3q2o - Revision history

OCA at 11:31, 14 March 2024

OCA — Thu, 14 Mar 2024 11:31:02 GMT

←Older revision		Revision as of 11:31, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3q2o' size='340' side='right'caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='3q2o' size='340' side='right'caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bacaa Bacaa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis_str._A0248 Bacillus anthracis str. A0248]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.96Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>BAA_0344, purK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~592021 BACAA])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>[https://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [https://pdbe.org/3q2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [https://www.ebi.ac.uk/pdbsum/3q2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [https://pdbe.org/3q2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [https://www.ebi.ac.uk/pdbsum/3q2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2o ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The apo structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis (baPurK) with Mg2+ in the active site is reported at 1.96 A resolution. PurK is an enzyme in the purine-biosynthetic pathway, unique to prokaryotes, that converts 5-aminoimidazole ribonucleotide to N5-carboxyaminoimidazole ribonucleotide and has been suggested as a potential antimicrobial drug target. Two interesting features of baPurK are a flexible B-loop (residues 149/150-157) that is in close contact with the active site and the binding of Mg2+ to the active site without additional ligands.
-
-	Structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis.,Tuntland ML, Johnson ME, Fung LW, Santarsiero BD Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):870-4. Epub 2011, Sep 8. PMID:21931218<ref>PMID:21931218</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3q2o" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Phosphoribosylaminoimidazole carboxylase 3D structures\|Phosphoribosylaminoimidazole carboxylase 3D structures]]		*[[Phosphoribosylaminoimidazole carboxylase 3D structures\|Phosphoribosylaminoimidazole carboxylase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacaa~~]]	+	[[Category: Bacillus anthracis str. A0248]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Phosphoribosylaminoimidazole carboxylase]]~~	+	[[Category: Fung LW]]
-	[[Category: Fung~~, L W~~]]	+	[[Category: Johnson ME]]
-	[[Category: Johnson~~, M E~~]]	+	[[Category: Santarsiero BD]]
-	[[Category: Santarsiero~~, B D~~]]	+	[[Category: Tuntland ML]]
-	[[Category: Tuntland~~, M L]]~~	+
-	~~[[Category: Atp binding]]~~	+
-	~~[[Category: Carboxylase]]~~	+
-	~~[[Category: Carboxylate]]~~	+
-	~~[[Category: Lyase~~]]	+

OCA at 05:49, 8 June 2022

OCA — Wed, 08 Jun 2022 05:49:21 GMT

←Older revision		Revision as of 05:49, 8 June 2022
Line 1:		Line 1:

	==Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase==		==Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase==
-	<StructureSection load='3q2o' size='340' side='right' caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>	+	<StructureSection load='3q2o' size='340' side='right'caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacaa Bacaa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacaa Bacaa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=592021 BACAA])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=592021 BACAA])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [~~http~~://pdbe.org/3q2o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3q2o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2o ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [https://pdbe.org/3q2o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [https://www.ebi.ac.uk/pdbsum/3q2o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Phosphoribosylaminoimidazole carboxylase\|Phosphoribosylaminoimidazole carboxylase]]	+	*[[Phosphoribosylaminoimidazole carboxylase 3D structures\|Phosphoribosylaminoimidazole carboxylase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Bacaa]]		[[Category: Bacaa]]
		+	[[Category: Large Structures]]
	[[Category: Phosphoribosylaminoimidazole carboxylase]]		[[Category: Phosphoribosylaminoimidazole carboxylase]]
	[[Category: Fung, L W]]		[[Category: Fung, L W]]

OCA at 17:49, 5 August 2016

OCA — Fri, 05 Aug 2016 17:49:59 GMT

←Older revision		Revision as of 17:49, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase==		==Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase==
	<StructureSection load='3q2o' size='340' side='right' caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>		<StructureSection load='3q2o' size='340' side='right' caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_anthracis Bacillus anthracis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacaa Bacaa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1392 Bacillus anthracis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=592021 BACAA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [http://www.ebi.ac.uk/pdbsum/3q2o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [http://pdbe.org/3q2o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [http://www.ebi.ac.uk/pdbsum/3q2o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3q2o ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3q2o" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Phosphoribosylaminoimidazole carboxylase\|Phosphoribosylaminoimidazole carboxylase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus anthracis~~]]	+	[[Category: Bacaa]]
	[[Category: Phosphoribosylaminoimidazole carboxylase]]		[[Category: Phosphoribosylaminoimidazole carboxylase]]
	[[Category: Fung, L W]]		[[Category: Fung, L W]]

OCA at 23:12, 3 January 2015

OCA — Sat, 03 Jan 2015 23:12:17 GMT

←Older revision		Revision as of 23:12, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>		<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [http://www.ebi.ac.uk/pdbsum/3q2o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [http://www.ebi.ac.uk/pdbsum/3q2o PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 14:
	Structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis.,Tuntland ML, Johnson ME, Fung LW, Santarsiero BD Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):870-4. Epub 2011, Sep 8. PMID:21931218<ref>PMID:21931218</ref>		Structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis.,Tuntland ML, Johnson ME, Fung LW, Santarsiero BD Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):870-4. Epub 2011, Sep 8. PMID:21931218<ref>PMID:21931218</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 22:
	[[Category: Bacillus anthracis]]		[[Category: Bacillus anthracis]]
	[[Category: Phosphoribosylaminoimidazole carboxylase]]		[[Category: Phosphoribosylaminoimidazole carboxylase]]
-	[[Category: Fung, L W.]]	+	[[Category: Fung, L W]]
-	[[Category: Johnson, M E.]]	+	[[Category: Johnson, M E]]
-	[[Category: Santarsiero, B D.]]	+	[[Category: Santarsiero, B D]]
-	[[Category: Tuntland, M L.]]	+	[[Category: Tuntland, M L]]
	[[Category: Atp binding]]		[[Category: Atp binding]]
	[[Category: Carboxylase]]		[[Category: Carboxylase]]
	[[Category: Carboxylate]]		[[Category: Carboxylate]]
	[[Category: Lyase]]		[[Category: Lyase]]

OCA at 05:27, 4 June 2014

OCA — Wed, 04 Jun 2014 05:27:40 GMT

←Older revision		Revision as of 05:27, 4 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3q2o.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase==
		+	<StructureSection load='3q2o' size='340' side='right' caption='[[3q2o]], [[Resolution\|resolution]] 1.96Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3Q2O FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAA_0344, purK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1392 Bacillus anthracis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3q2o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q2o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3q2o RCSB], [http://www.ebi.ac.uk/pdbsum/3q2o PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The apo structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis (baPurK) with Mg2+ in the active site is reported at 1.96 A resolution. PurK is an enzyme in the purine-biosynthetic pathway, unique to prokaryotes, that converts 5-aminoimidazole ribonucleotide to N5-carboxyaminoimidazole ribonucleotide and has been suggested as a potential antimicrobial drug target. Two interesting features of baPurK are a flexible B-loop (residues 149/150-157) that is in close contact with the active site and the binding of Mg2+ to the active site without additional ligands.

-	<!--	+	Structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis.,Tuntland ML, Johnson ME, Fung LW, Santarsiero BD Acta Crystallogr D Biol Crystallogr. 2011 Oct;67(Pt 10):870-4. Epub 2011, Sep 8. PMID:21931218<ref>PMID:21931218</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3q2o"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded~~),	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3q2o\| PDB=3q2o \| SCENE= }}~~	+

-	~~===Crystal Structure~~ of ~~purK: N5-carboxyaminoimidazole ribonucleotide synthetase===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21931218}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21931218 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21931218}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3q2o]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021931218<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus anthracis]]		[[Category: Bacillus anthracis]]
	[[Category: Phosphoribosylaminoimidazole carboxylase]]		[[Category: Phosphoribosylaminoimidazole carboxylase]]

OCA at 09:26, 30 October 2011

OCA — Sun, 30 Oct 2011 09:26:56 GMT

←Older revision		Revision as of 09:26, 30 October 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3q2o.png\|left\|200px]]

-	The ~~entry 3q2o~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3q2o", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3q2o\| PDB=3q2o \| SCENE= }}

-	~~Authors~~: ~~Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E.~~	+	===Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase===

-	~~Description~~: ~~Crystal~~ Structure ~~of purK~~: N5-~~carboxyaminoimidazole ribonucleotide synthetase~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21931218}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21931218 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21931218}}
		+
		+	==About this Structure==
		+	[[3q2o]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q2O OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021931218</ref><references group="xtra"/>
		+	[[Category: Bacillus anthracis]]
		+	[[Category: Phosphoribosylaminoimidazole carboxylase]]
		+	[[Category: Fung, L W.]]
		+	[[Category: Johnson, M E.]]
		+	[[Category: Santarsiero, B D.]]
		+	[[Category: Tuntland, M L.]]
		+	[[Category: Atp binding]]
		+	[[Category: Carboxylase]]
		+	[[Category: Carboxylate]]
		+	[[Category: Lyase]]

OCA at 05:50, 19 January 2011

OCA — Wed, 19 Jan 2011 05:50:20 GMT

←Older revision		Revision as of 05:50, 19 January 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3q2o is ON HOLD	+	The entry 3q2o is ON HOLD until Paper Publication

	Authors: Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E.		Authors: Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E.

	Description: Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase		Description: Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase

OCA: Protected "3q2o" [edit=sysop:move=sysop]

OCA — Wed, 29 Dec 2010 18:17:36 GMT

Protected "3q2o" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:17, 29 December 2010

OCA: New page: '''Unreleased structure''' The entry 3q2o is ON HOLD Authors: Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E. Description: Crystal Structure of purK: N5-carboxyaminoimidaz...

OCA — Wed, 29 Dec 2010 18:17:35 GMT

New page: '''Unreleased structure''' The entry 3q2o is ON HOLD Authors: Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E. Description: Crystal Structure of purK: N5-carboxyaminoimidaz...

New page

'''Unreleased structure'''

The entry 3q2o is ON HOLD

Authors: Fung, L.W., Tuntland, M.L., Santarsiero, B.D., Johnson, M.E.

Description: Crystal Structure of purK: N5-carboxyaminoimidazole ribonucleotide synthetase