3qsy - Revision history

OCA at 17:14, 1 November 2023

OCA — Wed, 01 Nov 2023 17:14:51 GMT

←Older revision		Revision as of 17:14, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3qsy' size='340' side='right'caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3qsy' size='340' side='right'caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~] and [https://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia coli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID~~-~~GUANYLATE+ESTER'>GNP</scene>~~, ~~<scene name='pdbligand=MET:METHIONINE'>MET</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.2Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~eif2g ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=2287 ATCC 35091]), eif2a ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [https://pdbe.org/3qsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [https://www.ebi.ac.uk/pdbsum/3qsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [https://pdbe.org/3qsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [https://www.ebi.ac.uk/pdbsum/3qsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~IF2G_SULSO IF2G_SULSO]~~] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA ~~(By similarity)~~. [~~[https~~:~~//www.uniprot.org/uniprot/IF2A_SULSO IF2A_SULSO~~]~~] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).~~	+	[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35091]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Garber, M B~~]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: ~~Nikonov, O S~~]]	+	[[Category: Garber MB]]
-	[[Category: Nikonov~~, S V~~]]	+	[[Category: Nikonov OS]]
-	[[Category: ~~Nikulin, A D~~]]	+	[[Category: Nikonov SV]]
-	[[Category: ~~Stolboushkina, E A~~]]	+	[[Category: Nikulin AD]]
-	[[Category: ~~Zelinskaya, N V~~]]	+	[[Category: Stolboushkina EA]]
-	[[Category: ~~Archaea]]~~	+	[[Category: Zelinskaya NV]]
-	~~[[Category: E/aif2]]~~	+
-	~~[[Category: G-protein]]~~	+
-	~~[[Category: Gtp binding]]~~	+
-	~~[[Category: Met-trnai binding]]~~	+
-	~~[[Category: Mrna binding]]~~	+
-	~~[[Category: Ribosome]]~~	+
-	~~[[Category: Ribosome binding]]~~	+
-	~~[[Category: Translation initiation]]~~	+
-	~~[[Category: Translation-rna complex]]~~	+
-	~~[[Category: Trnai~~]]	+

OCA at 06:22, 8 June 2022

OCA — Wed, 08 Jun 2022 06:22:36 GMT

←Older revision		Revision as of 06:22, 8 June 2022
Line 1:		Line 1:

	==Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea==		==Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea==
-	<StructureSection load='3qsy' size='340' side='right' caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>	+	<StructureSection load='3qsy' size='340' side='right'caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091] and [~~http~~://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3QSY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QSY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [~~http~~://pdbe.org/3qsy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3qsy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [https://pdbe.org/3qsy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [https://www.ebi.ac.uk/pdbsum/3qsy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity). [[~~http~~://www.uniprot.org/uniprot/IF2A_SULSO IF2A_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).	+	[[https://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity). [[https://www.uniprot.org/uniprot/IF2A_SULSO IF2A_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:

	==See Also==		==See Also==
-	*[[~~TRNA~~\|~~TRNA~~]]	+	*[[Transfer RNA (tRNA)\|Transfer RNA (tRNA)]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 28:
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
	[[Category: Garber, M B]]		[[Category: Garber, M B]]
	[[Category: Nikonov, O S]]		[[Category: Nikonov, O S]]

OCA at 09:40, 4 August 2016

OCA — Thu, 04 Aug 2016 09:40:31 GMT

←Older revision		Revision as of 09:40, 4 August 2016
Line 1:		Line 1:
		+
	==Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea==		==Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea==
	<StructureSection load='3qsy' size='340' side='right' caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>		<StructureSection load='3qsy' size='340' side='right' caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [http://www.ebi.ac.uk/pdbsum/3qsy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [http://pdbe.org/3qsy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [http://www.ebi.ac.uk/pdbsum/3qsy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qsy ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3qsy" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[TRNA\|TRNA]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:25, 24 December 2014

OCA — Wed, 24 Dec 2014 08:25:45 GMT

←Older revision		Revision as of 08:25, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QSY FirstGlance]. <br>		<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QSY FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [http://www.ebi.ac.uk/pdbsum/3qsy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [http://www.ebi.ac.uk/pdbsum/3qsy PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity). [[http://www.uniprot.org/uniprot/IF2A_SULSO IF2A_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Garber, M B.]]	+	[[Category: Garber, M B]]
-	[[Category: Nikonov, O S.]]	+	[[Category: Nikonov, O S]]
-	[[Category: Nikonov, S V.]]	+	[[Category: Nikonov, S V]]
-	[[Category: Nikulin, A D.]]	+	[[Category: Nikulin, A D]]
-	[[Category: Stolboushkina, E A.]]	+	[[Category: Stolboushkina, E A]]
-	[[Category: Zelinskaya, N V.]]	+	[[Category: Zelinskaya, N V]]
	[[Category: Archaea]]		[[Category: Archaea]]
	[[Category: E/aif2]]		[[Category: E/aif2]]

OCA at 03:23, 4 September 2014

OCA — Thu, 04 Sep 2014 03:23:53 GMT

←Older revision		Revision as of 03:23, 4 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}~~	+	==Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea==
-	===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===	+	<StructureSection load='3qsy' size='340' side='right' caption='[[3qsy]], [[Resolution\|resolution]] 3.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23291527}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091] and [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QSY FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">eif2g ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091]), eif2a ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qsy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qsy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qsy RCSB], [http://www.ebi.ac.uk/pdbsum/3qsy PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Heterotrimeric aIF2alphabetagamma (archaeal homologue of the eukaryotic translation initiation factor 2) in its GTP-bound form delivers Met-tRNA(i)(Met) to the small ribosomal subunit. It is known that the heterodimer containing the GTP-bound gamma subunit and domain 3 of the alpha subunit of aIF2 is required for the formation of a stable complex with Met-tRNA(i). Here, the crystal structure of an incomplete ternary complex including aIF2alphaD3gammaGDPNPMet-tRNA(f)(Met) has been solved at 3.2A resolution. This structure is in good agreement with biochemical and hydroxyl radical probing data. The analysis of the complex shows that despite the structural similarity of aIF2gamma and the bacterial translation elongation factor EF-Tu, their modes of tRNA binding are very different. Remarkably, the recently published 5.0-A-resolution structure of almost the same ternary initiation complex differs dramatically from the structure presented. Reasons for this discrepancy are discussed.

-	~~==Function==~~	+	Crystal Structure of the Archaeal Translation Initiation Factor 2 in Complex with a GTP Analogue and Met-tRNA(f)(Met).,Stolboushkina E, Nikonov S, Zelinskaya N, Arkhipova V, Nikulin A, Garber M, Nikonov O J Mol Biol. 2013 Jan 3. pii: S0022-2836(12)00971-0. doi:, 10.1016/j.jmb.2012.12.023. PMID:23291527<ref>PMID:23291527</ref>
-	~~[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-~~2 ~~functions~~ in ~~the early steps of protein synthesis by forming~~ a ~~ternary complex with~~ GTP and ~~initiator~~ tRNA (~~By similarity~~). ~~[[http://www~~.~~uniprot~~.~~org/uniprot/IF2A_SULSO IF2A_SULSO]] eIF~~-~~2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA~~ (~~By similarity~~).	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3qsy]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli] and [http://en~~.~~wikipedia.org~~/~~wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA].~~	+	</div>
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:023291527</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
		+	[[Category: Atcc 35091]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Sulfolobus solfataricus]]
	[[Category: Garber, M B.]]		[[Category: Garber, M B.]]
	[[Category: Nikonov, O S.]]		[[Category: Nikonov, O S.]]

OCA at 10:22, 19 June 2013

OCA — Wed, 19 Jun 2013 10:22:52 GMT

←Older revision		Revision as of 10:22, 19 June 2013
Line 1:		Line 1:
-	[[Image:3qsy.png\|left\|200px]]
-
	{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}		{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}
-
	===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===		===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===
-
	{{ABSTRACT_PUBMED_23291527}}		{{ABSTRACT_PUBMED_23291527}}
		+
		+	==Function==
		+	[[http://www.uniprot.org/uniprot/IF2G_SULSO IF2G_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity). [[http://www.uniprot.org/uniprot/IF2A_SULSO IF2A_SULSO]] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA (By similarity).

	==About this Structure==		==About this Structure==
	[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA].		[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023291527</ref><references group="xtra"/><references/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]

OCA at 13:01, 6 February 2013

OCA — Wed, 06 Feb 2013 13:01:34 GMT

←Older revision		Revision as of 13:01, 6 February 2013
Line 1:		Line 1:
-	[[Image:3qsy.~~jpg~~\|left\|200px]]	+	[[Image:3qsy.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3qsy", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}		{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}

	===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===		===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===

		+	{{ABSTRACT_PUBMED_23291527}}

	==About this Structure==		==About this Structure==

OCA at 07:42, 21 March 2012

OCA — Wed, 21 Mar 2012 07:42:49 GMT

←Older revision		Revision as of 07:42, 21 March 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3qsy.jpg\|left\|200px]]

-	The ~~entry 3qsy~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3qsy", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3qsy\| PDB=3qsy \| SCENE= }}

-	~~Authors: Nikonov, O.S., Stolboushkina, E.A., Zelinskaya, N.V., Nikulin, A.D., Garber, M.B., Nikonov, S.V.~~	+	===Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea===

-	~~Description~~: ~~Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in~~ Archaea	+
		+	==About this Structure==
		+	[[3qsy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QSY OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Sulfolobus solfataricus]]
		+	[[Category: Garber, M B.]]
		+	[[Category: Nikonov, O S.]]
		+	[[Category: Nikonov, S V.]]
		+	[[Category: Nikulin, A D.]]
		+	[[Category: Stolboushkina, E A.]]
		+	[[Category: Zelinskaya, N V.]]
		+	[[Category: Archaea]]
		+	[[Category: E/aif2]]
		+	[[Category: G-protein]]
		+	[[Category: Gtp binding]]
		+	[[Category: Met-trnai binding]]
		+	[[Category: Mrna binding]]
		+	[[Category: Ribosome]]
		+	[[Category: Ribosome binding]]
		+	[[Category: Translation initiation]]
		+	[[Category: Translation-rna complex]]
		+	[[Category: Trnai]]

OCA at 05:10, 18 May 2011

OCA — Wed, 18 May 2011 05:10:43 GMT

←Older revision		Revision as of 05:10, 18 May 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3qsy is ON HOLD	+	The entry 3qsy is ON HOLD until Paper Publication

	Authors: Nikonov, O.S., Stolboushkina, E.A., Zelinskaya, N.V., Nikulin, A.D., Garber, M.B., Nikonov, S.V.		Authors: Nikonov, O.S., Stolboushkina, E.A., Zelinskaya, N.V., Nikulin, A.D., Garber, M.B., Nikonov, S.V.

	Description: Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea		Description: Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea

OCA at 06:45, 23 March 2011

OCA — Wed, 23 Mar 2011 06:45:43 GMT

←Older revision		Revision as of 06:45, 23 March 2011
Line 3:		Line 3:
	The entry 3qsy is ON HOLD		The entry 3qsy is ON HOLD

-	Authors: Nikonov O.S. , Stolboushkina E.A. , Zelinskaya N.V., Nikulin A.D. , Garber M.B. , Nikonov S.V.	+	Authors: Nikonov, O.S., Stolboushkina, E.A., Zelinskaya, N.V., Nikulin, A.D., Garber, M.B., Nikonov, S.V.

	Description: Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea		Description: Recognition of the methionylated initiator tRNA by the translation initiation factor 2 in Archaea