3nqj - Revision history

OCA at 09:19, 6 September 2023

OCA — Wed, 06 Sep 2023 09:19:35 GMT

←Older revision		Revision as of 09:19, 6 September 2023
Line 1:		Line 1:

	==Crystal structure of (CENP-A/H4)2 heterotetramer==		==Crystal structure of (CENP-A/H4)2 heterotetramer==
-	<StructureSection load='3nqj' size='340' side='right' caption='[[3nqj]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3nqj' size='340' side='right'caption='[[3nqj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nqj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3NQJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nqj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NQJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[3nqu\|3nqu~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [https://pdbe.org/3nqj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [https://www.ebi.ac.uk/pdbsum/3nqj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nqj ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [~~http~~://pdbe.org/3nqj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3nqj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3nqj ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>	+	[https://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 31:

	==See Also==		==See Also==
-	*[[Centromere protein\|Centromere protein]]	+	*[[Centromere protein 3D structure\|Centromere protein 3D structure]]
-	*[[Histone\|Histone]]	+	*[[Histone 3D structures\|Histone 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
-	[[Category: ~~Black, B E~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Sekulic, N~~]]	+	[[Category: Black BE]]
-	[[Category: ~~Alpha helix]]~~	+	[[Category: Sekulic N]]
-	~~[[Category: Centromere]]~~	+
-	~~[[Category: Dna binding protein]]~~	+
-	~~[[Category: Histone fold~~]]	+

OCA at 10:17, 30 January 2019

OCA — Wed, 30 Jan 2019 10:17:50 GMT

←Older revision		Revision as of 10:17, 30 January 2019
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/3nqj_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/3nqj_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 23:12, 5 August 2016

OCA — Fri, 05 Aug 2016 23:12:14 GMT

←Older revision		Revision as of 23:12, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of (CENP-A/H4)2 heterotetramer==		==Crystal structure of (CENP-A/H4)2 heterotetramer==
	<StructureSection load='3nqj' size='340' side='right' caption='[[3nqj]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3nqj' size='340' side='right' caption='[[3nqj]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3nqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NQJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3nqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NQJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nqu\|3nqu]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nqu\|3nqu]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~]), HIST1H4A, H4/A, H4FA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN]), HIST1H4A, H4/A, H4FA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [http://www.ebi.ac.uk/pdbsum/3nqj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [http://pdbe.org/3nqj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [http://www.ebi.ac.uk/pdbsum/3nqj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3nqj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nqj ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3nqj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 38:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Black, B E]]		[[Category: Black, B E]]
	[[Category: Sekulic, N]]		[[Category: Sekulic, N]]

OCA at 22:45, 25 December 2014

OCA — Thu, 25 Dec 2014 22:45:46 GMT

←Older revision		Revision as of 22:45, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [http://www.ebi.ac.uk/pdbsum/3nqj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [http://www.ebi.ac.uk/pdbsum/3nqj PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CENPA_HUMAN CENPA_HUMAN]] Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division. The CENPA-H4 heterotetramer can bind DNA by itself (in vitro).<ref>PMID:20739937</ref> <ref>PMID:21478274</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:31, 9 December 2014

OCA — Tue, 09 Dec 2014 13:31:01 GMT

←Older revision		Revision as of 13:31, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3nqj.~~png~~\|~~left~~\|200px]]	+	==Crystal structure of (CENP-A/H4)2 heterotetramer==
		+	<StructureSection load='3nqj' size='340' side='right' caption='[[3nqj]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3nqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3NQJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3nqu\|3nqu]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CENPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), HIST1H4A, H4/A, H4FA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3nqj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nqj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3nqj RCSB], [http://www.ebi.ac.uk/pdbsum/3nqj PDBsum]</span></td></tr>
		+	</table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nq/3nqj_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Centromeres are specified epigenetically, and the histone H3 variant CENP-A is assembled into the chromatin of all active centromeres. Divergence from H3 raises the possibility that CENP-A generates unique chromatin features to mark physically centromere location. Here we report the crystal structure of a subnucleosomal heterotetramer, human (CENP-A-H4)(2), that reveals three distinguishing properties encoded by the residues that comprise the CENP-A targeting domain (CATD; ref. 2): (1) a CENP-A-CENP-A interface that is substantially rotated relative to the H3-H3 interface; (2) a protruding loop L1 of the opposite charge as that on H3; and (3) strong hydrophobic contacts that rigidify the CENP-A-H4 interface. Residues involved in the CENP-A-CENP-A rotation are required for efficient incorporation into centromeric chromatin, indicating specificity for an unconventional nucleosome shape. DNA topological analysis indicates that CENP-A-containing nucleosomes are octameric with conventional left-handed DNA wrapping, in contrast to other recent proposals. Our results indicate that CENP-A marks centromere location by restructuring the nucleosome from within its folded histone core.

-	~~{{STRUCTURE_3nqj\| PDB=3nqj \| SCENE= }}~~	+	The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres.,Sekulic N, Bassett EA, Rogers DJ, Black BE Nature. 2010 Aug 25. PMID:20739937<ref>PMID:20739937</ref>

-	~~===Crystal structure of (CENP-A~~/~~H4)2 heterotetramer===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20739937}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3nqj]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].~~	+

	==See Also==		==See Also==
		+	*[[Centromere protein\|Centromere protein]]
	*[[Histone\|Histone]]		*[[Histone\|Histone]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020739937<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Black, B E.]]	+	[[Category: Black, B E]]
-	[[Category: Sekulic, N.]]	+	[[Category: Sekulic, N]]
	[[Category: Alpha helix]]		[[Category: Alpha helix]]
	[[Category: Centromere]]		[[Category: Centromere]]
	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]
	[[Category: Histone fold]]		[[Category: Histone fold]]

OCA at 22:32, 20 October 2012

OCA — Sat, 20 Oct 2012 22:32:57 GMT

←Older revision		Revision as of 22:32, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3nqj]] is a 2 chain structure ~~of [[Histone]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].	+	[[3nqj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].

	==See Also==		==See Also==

OCA: Protected "3nqj" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 16:40:58 GMT

Protected "3nqj" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:40, 27 July 2012

OCA at 16:40, 27 July 2012

OCA — Fri, 27 Jul 2012 16:40:57 GMT

←Older revision		Revision as of 16:40, 27 July 2012
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-	{{Seed}}
	[[Image:3nqj.png\|left\|200px]]		[[Image:3nqj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3nqj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3nqj\| PDB=3nqj \| SCENE= }}		{{STRUCTURE_3nqj\| PDB=3nqj \| SCENE= }}

	===Crystal structure of (CENP-A/H4)2 heterotetramer===		===Crystal structure of (CENP-A/H4)2 heterotetramer===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20739937}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_20739937}}		{{ABSTRACT_PUBMED_20739937}}

	==About this Structure==		==About this Structure==
-	~~3NQJ~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].	+	[[3nqj]] is a 2 chain structure of [[Histone]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].
		+
		+	==See Also==
		+	*[[Histone\|Histone]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20739937~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020739937</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Black, B E.]]		[[Category: Black, B E.]]
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	[[Category: Dna binding protein]]		[[Category: Dna binding protein]]
	[[Category: Histone fold]]		[[Category: Histone fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:29:21 2010''

OCA at 09:20, 10 September 2010

OCA — Fri, 10 Sep 2010 09:20:51 GMT

←Older revision		Revision as of 09:20, 10 September 2010
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	{{Seed}}		{{Seed}}
-	[[Image:3nqj.~~jpg~~\|left\|200px]]	+	[[Image:3nqj.png\|left\|200px]]

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	===Crystal structure of (CENP-A/H4)2 heterotetramer===		===Crystal structure of (CENP-A/H4)2 heterotetramer===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20739937}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20739937 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20739937}}

	==About this Structure==		==About this Structure==
	3NQJ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].		3NQJ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:20739937</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Black, B E.]]		[[Category: Black, B E.]]
Line 23:		Line 32:
	[[Category: Histone fold]]		[[Category: Histone fold]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Aug 25 09~~:01:02 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:29:21 2010''

OCA at 04:53, 25 August 2010

OCA — Wed, 25 Aug 2010 04:53:12 GMT

←Older revision		Revision as of 04:53, 25 August 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3nqj.jpg\|left\|200px]]

-	The ~~entry 3nqj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3nqj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3nqj\| PDB=3nqj \| SCENE= }}

-	~~Authors: Sekulic, N., Black, B.E.~~	+	===Crystal structure of (CENP-A/H4)2 heterotetramer===

-	Description: Crystal structure of (CENP-A/H4)2 heterotetramer

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Jul 28 12:~~25:42 2010''	+	==About this Structure==
		+	3NQJ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NQJ OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Black, B E.]]
		+	[[Category: Sekulic, N.]]
		+	[[Category: Alpha helix]]
		+	[[Category: Centromere]]
		+	[[Category: Dna binding protein]]
		+	[[Category: Histone fold]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 09:01:02 2010''