3nmp - Revision history

OCA at 09:17, 6 September 2023

OCA — Wed, 06 Sep 2023 09:17:39 GMT

←Older revision		Revision as of 09:17, 6 September 2023
Line 1:		Line 1:

	==Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin==		==Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin==
-	<StructureSection load='3nmp' size='340' side='right' caption='[[3nmp]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3nmp' size='340' side='right'caption='[[3nmp]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nmp]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NMP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nmp]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NMP FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN~~-2~~-YLMETHYL)NAPHTHALENE-~~1~~-SULFONAMIDE'>PYV</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[3mnh\|3mnh]], [[3nmn\|3nmn]], [[3nmt\|3nmt]], [[3nmv\|3nmv]], [[3kaz\|3kaz]], [[3kb0\|3kb0]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN-2-YLMETHYL)NAPHTHALENE-1-SULFONAMIDE'>PYV</scene></td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~"><~~b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">PYL2, RCAR14, At2g26040, T19L18.15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [https://pdbe.org/3nmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [https://www.ebi.ac.uk/pdbsum/3nmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nmp ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [~~http~~://pdbe.org/3nmp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nmp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nmp ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>	+	[https://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/3nmp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/3nmp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 32:		Line 31:

	==See Also==		==See Also==
-	*[[~~PYR/PYL/RCAR family of ABA receptors~~\|~~PYR/PYL/RCAR family of ABA receptors~~]]	+	*[[Abscisic acid receptor 3D structures\|Abscisic acid receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
-	[[Category: Kovach, A]]	+	[[Category: Large Structures]]
-	[[Category: Li, J]]	+	[[Category: Kovach A]]
-	[[Category: Melcher, K]]	+	[[Category: Li J]]
-	[[Category: Ng, L M]]	+	[[Category: Melcher K]]
-	[[Category: Soon, F F]]	+	[[Category: Ng L-M]]
-	[[Category: Suino-Powell~~, K M~~]]	+	[[Category: Soon F-F]]
-	[[Category: Xu~~, H E~~]]	+	[[Category: Suino-Powell KM]]
-	[[Category: Xu, Y]]	+	[[Category: Xu HE]]
-	[[Category: Yong, E L]]	+	[[Category: Xu Y]]
-	[[Category: Zhou~~, X E]]~~	+	[[Category: Yong E-L]]
-	~~[[Category: Helix-grip fold]]~~	+	[[Category: Zhou XE]]
-	~~[[Category: Hormone binding protein]]~~	+
-	~~[[Category: Plant hormone receptor]]~~	+
-	~~[[Category: Pyl2]]~~	+
-	~~[[Category: Pyrabactin~~]]	+

OCA at 08:48, 5 August 2016

OCA — Fri, 05 Aug 2016 08:48:51 GMT

←Older revision		Revision as of 08:48, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin==		==Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin==
	<StructureSection load='3nmp' size='340' side='right' caption='[[3nmp]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3nmp' size='340' side='right' caption='[[3nmp]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nmp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NMP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nmp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NMP FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN-2-YLMETHYL)NAPHTHALENE-1-SULFONAMIDE'>PYV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN-2-YLMETHYL)NAPHTHALENE-1-SULFONAMIDE'>PYV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mnh\|3mnh]], [[3nmn\|3nmn]], [[3nmt\|3nmt]], [[3nmv\|3nmv]], [[3kaz\|3kaz]], [[3kb0\|3kb0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mnh\|3mnh]], [[3nmn\|3nmn]], [[3nmt\|3nmt]], [[3nmv\|3nmv]], [[3kaz\|3kaz]], [[3kb0\|3kb0]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYL2, RCAR14, At2g26040, T19L18.15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ~~Arabidopsis thaliana~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYL2, RCAR14, At2g26040, T19L18.15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [http://www.ebi.ac.uk/pdbsum/3nmp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [http://pdbe.org/3nmp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [http://www.ebi.ac.uk/pdbsum/3nmp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nmp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nmp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nmp" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 35:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Kovach, A]]		[[Category: Kovach, A]]
	[[Category: Li, J]]		[[Category: Li, J]]

OCA at 00:54, 25 December 2014

OCA — Thu, 25 Dec 2014 00:54:47 GMT

←Older revision		Revision as of 00:54, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [http://www.ebi.ac.uk/pdbsum/3nmp PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [http://www.ebi.ac.uk/pdbsum/3nmp PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:10, 19 December 2014

OCA — Fri, 19 Dec 2014 07:10:15 GMT

←Older revision		Revision as of 07:10, 19 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3nmp\| PDB=3nmp \| SCENE= }}~~	+	==Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin==
-	===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===	+	<StructureSection load='3nmp' size='340' side='right' caption='[[3nmp]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~{{ABSTRACT_PUBMED_20729862}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nmp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NMP FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN-2-YLMETHYL)NAPHTHALENE-1-SULFONAMIDE'>PYV</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3mnh\|3mnh]], [[3nmn\|3nmn]], [[3nmt\|3nmt]], [[3nmv\|3nmv]], [[3kaz\|3kaz]], [[3kb0\|3kb0]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PYL2, RCAR14, At2g26040, T19L18.15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nmp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nmp RCSB], [http://www.ebi.ac.uk/pdbsum/3nmp PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nm/3nmp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The phytohormone abscisic acid (ABA) functions through a family of fourteen PYR/PYL receptors, which were identified by resistance to pyrabactin, a synthetic inhibitor of seed germination. ABA activates these receptors to inhibit type 2C protein phosphatases, such as ABI1, yet it remains unclear whether these receptors can be antagonized. Here we demonstrate that pyrabactin is an agonist of PYR1 and PYL1 but is unexpectedly an antagonist of PYL2. Crystal structures of the PYL2-pyrabactin and PYL1-pyrabactin-ABI1 complexes reveal the mechanism responsible for receptor-selective activation and inhibition, which enables us to design mutations that convert PYL1 to a pyrabactin-inhibited receptor and PYL2 to a pyrabactin-activated receptor and to identify new pyrabactin-based ABA receptor agonists. Together, our results establish a new concept of ABA receptor antagonism, illustrate its underlying mechanisms and provide a rational framework for discovering novel ABA receptor ligands.

-	~~==Function==~~	+	Identification and mechanism of ABA receptor antagonism.,Melcher K, Xu Y, Ng LM, Zhou XE, Soon FF, Chinnusamy V, Suino-Powell KM, Kovach A, Tham FS, Cutler SR, Li J, Yong EL, Zhu JK, Xu HE Nat Struct Mol Biol. 2010 Sep;17(9):1102-8. Epub 2010 Aug 22. PMID:20729862<ref>PMID:20729862</ref>
-	~~[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (~~ABA~~) required for ABA-mediated responses such as stomatal closure and germination inhibition~~. ~~Inhibits the activity of group~~-A ~~protein phosphatases type 2C~~ (~~PP2Cs~~) ~~when activated by ABA~~.~~<ref>~~PMID:~~19898420</ref>~~ <ref>PMID:~~19893533~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3nmp]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].~~	+	</div>

-	==~~Reference~~==	+	==See Also==
-	~~<ref group~~=~~"xtra">PMID:020729862</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	*[[PYR/PYL/RCAR family of ABA receptors\|PYR/PYL/RCAR family of ABA receptors]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
-	[[Category: Kovach, A.]]	+	[[Category: Kovach, A]]
-	[[Category: Li, J.]]	+	[[Category: Li, J]]
-	[[Category: Melcher, K.]]	+	[[Category: Melcher, K]]
-	[[Category: Ng, L M.]]	+	[[Category: Ng, L M]]
-	[[Category: Soon, F F.]]	+	[[Category: Soon, F F]]
-	[[Category: Suino-Powell, K M.]]	+	[[Category: Suino-Powell, K M]]
-	[[Category: Xu, H E.]]	+	[[Category: Xu, H E]]
-	[[Category: Xu, Y.]]	+	[[Category: Xu, Y]]
-	[[Category: Yong, E L.]]	+	[[Category: Yong, E L]]
-	[[Category: Zhou, X E.]]	+	[[Category: Zhou, X E]]
	[[Category: Helix-grip fold]]		[[Category: Helix-grip fold]]
	[[Category: Hormone binding protein]]		[[Category: Hormone binding protein]]

OCA: Protected "3nmp" [edit=sysop:move=sysop]

OCA — Wed, 24 Apr 2013 11:51:46 GMT

Protected "3nmp" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:51, 24 April 2013

OCA at 11:51, 24 April 2013

OCA — Wed, 24 Apr 2013 11:51:44 GMT

←Older revision		Revision as of 11:51, 24 April 2013
Line 1:		Line 1:
-	{{Seed}}
-	[[Image:3nmp.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nmp", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nmp\| PDB=3nmp \| SCENE= }}		{{STRUCTURE_3nmp\| PDB=3nmp \| SCENE= }}
-
	===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===		===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===
		+	{{ABSTRACT_PUBMED_20729862}}

-		+	==Function==
-	~~<!--~~	+	[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_20729862}}, adds the Publication Abstract to the page~~	+
-	~~(as it appears on PubMed at~~ http://www.~~pubmed~~.~~gov~~)~~, where 20729862 is the PubMed ID number~~.	+
-	-->	+
-	~~{{ABSTRACT_PUBMED_20729862}}~~	+

	==About this Structure==		==About this Structure==
-	~~3NMP~~ is a 3 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].	+	[[3nmp]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20729862~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020729862</ref><references group="xtra"/><references/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Kovach, A.]]		[[Category: Kovach, A.]]
Line 40:		Line 27:
	[[Category: Pyl2]]		[[Category: Pyl2]]
	[[Category: Pyrabactin]]		[[Category: Pyrabactin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:21:56 2010''

OCA at 07:13, 15 September 2010

OCA — Wed, 15 Sep 2010 07:13:14 GMT

←Older revision		Revision as of 07:13, 15 September 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3nmp.~~jpg~~\|left\|200px]]	+	[[Image:3nmp.png\|left\|200px]]

	<!--		<!--
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	===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===		===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20729862}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20729862 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20729862}}

	==About this Structure==		==About this Structure==
	3NMP is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].		3NMP is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20729862</ref><references group="xtra"/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Kovach, A.]]		[[Category: Kovach, A.]]
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	[[Category: Pyrabactin]]		[[Category: Pyrabactin]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 25 09~~:00:24 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:21:56 2010''

OCA at 04:52, 25 August 2010

OCA — Wed, 25 Aug 2010 04:52:33 GMT

←Older revision		Revision as of 04:52, 25 August 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nmp.jpg\|left\|200px]]

-	The ~~entry 3nmp~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nmp", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nmp\| PDB=3nmp \| SCENE= }}

-	~~Authors: Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.~~	+	===Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin===

-	Description: Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug ~~18 11~~:22:38 2010''	+	==About this Structure==
		+	3NMP is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NMP OCA].
		+	[[Category: Arabidopsis thaliana]]
		+	[[Category: Kovach, A.]]
		+	[[Category: Li, J.]]
		+	[[Category: Melcher, K.]]
		+	[[Category: Ng, L M.]]
		+	[[Category: Soon, F F.]]
		+	[[Category: Suino-Powell, K M.]]
		+	[[Category: Xu, H E.]]
		+	[[Category: Xu, Y.]]
		+	[[Category: Yong, E L.]]
		+	[[Category: Zhou, X E.]]
		+	[[Category: Helix-grip fold]]
		+	[[Category: Hormone binding protein]]
		+	[[Category: Plant hormone receptor]]
		+	[[Category: Pyl2]]
		+	[[Category: Pyrabactin]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 09:00:24 2010''

OCA at 07:15, 18 August 2010

OCA — Wed, 18 Aug 2010 07:15:05 GMT

←Older revision		Revision as of 07:15, 18 August 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3nmp is ON HOLD	+	The entry 3nmp is ON HOLD until Paper Publication

	Authors: Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.		Authors: Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.
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	Description: Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin		Description: Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 21 10~~:04:51 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 18 11:22:38 2010''

OCA at 05:58, 21 July 2010

OCA — Wed, 21 Jul 2010 05:58:26 GMT

←Older revision		Revision as of 05:58, 21 July 2010
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	The entry 3nmp is ON HOLD		The entry 3nmp is ON HOLD

-	Authors: X. ~~Edward Zhou~~ , ~~Karsten~~ Melcher , ~~Ley-Moy~~ Ng , ~~Fen~~-~~Fen~~ Soon , ~~Yong~~ Xu , ~~Kelly M~~. Suino-Powell , ~~Amanda~~ Kovach , ~~Jun~~ Li , ~~Eu-Leong~~ Yong , H. ~~Eric~~ Xu	+	Authors: Zhou, X.E., Melcher, K., Ng, L.-M., Soon, F.-F., Xu, Y., Suino-Powell, K.M., Kovach, A., Li, J., Yong, E.-L., Xu, H.E.

	Description: Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin		Description: Crystal structure of the abscisic receptor PYL2 mutant A93F in complex with pyrabactin

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jun 30 13~~:37:17 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 10:04:51 2010''