	+	[[Category: Rouvinen, J]]
	[[Category: Antibody]]		[[Category: Antibody]]
	[[Category: Cannabinoid complex]]		[[Category: Cannabinoid complex]]

OCA at 06:12, 22 January 2014

OCA — Wed, 22 Jan 2014 06:12:16 GMT

←Older revision		Revision as of 06:12, 22 January 2014
Line 1:		Line 1:
-	[[Image:3ls4.png\|left\|200px]]
-
	{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}		{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}
-
	===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===		===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===
-		+	{{ABSTRACT_PUBMED_20630472}}
-	{{~~ABSTRACT_PUBMED_020630472~~}}	+

	==About this Structure==		==About this Structure==
-	[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].	+	[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].

	==See Also==		==See Also==
Line 14:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:020630472</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020630472</ref><references group="xtra"/><references/>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Niemi, M H.]]		[[Category: Niemi, M H.]]
	[[Category: Rouvinen, J.]]		[[Category: Rouvinen, J.]]

OCA at 22:24, 20 October 2012

OCA — Sat, 20 Oct 2012 22:24:30 GMT

←Older revision		Revision as of 22:24, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[3ls4]] is a 2 chain structure ~~of [[Antibody]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].	+	[[3ls4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].

	==See Also==		==See Also==

OCA: Protected "3ls4" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 16:11:46 GMT

Protected "3ls4" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:11, 27 July 2012

OCA at 16:11, 27 July 2012

OCA — Fri, 27 Jul 2012 16:11:44 GMT

←Older revision		Revision as of 16:11, 27 July 2012
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-	~~{{Seed}}~~	+	[[Image:3ls4.png\|left\|200px]]
-	[[Image:3ls4.~~jpg~~\|left\|200px]]	+

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ls4", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}		{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}

	===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===		===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===

		+	{{ABSTRACT_PUBMED_020630472}}

	==About this Structure==		==About this Structure==
-	~~3LS4~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].	+	[[3ls4]] is a 2 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].
		+
		+	==See Also==
		+	*[[Antibody\|Antibody]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:020630472</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Niemi, M H.]]		[[Category: Niemi, M H.]]
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	[[Category: Immune system]]		[[Category: Immune system]]
	[[Category: Immunoglobulin]]		[[Category: Immunoglobulin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:39:07 2010''

OCA at 04:34, 2 June 2010

OCA — Wed, 02 Jun 2010 04:34:39 GMT

←Older revision		Revision as of 04:34, 2 June 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3ls4.jpg\|left\|200px]]

-	The ~~entry 3ls4~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ls4", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ls4\| PDB=3ls4 \| SCENE= }}

-	~~Authors: Niemi, M.H., Rouvinen, J.~~	+	===Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC===

-	Description: Crystal Structure of Anti-tetrahydrocannabinol Fab Fragment in Complex with THC

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 17 09~~:11:30 2010''	+	==About this Structure==
		+	3LS4 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LS4 OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Niemi, M H.]]
		+	[[Category: Rouvinen, J.]]
		+	[[Category: Antibody]]
		+	[[Category: Cannabinoid complex]]
		+	[[Category: Fab fragment]]
		+	[[Category: Immune system]]
		+	[[Category: Immunoglobulin]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 2 08:39:07 2010''