3nam - Revision history

OCA at 16:45, 1 November 2023

OCA — Wed, 01 Nov 2023 16:45:06 GMT

←Older revision		Revision as of 16:45, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3nam' size='340' side='right'caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='3nam' size='340' side='right'caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nam]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NAM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nam]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NAM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OTK:(3S,3AR,4S,6S,6AS,8R,9R,9AR,9BS)-6-(ACETYLOXY)-4-(BUTANOYLOXY)-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-2-OXODODECAHYDROAZULENO[4,5-B]FURAN-8-YL+(2Z)-2-METHYLBUT-2-ENOATE'>OTK</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.1Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2by4\|2by4]], [[2c8k\|2c8k]], [[3nal\|3nal]], [[3nan\|3nan]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OTK:(3S,3AR,4S,6S,6AS,8R,9R,9AR,9BS)-6-(ACETYLOXY)-4-(BUTANOYLOXY)-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-2-OXODODECAHYDROAZULENO[4,5-B]FURAN-8-YL+(2Z)-2-METHYLBUT-2-ENOATE'>OTK</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nam OCA], [https://pdbe.org/3nam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nam RCSB], [https://www.ebi.ac.uk/pdbsum/3nam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nam ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nam OCA], [~~http~~://pdbe.org/3nam PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nam RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nam PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nam ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B6CAM1_RABIT B6CAM1_RABIT]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Calcium-transporting ATPase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Oryctolagus cuniculus]]		[[Category: Oryctolagus cuniculus]]
-	[[Category: Moller~~, J V~~]]	+	[[Category: Moller JV]]
-	[[Category: Nissen, P]]	+	[[Category: Nissen P]]
-	[[Category: Olesen, C]]	+	[[Category: Olesen C]]
-	[[Category: Sonntag, Y]]	+	[[Category: Sonntag Y]]
-	[[Category: Winther~~, A M.L]]~~	+	[[Category: Winther AML]]
-	~~[[Category: Ca2+-atpase]]~~	+
-	~~[[Category: Calcium transport]]~~	+
-	~~[[Category: Endoplasmic reticulum]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ion transport]]~~	+
-	~~[[Category: P-type atpase]]~~	+
-	~~[[Category: Prostate cancer]]~~	+
-	~~[[Category: Sarcoplasmic reticulum]]~~	+
-	~~[[Category: Serca]]~~	+
-	~~[[Category: Thapsigargin]]~~	+
-	~~[[Category: Transmembrane]]~~	+
-	~~[[Category: Transport~~]]	+

OCA at 17:53, 14 August 2019

OCA — Wed, 14 Aug 2019 17:53:51 GMT

←Older revision		Revision as of 17:53, 14 August 2019
Line 1:		Line 1:

	==SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg==		==SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg==
-	<StructureSection load='3nam' size='340' side='right' caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>	+	<StructureSection load='3nam' size='340' side='right'caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3nam]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAM FirstGlance]. <br>		<table><tr><td colspan='2'>[[3nam]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAM FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nam_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nam_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3nam" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3nam" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Calcium-transporting ATPase]]		[[Category: Calcium-transporting ATPase]]
		+	[[Category: Large Structures]]
	[[Category: Oryctolagus cuniculus]]		[[Category: Oryctolagus cuniculus]]
	[[Category: Moller, J V]]		[[Category: Moller, J V]]

OCA at 08:26, 8 November 2017

OCA — Wed, 08 Nov 2017 08:26:47 GMT

←Older revision		Revision as of 08:26, 8 November 2017
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 3nam" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3nam" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[ATPase\|ATPase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:04, 10 December 2016

OCA — Sat, 10 Dec 2016 04:04:20 GMT

←Older revision		Revision as of 04:04, 10 December 2016
Line 1:		Line 1:
		+
	==SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg==		==SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg==
	<StructureSection load='3nam' size='340' side='right' caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>		<StructureSection load='3nam' size='340' side='right' caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2by4\|2by4]], [[2c8k\|2c8k]], [[3nal\|3nal]], [[3nan\|3nan]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2by4\|2by4]], [[2c8k\|2c8k]], [[3nal\|3nal]], [[3nan\|3nan]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nam OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nam RCSB], [http://www.ebi.ac.uk/pdbsum/3nam PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nam OCA], [http://pdbe.org/3nam PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nam RCSB], [http://www.ebi.ac.uk/pdbsum/3nam PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nam ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nam ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nam" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:06, 9 December 2014

OCA — Tue, 09 Dec 2014 09:06:52 GMT

←Older revision		Revision as of 09:06, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3nam.~~png~~\|~~left~~\|200px]]	+	==SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg==
		+	<StructureSection load='3nam' size='340' side='right' caption='[[3nam]], [[Resolution\|resolution]] 3.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nam]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAM FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=OTK:(3S,3AR,4S,6S,6AS,8R,9R,9AR,9BS)-6-(ACETYLOXY)-4-(BUTANOYLOXY)-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-2-OXODODECAHYDROAZULENO[4,5-B]FURAN-8-YL+(2Z)-2-METHYLBUT-2-ENOATE'>OTK</scene>, <scene name='pdbligand=PTY:PHOSPHATIDYLETHANOLAMINE'>PTY</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2by4\|2by4]], [[2c8k\|2c8k]], [[3nal\|3nal]], [[3nan\|3nan]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nam OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nam RCSB], [http://www.ebi.ac.uk/pdbsum/3nam PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nam_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Thapsigargin (Tg), a specific inhibitor of sarco/endoplasmic Ca(2+)-ATPases (SERCA), binds with high affinity to the E2 conformation of these ATPases. SERCA inhibition leads to elevated calcium levels in the cytoplasm, which in turn induces apoptosis. We present x-ray crystallographic and intrinsic fluorescence data to show how Tg and chemical analogs of the compound with modified or removed side chains bind to isolated SERCA 1a membranes. This occurs by uptake via the membrane lipid followed by insertion into a resident intramembranous binding site with few adaptative changes. Our binding data indicate that a balanced hydrophobicity and accurate positioning of the side chains, provided by the central guaianolide ring structure, defines a pharmacophore of Tg that governs both high affinity and access to the protein-binding site. Tg analogs substituted with long linkers at O-8 extend from the binding site between transmembrane segments to the putative N-terminal Ca(2+) entry pathway. The long chain analogs provide a rational basis for the localization of the linker, the presence of which is necessary for enabling prostate-specific antigen to cleave peptide-conjugated prodrugs targeting SERCA of cancer cells (Denmeade, S. R., Jakobsen, C. M., Janssen, S., Khan, S. R., Garrett, E. S., Lilja, H., Christensen, S. B., and Isaacs, J. T. (2003) J. Natl. Cancer Inst. 95, 990-1000). Our study demonstrates the usefulness of a simple in vitro system to test and direct development toward the formulation of new Tg derivatives with improved properties for SERCA targeting. Finally, we propose that the Tg binding pocket may be a regulatory site that, for example, is sensitive to cholesterol.

-	~~{{STRUCTURE_3nam\| PDB=3nam \| SCENE= }}~~	+	Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs.,Winther AM, Liu H, Sonntag Y, Olesen C, le Maire M, Soehoel H, Olsen CE, Christensen SB, Nissen P, Moller JV J Biol Chem. 2010 Sep 10;285(37):28883-92. Epub 2010 Jun 15. PMID:20551329<ref>PMID:20551329</ref>

-	~~===SR Ca(2+)-ATPase in~~ the ~~HnE2 state complexed with the Thapsigargin derivative dOTg===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20551329}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nam]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].~~	+

	==See Also==		==See Also==
	*[[ATPase\|ATPase]]		*[[ATPase\|ATPase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020551329<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Calcium-transporting ATPase]]		[[Category: Calcium-transporting ATPase]]
	[[Category: Oryctolagus cuniculus]]		[[Category: Oryctolagus cuniculus]]
-	[[Category: Moller, J V.]]	+	[[Category: Moller, J V]]
-	[[Category: Nissen, P.]]	+	[[Category: Nissen, P]]
-	[[Category: Olesen, C.]]	+	[[Category: Olesen, C]]
-	[[Category: Sonntag, Y.]]	+	[[Category: Sonntag, Y]]
-	[[Category: Winther, A M.L.]]	+	[[Category: Winther, A M.L]]
	[[Category: Ca2+-atpase]]		[[Category: Ca2+-atpase]]
	[[Category: Calcium transport]]		[[Category: Calcium transport]]

OCA at 20:23, 20 October 2012

OCA — Sat, 20 Oct 2012 20:23:44 GMT

←Older revision		Revision as of 20:23, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3nam]] is a 1 chain structure ~~of [[ATPase]]~~ with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].	+	[[3nam]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].

	==See Also==		==See Also==

OCA: Protected "3nam" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 10:20:40 GMT

Protected "3nam" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:20, 27 July 2012

OCA at 10:20, 27 July 2012

OCA — Fri, 27 Jul 2012 10:20:39 GMT

←Older revision		Revision as of 10:20, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:3nam.png\|left\|200px]]		[[Image:3nam.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nam", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nam\| PDB=3nam \| SCENE= }}		{{STRUCTURE_3nam\| PDB=3nam \| SCENE= }}

	===SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg===		===SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20551329}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20551329 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20551329}}		{{ABSTRACT_PUBMED_20551329}}

	==About this Structure==		==About this Structure==
-	~~3NAM~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].	+	[[3nam]] is a 1 chain structure of [[ATPase]] with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].
		+
		+	==See Also==
		+	*[[ATPase\|ATPase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20551329~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020551329</ref><references group="xtra"/>
	[[Category: Calcium-transporting ATPase]]		[[Category: Calcium-transporting ATPase]]
	[[Category: Oryctolagus cuniculus]]		[[Category: Oryctolagus cuniculus]]
Line 43:		Line 34:
	[[Category: Transmembrane]]		[[Category: Transmembrane]]
	[[Category: Transport]]		[[Category: Transport]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:22:14 2010''

OCA at 11:13, 22 September 2010

OCA — Wed, 22 Sep 2010 11:13:16 GMT

←Older revision		Revision as of 11:13, 22 September 2010
Line 1:		Line 1:
	{{Seed}}		{{Seed}}
-	[[Image:3nam.~~jpg~~\|left\|200px]]	+	[[Image:3nam.png\|left\|200px]]

	<!--		<!--
Line 44:		Line 44:
	[[Category: Transport]]		[[Category: Transport]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 30 13~~:51:24 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:22:14 2010''

OCA at 09:45, 30 June 2010

OCA — Wed, 30 Jun 2010 09:45:49 GMT

←Older revision		Revision as of 09:45, 30 June 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nam.jpg\|left\|200px]]

-	The ~~entry 3nam~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nam", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nam\| PDB=3nam \| SCENE= }}

-	~~Authors: Winther, A.M.L., Sonntag, Y., Olesen, C., Moller, J.V., Nissen, P.~~	+	===SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg===

-	Description: SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun ~~16 08~~:29:40 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20551329}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20551329 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20551329}}
		+
		+	==About this Structure==
		+	3NAM is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAM OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20551329</ref><references group="xtra"/>
		+	[[Category: Calcium-transporting ATPase]]
		+	[[Category: Oryctolagus cuniculus]]
		+	[[Category: Moller, J V.]]
		+	[[Category: Nissen, P.]]
		+	[[Category: Olesen, C.]]
		+	[[Category: Sonntag, Y.]]
		+	[[Category: Winther, A M.L.]]
		+	[[Category: Ca2+-atpase]]
		+	[[Category: Calcium transport]]
		+	[[Category: Endoplasmic reticulum]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ion transport]]
		+	[[Category: P-type atpase]]
		+	[[Category: Prostate cancer]]
		+	[[Category: Sarcoplasmic reticulum]]
		+	[[Category: Serca]]
		+	[[Category: Thapsigargin]]
		+	[[Category: Transmembrane]]
		+	[[Category: Transport]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:51:24 2010''