3p1p - Revision history

OCA at 17:00, 1 November 2023

OCA — Wed, 01 Nov 2023 17:00:46 GMT

←Older revision		Revision as of 17:00, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3p1p' size='340' side='right'caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='3p1p' size='340' side='right'caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.95Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~SEP~~:~~PHOSPHOSERINE~~'>~~SEP~~</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td>~~<td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3iqu\|3iqu]]~~, ~~[[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]~~<~~/div></td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">SFN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [https://pdbe.org/3p1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [https://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [https://pdbe.org/3p1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [https://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] Intellectual deficit, Birk-Barel type. Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:[https://omim.org/entry/612292 612292]]: A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:18678320</ref>	+	[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN] Intellectual deficit, Birk-Barel type. Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:[https://omim.org/entry/612292 612292]: A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:18678320</ref>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>	+	[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Anders, C]]	+	[[Category: Anders C]]
-	[[Category: Higuchi, Y]]	+	[[Category: Higuchi Y]]
-	[[Category: Kato, N]]	+	[[Category: Kato N]]
-	[[Category: Ottmann, C]]	+	[[Category: Ottmann C]]
-	[[Category: Schumacher, B]]	+	[[Category: Schumacher B]]
-	[[Category: Thiel, P]]	+	[[Category: Thiel P]]
-	~~[[Category: Adapter protein]]~~	+
-	~~[[Category: Helical protein]]~~	+
-	~~[[Category: Nucleus]]~~	+
-	~~[[Category: Peptide binding protein]]~~	+
-	~~[[Category: Phosphoprotein~~]]	+

OCA at 11:10, 18 May 2022

OCA — Wed, 18 May 2022 11:10:50 GMT

←Older revision		Revision as of 11:10, 18 May 2022
Line 1:		Line 1:

	==Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide==		==Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide==
-	<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>	+	<StructureSection load='3p1p' size='340' side='right'caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3P1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [~~http~~://pdbe.org/3p1p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [https://pdbe.org/3p1p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [https://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[[~~http~~://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] Intellectual deficit, Birk-Barel type. Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:[~~http~~://omim.org/entry/612292 612292]]: A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:18678320</ref>	+	[[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] Intellectual deficit, Birk-Barel type. Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:[https://omim.org/entry/612292 612292]]: A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:18678320</ref>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[~~http~~://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>	+	[[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[https://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:

	==See Also==		==See Also==
-	*[[14-3-3 protein\|14-3-3 protein]]	+	*[[14-3-3 protein 3D structures\|14-3-3 protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Anders, C]]		[[Category: Anders, C]]
	[[Category: Higuchi, Y]]		[[Category: Higuchi, Y]]

OCA at 07:44, 8 November 2017

OCA — Wed, 08 Nov 2017 07:44:40 GMT

←Older revision		Revision as of 07:44, 8 November 2017
Line 3:		Line 3:
	<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://pdbe.org/3p1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://pdbe.org/3p1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>
	</table>		</table>
Line 29:		Line 30:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Anders, C]]		[[Category: Anders, C]]
	[[Category: Higuchi, Y]]		[[Category: Higuchi, Y]]

OCA at 10:59, 3 August 2017

OCA — Thu, 03 Aug 2017 10:59:16 GMT

←Older revision		Revision as of 10:59, 3 August 2017
Line 3:		Line 3:
	<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Human Human]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://pdbe.org/3p1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://pdbe.org/3p1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>
	</table>		</table>
Line 14:		Line 13:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[http://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>		[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[http://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Small-molecule stabilization of protein-protein interactions is an emerging field in chemical biology. We show how fusicoccanes, originally identified as fungal toxins acting on plants, promote the interaction of 14-3-3 proteins with the human potassium channel TASK-3 and present a semisynthetic fusicoccane derivative (FC-THF) that targets the 14-3-3 recognition motif (mode 3) in TASK-3. In the presence of FC-THF, the binding of 14-3-3 proteins to TASK-3 was increased 19-fold and protein crystallography provided the atomic details of the effects of FC-THF on this interaction. We also tested the functional effects of FC-THF on TASK channels heterologously expressed in Xenopus oocytes. Incubation with 10 muM FC-THF was found to promote the transport of TASK channels to the cell membrane, leading to a significantly higher density of channels at the surface membrane and increased potassium current.
		+
		+	A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface.,Anders C, Higuchi Y, Koschinsky K, Bartel M, Schumacher B, Thiel P, Nitta H, Preisig-Muller R, Schlichthorl G, Renigunta V, Ohkanda J, Daut J, Kato N, Ottmann C Chem Biol. 2013 Apr 18;20(4):583-93. doi: 10.1016/j.chembiol.2013.03.015. PMID:23601647<ref>PMID:23601647</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3p1p" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 21:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Human]]
	[[Category: Anders, C]]		[[Category: Anders, C]]
	[[Category: Higuchi, Y]]		[[Category: Higuchi, Y]]

OCA at 18:27, 4 August 2016

OCA — Thu, 04 Aug 2016 18:27:20 GMT

←Older revision		Revision as of 18:27, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide==		==Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide==
	<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>		<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://pdbe.org/3p1p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p1p ProSAT]</span></td></tr>
	</table>		</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] Intellectual deficit, Birk-Barel type. Birk-Barel mental retardation dysmorphism syndrome (BIBAS) [MIM:[http://omim.org/entry/612292 612292]]: A syndrome characterized by mental retardation, hypotonia, hyperactivity, and facial dysmorphism. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:18678320</ref>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.	+	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. [[http://www.uniprot.org/uniprot/KCNK9_HUMAN KCNK9_HUMAN]] pH-dependent, voltage-insensitive, background potassium channel protein.<ref>PMID:11042359</ref> <ref>PMID:11431495</ref>

	==See Also==		==See Also==
	*[[14-3-3 protein\|14-3-3 protein]]		*[[14-3-3 protein\|14-3-3 protein]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Anders, C]]		[[Category: Anders, C]]
	[[Category: Higuchi, Y]]		[[Category: Higuchi, Y]]

OCA at 18:12, 24 December 2014

OCA — Wed, 24 Dec 2014 18:12:05 GMT

←Older revision		Revision as of 18:12, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>		<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN]] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression.
		+
		+	==See Also==
		+	*[[14-3-3 protein\|14-3-3 protein]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Anders, C.]]	+	[[Category: Anders, C]]
-	[[Category: Higuchi, Y.]]	+	[[Category: Higuchi, Y]]
-	[[Category: Kato, N.]]	+	[[Category: Kato, N]]
-	[[Category: Ottmann, C.]]	+	[[Category: Ottmann, C]]
-	[[Category: Schumacher, B.]]	+	[[Category: Schumacher, B]]
-	[[Category: Thiel, P.]]	+	[[Category: Thiel, P]]
	[[Category: Adapter protein]]		[[Category: Adapter protein]]
	[[Category: Helical protein]]		[[Category: Helical protein]]

OCA at 10:45, 28 May 2014

OCA — Wed, 28 May 2014 10:45:13 GMT

←Older revision		Revision as of 10:45, 28 May 2014
Line 1:		Line 1:
-	~~[[Image:3p1p.png\|left\|200px]]~~	+	==Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide==
-		+	<StructureSection load='3p1p' size='340' side='right' caption='[[3p1p]], [[Resolution\|resolution]] 1.95Å' scene=''>
-	~~<!--~~	+	== Structural highlights ==
-	~~The line below this paragraph, containing "STRUCTURE_3p1p", creates the "Structure Box" on the page.~~	+	<table><tr><td colspan='2'>[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P1P FirstGlance]. <br>
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-	~~or leave the SCENE parameter empty for the default display.~~	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3iqu\|3iqu]], [[3lw1\|3lw1]], [[2o98\|2o98]], [[3p1n\|3p1n]], [[3p1o\|3p1o]], [[3p1q\|3p1q]], [[3p1r\|3p1r]], [[3p1s\|3p1s]]</td></tr>
-	~~-->~~	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SFN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-	~~{{STRUCTURE_3p1p\| PDB=3p1p \| SCENE= }}~~	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p1p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p1p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p1p RCSB], [http://www.ebi.ac.uk/pdbsum/3p1p PDBsum]</span></td></tr>
-		+	<table>
-	===Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide===	+	__TOC__
-		+	</StructureSection>
-		+
-	==~~About this Structure~~==	+
-	[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA].	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Anders, C.]]		[[Category: Anders, C.]]

OCA: Protected "3p1p" [edit=sysop:move=sysop]

OCA — Sun, 30 Oct 2011 09:35:28 GMT

Protected "3p1p" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:35, 30 October 2011

OCA at 09:35, 30 October 2011

OCA — Sun, 30 Oct 2011 09:35:22 GMT

←Older revision		Revision as of 09:35, 30 October 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3p1p.png\|left\|200px]]

-	The ~~entry 3p1p~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3p1p", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3p1p\| PDB=3p1p \| SCENE= }}

-	~~Authors: Anders, C., Higuchi, Y., Schumacher, B., Thiel, P., Kato, N., Ottmann, C.~~	+	===Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide===

-	Description: Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Nov 3 10~~:04:~~40 2010''~~	+	==About this Structure==
		+	[[3p1p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P1P OCA].
		+	[[Category: Homo sapiens]]
		+	[[Category: Anders, C.]]
		+	[[Category: Higuchi, Y.]]
		+	[[Category: Kato, N.]]
		+	[[Category: Ottmann, C.]]
		+	[[Category: Schumacher, B.]]
		+	[[Category: Thiel, P.]]
		+	[[Category: Adapter protein]]
		+	[[Category: Helical protein]]
		+	[[Category: Nucleus]]
		+	[[Category: Peptide binding protein]]
		+	[[Category: Phosphoprotein]]

OCA at 06:54, 3 November 2010

OCA — Wed, 03 Nov 2010 06:54:01 GMT

←Older revision		Revision as of 06:54, 3 November 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3p1p is ON HOLD	+	The entry 3p1p is ON HOLD until Paper Publication

	Authors: Anders, C., Higuchi, Y., Schumacher, B., Thiel, P., Kato, N., Ottmann, C.		Authors: Anders, C., Higuchi, Y., Schumacher, B., Thiel, P., Kato, N., Ottmann, C.
Line 7:		Line 7:
	Description: Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide		Description: Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Oct~~ ~~6 05~~:51:00 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 3 10:04:40 2010''