3nau - Revision history

OCA at 16:45, 1 November 2023

OCA — Wed, 01 Nov 2023 16:45:27 GMT

←Older revision		Revision as of 16:45, 1 November 2023
Line 1:		Line 1:

	==Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)==		==Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)==
-	<StructureSection load='3nau' size='340' side='right' caption='[[3nau]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='3nau' size='340' side='right'caption='[[3nau]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nau]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NAU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nau]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NAU FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3nar\|3nar]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~"><~~b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">zhx2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [https://pdbe.org/3nau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [https://www.ebi.ac.uk/pdbsum/3nau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nau ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [~~http~~://pdbe.org/3nau PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nau PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nau ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>	+	[https://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Bird, L E~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~OPPF, Oxford Protein Production Facility~~]]	+	[[Category: Bird LE]]
-	[[Category: Owens~~, R J~~]]	+	[[Category: Owens RJ]]
-	[[Category: Ren, J]]	+	[[Category: Ren J]]
-	[[Category: Stammers~~, D K]]~~	+	[[Category: Stammers DK]]
-	~~[[Category: Corepressor]]~~	+
-	~~[[Category: Domain swapping]]~~	+
-	~~[[Category: Homeodomain]]~~	+
-	~~[[Category: Oppf]]~~	+
-	~~[[Category: Oxford protein production facility]]~~	+
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Zhx2~~]]	+

OCA at 12:59, 16 January 2019

OCA — Wed, 16 Jan 2019 12:59:59 GMT

←Older revision		Revision as of 12:59, 16 January 2019
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nau_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nau_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 11:00, 4 August 2016

OCA — Thu, 04 Aug 2016 11:00:32 GMT

←Older revision		Revision as of 11:00, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)==		==Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)==
	<StructureSection load='3nau' size='340' side='right' caption='[[3nau]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='3nau' size='340' side='right' caption='[[3nau]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAU FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nar\|3nar]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nar\|3nar]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">zhx2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">zhx2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [http://www.ebi.ac.uk/pdbsum/3nau PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [http://pdbe.org/3nau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [http://www.ebi.ac.uk/pdbsum/3nau PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nau ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nau ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nau" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Bird, L E]]		[[Category: Bird, L E]]
	[[Category: OPPF, Oxford Protein Production Facility]]		[[Category: OPPF, Oxford Protein Production Facility]]

OCA at 08:37, 25 December 2014

OCA — Thu, 25 Dec 2014 08:37:31 GMT

←Older revision		Revision as of 08:37, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [http://www.ebi.ac.uk/pdbsum/3nau PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [http://www.ebi.ac.uk/pdbsum/3nau PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 17:25, 18 December 2014

OCA — Thu, 18 Dec 2014 17:25:19 GMT

←Older revision		Revision as of 17:25, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3nau\| PDB=3nau \| SCENE= }}~~	+	==Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)==
-	===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===	+	<StructureSection load='3nau' size='340' side='right' caption='[[3nau]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20509910}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NAU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nar\|3nar]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">zhx2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nau OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nau RCSB], [http://www.ebi.ac.uk/pdbsum/3nau PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/na/3nau_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BACKGROUND: Zhx1 to 3 (zinc-fingers and homeoboxes) form a set of paralogous genes encoding multi-domain proteins. ZHX proteins consist of two zinc fingers followed by five homeodomains. ZHXs have biological roles in cell cycle control by acting as co-repressors of the transcriptional regulator Nuclear Factor Y. As part of a structural genomics project we have expressed single and multi-domain fragments of the different human ZHX genes for use in structure determination. RESULTS: A total of 30 single and multiple domain ZHX1-3 constructs selected from bioinformatics protocols were screened for soluble expression in E. coli using high throughput methodologies. Two homeodomains were crystallized leading to structures for ZHX1 HD4 and ZHX2 HD2. ZHX1 HD4, although closest matched to homeodomains from 'homez' and 'engrailed', showed structural differences, notably an additional C-terminal helix (helix V) which wrapped over helix I thereby making extensive contacts. Although ZHX2 HD2-3 was successfully expressed and purified, proteolysis occurred during crystallization yielding crystals of just HD2. The structure of ZHX2 HD2 showed an unusual open conformation with helix I undergoing 'domain-swapping' to form a homodimer. CONCLUSIONS: Although multiple-domain constructs of ZHX1 selected by bioinformatics studies could be expressed solubly, only single homeodomains yielded crystals. The crystal structure of ZHX1 HD4 showed additional hydrophobic interactions relative to many known homeodomains via extensive contacts formed by the novel C-terminal helix V with, in particular, helix I. Additionally, the replacement of some charged covariant residues (which are commonly observed to form salt bridges in non-homeotherms such as the Drosophila 'engrailed' homeodomain), by apolar residues further increases hydrophobic contacts within ZHX1 HD4, and potentially stability, relative to engrailed homeodomain. ZHX1 HD4 helix V points away from the normally observed DNA major groove binding site on homeodomains and thus would not obstruct the putative binding of nucleic acid. In contrast, for ZHX2 HD2 the observed altered conformation involving rearrangement of helix I, relative to the canonical homeodomain fold, disrupts the normal DNA binding site, although protein-protein binding is possible as observed in homodimer formation.

-	~~==Function==~~	+	Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains.,Bird LE, Ren J, Nettleship JE, Folkers GE, Owens RJ, Stammers DK BMC Struct Biol. 2010 May 28;10:13. PMID:20509910<ref>PMID:20509910</ref>
-	~~[[http://www~~.~~uniprot~~.~~org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA~~.<ref>PMID:~~12741956~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3nau]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:020509910</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Bird, L E.]]	+	[[Category: Bird, L E]]
-	[[Category: OPPF, Oxford Protein Production Facility.]]	+	[[Category: OPPF, Oxford Protein Production Facility]]
-	[[Category: Owens, R J.]]	+	[[Category: Owens, R J]]
-	[[Category: Ren, J.]]	+	[[Category: Ren, J]]
-	[[Category: Stammers, D K.]]	+	[[Category: Stammers, D K]]
	[[Category: Corepressor]]		[[Category: Corepressor]]
	[[Category: Domain swapping]]		[[Category: Domain swapping]]

OCA: Protected "3nau" [edit=sysop:move=sysop]

OCA — Wed, 17 Apr 2013 20:50:15 GMT

Protected "3nau" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:50, 17 April 2013

OCA at 20:50, 17 April 2013

OCA — Wed, 17 Apr 2013 20:50:10 GMT

←Older revision		Revision as of 20:50, 17 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3nau.jpg\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nau", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nau\| PDB=3nau \| SCENE= }}		{{STRUCTURE_3nau\| PDB=3nau \| SCENE= }}
-
	===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===		===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===
		+	{{ABSTRACT_PUBMED_20509910}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20509910}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov), where 20509910 is~~ the ~~PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_20509910}}~~	+

	==About this Structure==		==About this Structure==
-	~~3NAU~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].	+	[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20509910~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020509910</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Bird, L E.]]		[[Category: Bird, L E.]]
Line 38:		Line 25:
	[[Category: Transcription]]		[[Category: Transcription]]
	[[Category: Zhx2]]		[[Category: Zhx2]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 7 08:43:15 2010''

OCA at 04:37, 7 July 2010

OCA — Wed, 07 Jul 2010 04:37:24 GMT

←Older revision		Revision as of 04:37, 7 July 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nau.jpg\|left\|200px]]

-	The ~~entry 3nau~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nau", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nau\| PDB=3nau \| SCENE= }}

-	~~Authors: Ren~~, ~~J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF~~)	+	===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===

-	Description: Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Thu Jun 10 10~~:59:22 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20509910}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20509910 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20509910}}
		+
		+	==About this Structure==
		+	3NAU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20509910</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Bird, L E.]]
		+	[[Category: OPPF, Oxford Protein Production Facility.]]
		+	[[Category: Owens, R J.]]
		+	[[Category: Ren, J.]]
		+	[[Category: Stammers, D K.]]
		+	[[Category: Corepressor]]
		+	[[Category: Domain swapping]]
		+	[[Category: Homeodomain]]
		+	[[Category: Oppf]]
		+	[[Category: Oxford protein production facility]]
		+	[[Category: Structural genomic]]
		+	[[Category: Transcription]]
		+	[[Category: Zhx2]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 7 08:43:15 2010''

OCA: New page: '''Unreleased structure''' The entry 3nau is ON HOLD Authors: Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF) Description: Crystal structure...

OCA — Thu, 10 Jun 2010 06:54:35 GMT

New page: '''Unreleased structure''' The entry 3nau is ON HOLD Authors: Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF) Description: Crystal structure...

New page

'''Unreleased structure'''

The entry 3nau is ON HOLD

Authors: Ren, J., Bird, L.E., Owens, R.J., Stammers, D.K., Oxford Protein Production Facility (OPPF)

Description: Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 10 10:59:22 2010''