3qrb - Revision history

OCA at 11:55, 14 March 2024

OCA — Thu, 14 Mar 2024 11:55:42 GMT

←Older revision		Revision as of 11:55, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3qrb' size='340' side='right'caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3qrb' size='340' side='right'caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [https://pdbe.org/3qrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [https://www.ebi.ac.uk/pdbsum/3qrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [https://pdbe.org/3qrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [https://www.ebi.ac.uk/pdbsum/3qrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).	+	[https://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Cell adhesion by classical cadherins is mediated by dimerization of their EC1 domains through the 'swapping' of N-terminal beta-strands. We use molecular simulations, measurements of binding affinities and X-ray crystallography to provide a detailed picture of the structural and energetic factors that control the adhesive dimerization of cadherins. We show that strand swapping in EC1 is driven by conformational strain in cadherin monomers that arises from the anchoring of their short N-terminal strand at one end by the conserved Trp2 and at the other by ligation to Ca(2+) ions. We also demonstrate that a conserved proline-proline motif functions to avoid the formation of an overly tight interface where affinity differences between different cadherins, crucial at the cellular level, are lost. We use these findings to design site-directed mutations that transform a monomeric EC2-EC3 domain cadherin construct into a strand-swapped dimer.	+
-		+
-	Molecular design principles underlying beta-strand swapping in the adhesive dimerization of cadherins.,Vendome J, Posy S, Jin X, Bahna F, Ahlsen G, Shapiro L, Honig B Nat Struct Mol Biol. 2011 Jun;18(6):693-700. doi: 10.1038/nsmb.2051. Epub 2011, May 15. PMID:21572446<ref>PMID:21572446</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3qrb" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[Cadherin 3D structures\|Cadherin 3D structures]]		*[[Cadherin 3D structures\|Cadherin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Jin, X]]	+	[[Category: Jin X]]
-	[[Category: Shapiro, L]]	+	[[Category: Shapiro L]]
-	~~[[Category: Cadherin]]~~	+
-	~~[[Category: Cell adhesion~~]]	+

OCA at 06:20, 8 June 2022

OCA — Wed, 08 Jun 2022 06:20:45 GMT

←Older revision		Revision as of 06:20, 8 June 2022
Line 1:		Line 1:
		+
	==crystal structure of E-cadherin EC1-2 P5A P6A==		==crystal structure of E-cadherin EC1-2 P5A P6A==
-	<StructureSection load='3qrb' size='340' side='right' caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3qrb' size='340' side='right'caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3QRB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QRB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [~~http~~://pdbe.org/3qrb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [https://pdbe.org/3qrb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [https://www.ebi.ac.uk/pdbsum/3qrb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qrb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).	+	[[https://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 21:

	==See Also==		==See Also==
-	*[[Cadherin\|Cadherin]]	+	*[[Cadherin 3D structures\|Cadherin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Jin, X]]		[[Category: Jin, X]]

OCA at 07:13, 9 December 2015

OCA — Wed, 09 Dec 2015 07:13:06 GMT

←Older revision		Revision as of 07:13, 9 December 2015
Line 2:		Line 2:
	<StructureSection load='3qrb' size='340' side='right' caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3qrb' size='340' side='right' caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QRB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QRB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 ~~Mus musculus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://pdbe.org/3qrb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).		[[http://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cell adhesion by classical cadherins is mediated by dimerization of their EC1 domains through the 'swapping' of N-terminal beta-strands. We use molecular simulations, measurements of binding affinities and X-ray crystallography to provide a detailed picture of the structural and energetic factors that control the adhesive dimerization of cadherins. We show that strand swapping in EC1 is driven by conformational strain in cadherin monomers that arises from the anchoring of their short N-terminal strand at one end by the conserved Trp2 and at the other by ligation to Ca(2+) ions. We also demonstrate that a conserved proline-proline motif functions to avoid the formation of an overly tight interface where affinity differences between different cadherins, crucial at the cellular level, are lost. We use these findings to design site-directed mutations that transform a monomeric EC2-EC3 domain cadherin construct into a strand-swapped dimer.
		+
		+	Molecular design principles underlying beta-strand swapping in the adhesive dimerization of cadherins.,Vendome J, Posy S, Jin X, Bahna F, Ahlsen G, Shapiro L, Honig B Nat Struct Mol Biol. 2011 Jun;18(6):693-700. doi: 10.1038/nsmb.2051. Epub 2011, May 15. PMID:21572446<ref>PMID:21572446</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3qrb" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Cadherin\|Cadherin]]		*[[Cadherin\|Cadherin]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Jin, X]]		[[Category: Jin, X]]
	[[Category: Shapiro, L]]		[[Category: Shapiro, L]]
	[[Category: Cadherin]]		[[Category: Cadherin]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 05:33, 25 December 2014

OCA — Thu, 25 Dec 2014 05:33:20 GMT

←Older revision		Revision as of 05:33, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CADH1_MOUSE CADH1_MOUSE]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 (By similarity). E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production (By similarity).

	==See Also==		==See Also==

OCA at 13:11, 9 December 2014

OCA — Tue, 09 Dec 2014 13:11:37 GMT

←Older revision		Revision as of 13:11, 9 December 2014
Line 1:		Line 1:
-	~~[[Image:3qrb.png\|left\|200px]]~~	+	==crystal structure of E-cadherin EC1-2 P5A P6A==
-		+	<StructureSection load='3qrb' size='340' side='right' caption='[[3qrb]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~{{STRUCTURE_3qrb\| PDB=3qrb \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QRB FirstGlance]. <br>
-	===crystal structure of E-cadherin EC1-2 P5A P6A===	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Cdh1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qrb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qrb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qrb RCSB], [http://www.ebi.ac.uk/pdbsum/3qrb PDBsum]</span></td></tr>
-	==~~About this Structure~~==	+	</table>
-	[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].	+

	==See Also==		==See Also==
	*[[Cadherin\|Cadherin]]		*[[Cadherin\|Cadherin]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Jin, X.]]	+	[[Category: Jin, X]]
-	[[Category: Shapiro, L.]]	+	[[Category: Shapiro, L]]
	[[Category: Cadherin]]		[[Category: Cadherin]]
	[[Category: Cell adhesion]]		[[Category: Cell adhesion]]

OCA at 13:12, 20 October 2012

OCA — Sat, 20 Oct 2012 13:12:33 GMT

←Older revision		Revision as of 13:12, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3qrb]] is a 2 chain structure ~~of [[Cadherin]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].	+	[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].

	==See Also==		==See Also==

OCA at 11:14, 26 July 2012

OCA — Thu, 26 Jul 2012 11:14:28 GMT

←Older revision		Revision as of 11:14, 26 July 2012
Line 1:		Line 1:
-	[[Image:3qrb.~~jpg~~\|left\|200px]]	+	[[Image:3qrb.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3qrb", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3qrb\| PDB=3qrb \| SCENE= }}		{{STRUCTURE_3qrb\| PDB=3qrb \| SCENE= }}

Line 13:		Line 7:

	==About this Structure==		==About this Structure==
-	[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].	+	[[3qrb]] is a 2 chain structure of [[Cadherin]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].
		+
		+	==See Also==
		+	*[[Cadherin\|Cadherin]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Jin, X.]]		[[Category: Jin, X.]]
	[[Category: Shapiro, L.]]		[[Category: Shapiro, L.]]
		+	[[Category: Cadherin]]
		+	[[Category: Cell adhesion]]

OCA at 05:55, 18 May 2011

OCA — Wed, 18 May 2011 05:55:04 GMT

←Older revision		Revision as of 05:55, 18 May 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3qrb.jpg\|left\|200px]]

-	The ~~entry 3qrb~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3qrb", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3qrb\| PDB=3qrb \| SCENE= }}

-	~~Authors: Jin, X., Shapiro, L.~~	+	===crystal structure of E-cadherin EC1-2 P5A P6A===

-	~~Description: crystal~~ structure ~~of E~~-~~cadherin EC1-2 P5A P6A~~	+
		+	==About this Structure==
		+	[[3qrb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QRB OCA].
		+	[[Category: Mus musculus]]
		+	[[Category: Jin, X.]]
		+	[[Category: Shapiro, L.]]

OCA at 06:28, 4 May 2011

OCA — Wed, 04 May 2011 06:28:21 GMT

←Older revision		Revision as of 06:28, 4 May 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3qrb is ON HOLD	+	The entry 3qrb is ON HOLD until Paper Publication

	Authors: Jin, X., Shapiro, L.		Authors: Jin, X., Shapiro, L.

	Description: crystal structure of E-cadherin EC1-2 P5A P6A		Description: crystal structure of E-cadherin EC1-2 P5A P6A

OCA at 10:17, 21 April 2011

OCA — Thu, 21 Apr 2011 10:17:51 GMT

←Older revision		Revision as of 10:17, 21 April 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3qrb is ON HOLD ~~until sometime in the future~~	+	The entry 3qrb is ON HOLD

	Authors: Jin, X., Shapiro, L.		Authors: Jin, X., Shapiro, L.

	Description: crystal structure of E-cadherin EC1-2 P5A P6A		Description: crystal structure of E-cadherin EC1-2 P5A P6A