3p3o - Revision history

OCA at 10:38, 21 February 2024

OCA — Wed, 21 Feb 2024 10:38:17 GMT

←Older revision		Revision as of 10:38, 21 February 2024
Line 3:		Line 3:
	<StructureSection load='3p3o' size='340' side='right'caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>		<StructureSection load='3p3o' size='340' side='right'caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"streptomyces_thioluteus"_okami_1952 "streptomyces~~ thioluteus~~" okami 1952~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.54Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 "Streptomyces thioluteus" Okami 1952])</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [https://pdbe.org/3p3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [https://www.ebi.ac.uk/pdbsum/3p3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [https://pdbe.org/3p3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [https://www.ebi.ac.uk/pdbsum/3p3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3o ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q70KH6_STRTU Q70KH6_STRTU]
-	AurH is a unique cytochrome P450 monooxygenase catalyzing the stepwise formation of a homochiral oxygen heterocycle, a key structural and pharmacophoric component of the antibiotic aureothin. The exceptional enzymatic reaction involves a tandem oxygenation process including a regio- and stereospecific hydroxylation, followed by heterocyclization. For the structural and biochemical basis of this unparalleled sequence, four crystal structures of AurH variants in different conformational states and in complex with the P450 inhibitor ancymidol were solved, which represent the first structures of the CYP151A group. Structural data in conjunction with computational docking, site-directed mutagenesis, and chemical analyses unveiled a switch function when recognizing the two substrates, deoxyaureothin and the hydroxylated intermediate, thus allowing the second oxygenation-heterocyclization step. Furthermore, we were able to modify the chemo- and regioselectivity of AurH, yielding mutants that catalyze the regioselective six-electron transfer of a nonactivated methyl group to a carboxylic acid via hydroxyl and aldehyde intermediates.	+
-		+
-	~~Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase.,Zocher G, Richter ME, Mueller U, Hertweck C J Am Chem Soc. 2011 Jan 31. PMID~~:~~21280577<ref>PMID:21280577<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3p3o" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]		*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptomyces thioluteus okami 1952]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hertweck, C]]	+	[[Category: Streptomyces thioluteus]]
-	[[Category: Mueller, U]]	+	[[Category: Hertweck C]]
-	[[Category: Richter~~, M E.A~~]]	+	[[Category: Mueller U]]
-	[[Category: Zocher, G]]	+	[[Category: Richter MEA]]
-	~~[[Category: Cytochrome p450]]~~	+	[[Category: Zocher G]]
-	~~[[Category: Monooxygenase]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 11:17, 18 May 2022

OCA — Wed, 18 May 2022 11:17:30 GMT

←Older revision		Revision as of 11:17, 18 May 2022
Line 1:		Line 1:

	==Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus==		==Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus==
-	<StructureSection load='3p3o' size='340' side='right' caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>	+	<StructureSection load='3p3o' size='340' side='right'caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"streptomyces_thioluteus"_okami_1952 "streptomyces thioluteus" okami 1952]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3P3O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"streptomyces_thioluteus"_okami_1952 "streptomyces thioluteus" okami 1952]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 "Streptomyces thioluteus" Okami 1952])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 "Streptomyces thioluteus" Okami 1952])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [~~http~~://pdbe.org/3p3o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3p3o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [https://pdbe.org/3p3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [https://www.ebi.ac.uk/pdbsum/3p3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Cytochrome P450\|Cytochrome P450]]	+	*[[Cytochrome P450 3D structures\|Cytochrome P450 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Streptomyces thioluteus okami 1952]]		[[Category: Streptomyces thioluteus okami 1952]]
		+	[[Category: Large Structures]]
	[[Category: Hertweck, C]]		[[Category: Hertweck, C]]
	[[Category: Mueller, U]]		[[Category: Mueller, U]]

OCA at 04:06, 10 December 2016

OCA — Sat, 10 Dec 2016 04:06:40 GMT

←Older revision		Revision as of 04:06, 10 December 2016
Line 1:		Line 1:
		+
	==Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus==		==Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus==
	<StructureSection load='3p3o' size='340' side='right' caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>		<StructureSection load='3p3o' size='340' side='right' caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptomyces_thioluteus Streptomyces~~ thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P3O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"streptomyces_thioluteus"_okami_1952 "streptomyces thioluteus" okami 1952]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P3O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 Streptomyces thioluteus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 "Streptomyces thioluteus" Okami 1952])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [http://www.ebi.ac.uk/pdbsum/3p3o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [http://pdbe.org/3p3o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [http://www.ebi.ac.uk/pdbsum/3p3o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3p3o" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Streptomyces thioluteus]]	+	[[Category: Streptomyces thioluteus okami 1952]]
	[[Category: Hertweck, C]]		[[Category: Hertweck, C]]
	[[Category: Mueller, U]]		[[Category: Mueller, U]]

OCA at 11:22, 9 December 2014

OCA — Tue, 09 Dec 2014 11:22:04 GMT

←Older revision		Revision as of 11:22, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3p3o.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus==
		+	<StructureSection load='3p3o' size='340' side='right' caption='[[3p3o]], [[Resolution\|resolution]] 1.54Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3P3O FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3p3l\|3p3l]], [[3p3x\|3p3x]], [[3p3z\|3p3z]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aurH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66431 Streptomyces thioluteus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3p3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3p3o RCSB], [http://www.ebi.ac.uk/pdbsum/3p3o PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	AurH is a unique cytochrome P450 monooxygenase catalyzing the stepwise formation of a homochiral oxygen heterocycle, a key structural and pharmacophoric component of the antibiotic aureothin. The exceptional enzymatic reaction involves a tandem oxygenation process including a regio- and stereospecific hydroxylation, followed by heterocyclization. For the structural and biochemical basis of this unparalleled sequence, four crystal structures of AurH variants in different conformational states and in complex with the P450 inhibitor ancymidol were solved, which represent the first structures of the CYP151A group. Structural data in conjunction with computational docking, site-directed mutagenesis, and chemical analyses unveiled a switch function when recognizing the two substrates, deoxyaureothin and the hydroxylated intermediate, thus allowing the second oxygenation-heterocyclization step. Furthermore, we were able to modify the chemo- and regioselectivity of AurH, yielding mutants that catalyze the regioselective six-electron transfer of a nonactivated methyl group to a carboxylic acid via hydroxyl and aldehyde intermediates.

-	~~{{STRUCTURE_3p3o\| PDB=3p3o \| SCENE= }}~~	+	Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase.,Zocher G, Richter ME, Mueller U, Hertweck C J Am Chem Soc. 2011 Jan 31. PMID:21280577<ref>PMID:21280577</ref>

-	~~===Crystal Structure~~ of the ~~Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21280577}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3p3o]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].~~	+

	==See Also==		==See Also==
	*[[Cytochrome P450\|Cytochrome P450]]		*[[Cytochrome P450\|Cytochrome P450]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021280577<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Streptomyces thioluteus]]		[[Category: Streptomyces thioluteus]]
-	[[Category: Hertweck, C.]]	+	[[Category: Hertweck, C]]
-	[[Category: Mueller, U.]]	+	[[Category: Mueller, U]]
-	[[Category: Richter, M E.A.]]	+	[[Category: Richter, M E.A]]
-	[[Category: Zocher, G.]]	+	[[Category: Zocher, G]]
	[[Category: Cytochrome p450]]		[[Category: Cytochrome p450]]
	[[Category: Monooxygenase]]		[[Category: Monooxygenase]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 19:52, 20 October 2012

OCA — Sat, 20 Oct 2012 19:52:18 GMT

←Older revision		Revision as of 19:52, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3p3o]] is a 1 chain structure ~~of [[Cytochrome P450]]~~ with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].	+	[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].

	==See Also==		==See Also==

OCA at 08:44, 27 July 2012

OCA — Fri, 27 Jul 2012 08:44:34 GMT

←Older revision		Revision as of 08:44, 27 July 2012
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	[[Image:3p3o.png\|left\|200px]]		[[Image:3p3o.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3p3o\| PDB=3p3o \| SCENE= }}		{{STRUCTURE_3p3o\| PDB=3p3o \| SCENE= }}

	===Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus===		===Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21280577}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21280577 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21280577}}		{{ABSTRACT_PUBMED_21280577}}

	==About this Structure==		==About this Structure==
-	[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].	+	[[3p3o]] is a 1 chain structure of [[Cytochrome P450]] with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].
		+
		+	==See Also==
		+	*[[Cytochrome P450\|Cytochrome P450]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21280577~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021280577</ref><references group="xtra"/>
	[[Category: Streptomyces thioluteus]]		[[Category: Streptomyces thioluteus]]
	[[Category: Hertweck, C.]]		[[Category: Hertweck, C.]]
Line 28:		Line 20:
	[[Category: Richter, M E.A.]]		[[Category: Richter, M E.A.]]
	[[Category: Zocher, G.]]		[[Category: Zocher, G.]]
		+	[[Category: Cytochrome p450]]
		+	[[Category: Monooxygenase]]
		+	[[Category: Oxidoreductase]]

OCA at 06:17, 2 March 2011

OCA — Wed, 02 Mar 2011 06:17:12 GMT

←Older revision		Revision as of 06:17, 2 March 2011
Line 1:		Line 1:
-	[[Image:3p3o.~~jpg~~\|left\|200px]]	+	[[Image:3p3o.png\|left\|200px]]

	<!--		<!--

OCA at 05:40, 16 February 2011

OCA — Wed, 16 Feb 2011 05:40:40 GMT

←Older revision		Revision as of 05:40, 16 February 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3p3o.jpg\|left\|200px]]

-	The ~~entry 3p3o~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3p3o", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3p3o\| PDB=3p3o \| SCENE= }}

-	~~Authors: Zocher, G., Richter, M.E.A., Mueller, U., Hertweck, C.~~	+	===Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus===

-	~~Description: Crystal Structure of~~ the ~~Cytochrome P450 Monooxygenase AurH~~ (~~ntermII~~) from Streptomyces ~~Thioluteus~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21280577}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21280577 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21280577}}
		+
		+	==About this Structure==
		+	[[3p3o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_thioluteus Streptomyces thioluteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3O OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21280577</ref><references group="xtra"/>
		+	[[Category: Streptomyces thioluteus]]
		+	[[Category: Hertweck, C.]]
		+	[[Category: Mueller, U.]]
		+	[[Category: Richter, M E.A.]]
		+	[[Category: Zocher, G.]]

OCA: Protected "3p3o" [edit=sysop:move=sysop]

OCA — Wed, 19 Jan 2011 05:47:21 GMT

Protected "3p3o" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:47, 19 January 2011

OCA at 05:47, 19 January 2011

OCA — Wed, 19 Jan 2011 05:47:21 GMT

←Older revision		Revision as of 05:47, 19 January 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3p3o is ON HOLD	+	The entry 3p3o is ON HOLD until Paper Publication

	Authors: Zocher, G., Richter, M.E.A., Mueller, U., Hertweck, C.		Authors: Zocher, G., Richter, M.E.A., Mueller, U., Hertweck, C.

	Description: Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus		Description: Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:33:32 2010''