3prs - Revision history

OCA at 09:59, 6 September 2023

OCA — Wed, 06 Sep 2023 09:59:56 GMT

←Older revision		Revision as of 09:59, 6 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3prs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PRS FirstGlance]. <br>		<table><tr><td colspan='2'>[[3prs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PRS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.38Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [https://pdbe.org/3prs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [https://www.ebi.ac.uk/pdbsum/3prs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3prs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [https://pdbe.org/3prs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [https://www.ebi.ac.uk/pdbsum/3prs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3prs ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CARP_CRYPA CARP_CRYPA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
-	[[Category: Endothiapepsin]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Heine, A]]	+	[[Category: Heine A]]
-	[[Category: Klebe, G]]	+	[[Category: Klebe G]]
-	[[Category: Koester, H]]	+	[[Category: Koester H]]
-	~~[[Category: Hydrolase-hydrolase inhibitor complex~~]]	+

OCA at 08:52, 25 May 2022

OCA — Wed, 25 May 2022 08:52:06 GMT

←Older revision		Revision as of 08:52, 25 May 2022
Line 1:		Line 1:

	==Endothiapepsin in complex with ritonavir==		==Endothiapepsin in complex with ritonavir==
-	<StructureSection load='3prs' size='340' side='right' caption='[[3prs]], [[Resolution\|resolution]] 1.38Å' scene=''>	+	<StructureSection load='3prs' size='340' side='right'caption='[[3prs]], [[Resolution\|resolution]] 1.38Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3prs]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3PRS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3prs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PRS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [~~http~~://pdbe.org/3prs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3prs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3prs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [https://pdbe.org/3prs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [https://www.ebi.ac.uk/pdbsum/3prs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3prs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	[[Category: Endothiapepsin]]		[[Category: Endothiapepsin]]
		+	[[Category: Large Structures]]
	[[Category: Heine, A]]		[[Category: Heine, A]]
	[[Category: Klebe, G]]		[[Category: Klebe, G]]
	[[Category: Koester, H]]		[[Category: Koester, H]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 11:28, 10 December 2016

OCA — Sat, 10 Dec 2016 11:28:55 GMT

←Older revision		Revision as of 11:28, 10 December 2016
Line 1:		Line 1:
		+
	==Endothiapepsin in complex with ritonavir==		==Endothiapepsin in complex with ritonavir==
	<StructureSection load='3prs' size='340' side='right' caption='[[3prs]], [[Resolution\|resolution]] 1.38Å' scene=''>		<StructureSection load='3prs' size='340' side='right' caption='[[3prs]], [[Resolution\|resolution]] 1.38Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [http://www.ebi.ac.uk/pdbsum/3prs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [http://pdbe.org/3prs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [http://www.ebi.ac.uk/pdbsum/3prs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3prs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3prs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 13:42, 9 December 2014

OCA — Tue, 09 Dec 2014 13:42:46 GMT

←Older revision		Revision as of 13:42, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3prs.~~png~~\|~~left\|200px~~]]	+	==Endothiapepsin in complex with ritonavir==
		+	<StructureSection load='3prs' size='340' side='right' caption='[[3prs]], [[Resolution\|resolution]] 1.38Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PRS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=RIT:RITONAVIR'>RIT</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endothiapepsin Endothiapepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.22 3.4.23.22] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3prs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3prs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3prs RCSB], [http://www.ebi.ac.uk/pdbsum/3prs PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Small highly soluble probe molecules such as aniline, urea, N-methylurea, 2-bromoacetate, 1,2-propanediol, nitrous oxide, benzamidine, and phenol were soaked into crystals of various proteins to map their binding pockets and to detect hot spots of binding with respect to hydrophobic and hydrophilic properties. The selected probe molecules were first tested at the zinc protease thermolysin. They were then applied to a wider range of proteins such as protein kinase A, D-xylose isomerase, 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, endothiapepsin, and secreted aspartic protease 2. The crystal structures obtained clearly show that the probe molecules populate the protein binding pockets in an ordered fashion. The thus characterized, experimentally observed hot spots of binding were subjected to computational active site mapping using HotspotsX. This approach uses knowledge-based pair potentials to detect favorable binding positions for various atom types. Good agreement between the in silico hot spot predictions and the experimentally observed positions of the polar hydrogen bond forming functional groups and hydrophobic portions was obtained. Finally, we compared the observed poses of the small-molecule probes with those of much larger structurally related ligands. They coincide remarkably well with the larger ligands, considering their spatial orientation and the experienced interaction patterns. This observation confirms the fundamental hypothesis of fragment-based lead discovery: that binding poses, even of very small molecular probes, do not significantly deviate or move once a ligand is grown further into the binding site. This underscores the fact that these probes populate given hot spots and can be regarded as relevant seeds for further design.

-	~~{{STRUCTURE_3prs\| PDB=3prs \| SCENE= }}~~	+	Experimental and Computational Active Site Mapping as a Starting Point to Fragment-Based Lead Discovery.,Behnen J, Koster H, Neudert G, Craan T, Heine A, Klebe G ChemMedChem. 2011 Dec 23. doi: 10.1002/cmdc.201100490. PMID:22213702<ref>PMID:22213702</ref>

-	~~===Endothiapepsin in complex with ritonavir===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22213702}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3prs]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].~~	+

	==See Also==		==See Also==
	*[[Pepsin\|Pepsin]]		*[[Pepsin\|Pepsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022213702<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	[[Category: Endothiapepsin]]		[[Category: Endothiapepsin]]
-	[[Category: Heine, A.]]	+	[[Category: Heine, A]]
-	[[Category: Klebe, G.]]	+	[[Category: Klebe, G]]
-	[[Category: Koester, H.]]	+	[[Category: Koester, H]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 11:41, 20 October 2012

OCA — Sat, 20 Oct 2012 11:41:54 GMT

←Older revision		Revision as of 11:41, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3prs]] is a 1 chain structure ~~of [[Pepsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].	+	[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].

	==See Also==		==See Also==

OCA at 06:17, 26 July 2012

OCA — Thu, 26 Jul 2012 06:17:34 GMT

←Older revision		Revision as of 06:17, 26 July 2012
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	[[Image:3prs.png\|left\|200px]]		[[Image:3prs.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_3prs\| PDB=3prs \| SCENE= }}		{{STRUCTURE_3prs\| PDB=3prs \| SCENE= }}

	===Endothiapepsin in complex with ritonavir===		===Endothiapepsin in complex with ritonavir===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22213702}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22213702 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_22213702}}		{{ABSTRACT_PUBMED_22213702}}

	==About this Structure==		==About this Structure==
-	[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].	+	[[3prs]] is a 1 chain structure of [[Pepsin]] with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].
		+
		+	==See Also==
		+	*[[Pepsin\|Pepsin]]

	==Reference==		==Reference==

OCA at 05:38, 8 February 2012

OCA — Wed, 08 Feb 2012 05:38:29 GMT

←Older revision		Revision as of 05:38, 8 February 2012
Line 11:		Line 11:
	===Endothiapepsin in complex with ritonavir===		===Endothiapepsin in complex with ritonavir===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22213702}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22213702 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22213702}}

	==About this Structure==		==About this Structure==
	[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].		[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022213702</ref><references group="xtra"/>
	[[Category: Cryphonectria parasitica]]		[[Category: Cryphonectria parasitica]]
	[[Category: Endothiapepsin]]		[[Category: Endothiapepsin]]

OCA: Protected "3prs" [edit=sysop:move=sysop]

OCA — Sun, 30 Oct 2011 11:22:17 GMT

Protected "3prs" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:22, 30 October 2011

OCA at 11:22, 30 October 2011

OCA — Sun, 30 Oct 2011 11:22:12 GMT

←Older revision		Revision as of 11:22, 30 October 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3prs.png\|left\|200px]]

-	The ~~entry 3prs~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3prs", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3prs\| PDB=3prs \| SCENE= }}

-	~~Authors: Koester, H., Heine, A., Klebe, G.~~	+	===Endothiapepsin in complex with ritonavir===

-	Description: Endothiapepsin in complex with ritonavir

-	~~''Page seeded by~~ [http://oca.weizmann.ac.il/oca OCA ] ~~on Wed Dec 22 09~~:37:~~06 2010''~~	+	==About this Structure==
		+	[[3prs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryphonectria_parasitica Cryphonectria parasitica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PRS OCA].
		+	[[Category: Cryphonectria parasitica]]
		+	[[Category: Endothiapepsin]]
		+	[[Category: Heine, A.]]
		+	[[Category: Klebe, G.]]
		+	[[Category: Koester, H.]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]

OCA at 06:24, 22 December 2010

OCA — Wed, 22 Dec 2010 06:24:30 GMT

←Older revision		Revision as of 06:24, 22 December 2010
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3prs is ON HOLD	+	The entry 3prs is ON HOLD until Paper Publication

	Authors: Koester, H., Heine, A., Klebe, G.		Authors: Koester, H., Heine, A., Klebe, G.
Line 7:		Line 7:
	Description: Endothiapepsin in complex with ritonavir		Description: Endothiapepsin in complex with ritonavir

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec ~~8 11~~:33:22 2010''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:37:06 2010''