3p0l - Revision history

OCA at 09:47, 6 September 2023

OCA — Wed, 06 Sep 2023 09:47:12 GMT

←Older revision		Revision as of 09:47, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~STAR~~, ~~STARD1 (~~[~~https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=9606 HUMAN])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.	+	[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	+	[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H]]~~	+	[[Category: Arrowsmith CH]]
-	~~[[Category: Berg, S Van Den~~]]	+	[[Category: Berglund H]]
-	[[Category: Berglund, H]]	+	[[Category: Busam RD]]
-	[[Category: Busam~~, R D~~]]	+	[[Category: Collins R]]
-	[[Category: Collins, R]]	+	[[Category: Dahlgren LG]]
-	[[Category: Dahlgren~~, L G~~]]	+	[[Category: Edwards AM]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Flodin S]]
-	[[Category: Flodin, S]]	+	[[Category: Flores A]]
-	[[Category: Flores, A]]	+	[[Category: Graslund S]]
-	[[Category: Graslund, S]]	+	[[Category: Hallberg BM]]
-	[[Category: Hallberg~~, B M~~]]	+	[[Category: Hammarstrom M]]
-	[[Category: Hammarstrom, M]]	+	[[Category: Herman MD]]
-	[[Category: Herman~~, M D~~]]	+	[[Category: Johansson A]]
-	[[Category: Johansson, A]]	+	[[Category: Johansson I]]
-	[[Category: Johansson, I]]	+	[[Category: Kallas A]]
-	[[Category: Kallas, A]]	+	[[Category: Karlberg T]]
-	[[Category: Karlberg, T]]	+	[[Category: Kotenyova T]]
-	[[Category: Kotenyova, T]]	+	[[Category: Lehtio L]]
-	[[Category: Lehtio, L]]	+	[[Category: Moche M]]
-	[[Category: Moche, M]]	+	[[Category: Nilsson ME]]
-	[[Category: Nilsson~~, M E~~]]	+	[[Category: Nordlund P]]
-	[[Category: Nordlund, P]]	+	[[Category: Nyman T]]
-	[[Category: Nyman, T]]	+	[[Category: Persson C]]
-	[[Category: Persson, C]]	+	[[Category: Sagemark J]]
-	~~[[Category: Structural genomic~~]]	+	[[Category: Schuler H]]
-	[[Category: Sagemark, J]]	+	[[Category: Siponen M]]
-	[[Category: Schuler, H]]	+	[[Category: Sundstrom M]]
-	[[Category: Siponen, M]]	+	[[Category: Svensson L]]
-	[[Category: Sundstrom, M]]	+	[[Category: Thorsell AG]]
-	[[Category: Svensson, L]]	+	[[Category: Tresaugues L]]
-	[[Category: Thorsell~~, A G~~]]	+	[[Category: Van Den Berg S]]
-	[[Category: Tresaugues, L]]	+	[[Category: Weigelt J]]
-	[[Category: ~~Weigelt, J~~]]	+	[[Category: Welin M]]
-	[[Category: ~~Welin, M~~]]	+
-	[[Category: ~~Cholesterol]]~~	+
-	~~[[Category: Cholesterol transport]]~~	+
-	~~[[Category: Mitochondria]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Start domain]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 11:06, 18 May 2022

OCA — Wed, 18 May 2022 11:06:36 GMT

←Older revision		Revision as of 11:06, 18 May 2022
Line 1:		Line 1:

	==Human steroidogenic acute regulatory protein==		==Human steroidogenic acute regulatory protein==
-	<StructureSection load='3p0l' size='340' side='right' caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='3p0l' size='340' side='right'caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3P0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [~~http~~://pdbe.org/3p0l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [https://pdbe.org/3p0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [https://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[~~http~~://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.	+	[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.	+	[[https://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Berg, S Van Den]]		[[Category: Berg, S Van Den]]

OCA at 08:03, 4 August 2016

OCA — Thu, 04 Aug 2016 08:03:12 GMT

←Older revision		Revision as of 08:03, 4 August 2016
Line 1:		Line 1:
		+
	==Human steroidogenic acute regulatory protein==		==Human steroidogenic acute regulatory protein==
	<StructureSection load='3p0l' size='340' side='right' caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='3p0l' size='340' side='right' caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P0L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [http://www.ebi.ac.uk/pdbsum/3p0l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [http://pdbe.org/3p0l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [http://www.ebi.ac.uk/pdbsum/3p0l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p0l ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3p0l" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Berg, S Van Den]]		[[Category: Berg, S Van Den]]

OCA at 21:54, 3 January 2015

OCA — Sat, 03 Jan 2015 21:54:05 GMT

←Older revision		Revision as of 21:54, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P0L FirstGlance]. <br>		<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [http://www.ebi.ac.uk/pdbsum/3p0l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [http://www.ebi.ac.uk/pdbsum/3p0l PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Disease ==		== Disease ==
	[[http://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.		[[http://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
Line 16:		Line 16:
	Comparative structural analysis of lipid binding START domains.,Thorsell AG, Lee WH, Persson C, Siponen MI, Nilsson M, Busam RD, Kotenyova T, Schuler H, Lehtio L PLoS One. 2011;6(6):e19521. Epub 2011 Jun 30. PMID:21738568<ref>PMID:21738568</ref>		Comparative structural analysis of lipid binding START domains.,Thorsell AG, Lee WH, Persson C, Siponen MI, Nilsson M, Busam RD, Kotenyova T, Schuler H, Lehtio L PLoS One. 2011;6(6):e19521. Epub 2011 Jun 30. PMID:21738568<ref>PMID:21738568</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 23:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Arrowsmith, C H.]]	+	[[Category: Arrowsmith, C H]]
-	[[Category: Berg, S Van Den.]]	+	[[Category: Berg, S Van Den]]
-	[[Category: Berglund, H.]]	+	[[Category: Berglund, H]]
-	[[Category: Busam, R D.]]	+	[[Category: Busam, R D]]
-	[[Category: Collins, R.]]	+	[[Category: Collins, R]]
-	[[Category: Dahlgren, L G.]]	+	[[Category: Dahlgren, L G]]
-	[[Category: Edwards, A M.]]	+	[[Category: Edwards, A M]]
-	[[Category: Flodin, S.]]	+	[[Category: Flodin, S]]
-	[[Category: Flores, A.]]	+	[[Category: Flores, A]]
-	[[Category: Graslund, S.]]	+	[[Category: Graslund, S]]
-	[[Category: Hallberg, B M.]]	+	[[Category: Hallberg, B M]]
-	[[Category: Hammarstrom, M.]]	+	[[Category: Hammarstrom, M]]
-	[[Category: Herman, M D.]]	+	[[Category: Herman, M D]]
-	[[Category: Johansson, A.]]	+	[[Category: Johansson, A]]
-	[[Category: Johansson, I.]]	+	[[Category: Johansson, I]]
-	[[Category: Kallas, A.]]	+	[[Category: Kallas, A]]
-	[[Category: Karlberg, T.]]	+	[[Category: Karlberg, T]]
-	[[Category: Kotenyova, T.]]	+	[[Category: Kotenyova, T]]
-	[[Category: Lehtio, L.]]	+	[[Category: Lehtio, L]]
-	[[Category: Moche, M.]]	+	[[Category: Moche, M]]
-	[[Category: Nilsson, M E.]]	+	[[Category: Nilsson, M E]]
-	[[Category: Nordlund, P.]]	+	[[Category: Nordlund, P]]
-	[[Category: Nyman, T.]]	+	[[Category: Nyman, T]]
-	[[Category: Persson, C.]]	+	[[Category: Persson, C]]
-	[[Category: ~~SGC,~~ Structural ~~Genomics Consortium.~~]]	+	[[Category: Structural genomic]]
-	[[Category: Sagemark, J.]]	+	[[Category: Sagemark, J]]
-	[[Category: Schuler, H.]]	+	[[Category: Schuler, H]]
-	[[Category: Siponen, M.]]	+	[[Category: Siponen, M]]
-	[[Category: Sundstrom, M.]]	+	[[Category: Sundstrom, M]]
-	[[Category: Svensson, L.]]	+	[[Category: Svensson, L]]
-	[[Category: Thorsell, A G.]]	+	[[Category: Thorsell, A G]]
-	[[Category: Tresaugues, L.]]	+	[[Category: Tresaugues, L]]
-	[[Category: Weigelt, J.]]	+	[[Category: Weigelt, J]]
-	[[Category: Welin, M.]]	+	[[Category: Welin, M]]
	[[Category: Cholesterol]]		[[Category: Cholesterol]]
	[[Category: Cholesterol transport]]		[[Category: Cholesterol transport]]
Line 62:		Line 62:
	[[Category: Sgc]]		[[Category: Sgc]]
	[[Category: Start domain]]		[[Category: Start domain]]
-	[[Category: Structural genomics consortium]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 10:29, 28 May 2014

OCA — Wed, 28 May 2014 10:29:34 GMT

←Older revision		Revision as of 10:29, 28 May 2014
Line 1:		Line 1:
-	[[~~Image:~~3p0l.~~png~~\|~~left\|200px~~]]	+	==Human steroidogenic acute regulatory protein==
		+	<StructureSection load='3p0l' size='340' side='right' caption='[[3p0l]], [[Resolution\|resolution]] 3.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P0L FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">STAR, STARD1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p0l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p0l RCSB], [http://www.ebi.ac.uk/pdbsum/3p0l PDBsum]</span></td></tr>
		+	<table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Non-classic congenital lipoid adrenal hyperplasia due to STAR deficency;Classic congenital lipoid adrenal hyperplasia due to STAR deficency;Familial glucocorticoid deficiency. The disease is caused by mutations affecting the gene represented in this entry.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/STAR_HUMAN STAR_HUMAN]] Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BACKGROUND: Steroidogenic acute regulatory (StAR) protein related lipid transfer (START) domains are small globular modules that form a cavity where lipids and lipid hormones bind. These domains can transport ligands to facilitate lipid exchange between biological membranes, and they have been postulated to modulate the activity of other domains of the protein in response to ligand binding. More than a dozen human genes encode START domains, and several of them are implicated in a disease. PRINCIPAL FINDINGS: We report crystal structures of the human STARD1, STARD5, STARD13 and STARD14 lipid transfer domains. These represent four of the six functional classes of START domains. SIGNIFICANCE: Sequence alignments based on these and previously reported crystal structures define the structural determinants of human START domains, both those related to structural framework and those involved in ligand specificity. ENHANCED VERSION: This article can also be viewed as an enhanced version in which the text of the article is integrated with interactive 3D representations and animated transitions. Please note that a web plugin is required to access this enhanced functionality. Instructions for the installation and use of the web plugin are available in Text S1.

-	~~<!--~~	+	Comparative structural analysis of lipid binding START domains.,Thorsell AG, Lee WH, Persson C, Siponen MI, Nilsson M, Busam RD, Kotenyova T, Schuler H, Lehtio L PLoS One. 2011;6(6):e19521. Epub 2011 Jun 30. PMID:21738568<ref>PMID:21738568</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3p0l"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3p0l\| PDB=3p0l \| SCENE= }}~~	+

-	~~===Human steroidogenic acute regulatory protein===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_21738568}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21738568 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21738568}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3p0l]] is a 4 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021738568<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]

OCA: Protected "3p0l" [edit=sysop:move=sysop]

OCA — Wed, 21 Sep 2011 05:11:24 GMT

Protected "3p0l" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:11, 21 September 2011

OCA at 05:11, 21 September 2011

OCA — Wed, 21 Sep 2011 05:11:23 GMT

←Older revision		Revision as of 05:11, 21 September 2011
Line 1:		Line 1:
-	~~{{Seed}}~~	+	[[Image:3p0l.png\|left\|200px]]
-	[[Image:3p0l.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	===Human steroidogenic acute regulatory protein===		===Human steroidogenic acute regulatory protein===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21738568}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21738568 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21738568}}

	==About this Structure==		==About this Structure==
-	~~3P0L~~ is a 4 ~~chains~~ structure with ~~sequences~~ from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA].	+	[[3p0l]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021738568</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Arrowsmith, C H.]]		[[Category: Arrowsmith, C H.]]
Line 57:		Line 65:
	[[Category: Structural genomics consortium]]		[[Category: Structural genomics consortium]]
	[[Category: Transport protein]]		[[Category: Transport protein]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:19:24 2010''

OCA at 11:07, 24 November 2010

OCA — Wed, 24 Nov 2010 11:07:54 GMT

←Older revision		Revision as of 11:07, 24 November 2010
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3p0l.jpg\|left\|200px]]

-	The ~~entry 3p0l~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3p0l", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3p0l\| PDB=3p0l \| SCENE= }}

-	Authors: Lehtio, L., Siponen, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T.,	+	===Human steroidogenic acute regulatory protein===

-	Description: Human steroidogenic acute regulatory protein

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct 6 05~~:50:37 2010''	+	==About this Structure==
		+	3P0L is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P0L OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Arrowsmith, C H.]]
		+	[[Category: Berg, S Van Den.]]
		+	[[Category: Berglund, H.]]
		+	[[Category: Busam, R D.]]
		+	[[Category: Collins, R.]]
		+	[[Category: Dahlgren, L G.]]
		+	[[Category: Edwards, A M.]]
		+	[[Category: Flodin, S.]]
		+	[[Category: Flores, A.]]
		+	[[Category: Graslund, S.]]
		+	[[Category: Hallberg, B M.]]
		+	[[Category: Hammarstrom, M.]]
		+	[[Category: Herman, M D.]]
		+	[[Category: Johansson, A.]]
		+	[[Category: Johansson, I.]]
		+	[[Category: Kallas, A.]]
		+	[[Category: Karlberg, T.]]
		+	[[Category: Kotenyova, T.]]
		+	[[Category: Lehtio, L.]]
		+	[[Category: Moche, M.]]
		+	[[Category: Nilsson, M E.]]
		+	[[Category: Nordlund, P.]]
		+	[[Category: Nyman, T.]]
		+	[[Category: Persson, C.]]
		+	[[Category: SGC, Structural Genomics Consortium.]]
		+	[[Category: Sagemark, J.]]
		+	[[Category: Schuler, H.]]
		+	[[Category: Siponen, M.]]
		+	[[Category: Sundstrom, M.]]
		+	[[Category: Svensson, L.]]
		+	[[Category: Thorsell, A G.]]
		+	[[Category: Tresaugues, L.]]
		+	[[Category: Weigelt, J.]]
		+	[[Category: Welin, M.]]
		+	[[Category: Cholesterol]]
		+	[[Category: Cholesterol transport]]
		+	[[Category: Mitochondria]]
		+	[[Category: Sgc]]
		+	[[Category: Start domain]]
		+	[[Category: Structural genomics consortium]]
		+	[[Category: Transport protein]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 24 14:19:24 2010''

OCA: New page: '''Unreleased structure''' The entry 3p0l is ON HOLD Authors: Lehtio, L., Siponen, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S...

OCA — Wed, 06 Oct 2010 02:41:05 GMT

New page: '''Unreleased structure''' The entry 3p0l is ON HOLD Authors: Lehtio, L., Siponen, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S...

New page

'''Unreleased structure'''

The entry 3p0l is ON HOLD

Authors: Lehtio, L., Siponen, M., Arrowsmith, C.H., Berglund, H., Busam, R.D., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Hallberg, B.M., Herman, M.D., Johansson, A., Johansson, I., Kallas, A., Karlberg, T.,

Description: Human steroidogenic acute regulatory protein

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 05:50:37 2010''