3mw3 - Revision history

OCA at 09:02, 6 September 2023

OCA — Wed, 06 Sep 2023 09:02:43 GMT

←Older revision		Revision as of 09:02, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3mw3' size='340' side='right'caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>		<StructureSection load='3mw3' size='340' side='right'caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Buffalo_rat Buffalo rat~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BMA:BETA~~-~~D-MANNOSE'>BMA</scene>~~, ~~<scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.33Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3mw2\|3mw2]], [[3mw4\|3mw4]]~~</~~div~~><~~/td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">Nrxn2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [https://pdbe.org/3mw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [https://pdbe.org/3mw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/NRX2B_RAT NRX2B_RAT] Neuronal cell surface protein that may be involved in cell recognition and cell adhesion.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Buffalo rat]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Jin, X~~]]	+	[[Category: Rattus norvegicus]]
-	[[Category: ~~Shapiro, L~~]]	+	[[Category: Jin X]]
-	[[Category: ~~Calcium-binding]]~~	+	[[Category: Shapiro L]]
-	~~[[Category: Cell adhesion]]~~	+
-	~~[[Category: Glycoprotein]]~~	+
-	~~[[Category: Lns domain]]~~	+
-	~~[[Category: Neurexin~~]]	+

OCA at 05:43, 6 October 2021

OCA — Wed, 06 Oct 2021 05:43:04 GMT

←Older revision		Revision as of 05:43, 6 October 2021
Line 1:		Line 1:

	==Crystal structure of beta-neurexin 2 with the splice insert 4==		==Crystal structure of beta-neurexin 2 with the splice insert 4==
-	<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>	+	<StructureSection load='3mw3' size='340' side='right'caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3mw2\|3mw2]], [[3mw4\|3mw4]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Nrxn2 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Nrxn2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [~~http~~://pdbe.org/3mw3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [https://pdbe.org/3mw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [https://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/3mw3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/3mw3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3mw3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3mw3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Neurexin\|Neurexin]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Buffalo rat]]		[[Category: Buffalo rat]]
		+	[[Category: Large Structures]]
	[[Category: Jin, X]]		[[Category: Jin, X]]
	[[Category: Shapiro, L]]		[[Category: Shapiro, L]]

OCA at 08:18, 8 November 2017

OCA — Wed, 08 Nov 2017 08:18:52 GMT

←Older revision		Revision as of 08:18, 8 November 2017
Line 3:		Line 3:
	<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>		<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Nrxn2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Buffalo rat])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [http://pdbe.org/3mw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [http://pdbe.org/3mw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>
	</table>		</table>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3mw3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3mw3" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Neurexin\|Neurexin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Buffalo rat]]
	[[Category: Jin, X]]		[[Category: Jin, X]]
	[[Category: Shapiro, L]]		[[Category: Shapiro, L]]

OCA at 04:00, 10 December 2016

OCA — Sat, 10 Dec 2016 04:00:52 GMT

←Older revision		Revision as of 04:00, 10 December 2016
Line 1:		Line 1:
		+
	==Crystal structure of beta-neurexin 2 with the splice insert 4==		==Crystal structure of beta-neurexin 2 with the splice insert 4==
	<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>		<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Nrxn2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [http://pdbe.org/3mw3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mw3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3mw3 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mw3 PDBsum]</span></td></tr>	+
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mw3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3mw3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Rattus norvegicus]]
	[[Category: Jin, X]]		[[Category: Jin, X]]
	[[Category: Shapiro, L]]		[[Category: Shapiro, L]]

OCA at 08:56, 9 December 2014

OCA — Tue, 09 Dec 2014 08:56:16 GMT

←Older revision		Revision as of 08:56, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3mw3.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of beta-neurexin 2 with the splice insert 4==
		+	<StructureSection load='3mw3' size='340' side='right' caption='[[3mw3]], [[Resolution\|resolution]] 2.33Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3mw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3MW3 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mw2\|3mw2]], [[3mw4\|3mw4]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Nrxn2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3mw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mw3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3mw3 RCSB], [http://www.ebi.ac.uk/pdbsum/3mw3 PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mw/3mw3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Alternatively spliced beta-neurexins (beta-NRXs) and neuroligins (NLs) are thought to have distinct extracellular binding affinities, potentially providing a beta-NRX/NL synaptic recognition code. We utilized surface plasmon resonance to measure binding affinities between all combinations of alternatively spliced beta-NRX 1-3 and NL 1-3 ectodomains. Binding was observed for all beta-NRX/NL pairs. The presence of the NL1 B splice insertion lowers beta-NRX binding affinity by approximately 2-fold, while beta-NRX splice insertion 4 has small effects that do not synergize with NL splicing. New structures of glycosylated beta-NRXs 1 and 2 containing splice insertion 4 reveal that the insertion forms a new beta strand that replaces the beta10 strand, leaving the NL binding site intact. This helps to explain the limited effect of splice insert 4 on NRX/NL binding affinities. These results provide new structural insights and quantitative binding information to help determine whether and how splice isoform choice plays a role in beta-NRX/NL-mediated synaptic recognition.

-	~~{{STRUCTURE_3mw3\| PDB=3mw3 \| SCENE= }}~~	+	Splice form dependence of beta-neurexin/neuroligin binding interactions.,Koehnke J, Katsamba PS, Ahlsen G, Bahna F, Vendome J, Honig B, Shapiro L, Jin X Neuron. 2010 Jul 15;67(1):61-74. PMID:20624592<ref>PMID:20624592</ref>

-	~~===Crystal structure~~ of ~~beta-neurexin 2 with~~ the ~~splice insert 4===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20624592}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3mw3]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_norvegicus Rattus norvegicus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].~~	+

	==See Also==		==See Also==
	*[[Neurexin\|Neurexin]]		*[[Neurexin\|Neurexin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020624592<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Jin, X.]]	+	[[Category: Jin, X]]
-	[[Category: Shapiro, L.]]	+	[[Category: Shapiro, L]]
	[[Category: Calcium-binding]]		[[Category: Calcium-binding]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 09:06, 20 October 2012

OCA — Sat, 20 Oct 2012 09:06:40 GMT

←Older revision		Revision as of 09:06, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3mw3]] is a 1 chain structure ~~of [[Neurexin]]~~ with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].	+	[[3mw3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].

	==See Also==		==See Also==

OCA at 21:47, 25 July 2012

OCA — Wed, 25 Jul 2012 21:47:30 GMT

←Older revision		Revision as of 21:47, 25 July 2012
Line 1:		Line 1:
	[[Image:3mw3.png\|left\|200px]]		[[Image:3mw3.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3mw3", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3mw3\| PDB=3mw3 \| SCENE= }}		{{STRUCTURE_3mw3\| PDB=3mw3 \| SCENE= }}

	===Crystal structure of beta-neurexin 2 with the splice insert 4===		===Crystal structure of beta-neurexin 2 with the splice insert 4===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20624592}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20624592 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20624592}}		{{ABSTRACT_PUBMED_20624592}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Neurexin]]	+	*[[Neurexin\|Neurexin]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20624592~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020624592</ref><references group="xtra"/>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Jin, X.]]		[[Category: Jin, X.]]

OCA: Protected "3mw3" [edit=sysop:move=sysop]

OCA — Mon, 27 Dec 2010 02:27:42 GMT

Protected "3mw3" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:27, 27 December 2010

OCA at 02:27, 27 December 2010

OCA — Mon, 27 Dec 2010 02:27:40 GMT

←Older revision		Revision as of 02:27, 27 December 2010
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3mw3.png\|left\|200px]]
-	[[Image:3mw3.~~jpg~~\|left\|200px]]	+

	<!--		<!--
Line 20:		Line 19:

	==About this Structure==		==About this Structure==
-	~~3MW3~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].	+	[[3mw3]] is a 1 chain structure of [[Neurexin]] with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].
		+
		+	==See Also==
		+	*[[Neurexin]]

	==Reference==		==Reference==
Line 32:		Line 34:
	[[Category: Lns domain]]		[[Category: Lns domain]]
	[[Category: Neurexin]]		[[Category: Neurexin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:40:02 2010''

OCA at 08:33, 28 July 2010

OCA — Wed, 28 Jul 2010 08:33:20 GMT

←Older revision		Revision as of 08:33, 28 July 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3mw3.jpg\|left\|200px]]

-	The ~~entry 3mw3~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3mw3", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3mw3\| PDB=3mw3 \| SCENE= }}

-	~~Authors: Jin, X., Shapiro, L.~~	+	===Crystal structure of beta-neurexin 2 with the splice insert 4===

-	Description: Crystal structure of beta-neurexin 2 with the splice insert 4

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu May 20 09~~:18:46 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20624592}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20624592 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20624592}}
		+
		+	==About this Structure==
		+	3MW3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MW3 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20624592</ref><references group="xtra"/>
		+	[[Category: Rattus norvegicus]]
		+	[[Category: Jin, X.]]
		+	[[Category: Shapiro, L.]]
		+	[[Category: Calcium-binding]]
		+	[[Category: Cell adhesion]]
		+	[[Category: Glycoprotein]]
		+	[[Category: Lns domain]]
		+	[[Category: Neurexin]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:40:02 2010''