3o6w - Revision history

OCA at 09:29, 6 September 2023

OCA — Wed, 06 Sep 2023 09:29:52 GMT

←Older revision		Revision as of 09:29, 6 September 2023
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	<StructureSection load='3o6w' size='340' side='right'caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='3o6w' size='340' side='right'caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_56498 Atcc 56498~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O6W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O6W FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.48Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>KLLA0D11352g, RAG5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~28985 ATCC 56498])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [https://pdbe.org/3o6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [https://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [https://pdbe.org/3o6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [https://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HXK_KLULA HXK_KLULA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 56498]]~~	+	[[Category: Kluyveromyces lactis]]
-	~~[[Category: Hexokinase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Keim, A]]	+	[[Category: Keim A]]
-	[[Category: Kettner, K]]	+	[[Category: Kettner K]]
-	[[Category: Kriegel~~, T M~~]]	+	[[Category: Kriegel TM]]
-	[[Category: Kuettner~~, E B~~]]	+	[[Category: Kuettner EB]]
-	[[Category: Strater, N]]	+	[[Category: Strater N]]
-	~~[[Category: Atp binding]]~~	+
-	~~[[Category: Glucose repression]]~~	+
-	~~[[Category: Glycolysis]]~~	+
-	~~[[Category: Mig1 binding]]~~	+
-	~~[[Category: Rnaseh-like fold]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:17, 12 May 2022

OCA — Thu, 12 May 2022 07:17:17 GMT

←Older revision		Revision as of 07:17, 12 May 2022
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	==Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)==		==Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)==
-	<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>	+	<StructureSection load='3o6w' size='340' side='right'caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3O6W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O6W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [~~http~~://pdbe.org/3o6w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [https://pdbe.org/3o6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [https://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3o6w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3o6w" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Hexokinase 3D structures\|Hexokinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 28:
	[[Category: Atcc 56498]]		[[Category: Atcc 56498]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
		+	[[Category: Large Structures]]
	[[Category: Keim, A]]		[[Category: Keim, A]]
	[[Category: Kettner, K]]		[[Category: Kettner, K]]

OCA at 08:40, 8 November 2017

OCA — Wed, 08 Nov 2017 08:40:22 GMT

←Older revision		Revision as of 08:40, 8 November 2017
Line 3:		Line 3:
	<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Candida_sphaerica Candida sphaerica~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_56498 Atcc 56498]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6W FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ~~Candida sphaerica~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ATCC 56498])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [http://pdbe.org/3o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [http://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [http://pdbe.org/3o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [http://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3o6w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3o6w" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Hexokinase\|Hexokinase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Candida sphaerica~~]]	+	[[Category: Atcc 56498]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Keim, A]]		[[Category: Keim, A]]

OCA at 04:07, 10 December 2016

OCA — Sat, 10 Dec 2016 04:07:52 GMT

←Older revision		Revision as of 04:07, 10 December 2016
Line 1:		Line 1:
		+
	==Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)==		==Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)==
	<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>		<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Kluyveromyces_lactis Kluyveromyces lactis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_sphaerica Candida sphaerica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6W FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 ~~Kluyveromyces lactis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 Candida sphaerica])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [http://www.ebi.ac.uk/pdbsum/3o6w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [http://pdbe.org/3o6w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [http://www.ebi.ac.uk/pdbsum/3o6w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3o6w ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3o6w" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Candida sphaerica]]
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
-	[[Category: Kluyveromyces lactis]]
	[[Category: Keim, A]]		[[Category: Keim, A]]
	[[Category: Kettner, K]]		[[Category: Kettner, K]]

OCA at 11:26, 9 December 2014

OCA — Tue, 09 Dec 2014 11:26:53 GMT

←Older revision		Revision as of 11:26, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3o6w.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)==
		+	<StructureSection load='3o6w' size='340' side='right' caption='[[3o6w]], [[Resolution\|resolution]] 1.48Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3O6W FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3o08\|3o08]], [[3o1b\|3o1b]], [[3o1w\|3o1w]], [[3o4w\|3o4w]], [[3o5b\|3o5b]], [[3o80\|3o80]], [[3o8m\|3o8m]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">KLLA0D11352g, RAG5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=28985 Kluyveromyces lactis])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3o6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o6w OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3o6w RCSB], [http://www.ebi.ac.uk/pdbsum/3o6w PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of the unique hexokinase KlHxk1 of the yeast Kluyveromyces lactis were determined using eight independent crystal forms. In five crystal forms, a symmetrical ring-shaped homodimer was observed, corresponding to the physiological dimer existing in solution as shown by small-angle x-ray scattering. The dimer has a head-to-tail arrangement such that the small domain of one subunit interacts with the large domain of the other subunit. Dimer formation requires favorable interactions of the 15 N-terminal amino acids that are part of the large domain with amino acids of the small domain of the opposite subunit, respectively. The head-to-tail arrangement involving both domains of the two KlHxk1 subunits is appropriate to explain the reduced activity of the homodimer as compared with the monomeric enzyme and the influence of substrates and products on dimer formation and dissociation. In particular, the structure of the symmetrical KlHxk1 dimer serves to explain why phosphorylation of conserved residue Ser-15 may cause electrostatic repulsions with nearby negatively charged residues of the adjacent subunit, thereby inducing a dissociation of the homologous dimeric hexokinases KlHxk1 and ScHxk2. Two complex structures of KlHxk1 with bound glucose provide a molecular model of substrate binding to the open conformation and the subsequent classical domain closure motion of yeast hexokinases. The entirety of the novel data extends the current concept of glucose signaling in yeast and complements the induced-fit model by integrating the events of N-terminal phosphorylation and dissociation of homodimeric yeast hexokinases.

-	~~{{STRUCTURE_3o6w\| PDB=3o6w \| SCENE= }}~~	+	Crystal Structure of Hexokinase KlHxk1 of Kluyveromyces lactis: A MOLECULAR BASIS FOR UNDERSTANDING THE CONTROL OF YEAST HEXOKINASE FUNCTIONS VIA COVALENT MODIFICATION AND OLIGOMERIZATION.,Kuettner EB, Kettner K, Keim A, Svergun DI, Volke D, Singer D, Hoffmann R, Muller EC, Otto A, Kriegel TM, Strater N J Biol Chem. 2010 Dec 24;285(52):41019-33. Epub 2010 Oct 12. PMID:20943665<ref>PMID:20943665</ref>

-	~~===Crystal structure~~ of ~~monomeric KlHxk1 in crystal form VIII (open state)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_20943665}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3o6w]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].~~	+

	==See Also==		==See Also==
	*[[Hexokinase\|Hexokinase]]		*[[Hexokinase\|Hexokinase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:020943665<~~/~~ref~~><~~ref group="xtra">PMID:017565189</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]
-	[[Category: Keim, A.]]	+	[[Category: Keim, A]]
-	[[Category: Kettner, K.]]	+	[[Category: Kettner, K]]
-	[[Category: Kriegel, T M.]]	+	[[Category: Kriegel, T M]]
-	[[Category: Kuettner, E B.]]	+	[[Category: Kuettner, E B]]
-	[[Category: Strater, N.]]	+	[[Category: Strater, N]]
	[[Category: Atp binding]]		[[Category: Atp binding]]
	[[Category: Glucose repression]]		[[Category: Glucose repression]]
	[[Category: Glycolysis]]		[[Category: Glycolysis]]
-	[[Category: Hexokinase]]
	[[Category: Mig1 binding]]		[[Category: Mig1 binding]]
	[[Category: Rnaseh-like fold]]		[[Category: Rnaseh-like fold]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 10:14, 20 October 2012

OCA — Sat, 20 Oct 2012 10:14:57 GMT

←Older revision		Revision as of 10:14, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3o6w]] is a 2 chain structure ~~of [[Hexokinase]]~~ with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].	+	[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].

	==See Also==		==See Also==

OCA at 01:28, 26 July 2012

OCA — Thu, 26 Jul 2012 01:28:26 GMT

←Older revision		Revision as of 01:28, 26 July 2012
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	[[Image:3o6w.png\|left\|200px]]		[[Image:3o6w.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3o6w", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3o6w\| PDB=3o6w \| SCENE= }}		{{STRUCTURE_3o6w\| PDB=3o6w \| SCENE= }}

	===Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)===		===Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_20943665}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 20943665 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_20943665}}		{{ABSTRACT_PUBMED_20943665}}

	==About this Structure==		==About this Structure==
-	[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].	+	[[3o6w]] is a 2 chain structure of [[Hexokinase]] with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].
		+
		+	==See Also==
		+	*[[Hexokinase\|Hexokinase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~20943665~~</ref><ref group="xtra">PMID:~~17565189~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:020943665</ref><ref group="xtra">PMID:017565189</ref><references group="xtra"/>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]

OCA: Protected "3o6w" [edit=sysop:move=sysop]

OCA — Wed, 29 Dec 2010 17:56:21 GMT

Protected "3o6w" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:56, 29 December 2010

OCA at 17:56, 29 December 2010

OCA — Wed, 29 Dec 2010 17:56:19 GMT

←Older revision		Revision as of 17:56, 29 December 2010
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3o6w.png\|left\|200px]]
-	[[Image:3o6w.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	===Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)===		===Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_20943665}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 20943665 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_20943665}}

	==About this Structure==		==About this Structure==
-	~~3O6W~~ is a 2 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].	+	[[3o6w]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:17565189</ref><references group="xtra"/>	+	<ref group="xtra">PMID:20943665</ref><ref group="xtra">PMID:17565189</ref><references group="xtra"/>
	[[Category: Hexokinase]]		[[Category: Hexokinase]]
	[[Category: Kluyveromyces lactis]]		[[Category: Kluyveromyces lactis]]
Line 32:		Line 37:
	[[Category: Rnaseh-like fold]]		[[Category: Rnaseh-like fold]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:50:01 2010''

OCA at 07:40, 13 October 2010

OCA — Wed, 13 Oct 2010 07:40:13 GMT

←Older revision		Revision as of 07:40, 13 October 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3o6w.jpg\|left\|200px]]

-	The ~~entry 3o6w~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3o6w", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3o6w\| PDB=3o6w \| SCENE= }}

-	~~Authors: Kuettner, E.B., Kettner, K., Keim, A., Kriegel, T.M., Strater, N.~~	+	===Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)===

-	Description: Crystal structure of monomeric KlHxk1 in crystal form VIII (open state)

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Aug 18 11~~:25:05 2010''	+	==About this Structure==
		+	3O6W is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Kluyveromyces_lactis Kluyveromyces lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O6W OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:17565189</ref><references group="xtra"/>
		+	[[Category: Hexokinase]]
		+	[[Category: Kluyveromyces lactis]]
		+	[[Category: Keim, A.]]
		+	[[Category: Kettner, K.]]
		+	[[Category: Kriegel, T M.]]
		+	[[Category: Kuettner, E B.]]
		+	[[Category: Strater, N.]]
		+	[[Category: Atp binding]]
		+	[[Category: Glucose repression]]
		+	[[Category: Glycolysis]]
		+	[[Category: Hexokinase]]
		+	[[Category: Mig1 binding]]
		+	[[Category: Rnaseh-like fold]]
		+	[[Category: Transferase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:50:01 2010''