3rzs - Revision history

OCA at 10:31, 22 June 2022

OCA — Wed, 22 Jun 2022 10:31:56 GMT

←Older revision		Revision as of 10:31, 22 June 2022
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	==Apis mellifera OBP14 in complex with Ta6Br14==		==Apis mellifera OBP14 in complex with Ta6Br14==
-	<StructureSection load='3rzs' size='340' side='right' caption='[[3rzs]], [[Resolution\|resolution]] 1.88Å' scene=''>	+	<StructureSection load='3rzs' size='340' side='right'caption='[[3rzs]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rzs]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Apime Apime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3RZS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rzs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Apime Apime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RZS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3s0a\|3s0a]], [[3s0b\|3s0b]], [[3s0d\|3s0d]], [[3s0e\|3s0e]], [[3s0f\|3s0f]], [[3s0g\|3s0g]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3s0a\|3s0a]], [[3s0b\|3s0b]], [[3s0d\|3s0d]], [[3s0e\|3s0e]], [[3s0f\|3s0f]], [[3s0g\|3s0g]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP_001035313 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 APIME])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP_001035313 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 APIME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3rzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rzs OCA], [~~http~~://pdbe.org/3rzs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3rzs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3rzs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3rzs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rzs OCA], [https://pdbe.org/3rzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rzs RCSB], [https://www.ebi.ac.uk/pdbsum/3rzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rzs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Odorant binding protein\|Odorant binding protein]]
	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]		*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==
Line 27:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: Apime]]		[[Category: Apime]]
		+	[[Category: Large Structures]]
	[[Category: Cambillau, C]]		[[Category: Cambillau, C]]
	[[Category: Iovinella, I]]		[[Category: Iovinella, I]]

OCA at 17:19, 11 August 2016

OCA — Thu, 11 Aug 2016 17:19:28 GMT

←Older revision		Revision as of 17:19, 11 August 2016
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		+
	==Apis mellifera OBP14 in complex with Ta6Br14==		==Apis mellifera OBP14 in complex with Ta6Br14==
	<StructureSection load='3rzs' size='340' side='right' caption='[[3rzs]], [[Resolution\|resolution]] 1.88Å' scene=''>		<StructureSection load='3rzs' size='340' side='right' caption='[[3rzs]], [[Resolution\|resolution]] 1.88Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Apis_mellifera Apis mellifera~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RZS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apime Apime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RZS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3s0a\|3s0a]], [[3s0b\|3s0b]], [[3s0d\|3s0d]], [[3s0e\|3s0e]], [[3s0f\|3s0f]], [[3s0g\|3s0g]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3s0a\|3s0a]], [[3s0b\|3s0b]], [[3s0d\|3s0d]], [[3s0e\|3s0e]], [[3s0f\|3s0f]], [[3s0g\|3s0g]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP_001035313 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 ~~Apis mellifera~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP_001035313 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 APIME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rzs RCSB], [http://www.ebi.ac.uk/pdbsum/3rzs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rzs OCA], [http://pdbe.org/3rzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3rzs RCSB], [http://www.ebi.ac.uk/pdbsum/3rzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3rzs ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3rzs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Odorant binding protein\|Odorant binding protein]]		*[[Odorant binding protein\|Odorant binding protein]]
		+	*[[Odorant binding protein 3D structures\|Odorant binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Apis mellifera~~]]	+	[[Category: Apime]]
	[[Category: Cambillau, C]]		[[Category: Cambillau, C]]
	[[Category: Iovinella, I]]		[[Category: Iovinella, I]]

OCA at 08:38, 18 December 2014

OCA — Thu, 18 Dec 2014 08:38:20 GMT

←Older revision		Revision as of 08:38, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3rzs~~\| ~~PDB~~=3rzs \| ~~SCENE~~= }}	+	==Apis mellifera OBP14 in complex with Ta6Br14==
-	===Apis mellifera ~~OBP14 in complex with Ta6Br14~~===	+	<StructureSection load='3rzs' size='340' side='right' caption='[[3rzs]], [[Resolution\|resolution]] 1.88Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22075131}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RZS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TBR:HEXATANTALUM+DODECABROMIDE'>TBR</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3s0a\|3s0a]], [[3s0b\|3s0b]], [[3s0d\|3s0d]], [[3s0e\|3s0e]], [[3s0f\|3s0f]], [[3s0g\|3s0g]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">NP_001035313 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 Apis mellifera])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rzs RCSB], [http://www.ebi.ac.uk/pdbsum/3rzs PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Apis mellifera (Amel) relies on its olfactory system to detect and identify new-sources of floral food. The Odorant-Binding Proteins (OBPs) are the first proteins involved in odorant recognition and interaction, before activation of the olfactory receptors. The Amel genome possess a set of 21 OBPs, much fewer compared to the 60-70 OBPs found in Diptera genomes. We have undertaken a structural proteomics study of Amel OBPs, alone or in complex with odorant or model compounds. We report here the first 3D structure of a member of the C-minus class OBPs, AmelOBP14, characterized by only two disulfide bridges of the three typical of classical OBPs. We show that AmelOBP14 possesses a core of 6 alpha-helices comparable to that of classical OBPs, and an extra exposed C-terminal helix. Its binding site is located within this core and is completely closed. Fluorescent experiments using 1-NPN displacement demonstrate that AmelOBP14 is able to bind several compounds with sub micromolar dissociation constants, among which citralva and eugenol exhibit the highest affinities. We have determined the structures of AmelOBP14 in complex with 1-NPN, eugenol and citralva, explaining their strong binding. Finally, by introducing a double cysteine mutant at positions 44 and 97, we show that a third disulfide bridge was formed in the same position as in classical OBPs without disturbing the fold of AmelOBP14.

-	~~==About this Structure==~~	+	Crystal structure of Apis mellifera OBP14, a C-minus odorant-binding protein, and its complexes with odorant molecules.,Spinelli S, Lagarde A, Iovinella I, Legrand P, Tegoni M, Pelosi P, Cambillau C Insect Biochem Mol Biol. 2011 Oct 31. PMID:22075131<ref>PMID:22075131</ref>
-	~~[[3rzs]] is~~ a ~~1 chain structure~~ with ~~sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Apis_mellifera Apis mellifera]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3RZS OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Odorant binding protein\|Odorant binding protein]]		*[[Odorant binding protein\|Odorant binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022075131<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Apis mellifera]]		[[Category: Apis mellifera]]
-	[[Category: Cambillau, C.]]	+	[[Category: Cambillau, C]]
-	[[Category: Iovinella, I.]]	+	[[Category: Iovinella, I]]
-	[[Category: Lagarde, A.]]	+	[[Category: Lagarde, A]]
-	[[Category: Pelosi, P.]]	+	[[Category: Pelosi, P]]
-	[[Category: Spinelli, S.]]	+	[[Category: Spinelli, S]]
-	[[Category: Tegoni, M.]]	+	[[Category: Tegoni, M]]
	[[Category: All helical protein]]		[[Category: All helical protein]]
	[[Category: Antennae]]		[[Category: Antennae]]
	[[Category: Transport protein]]		[[Category: Transport protein]]
	[[Category: Unknown odorant molecule]]		[[Category: Unknown odorant molecule]]

OCA at 11:05, 11 March 2013

OCA — Mon, 11 Mar 2013 11:05:18 GMT

←Older revision		Revision as of 11:05, 11 March 2013
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-	[[Image:3rzs.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_3rzs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3rzs\| PDB=3rzs \| SCENE= }}		{{STRUCTURE_3rzs\| PDB=3rzs \| SCENE= }}
-
	===Apis mellifera OBP14 in complex with Ta6Br14===		===Apis mellifera OBP14 in complex with Ta6Br14===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22075131}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22075131 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22075131}}		{{ABSTRACT_PUBMED_22075131}}

	==About this Structure==		==About this Structure==
	[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA].		[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA].
		+
		+	==See Also==
		+	*[[Odorant binding protein\|Odorant binding protein]]

	==Reference==		==Reference==

OCA at 08:09, 7 December 2011

OCA — Wed, 07 Dec 2011 08:09:30 GMT

←Older revision		Revision as of 08:09, 7 December 2011
Line 1:		Line 1:
-	[[Image:3rzs.~~jpg~~\|left\|200px]]	+	[[Image:3rzs.png\|left\|200px]]

	<!--		<!--

OCA at 06:19, 30 November 2011

OCA — Wed, 30 Nov 2011 06:19:33 GMT

←Older revision		Revision as of 06:19, 30 November 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3rzs.jpg\|left\|200px]]

-	The ~~entry 3rzs~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3rzs", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3rzs\| PDB=3rzs \| SCENE= }}

-	~~Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni, M., Pelosi, P., Cambillau, C.~~	+	===Apis mellifera OBP14 in complex with Ta6Br14===

-	~~Description~~: Apis mellifera ~~OBP14 in complex with Ta6Br14~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22075131}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22075131 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22075131}}
		+
		+	==About this Structure==
		+	[[3rzs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZS OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022075131</ref><references group="xtra"/>
		+	[[Category: Apis mellifera]]
		+	[[Category: Cambillau, C.]]
		+	[[Category: Iovinella, I.]]
		+	[[Category: Lagarde, A.]]
		+	[[Category: Pelosi, P.]]
		+	[[Category: Spinelli, S.]]
		+	[[Category: Tegoni, M.]]
		+	[[Category: All helical protein]]
		+	[[Category: Antennae]]
		+	[[Category: Transport protein]]
		+	[[Category: Unknown odorant molecule]]

OCA at 05:12, 25 May 2011

OCA — Wed, 25 May 2011 05:12:03 GMT

←Older revision		Revision as of 05:12, 25 May 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3rzs is ON HOLD	+	The entry 3rzs is ON HOLD until Paper Publication

-	Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni,M., Pelosi,P., Cambillau, C.	+	Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni, M., Pelosi, P., Cambillau, C.

	Description: Apis mellifera OBP14 in complex with Ta6Br14		Description: Apis mellifera OBP14 in complex with Ta6Br14

OCA: Protected "3rzs" [edit=sysop:move=sysop]

OCA — Wed, 18 May 2011 05:20:40 GMT

Protected "3rzs" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:20, 18 May 2011

OCA: New page: '''Unreleased structure''' The entry 3rzs is ON HOLD Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni,M., Pelosi,P., Cambillau, C. Description: Apis mellifera OBP14 in complex...

OCA — Wed, 18 May 2011 05:20:39 GMT

New page: '''Unreleased structure''' The entry 3rzs is ON HOLD Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni,M., Pelosi,P., Cambillau, C. Description: Apis mellifera OBP14 in complex...

New page

'''Unreleased structure'''

The entry 3rzs is ON HOLD

Authors: Spinelli, S., Lagarde, A., Iovinella, I., Tegoni,M., Pelosi,P., Cambillau, C.

Description: Apis mellifera OBP14 in complex with Ta6Br14