3m8t - Revision history

OCA: Redirecting to 5wcm

OCA — Fri, 06 Oct 2017 05:40:15 GMT

Redirecting to 5wcm

←Older revision		Revision as of 05:40, 6 October 2017
Line 1:		Line 1:
-		+	#REDIRECT [[5wcm]] This PDB entry is obsolete and replaced by 5wcm
-	~~==Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide==~~	+
-	~~<StructureSection load='3m8t' size='340' side='right' caption='~~[[~~3m8t]], [[Resolution\|resolution]] 1.33Å' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[3m8t~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradu Bradu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M8T FirstGlance]. <br>	+
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NZ:4-NITROBENZENESULFONAMIDE'>4NZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lvz\|3lvz]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blr6230 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224911 BRADU])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m8t OCA], [http://pdbe.org/3m8t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m8t RCSB], [http://www.ebi.ac.uk/pdbsum/3m8t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m8t ProSAT]</span></td></tr>	+
-	~~</table>~~	+
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	~~Metallo-beta-lactamases (MBLs) are important enzymatic factors in resistance to beta-lactam antibiotics that show important structural~~ and ~~functional heterogeneity. BJP-1 is a subclass B3 MBL determinant produced~~ by Bradyrhizobium japonicum that exhibits interesting properties. BJP-1, like CAU-1 of Caulobacter vibrioides, overall poorly recognizes beta-lactam substrates and shows an unusual substrate profile compared to other MBLs. In order to understand the structural basis of these properties, the crystal structure of BJP-1 was obtained at 1.4-A resolution. This revealed significant differences in the conformation and locations of the active-site loops, determining a rather narrow active site and the presence of a unique N-terminal helix bearing Phe-31, whose side chain binds in the active site and represents an obstacle for beta-lactam substrate binding. In order to probe the potential of sulfonamides (known to inhibit various zinc-dependent enzymes) to bind in the active sites of MBLs, the structure of BJP-1 in complex with 4-nitrobenzenesulfonamide was also obtained (at 1.33-A resolution), thereby revealing the mode of interaction of these molecules in MBLs. Interestingly, sulfonamide binding resulted in the displacement of the side chain of Phe-31 from its hydrophobic binding pocket, where the benzene ring of the molecule is now found. These data further highlight the structural diversity shown by MBLs but also provide interesting insights in the structure-function relationships of these enzymes. More importantly, we provided the first structural observation of MBL interaction with sulfonamides, which might represent an interesting scaffold for the design of MBL inhibitors.	+
-		+
-	High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.,Docquier JD, Benvenuti M, Calderone V, Stoczko M, Menciassi N, Rossolini GM, Mangani S Antimicrob Agents Chemother. 2010 Oct;54(10):4343-51. Epub 2010 Aug 9. PMID:20696874<ref>PMID:20696874</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3m8t" style="background-color:#fffaf0;"></div>~~	+
-		+
-	~~==See Also==~~	+
-	*[[Beta-lactamase\|Beta-lactamase]]	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Beta-lactamase]]~~	+
-	~~[[Category: Bradu]]~~	+
-	~~[[Category: Benvenuti, M]]~~	+
-	~~[[Category: Calderone, V]]~~	+
-	~~[[Category: Docquier, J D]]~~	+
-	~~[[Category: Mangani, S]]~~	+
-	~~[[Category: Menciassi, N]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Subclass b3 beta-lactamase]]~~	+
-	~~[[Category: Sulfonamide complex]]~~	+
-	~~[[Category: Zinc enzyme]]~~	+

OCA at 04:05, 10 December 2016

OCA — Sat, 10 Dec 2016 04:05:13 GMT

←Older revision		Revision as of 04:05, 10 December 2016
Line 1:		Line 1:
		+
	==Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide==		==Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide==
	<StructureSection load='3m8t' size='340' side='right' caption='[[3m8t]], [[Resolution\|resolution]] 1.33Å' scene=''>		<StructureSection load='3m8t' size='340' side='right' caption='[[3m8t]], [[Resolution\|resolution]] 1.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bradyrhizobium_japonicum Bradyrhizobium japonicum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M8T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradu Bradu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M8T FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NZ:4-NITROBENZENESULFONAMIDE'>4NZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NZ:4-NITROBENZENESULFONAMIDE'>4NZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lvz\|3lvz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lvz\|3lvz]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blr6230 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~375 Bradyrhizobium japonicum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blr6230 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224911 BRADU])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m8t RCSB], [http://www.ebi.ac.uk/pdbsum/3m8t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m8t OCA], [http://pdbe.org/3m8t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3m8t RCSB], [http://www.ebi.ac.uk/pdbsum/3m8t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3m8t ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3m8t" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
-	[[Category: ~~Bradyrhizobium japonicum~~]]	+	[[Category: Bradu]]
	[[Category: Benvenuti, M]]		[[Category: Benvenuti, M]]
	[[Category: Calderone, V]]		[[Category: Calderone, V]]

OCA at 09:09, 9 December 2014

OCA — Tue, 09 Dec 2014 09:09:22 GMT

←Older revision		Revision as of 09:09, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3m8t.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide==
		+	<StructureSection load='3m8t' size='340' side='right' caption='[[3m8t]], [[Resolution\|resolution]] 1.33Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3M8T FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4NZ:4-NITROBENZENESULFONAMIDE'>4NZ</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3lvz\|3lvz]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blr6230 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=375 Bradyrhizobium japonicum])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3m8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m8t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3m8t RCSB], [http://www.ebi.ac.uk/pdbsum/3m8t PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Metallo-beta-lactamases (MBLs) are important enzymatic factors in resistance to beta-lactam antibiotics that show important structural and functional heterogeneity. BJP-1 is a subclass B3 MBL determinant produced by Bradyrhizobium japonicum that exhibits interesting properties. BJP-1, like CAU-1 of Caulobacter vibrioides, overall poorly recognizes beta-lactam substrates and shows an unusual substrate profile compared to other MBLs. In order to understand the structural basis of these properties, the crystal structure of BJP-1 was obtained at 1.4-A resolution. This revealed significant differences in the conformation and locations of the active-site loops, determining a rather narrow active site and the presence of a unique N-terminal helix bearing Phe-31, whose side chain binds in the active site and represents an obstacle for beta-lactam substrate binding. In order to probe the potential of sulfonamides (known to inhibit various zinc-dependent enzymes) to bind in the active sites of MBLs, the structure of BJP-1 in complex with 4-nitrobenzenesulfonamide was also obtained (at 1.33-A resolution), thereby revealing the mode of interaction of these molecules in MBLs. Interestingly, sulfonamide binding resulted in the displacement of the side chain of Phe-31 from its hydrophobic binding pocket, where the benzene ring of the molecule is now found. These data further highlight the structural diversity shown by MBLs but also provide interesting insights in the structure-function relationships of these enzymes. More importantly, we provided the first structural observation of MBL interaction with sulfonamides, which might represent an interesting scaffold for the design of MBL inhibitors.

-	~~{{STRUCTURE_3m8t\| PDB=3m8t \| SCENE= }}~~	+	High-resolution crystal structure of the subclass B3 metallo-beta-lactamase BJP-1: rational basis for substrate specificity and interaction with sulfonamides.,Docquier JD, Benvenuti M, Calderone V, Stoczko M, Menciassi N, Rossolini GM, Mangani S Antimicrob Agents Chemother. 2010 Oct;54(10):4343-51. Epub 2010 Aug 9. PMID:20696874<ref>PMID:20696874</ref>

-	~~===Crystal Structure~~ of the ~~complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20696874}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3m8t]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].~~	+

	==See Also==		==See Also==
	*[[Beta-lactamase\|Beta-lactamase]]		*[[Beta-lactamase\|Beta-lactamase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020696874<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Bradyrhizobium japonicum]]		[[Category: Bradyrhizobium japonicum]]
-	[[Category: Benvenuti, M.]]	+	[[Category: Benvenuti, M]]
-	[[Category: Calderone, V.]]	+	[[Category: Calderone, V]]
-	[[Category: Docquier, J D.]]	+	[[Category: Docquier, J D]]
-	[[Category: Mangani, S.]]	+	[[Category: Mangani, S]]
-	[[Category: Menciassi, N.]]	+	[[Category: Menciassi, N]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Subclass b3 beta-lactamase]]		[[Category: Subclass b3 beta-lactamase]]
	[[Category: Sulfonamide complex]]		[[Category: Sulfonamide complex]]
	[[Category: Zinc enzyme]]		[[Category: Zinc enzyme]]

OCA at 21:37, 20 October 2012

OCA — Sat, 20 Oct 2012 21:37:03 GMT

←Older revision		Revision as of 21:37, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3m8t]] is a 2 chain structure ~~of [[Beta-lactamase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].	+	[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].

	==See Also==		==See Also==

OCA at 13:46, 27 July 2012

OCA — Fri, 27 Jul 2012 13:46:38 GMT

←Older revision		Revision as of 13:46, 27 July 2012
Line 1:		Line 1:
-	[[Image:3m8t.~~jpg~~\|left\|200px]]	+	[[Image:3m8t.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3m8t", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3m8t\| PDB=3m8t \| SCENE= }}		{{STRUCTURE_3m8t\| PDB=3m8t \| SCENE= }}

	===Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide===		===Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20696874}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20696874 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20696874}}		{{ABSTRACT_PUBMED_20696874}}

	==About this Structure==		==About this Structure==
-	[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].	+	[[3m8t]] is a 2 chain structure of [[Beta-lactamase]] with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].
		+
		+	==See Also==
		+	*[[Beta-lactamase\|Beta-lactamase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20696874~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020696874</ref><references group="xtra"/>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Bradyrhizobium japonicum]]		[[Category: Bradyrhizobium japonicum]]
Line 30:		Line 22:
	[[Category: Mangani, S.]]		[[Category: Mangani, S.]]
	[[Category: Menciassi, N.]]		[[Category: Menciassi, N.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Subclass b3 beta-lactamase]]
		+	[[Category: Sulfonamide complex]]
		+	[[Category: Zinc enzyme]]

OCA: Protected "3m8t" [edit=sysop:move=sysop]

OCA — Wed, 12 Jan 2011 05:14:29 GMT

Protected "3m8t" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:14, 12 January 2011

OCA at 05:14, 12 January 2011

OCA — Wed, 12 Jan 2011 05:14:26 GMT

←Older revision		Revision as of 05:14, 12 January 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3m8t.jpg\|left\|200px]]

-	The ~~entry 3m8t~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3m8t", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3m8t\| PDB=3m8t \| SCENE= }}

-	~~Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S.~~	+	===Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide===

-	Description: Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed May 5 11~~:38:~~08 2010''~~	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20696874}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20696874 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20696874}}
		+
		+	==About this Structure==
		+	[[3m8t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bradyrhizobium_japonicum Bradyrhizobium japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8T OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20696874</ref><references group="xtra"/>
		+	[[Category: Beta-lactamase]]
		+	[[Category: Bradyrhizobium japonicum]]
		+	[[Category: Benvenuti, M.]]
		+	[[Category: Calderone, V.]]
		+	[[Category: Docquier, J D.]]
		+	[[Category: Mangani, S.]]
		+	[[Category: Menciassi, N.]]

OCA at 08:38, 5 May 2010

OCA — Wed, 05 May 2010 08:38:09 GMT

←Older revision		Revision as of 08:38, 5 May 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3m8t is ON HOLD	+	The entry 3m8t is ON HOLD until Paper Publication

	Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S.		Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S.
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	Description: Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide		Description: Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Mar 31 13~~:23:14 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:38:08 2010''

OCA: New page: '''Unreleased structure''' The entry 3m8t is ON HOLD Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S. Description: Crystal Structure of the complex bet...

OCA — Wed, 31 Mar 2010 10:23:15 GMT

New page: '''Unreleased structure''' The entry 3m8t is ON HOLD Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S. Description: Crystal Structure of the complex bet...

New page

'''Unreleased structure'''

The entry 3m8t is ON HOLD

Authors: Docquier, J.D., Benvenuti, M., Calderone, V., Menciassi, N., Mangani, S.

Description: Crystal Structure of the complex between class B3 beta-lactamase BJP-1 and 4-nitrobenzene-sulfonamide

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:23:14 2010''