3pa9 - Revision history

OCA at 09:50, 6 September 2023

OCA — Wed, 06 Sep 2023 09:50:37 GMT

←Older revision		Revision as of 09:50, 6 September 2023
Line 3:		Line 3:
	<StructureSection load='3pa9' size='340' side='right'caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3pa9' size='340' side='right'caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.7Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3paa\|3paa]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [https://pdbe.org/3pa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [https://www.ebi.ac.uk/pdbsum/3pa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pa9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [https://pdbe.org/3pa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [https://www.ebi.ac.uk/pdbsum/3pa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pa9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D3H0F7_ECO44 D3H0F7_ECO44]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895]]~~	+	[[Category: Escherichia coli]]
-	~~[[Category: Aspartate transaminase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fu, M]]	+	[[Category: Fu M]]
-	[[Category: Liu, D]]	+	[[Category: Liu D]]
-	[[Category: Pozharski, E]]	+	[[Category: Pozharski E]]
-	[[Category: Ringe, D]]	+	[[Category: Ringe D]]
-	[[Category: Silverman~~, R B]]~~	+	[[Category: Silverman RB]]
-	~~[[Category: Catalytic lysine]]~~	+
-	~~[[Category: Plp]]~~	+
-	~~[[Category: Pmp]]~~	+
-	~~[[Category: Sadfa]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:31, 25 May 2022

OCA — Wed, 25 May 2022 08:31:28 GMT

←Older revision		Revision as of 08:31, 25 May 2022
Line 3:		Line 3:
	<StructureSection load='3pa9' size='340' side='right'caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3pa9' size='340' side='right'caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3paa\|3paa]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3paa\|3paa]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [~~http~~://pdbe.org/3pa9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3pa9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3pa9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [https://pdbe.org/3pa9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [https://www.ebi.ac.uk/pdbsum/3pa9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pa9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:31, 17 July 2019

OCA — Wed, 17 Jul 2019 11:31:53 GMT

←Older revision		Revision as of 11:31, 17 July 2019
Line 1:		Line 1:

	==Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5==		==Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5==
-	<StructureSection load='3pa9' size='340' side='right' caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='3pa9' size='340' side='right'caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Aspartate ~~Aminotransferase~~\|Aspartate ~~Aminotransferase~~]]	+	*[[Aspartate aminotransferase 3D structures\|Aspartate aminotransferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 27:
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Aspartate transaminase]]		[[Category: Aspartate transaminase]]
		+	[[Category: Large Structures]]
	[[Category: Fu, M]]		[[Category: Fu, M]]
	[[Category: Liu, D]]		[[Category: Liu, D]]

OCA at 03:50, 10 December 2016

OCA — Sat, 10 Dec 2016 03:50:22 GMT

←Older revision		Revision as of 03:50, 10 December 2016
Line 1:		Line 1:
		+
	==Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5==		==Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5==
	<StructureSection load='3pa9' size='340' side='right' caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3pa9' size='340' side='right' caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3paa\|3paa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3paa\|3paa]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [http://www.ebi.ac.uk/pdbsum/3pa9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [http://pdbe.org/3pa9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [http://www.ebi.ac.uk/pdbsum/3pa9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3pa9 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3pa9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Aspartate transaminase]]		[[Category: Aspartate transaminase]]
-	[[Category: Escherichia coli]]
	[[Category: Fu, M]]		[[Category: Fu, M]]
	[[Category: Liu, D]]		[[Category: Liu, D]]

OCA at 13:12, 9 December 2014

OCA — Tue, 09 Dec 2014 13:12:07 GMT

←Older revision		Revision as of 13:12, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3pa9.~~png~~\|~~left~~\|~~200px~~]]	+	==Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5==
		+	<StructureSection load='3pa9' size='340' side='right' caption='[[3pa9]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PA9 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PJ7:4-AMINOFURAN-2-CARBOXYLIC+ACID'>PJ7</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3paa\|3paa]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aspartate_transaminase Aspartate transaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.1 2.6.1.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pa9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pa9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pa9 RCSB], [http://www.ebi.ac.uk/pdbsum/3pa9 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	As a potential drug to treat neurological diseases, the mechanism-based inhibitor (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) has been found to inhibit the gamma-aminobutyric acid aminotransferase (GABA-AT) reaction. To circumvent the difficulties in structural studies of a S-ADFA-enzyme complex using GABA-AT, l-aspartate aminotransferase (l-AspAT) from Escherichia coli was used as a model PLP-dependent enzyme. Crystal structures of the E. coli aspartate aminotransferase with S-ADFA bound to the active site were obtained via cocrystallization at pH 7.5 and 8. The complex structures suggest that S-ADFA inhibits the transamination reaction by forming adducts with the catalytic lysine 246 via a covalent bond while producing 1 equiv of pyridoxamine 5'-phosphate (PMP). Based on the structures, formation of the K246-S-ADFA adducts requires a specific initial binding configuration of S-ADFA in the l-AspAT active site, as well as deprotonation of the epsilon-amino group of lysine 246 after the formation of the quinonoid and/or ketimine intermediate in the overall inactivation reaction.

-	~~{{STRUCTURE_3pa9\| PDB=3pa9 \| SCENE= }}~~	+	Mechanism of Inactivation of Escherichia coli Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-furancarboxylic Acid .,Liu D, Pozharski E, Fu M, Silverman RB, Ringe D Biochemistry. 2010 Nov 15. PMID:21033689<ref>PMID:21033689</ref>

-	~~===Mechanism~~ of ~~inactivation of E~~. ~~coli aspartate aminotransferase by (~~S~~)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7~~.~~5===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_21033689}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3pa9]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].~~	+

	==See Also==		==See Also==
	*[[Aspartate Aminotransferase\|Aspartate Aminotransferase]]		*[[Aspartate Aminotransferase\|Aspartate Aminotransferase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021033689<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Aspartate transaminase]]		[[Category: Aspartate transaminase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Fu, M.]]	+	[[Category: Fu, M]]
-	[[Category: Liu, D.]]	+	[[Category: Liu, D]]
-	[[Category: Pozharski, E.]]	+	[[Category: Pozharski, E]]
-	[[Category: Ringe, D.]]	+	[[Category: Ringe, D]]
-	[[Category: Silverman, R B.]]	+	[[Category: Silverman, R B]]
	[[Category: Catalytic lysine]]		[[Category: Catalytic lysine]]
	[[Category: Plp]]		[[Category: Plp]]

OCA at 16:23, 20 October 2012

OCA — Sat, 20 Oct 2012 16:23:58 GMT

←Older revision		Revision as of 16:23, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3pa9]] is a 1 chain structure ~~of [[Aspartate Aminotransferase]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].	+	[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].

	==See Also==		==See Also==

OCA at 21:32, 26 July 2012

OCA — Thu, 26 Jul 2012 21:32:58 GMT

←Older revision		Revision as of 21:32, 26 July 2012
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	[[Image:3pa9.png\|left\|200px]]		[[Image:3pa9.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3pa9", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3pa9\| PDB=3pa9 \| SCENE= }}		{{STRUCTURE_3pa9\| PDB=3pa9 \| SCENE= }}

	===Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5===		===Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21033689}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21033689 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21033689}}		{{ABSTRACT_PUBMED_21033689}}

	==About this Structure==		==About this Structure==
-	[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].	+	[[3pa9]] is a 1 chain structure of [[Aspartate Aminotransferase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].
		+
		+	==See Also==
		+	*[[Aspartate Aminotransferase\|Aspartate Aminotransferase]]

	==Reference==		==Reference==
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	[[Category: Ringe, D.]]		[[Category: Ringe, D.]]
	[[Category: Silverman, R B.]]		[[Category: Silverman, R B.]]
		+	[[Category: Catalytic lysine]]
		+	[[Category: Plp]]
		+	[[Category: Pmp]]
		+	[[Category: Sadfa]]
		+	[[Category: Transferase]]

OCA: Protected "3pa9" [edit=sysop:move=sysop]

OCA — Thu, 12 May 2011 03:58:01 GMT

Protected "3pa9" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:58, 12 May 2011

OCA at 03:57, 12 May 2011

OCA — Thu, 12 May 2011 03:57:59 GMT

←Older revision		Revision as of 03:57, 12 May 2011
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-	~~{{Seed}}~~	+	[[Image:3pa9.png\|left\|200px]]
-	[[Image:3pa9.~~jpg~~\|left\|200px]]	+

	<!--		<!--
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	==About this Structure==		==About this Structure==
-	~~3PA9~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].	+	[[3pa9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~21033689~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:021033689</ref><references group="xtra"/>
	[[Category: Aspartate transaminase]]		[[Category: Aspartate transaminase]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
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	[[Category: Ringe, D.]]		[[Category: Ringe, D.]]
	[[Category: Silverman, R B.]]		[[Category: Silverman, R B.]]
-	[[Category: Catalytic lysine]]
-	[[Category: Plp]]
-	[[Category: Pmp]]
-	[[Category: Sadfa]]
-	[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:35:21 2010''

OCA at 08:23, 1 December 2010

OCA — Wed, 01 Dec 2010 08:23:35 GMT

←Older revision		Revision as of 08:23, 1 December 2010
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-	~~'''Unreleased structure'''~~	+	{{Seed}}
		+	[[Image:3pa9.jpg\|left\|200px]]

-	The ~~entry 3pa9~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3pa9", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3pa9\| PDB=3pa9 \| SCENE= }}

-	~~Authors: Liu, D., Pozharski,~~ E., ~~Fu, M., Silverman, R.B., Ringe, D~~.	+	===Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5===

-	Description: Mechanism of inactivation of E. coli aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-furancarboxylic acid (S-ADFA) pH 7.5

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Nov 24 13~~:57:20 2010''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21033689}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21033689 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21033689}}
		+
		+	==About this Structure==
		+	3PA9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PA9 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:21033689</ref><references group="xtra"/>
		+	[[Category: Aspartate transaminase]]
		+	[[Category: Escherichia coli]]
		+	[[Category: Fu, M.]]
		+	[[Category: Liu, D.]]
		+	[[Category: Pozharski, E.]]
		+	[[Category: Ringe, D.]]
		+	[[Category: Silverman, R B.]]
		+	[[Category: Catalytic lysine]]
		+	[[Category: Plp]]
		+	[[Category: Pmp]]
		+	[[Category: Sadfa]]
		+	[[Category: Transferase]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 1 11:35:21 2010''