3mc0 - Revision history

OCA at 08:51, 6 September 2023

OCA — Wed, 06 Sep 2023 08:51:22 GMT

←Older revision		Revision as of 08:51, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3mc0' size='340' side='right'caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3mc0' size='340' side='right'caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885~~] and [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [https://pdbe.org/3mc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [https://pdbe.org/3mc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A2NTY6_MOUSE A2NTY6_MOUSE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Cho, S]]	+	[[Category: Staphylococcus aureus]]
-	[[Category: Fernandez~~, M M~~]]	+	[[Category: Cho S]]
-	[[Category: Malchiodi~~, E L~~]]	+	[[Category: Fernandez MM]]
-	[[Category: Mariuzza~~, R A~~]]	+	[[Category: Malchiodi EL]]
-	[[Category: Robinson, H]]	+	[[Category: Mariuzza RA]]
-	~~[[Category: Exotoxin]]~~	+	[[Category: Robinson H]]
-	~~[[Category: Immune system~~]]	+

OCA at 07:33, 20 July 2022

OCA — Wed, 20 Jul 2022 07:33:39 GMT

←Older revision		Revision as of 07:33, 20 July 2022
Line 3:		Line 3:
	<StructureSection load='3mc0' size='340' side='right'caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3mc0' size='340' side='right'caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [~~http~~://pdbe.org/3mc0 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [https://pdbe.org/3mc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:40, 14 October 2020

OCA — Wed, 14 Oct 2020 06:40:41 GMT

←Older revision		Revision as of 06:40, 14 October 2020
Line 1:		Line 1:

	==Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain==		==Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain==
-	<StructureSection load='3mc0' size='340' side='right' caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3mc0' size='340' side='right'caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://pdbe.org/3mc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://pdbe.org/3mc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[T-cell receptor\|T-cell receptor]]	+	*[[T-cell receptor 3D structures\|T-cell receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Cho, S]]		[[Category: Cho, S]]

OCA at 02:13, 5 August 2016

OCA — Fri, 05 Aug 2016 02:13:29 GMT

←Older revision		Revision as of 02:13, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain==		==Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain==
	<StructureSection load='3mc0' size='340' side='right' caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3mc0' size='340' side='right' caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~] and [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus Staphylococcus aureus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://pdbe.org/3mc0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mc0 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mc0" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 22:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus]]~~	+	[[Category: Lk3 transgenic mice]]
-	~~[[Category: Staphylococcus aureus~~]]	+
	[[Category: Cho, S]]		[[Category: Cho, S]]
	[[Category: Fernandez, M M]]		[[Category: Fernandez, M M]]

OCA at 23:15, 3 January 2015

OCA — Sat, 03 Jan 2015 23:15:25 GMT

←Older revision		Revision as of 23:15, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 13:
	Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.,Fernandez MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL J Biol Chem. 2011 Jan 14;286(2):1189-95. Epub 2010 Nov 8. PMID:21059660<ref>PMID:21059660</ref>		Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.,Fernandez MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL J Biol Chem. 2011 Jan 14;286(2):1189-95. Epub 2010 Nov 8. PMID:21059660<ref>PMID:21059660</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[T-cell receptor\|T-cell receptor]]
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 24:
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
-	[[Category: Cho, S.]]	+	[[Category: Cho, S]]
-	[[Category: Fernandez, M M.]]	+	[[Category: Fernandez, M M]]
-	[[Category: Malchiodi, E L.]]	+	[[Category: Malchiodi, E L]]
-	[[Category: Mariuzza, R A.]]	+	[[Category: Mariuzza, R A]]
-	[[Category: Robinson, H.]]	+	[[Category: Robinson, H]]
	[[Category: Exotoxin]]		[[Category: Exotoxin]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 10:35, 28 May 2014

OCA — Wed, 28 May 2014 10:35:23 GMT

←Older revision		Revision as of 10:35, 28 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3mc0.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain==
		+	<StructureSection load='3mc0' size='340' side='right' caption='[[3mc0]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MC0 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1xxg\|1xxg]], [[2aq3\|2aq3]], [[3owe\|3owe]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mc0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mc0 RCSB], [http://www.ebi.ac.uk/pdbsum/3mc0 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Superantigens (SAgs) are bacterial or viral toxins that bind MHC class II (MHC-II) molecules and T-cell receptor (TCR) in a nonconventional manner, inducing T-cell activation that leads to inflammatory cytokine production, which may result in acute toxic shock. In addition, the emerging threat of purpura fulminans and community-associated meticillin-resistant Staphylococcus aureus emphasizes the importance of a better characterization of SAg binding to their natural ligands that may allow the development of reagents to neutralize their action. The three-dimensional structure of the complex between a mouse TCR beta chain (mVbeta8.2) and staphylococcal enterotoxin G (SEG) at 2.0 A resolution revealed a binding site that does not conserve the "hot spots" present in mVbeta8.2-SEC2, mVbeta8.2-SEC3, mVbeta8.2-SEB, and mVbeta8.2-SPEA complexes. Analysis of the mVbeta8.2-SEG interface allowed us to explain the higher affinity of this complex compared with the others, which may account for the early activation of T-cells bearing mVbeta8.2 by SEG. This mode of interaction between SEG and mVbeta8.2 could be an adaptive advantage to bestow on the pathogen a faster rate of colonization of the host.

-	~~<!-~~-	+	Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.,Fernandez MM, Cho S, De Marzi MC, Kerzic MC, Robinson H, Mariuzza RA, Malchiodi EL J Biol Chem. 2011 Jan 14;286(2):1189-95. Epub 2010 Nov 8. PMID:21059660<ref>PMID:21059660</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3mc0"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3mc0\| PDB=3mc0 \| SCENE= }}~~	+

-	~~===Crystal Structure~~ of ~~Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21059660}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21059660 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21059660}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3mc0]] is a 4 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021059660<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]

OCA at 06:50, 18 April 2012

OCA — Wed, 18 Apr 2012 06:50:53 GMT

←Older revision		Revision as of 06:50, 18 April 2012
Line 22:		Line 22:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21059660~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021059660</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
Line 30:		Line 30:
	[[Category: Mariuzza, R A.]]		[[Category: Mariuzza, R A.]]
	[[Category: Robinson, H.]]		[[Category: Robinson, H.]]
		+	[[Category: Exotoxin]]
		+	[[Category: Immune system]]

OCA: Protected "3mc0" [edit=sysop:move=sysop]

OCA — Wed, 23 Feb 2011 09:20:19 GMT

Protected "3mc0" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:20, 23 February 2011

OCA at 09:20, 23 February 2011

OCA — Wed, 23 Feb 2011 09:20:17 GMT

←Older revision		Revision as of 09:20, 23 February 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3mc0.png\|left\|200px]]
-	[[Image:3mc0.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 12:		Line 11:
	===Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain===		===Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21059660}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21059660 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21059660}}

	==About this Structure==		==About this Structure==
-	~~3MC0~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA].	+	[[3mc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21059660</ref><references group="xtra"/>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Staphylococcus aureus]]		[[Category: Staphylococcus aureus]]
Line 22:		Line 30:
	[[Category: Mariuzza, R A.]]		[[Category: Mariuzza, R A.]]
	[[Category: Robinson, H.]]		[[Category: Robinson, H.]]
-	[[Category: Exotoxin]]
-	[[Category: Immune system]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:47:42 2010''

OCA at 07:37, 13 October 2010

OCA — Wed, 13 Oct 2010 07:37:54 GMT

←Older revision		Revision as of 07:37, 13 October 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3mc0.jpg\|left\|200px]]

-	The ~~entry 3mc0~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3mc0", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3mc0\| PDB=3mc0 \| SCENE= }}

-	~~Authors: Cho, S., Fernandez, M.M., Mariuzza, R.A., Malchiodi, E.L.~~	+	===Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain===

-	Description: Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a Mouse T-cell Receptor beta Chain

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 15~~ 10:32:14 2010''	+	==About this Structure==
		+	3MC0 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC0 OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Staphylococcus aureus]]
		+	[[Category: Cho, S.]]
		+	[[Category: Fernandez, M M.]]
		+	[[Category: Malchiodi, E L.]]
		+	[[Category: Mariuzza, R A.]]
		+	[[Category: Robinson, H.]]
		+	[[Category: Exotoxin]]
		+	[[Category: Immune system]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:47:42 2010''