3rwl - Revision history

OCA at 09:45, 1 March 2024

OCA — Fri, 01 Mar 2024 09:45:52 GMT

←Older revision		Revision as of 09:45, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3rwl' size='340' side='right'caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3rwl' size='340' side='right'caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_51380 Atcc 51380~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RWL FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>ahpG1, Sphingomonas sp. ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~33050 ATCC 51380])</td~~><~~/tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [https://pdbe.org/3rwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [https://www.ebi.ac.uk/pdbsum/3rwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [https://pdbe.org/3rwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [https://www.ebi.ac.uk/pdbsum/3rwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwl ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q5F4D9_SPHMC Q5F4D9_SPHMC]
-	Directed evolution of a monooxygenase to achieve very high enantioselectivity for hydroxylation at non-activated carbon atoms is demonstrated for the first time, where a triple mutant of P450pyr hydroxylase is obtained via determination of enzyme structure, iterative saturation mutagenesis, and high-throughput screening with a MS-based ee assay to increase the product ee from 53% to 98% for the hydroxylation of N-benzyl pyrrolidine to (S)-N-benzyl 3-hydroxypyrrolidine.	+
-		+
-	~~Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom.,Pham SQ, Pompidor G, Liu J, Li XD, Li Z Chem Commun (Camb). 2012 May 14;48(38)~~:~~4618-20. Epub 2012 Mar 19. PMID:22430002<ref>PMID:22430002<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3rwl" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Alkane 1-monooxygenase]]
-	[[Category: Atcc 51380]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pompidor, G~~]]	+	[[Category: Sphingopyxis macrogoltabida]]
-	[[Category: ~~Oxidoreductase]]~~	+	[[Category: Pompidor G]]
-	~~[[Category: P450 monooxygenase~~]]	+

OCA at 10:28, 22 June 2022

OCA — Wed, 22 Jun 2022 10:28:14 GMT

←Older revision		Revision as of 10:28, 22 June 2022
Line 1:		Line 1:

	==Structure of P450pyr hydroxylase==		==Structure of P450pyr hydroxylase==
-	<StructureSection load='3rwl' size='340' side='right' caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3rwl' size='340' side='right'caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_51380 Atcc 51380]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3RWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_51380 Atcc 51380]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RWL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 ATCC 51380])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 ATCC 51380])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [~~http~~://pdbe.org/3rwl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3rwl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwl ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [https://pdbe.org/3rwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [https://www.ebi.ac.uk/pdbsum/3rwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwl ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 24:
	[[Category: Alkane 1-monooxygenase]]		[[Category: Alkane 1-monooxygenase]]
	[[Category: Atcc 51380]]		[[Category: Atcc 51380]]
		+	[[Category: Large Structures]]
	[[Category: Pompidor, G]]		[[Category: Pompidor, G]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450 monooxygenase]]		[[Category: P450 monooxygenase]]

OCA at 17:16, 11 August 2016

OCA — Thu, 11 Aug 2016 17:16:54 GMT

←Older revision		Revision as of 17:16, 11 August 2016
Line 1:		Line 1:
		+
	==Structure of P450pyr hydroxylase==		==Structure of P450pyr hydroxylase==
	<StructureSection load='3rwl' size='340' side='right' caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3rwl' size='340' side='right' caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_51380 Atcc 51380]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 ~~Sphingopyxis macrogoltabida~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 ATCC 51380])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [http://www.ebi.ac.uk/pdbsum/3rwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [http://pdbe.org/3rwl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [http://www.ebi.ac.uk/pdbsum/3rwl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rwl ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3rwl" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Alkane 1-monooxygenase]]		[[Category: Alkane 1-monooxygenase]]
-	[[Category: ~~Sphingopyxis macrogoltabida~~]]	+	[[Category: Atcc 51380]]
	[[Category: Pompidor, G]]		[[Category: Pompidor, G]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450 monooxygenase]]		[[Category: P450 monooxygenase]]

OCA at 10:47, 4 January 2015

OCA — Sun, 04 Jan 2015 10:47:17 GMT

←Older revision		Revision as of 10:47, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWL FirstGlance]. <br>		<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWL FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 Sphingopyxis macrogoltabida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 Sphingopyxis macrogoltabida])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [http://www.ebi.ac.uk/pdbsum/3rwl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [http://www.ebi.ac.uk/pdbsum/3rwl PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 14:
	Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom.,Pham SQ, Pompidor G, Liu J, Li XD, Li Z Chem Commun (Camb). 2012 May 14;48(38):4618-20. Epub 2012 Mar 19. PMID:22430002<ref>PMID:22430002</ref>		Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom.,Pham SQ, Pompidor G, Liu J, Li XD, Li Z Chem Commun (Camb). 2012 May 14;48(38):4618-20. Epub 2012 Mar 19. PMID:22430002<ref>PMID:22430002</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 22:
	[[Category: Alkane 1-monooxygenase]]		[[Category: Alkane 1-monooxygenase]]
	[[Category: Sphingopyxis macrogoltabida]]		[[Category: Sphingopyxis macrogoltabida]]
-	[[Category: Pompidor, G.]]	+	[[Category: Pompidor, G]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: P450 monooxygenase]]		[[Category: P450 monooxygenase]]

OCA at 04:42, 5 June 2014

OCA — Thu, 05 Jun 2014 04:42:46 GMT

←Older revision		Revision as of 04:42, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3rwl.~~png~~\|~~left~~\|~~200px~~]]	+	==Structure of P450pyr hydroxylase==
		+	<StructureSection load='3rwl' size='340' side='right' caption='[[3rwl]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RWL FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ahpG1, Sphingomonas sp. ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33050 Sphingopyxis macrogoltabida])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alkane_1-monooxygenase Alkane 1-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.15.3 1.14.15.3] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rwl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rwl RCSB], [http://www.ebi.ac.uk/pdbsum/3rwl PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Directed evolution of a monooxygenase to achieve very high enantioselectivity for hydroxylation at non-activated carbon atoms is demonstrated for the first time, where a triple mutant of P450pyr hydroxylase is obtained via determination of enzyme structure, iterative saturation mutagenesis, and high-throughput screening with a MS-based ee assay to increase the product ee from 53% to 98% for the hydroxylation of N-benzyl pyrrolidine to (S)-N-benzyl 3-hydroxypyrrolidine.

-	<!--	+	Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom.,Pham SQ, Pompidor G, Liu J, Li XD, Li Z Chem Commun (Camb). 2012 May 14;48(38):4618-20. Epub 2012 Mar 19. PMID:22430002<ref>PMID:22430002</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3rwl"~~, ~~creates the "Structure Box" on the page.~~	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter~~ (~~which sets the initial scene displayed when the page is loaded~~),	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3rwl\| PDB=3rwl \| SCENE= }}~~	+

-	~~===Structure~~ of ~~P450pyr hydroxylase===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22430002}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22430002 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22430002}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3rwl]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022430002<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Alkane 1-monooxygenase]]		[[Category: Alkane 1-monooxygenase]]
	[[Category: Sphingopyxis macrogoltabida]]		[[Category: Sphingopyxis macrogoltabida]]

OCA at 08:09, 25 April 2012

OCA — Wed, 25 Apr 2012 08:09:55 GMT

←Older revision		Revision as of 08:09, 25 April 2012
Line 1:		Line 1:
-	[[Image:3rwl.~~jpg~~\|left\|200px]]	+	[[Image:3rwl.png\|left\|200px]]

	<!--		<!--

OCA at 07:50, 18 April 2012

OCA — Wed, 18 Apr 2012 07:50:35 GMT

←Older revision		Revision as of 07:50, 18 April 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3rwl.jpg\|left\|200px]]

-	The ~~entry 3rwl~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3rwl", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3rwl\| PDB=3rwl \| SCENE= }}

-	~~Authors: Pompidor, G.~~	+	===Structure of P450pyr hydroxylase===

-	~~Description~~: Structure ~~of P450pyr hydroxylase~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22430002}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22430002 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22430002}}
		+
		+	==About this Structure==
		+	[[3rwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sphingopyxis_macrogoltabida Sphingopyxis macrogoltabida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RWL OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022430002</ref><references group="xtra"/>
		+	[[Category: Alkane 1-monooxygenase]]
		+	[[Category: Sphingopyxis macrogoltabida]]
		+	[[Category: Pompidor, G.]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: P450 monooxygenase]]

OCA at 05:24, 1 June 2011

OCA — Wed, 01 Jun 2011 05:24:23 GMT

←Older revision		Revision as of 05:24, 1 June 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3rwl is ON HOLD	+	The entry 3rwl is ON HOLD until Paper Publication

	Authors: Pompidor, G.		Authors: Pompidor, G.

-	Description: Structure of P450pyr ~~hydrolase~~	+	Description: Structure of P450pyr hydroxylase

OCA: Protected "3rwl" [edit=sysop:move=sysop]

OCA — Wed, 18 May 2011 05:17:26 GMT

Protected "3rwl" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:17, 18 May 2011

OCA: New page: '''Unreleased structure''' The entry 3rwl is ON HOLD Authors: Pompidor, G. Description: Structure of P450pyr hydrolase

OCA — Wed, 18 May 2011 05:17:25 GMT

New page: '''Unreleased structure''' The entry 3rwl is ON HOLD Authors: Pompidor, G. Description: Structure of P450pyr hydrolase

New page

'''Unreleased structure'''

The entry 3rwl is ON HOLD

Authors: Pompidor, G.

Description: Structure of P450pyr hydrolase