3mkm - Revision history

OCA at 16:35, 1 November 2023

OCA — Wed, 01 Nov 2023 16:35:07 GMT

←Older revision		Revision as of 16:35, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3mkm' size='340' side='right'caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3mkm' size='340' side='right'caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MKM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MKM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max~~-~~height: 3em;'>[[1q8f\|1q8f]]~~, [[~~3b9x~~\|~~3b9x~~]]~~, [[3mkn\|3mkn]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>YeiK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~83333 ECOLI])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [https://pdbe.org/3mkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [https://www.ebi.ac.uk/pdbsum/3mkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [https://pdbe.org/3mkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [https://www.ebi.ac.uk/pdbsum/3mkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/C3T3U2_ECOLX C3T3U2_ECOLX]] Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides (By similarity).[HAMAP-Rule:MF_01433]	+	[https://www.uniprot.org/uniprot/C3T3U2_ECOLX C3T3U2_ECOLX] Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides (By similarity).[HAMAP-Rule:MF_01433]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Ribosylpyrimidine nucleosidase]]~~	+	[[Category: Degano M]]
-	[[Category: Degano, M]]	+	[[Category: Fornili A]]
-	[[Category: Fornili, A]]	+	[[Category: Garau G]]
-	[[Category: Garau, G]]	+	[[Category: Giabbai B]]
-	[[Category: Giabbai, B]]	+
-	~~[[Category: Bacterial nucleosidase]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Metalloenzyme]]~~	+
-	~~[[Category: Nucleotide metabolism]]~~	+
-	~~[[Category: Pyrimidine nucleoside hydrolase~~]]	+

OCA at 13:47, 4 May 2022

OCA — Wed, 04 May 2022 13:47:47 GMT

←Older revision		Revision as of 13:47, 4 May 2022
Line 1:		Line 1:

	==Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)==		==Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)==
-	<StructureSection load='3mkm' size='340' side='right' caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='3mkm' size='340' side='right'caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MKM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MKM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1q8f\|1q8f]], [[3b9x\|3b9x]], [[3mkn\|3mkn]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1q8f\|1q8f]], [[3b9x\|3b9x]], [[3mkn\|3mkn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YeiK ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YeiK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [~~http~~://pdbe.org/3mkm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mkm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [https://pdbe.org/3mkm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [https://www.ebi.ac.uk/pdbsum/3mkm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/C3T3U2_ECOLX C3T3U2_ECOLX]] Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides (By similarity).[HAMAP-Rule:MF_01433]	+	[[https://www.uniprot.org/uniprot/C3T3U2_ECOLX C3T3U2_ECOLX]] Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides (By similarity).[HAMAP-Rule:MF_01433]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Ribosylpyrimidine nucleosidase]]		[[Category: Ribosylpyrimidine nucleosidase]]
	[[Category: Degano, M]]		[[Category: Degano, M]]

OCA at 19:04, 5 August 2016

OCA — Fri, 05 Aug 2016 19:04:55 GMT

←Older revision		Revision as of 19:04, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)==		==Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)==
	<StructureSection load='3mkm' size='340' side='right' caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3mkm' size='340' side='right' caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MKM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MKM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1q8f\|1q8f]], [[3b9x\|3b9x]], [[3mkn\|3mkn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1q8f\|1q8f]], [[3b9x\|3b9x]], [[3mkn\|3mkn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YeiK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~562 Escherichia coli~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YeiK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [http://www.ebi.ac.uk/pdbsum/3mkm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [http://pdbe.org/3mkm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [http://www.ebi.ac.uk/pdbsum/3mkm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mkm" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia coli~~]]	+	[[Category: Ecoli]]
	[[Category: Ribosylpyrimidine nucleosidase]]		[[Category: Ribosylpyrimidine nucleosidase]]
	[[Category: Degano, M]]		[[Category: Degano, M]]

OCA at 05:03, 25 December 2014

OCA — Thu, 25 Dec 2014 05:03:56 GMT

←Older revision		Revision as of 05:03, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [http://www.ebi.ac.uk/pdbsum/3mkm PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [http://www.ebi.ac.uk/pdbsum/3mkm PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/C3T3U2_ECOLX C3T3U2_ECOLX]] Hydrolyzes cytidine or uridine to ribose and cytosine or uracil, respectively. Has a clear preference for cytidine over uridine. Strictly specific for ribonucleosides (By similarity).[HAMAP-Rule:MF_01433]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:24, 18 December 2014

OCA — Thu, 18 Dec 2014 15:24:32 GMT

←Older revision		Revision as of 15:24, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3mkm\| PDB=3mkm \| SCENE= }}~~	+	==Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)==
-	===Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)===	+	<StructureSection load='3mkm' size='340' side='right' caption='[[3mkm]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21082835}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mkm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MKM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1q8f\|1q8f]], [[3b9x\|3b9x]], [[3mkn\|3mkn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YeiK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribosylpyrimidine_nucleosidase Ribosylpyrimidine nucleosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.8 3.2.2.8] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mkm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mkm RCSB], [http://www.ebi.ac.uk/pdbsum/3mkm PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Conformational changes modulate macromolecular function by promoting the specific binding of ligands (such as in antigen recognition) or the stabilization of transition states in enzymatic reactions. However, quantitative characterization of the energetics underlying dynamic structural interconversions is still challenging and lacks a unified method. Here, we introduce a novel in silico approach based on the combined use of essential dynamics sampling and nonequilibrium free-energy calculations to obtain quantitative data on conformational energy landscapes. This technique allows the unbiased investigation of highly complex rearrangements, and does not require the crucial definition of user-defined collective variables. We show that free-energy values derived from profiles connecting the unliganded and ligand-bound X-ray structures of a bacterial nucleoside hydrolase match the experimental binding constant. This approach also provides first evidence for a rate-limiting character of the conformational transition in this enzyme, and an unexpected role of the protonation state of a single residue in regulating substrate binding and product release.

-	~~==About this Structure==~~	+	Energy Landscapes Associated with Macromolecular Conformational Changes from Endpoint Structures.,Fornili A, Giabbai B, Garau G, Degano M J Am Chem Soc. 2010 Nov 17. PMID:21082835<ref>PMID:21082835</ref>
-	~~[[3mkm]] is a 4 chain structure~~ with ~~sequence~~ from ~~[http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA].~~	+

-	~~==Reference==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:021082835<~~/~~ref>~~<~~ref group="xtra"~~>~~PMID:015130467~~</~~ref~~>~~<ref group~~=~~"xtra">PMID:016411753</ref><ref group~~=~~"xtra">PMID:009572842</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ribosylpyrimidine nucleosidase]]		[[Category: Ribosylpyrimidine nucleosidase]]
-	[[Category: Degano, M.]]	+	[[Category: Degano, M]]
-	[[Category: Fornili, A.]]	+	[[Category: Fornili, A]]
-	[[Category: Garau, G.]]	+	[[Category: Garau, G]]
-	[[Category: Giabbai, B.]]	+	[[Category: Giabbai, B]]
	[[Category: Bacterial nucleosidase]]		[[Category: Bacterial nucleosidase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 20:54, 17 April 2013

OCA — Wed, 17 Apr 2013 20:54:46 GMT

←Older revision		Revision as of 20:54, 17 April 2013
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-	[[Image:3mkm.png\|left\|200px]]
-
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	{{STRUCTURE_3mkm\| PDB=3mkm \| SCENE= }}		{{STRUCTURE_3mkm\| PDB=3mkm \| SCENE= }}
-
	===Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)===		===Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)===
-
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	{{ABSTRACT_PUBMED_21082835}}		{{ABSTRACT_PUBMED_21082835}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21082835~~</ref><ref group="xtra">PMID:~~15130467~~</ref><ref group="xtra">PMID:~~16411753~~</ref><ref group="xtra">PMID:~~9572842~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021082835</ref><ref group="xtra">PMID:015130467</ref><ref group="xtra">PMID:016411753</ref><ref group="xtra">PMID:009572842</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Ribosylpyrimidine nucleosidase]]		[[Category: Ribosylpyrimidine nucleosidase]]

OCA: Protected "3mkm" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:56:03 GMT

Protected "3mkm" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:56, 14 March 2011

OCA at 18:56, 14 March 2011

OCA — Mon, 14 Mar 2011 18:56:01 GMT

←Older revision		Revision as of 18:56, 14 March 2011
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-	{{Seed}}
	[[Image:3mkm.png\|left\|200px]]		[[Image:3mkm.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	~~3MKM~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA].	+	[[3mkm]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA].

	==Reference==		==Reference==
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	[[Category: Nucleotide metabolism]]		[[Category: Nucleotide metabolism]]
	[[Category: Pyrimidine nucleoside hydrolase]]		[[Category: Pyrimidine nucleoside hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:43 2010''

OCA at 06:12, 22 December 2010

OCA — Wed, 22 Dec 2010 06:12:07 GMT

←Older revision		Revision as of 06:12, 22 December 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3mkm.~~jpg~~\|left\|200px]]	+	[[Image:3mkm.png\|left\|200px]]

	<!--		<!--
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	[[Category: Pyrimidine nucleoside hydrolase]]		[[Category: Pyrimidine nucleoside hydrolase]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec ~~1 11~~:30:57 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:24:43 2010''

OCA at 08:19, 1 December 2010

OCA — Wed, 01 Dec 2010 08:19:10 GMT

←Older revision		Revision as of 08:19, 1 December 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3mkm.jpg\|left\|200px]]

-	The ~~entry 3mkm~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3mkm", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3mkm\| PDB=3mkm \| SCENE= }}

-	~~Authors: Garau, G., Fornili, A., Giabbai, B., Degano, M~~.	+	===Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)===

-	Description: Crystal structure of the E. coli pyrimidine nucleoside hydrolase YeiK (Apo-form)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 23 08~~:41:48 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21082835}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21082835 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21082835}}
		+
		+	==About this Structure==
		+	3MKM is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKM OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21082835</ref><ref group="xtra">PMID:15130467</ref><ref group="xtra">PMID:16411753</ref><ref group="xtra">PMID:9572842</ref><references group="xtra"/>
		+	[[Category: Escherichia coli]]
		+	[[Category: Ribosylpyrimidine nucleosidase]]
		+	[[Category: Degano, M.]]
		+	[[Category: Fornili, A.]]
		+	[[Category: Garau, G.]]
		+	[[Category: Giabbai, B.]]
		+	[[Category: Bacterial nucleosidase]]
		+	[[Category: Hydrolase]]
		+	[[Category: Metalloenzyme]]
		+	[[Category: Nucleotide metabolism]]
		+	[[Category: Pyrimidine nucleoside hydrolase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:30:57 2010''