3qwb - Revision history

OCA at 17:15, 1 November 2023

OCA — Wed, 01 Nov 2023 17:15:17 GMT

←Older revision		Revision as of 17:15, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3qwb' size='340' side='right'caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='3qwb' size='340' side='right'caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Baker's_yeast Baker's yeast~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWB FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.59Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3qwa\|3qwa]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>YBR0421, YBR046C, ZTA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~559292 Baker's yeast])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/~~NADPH~~:quinone_reductase NADPH:quinone reductase], with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [https://pdbe.org/3qwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [https://www.ebi.ac.uk/pdbsum/3qwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [https://pdbe.org/3qwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [https://www.ebi.ac.uk/pdbsum/3qwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwb ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/QOR_YEAST QOR_YEAST]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Baker's yeast]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~NADPH:quinone reductase~~]]	+	[[Category: Saccharomyces cerevisiae S288C]]
-	[[Category: Bao~~, Z Z~~]]	+	[[Category: Bao ZZ]]
-	[[Category: Chen~~, Y X~~]]	+	[[Category: Chen YX]]
-	[[Category: Guo~~, P C~~]]	+	[[Category: Guo PC]]
-	[[Category: Ma~~, X X~~]]	+	[[Category: Ma XX]]
-	[[Category: Zhou~~, C Z]]~~	+	[[Category: Zhou CZ]]
-	~~[[Category: Cytoplasm and nucleus]]~~	+
-	~~[[Category: Nadph]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Quinone oxidoreductase]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 05:39, 15 June 2022

OCA — Wed, 15 Jun 2022 05:39:00 GMT

←Older revision		Revision as of 05:39, 15 June 2022
Line 1:		Line 1:

	==Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH==		==Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH==
-	<StructureSection load='3qwb' size='340' side='right' caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>	+	<StructureSection load='3qwb' size='340' side='right'caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3QWB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qwa\|3qwa]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [~~http~~://pdbe.org/3qwb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3qwb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [https://pdbe.org/3qwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [https://www.ebi.ac.uk/pdbsum/3qwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Baker's yeast]]		[[Category: Baker's yeast]]
		+	[[Category: Large Structures]]
	[[Category: NADPH:quinone reductase]]		[[Category: NADPH:quinone reductase]]
	[[Category: Bao, Z Z]]		[[Category: Bao, Z Z]]

OCA at 12:56, 5 August 2016

OCA — Fri, 05 Aug 2016 12:56:03 GMT

←Older revision		Revision as of 12:56, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH==		==Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH==
	<StructureSection load='3qwb' size='340' side='right' caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='3qwb' size='340' side='right' caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Baker's_yeast Baker's yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~4932 Saccharomyces cerevisiae~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=559292 Baker's yeast])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [http://www.ebi.ac.uk/pdbsum/3qwb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [http://pdbe.org/3qwb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [http://www.ebi.ac.uk/pdbsum/3qwb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwb ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3qwb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Baker's yeast]]
	[[Category: NADPH:quinone reductase]]		[[Category: NADPH:quinone reductase]]
-	[[Category: Saccharomyces cerevisiae]]
	[[Category: Bao, Z Z]]		[[Category: Bao, Z Z]]
	[[Category: Chen, Y X]]		[[Category: Chen, Y X]]

OCA at 21:04, 3 January 2015

OCA — Sat, 03 Jan 2015 21:04:39 GMT

←Older revision		Revision as of 21:04, 3 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWB FirstGlance]. <br>		<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWB FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [http://www.ebi.ac.uk/pdbsum/3qwb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [http://www.ebi.ac.uk/pdbsum/3qwb PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 15:
	Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1.,Guo PC, Ma XX, Bao ZZ, Ma JD, Chen Y, Zhou CZ J Struct Biol. 2011 Oct;176(1):112-8. Epub 2011 Jul 26. PMID:21820057<ref>PMID:21820057</ref>		Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1.,Guo PC, Ma XX, Bao ZZ, Ma JD, Chen Y, Zhou CZ J Struct Biol. 2011 Oct;176(1):112-8. Epub 2011 Jul 26. PMID:21820057<ref>PMID:21820057</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 23:		Line 23:
	[[Category: NADPH:quinone reductase]]		[[Category: NADPH:quinone reductase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Bao, Z Z.]]	+	[[Category: Bao, Z Z]]
-	[[Category: Chen, Y X.]]	+	[[Category: Chen, Y X]]
-	[[Category: Guo, P C.]]	+	[[Category: Guo, P C]]
-	[[Category: Ma, X X.]]	+	[[Category: Ma, X X]]
-	[[Category: Zhou, C Z.]]	+	[[Category: Zhou, C Z]]
	[[Category: Cytoplasm and nucleus]]		[[Category: Cytoplasm and nucleus]]
	[[Category: Nadph]]		[[Category: Nadph]]

OCA at 04:37, 5 June 2014

OCA — Thu, 05 Jun 2014 04:37:53 GMT

←Older revision		Revision as of 04:37, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3qwb.~~jpg~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH==
		+	<StructureSection load='3qwb' size='340' side='right' caption='[[3qwb]], [[Resolution\|resolution]] 1.59Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QWB FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qwa\|3qwa]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">YBR0421, YBR046C, ZTA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH:quinone_reductase NADPH:quinone reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.5.5 1.6.5.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qwb RCSB], [http://www.ebi.ac.uk/pdbsum/3qwb PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Quinone oxidoreductase (QOR EC1.6.5.5) catalyzes the reduction of quinone to hydroxyquinone using NADPH as a cofactor. Here we present the crystal structure of the zeta-crystallin-like QOR Zta1 from Saccharomycescerevisiae in apo-form at 2.00 A and complexed with NADPH at 1.59 A resolution. Zta1 forms a homodimer, with each subunit containing a catalytic and a cofactor-binding domain. Upon NADPH binding to the interdomain cleft, the two domains shift towards each other, producing a better fit for NADPH, and tightening substrate binding. Computational simulation combined with site-directed mutagenesis and enzymatic activity analysis defined a potential quinone-binding site that determines the stringent substrate specificity. Moreover, multiple-sequence alignment and kinetics assays implied that a single-residue change from Arg in lower organisms to Gly in vertebrates possibly resulted in elevation of enzymatic activity of zeta-crystallin-like QORs throughout evolution.

-	<!--	+	Structural insights into the cofactor-assisted substrate recognition of yeast quinone oxidoreductase Zta1.,Guo PC, Ma XX, Bao ZZ, Ma JD, Chen Y, Zhou CZ J Struct Biol. 2011 Oct;176(1):112-8. Epub 2011 Jul 26. PMID:21820057<ref>PMID:21820057</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3qwb"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3qwb\| PDB=3qwb \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21820057}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21820057 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21820057}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3qwb]] is a 4 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021820057<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: NADPH:quinone reductase]]		[[Category: NADPH:quinone reductase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]

OCA at 06:25, 8 February 2012

OCA — Wed, 08 Feb 2012 06:25:57 GMT

←Older revision		Revision as of 06:25, 8 February 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3qwb.jpg\|left\|200px]]

-	The ~~entry 3qwb~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3qwb", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3qwb\| PDB=3qwb \| SCENE= }}

-	~~Authors: Guo, P.C., Ma, X.X., Bao, Z.Z., Chen, Y.X., Zhou, C.Z.~~	+	===Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH===

-	~~Description~~: ~~Crystal~~ structure of Saccharomyces cerevisiae ~~Zeta~~-~~crystallin-like~~ quinone oxidoreductase ~~Zta1 complexed with NADPH~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21820057}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21820057 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21820057}}
		+
		+	==About this Structure==
		+	[[3qwb]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWB OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021820057</ref><references group="xtra"/>
		+	[[Category: NADPH:quinone reductase]]
		+	[[Category: Saccharomyces cerevisiae]]
		+	[[Category: Bao, Z Z.]]
		+	[[Category: Chen, Y X.]]
		+	[[Category: Guo, P C.]]
		+	[[Category: Ma, X X.]]
		+	[[Category: Zhou, C Z.]]
		+	[[Category: Cytoplasm and nucleus]]
		+	[[Category: Nadph]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Quinone oxidoreductase]]
		+	[[Category: Rossmann fold]]

OCA at 07:45, 30 March 2011

OCA — Wed, 30 Mar 2011 07:45:59 GMT

←Older revision		Revision as of 07:45, 30 March 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3qwb is ON HOLD	+	The entry 3qwb is ON HOLD until Paper Publication

	Authors: Guo, P.C., Ma, X.X., Bao, Z.Z., Chen, Y.X., Zhou, C.Z.		Authors: Guo, P.C., Ma, X.X., Bao, Z.Z., Chen, Y.X., Zhou, C.Z.

	Description: Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH		Description: Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH

OCA at 06:46, 23 March 2011

OCA — Wed, 23 Mar 2011 06:46:47 GMT

←Older revision		Revision as of 06:46, 23 March 2011
Line 3:		Line 3:
	The entry 3qwb is ON HOLD		The entry 3qwb is ON HOLD

-	Authors: Guo, P.C, Ma, X.X, Bao, Z.Z, Chen, Y.X, Zhou, C.Z	+	Authors: Guo, P.C., Ma, X.X., Bao, Z.Z., Chen, Y.X., Zhou, C.Z.

-	Description: Crystal ~~structures~~ of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 ~~and complex~~ with NADPH	+	Description: Crystal structure of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 complexed with NADPH

OCA: Protected "3qwb" [edit=sysop:move=sysop]

OCA — Wed, 09 Mar 2011 06:08:52 GMT

Protected "3qwb" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:08, 9 March 2011

OCA: New page: '''Unreleased structure''' The entry 3qwb is ON HOLD Authors: Guo, P.C, Ma, X.X, Bao, Z.Z, Chen, Y.X, Zhou, C.Z Description: Crystal structures of Saccharomyces cerevisiae Zeta-crystal...

OCA — Wed, 09 Mar 2011 06:08:50 GMT

New page: '''Unreleased structure''' The entry 3qwb is ON HOLD Authors: Guo, P.C, Ma, X.X, Bao, Z.Z, Chen, Y.X, Zhou, C.Z Description: Crystal structures of Saccharomyces cerevisiae Zeta-crystal...

New page

'''Unreleased structure'''

The entry 3qwb is ON HOLD

Authors: Guo, P.C, Ma, X.X, Bao, Z.Z, Chen, Y.X, Zhou, C.Z

Description: Crystal structures of Saccharomyces cerevisiae Zeta-crystallin-like quinone oxidoreductase Zta1 and complex with NADPH