3t0c - Revision history

OCA at 17:28, 1 November 2023

OCA — Wed, 01 Nov 2023 17:28:08 GMT

←Older revision		Revision as of 17:28, 1 November 2023
Line 3:		Line 3:
	<StructureSection load='3t0c' size='340' side='right'caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>		<StructureSection load='3t0c' size='340' side='right'caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_25175 Atcc 25175~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T0C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T0C FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~, ~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.187Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[3l7r\|3l7r]], [[2nq5\|2nq5]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>metE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1309 ATCC 25175])</td~~><~~/tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>[https://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [https://pdbe.org/3t0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [https://www.ebi.ac.uk/pdbsum/3t0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0c ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [https://pdbe.org/3t0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [https://www.ebi.ac.uk/pdbsum/3t0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).	+	[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3t0c" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3t0c" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Methionine synthase 3D structures\|Methionine synthase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
-	[[Category: Atcc 25175]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Fu, T M~~]]	+	[[Category: Streptococcus mutans]]
-	[[Category: ~~Liang, Y H~~]]	+	[[Category: Fu TM]]
-	[[Category: ~~Su, X D~~]]	+	[[Category: Liang YH]]
-	[[Category: ~~Barrel]]~~	+	[[Category: Su XD]]
-	~~[[Category: Mete]]~~	+
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 08:18, 29 June 2022

OCA — Wed, 29 Jun 2022 08:18:17 GMT

←Older revision		Revision as of 08:18, 29 June 2022
Line 1:		Line 1:

	==Crystal structure of Streptococcus mutans MetE complexed with Zinc==		==Crystal structure of Streptococcus mutans MetE complexed with Zinc==
-	<StructureSection load='3t0c' size='340' side='right' caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>	+	<StructureSection load='3t0c' size='340' side='right'caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3T0C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T0C FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3l7r\|3l7r]], [[2nq5\|2nq5]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [~~http~~://pdbe.org/3t0c PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3t0c PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0c ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [https://pdbe.org/3t0c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [https://www.ebi.ac.uk/pdbsum/3t0c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).	+	[[https://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 27:
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Atcc 25175]]		[[Category: Atcc 25175]]
		+	[[Category: Large Structures]]
	[[Category: Fu, T M]]		[[Category: Fu, T M]]
	[[Category: Liang, Y H]]		[[Category: Liang, Y H]]

OCA at 10:19, 4 August 2016

OCA — Thu, 04 Aug 2016 10:19:40 GMT

←Older revision		Revision as of 10:19, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Streptococcus mutans MetE complexed with Zinc==		==Crystal structure of Streptococcus mutans MetE complexed with Zinc==
	<StructureSection load='3t0c' size='340' side='right' caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>		<StructureSection load='3t0c' size='340' side='right' caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Streptococcus_mutans Streptococcus mutans~~]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0C FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_25175 Atcc 25175]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0C FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ~~Streptococcus mutans~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 ATCC 25175])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [http://www.ebi.ac.uk/pdbsum/3t0c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [http://pdbe.org/3t0c PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [http://www.ebi.ac.uk/pdbsum/3t0c PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t0c ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3t0c" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
-	[[Category: ~~Streptococcus mutans~~]]	+	[[Category: Atcc 25175]]
	[[Category: Fu, T M]]		[[Category: Fu, T M]]
	[[Category: Liang, Y H]]		[[Category: Liang, Y H]]

OCA at 08:17, 25 December 2014

OCA — Thu, 25 Dec 2014 08:17:12 GMT

←Older revision		Revision as of 08:17, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0C FirstGlance]. <br>		<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0C FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [http://www.ebi.ac.uk/pdbsum/3t0c PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [http://www.ebi.ac.uk/pdbsum/3t0c PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/METE_STRMU METE_STRMU]] Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 15:		Line 17:
	Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>		Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 23:		Line 25:
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]
-	[[Category: Fu, T M.]]	+	[[Category: Fu, T M]]
-	[[Category: Liang, Y H.]]	+	[[Category: Liang, Y H]]
-	[[Category: Su, X D.]]	+	[[Category: Su, X D]]
	[[Category: Barrel]]		[[Category: Barrel]]
	[[Category: Mete]]		[[Category: Mete]]
	[[Category: Methyltransferase]]		[[Category: Methyltransferase]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 06:19, 5 June 2014

OCA — Thu, 05 Jun 2014 06:19:44 GMT

←Older revision		Revision as of 06:19, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3t0c.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of Streptococcus mutans MetE complexed with Zinc==
		+	<StructureSection load='3t0c' size='340' side='right' caption='[[3t0c]], [[Resolution\|resolution]] 2.19Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T0C FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l7r\|3l7r]], [[2nq5\|2nq5]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">metE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1309 Streptococcus mutans])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/5-methyltetrahydropteroyltriglutamate--homocysteine_S-methyltransferase 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.14 2.1.1.14] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t0c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t0c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t0c RCSB], [http://www.ebi.ac.uk/pdbsum/3t0c PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cobalamin-independent methionine synthase (MetE) catalyzes the direct transfer of a methyl group from methyltetrahydrofolate to l-homocysteine to form methionine. Previous studies have shown that the MetE active site coordinates a zinc atom, which is thought to act as a Lewis acid and plays a role in the activation of thiol. Extended X-ray absorption fine structure studies and mutagenesis experiments identified the zinc-binding site in MetE from Escherichia coli. Further structural investigations of MetE from Thermotoga maritima lead to the proposition of two models: "induced fit" and "dynamic equilibrium", to account for the catalytic mechanisms of MetE. Here, we present crystal structures of oxidized and zinc-replete MetE from Streptococcus mutans at the physiological pH. The structures reveal that zinc is mobile in the active center and has the possibility to invert even in the absence of homocysteine. These structures provide evidence for the dynamic equilibrium model.

-	<!--	+	Crystal Structures of Cobalamin-Independent Methionine Synthase (MetE) from Streptococcus mutans: A Dynamic Zinc-Inversion Model.,Fu TM, Almqvist J, Liang YH, Li L, Huang Y, Su XD J Mol Biol. 2011 Sep 30;412(4):688-97. Epub 2011 Aug 5. PMID:21840320<ref>PMID:21840320</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3t0c"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3t0c\| PDB=3t0c \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~Streptococcus mutans MetE complexed with Zinc===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_21840320}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21840320 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21840320}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3t0c]] is a 1 chain structure with sequence from [http:~~//en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA].	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021840320<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]

OCA at 04:47, 28 September 2011

OCA — Wed, 28 Sep 2011 04:47:27 GMT

←Older revision		Revision as of 04:47, 28 September 2011
Line 1:		Line 1:
-	[[Image:3t0c.~~jpg~~\|left\|200px]]	+	[[Image:3t0c.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===Crystal structure of Streptococcus mutans MetE complexed with Zinc===		===Crystal structure of Streptococcus mutans MetE complexed with Zinc===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21840320}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21840320 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21840320}}

	==About this Structure==		==About this Structure==
	[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA].		[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021840320</ref><references group="xtra"/>
	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]		[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
	[[Category: Streptococcus mutans]]		[[Category: Streptococcus mutans]]

OCA at 08:42, 3 August 2011

OCA — Wed, 03 Aug 2011 08:42:20 GMT

←Older revision		Revision as of 08:42, 3 August 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3t0c.jpg\|left\|200px]]

-	The ~~entry 3t0c~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3t0c", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3t0c\| PDB=3t0c \| SCENE= }}

-	~~Authors: Fu, T.M., Liang, Y.H., Su, X.D.~~	+	===Crystal structure of Streptococcus mutans MetE complexed with Zinc===

-	~~Description~~: ~~Crystal~~ structure of Streptococcus mutans ~~MetE complexed with Zinc~~	+
		+	==About this Structure==
		+	[[3t0c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptococcus_mutans Streptococcus mutans]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3l7s 3l7s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T0C OCA].
		+	[[Category: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase]]
		+	[[Category: Streptococcus mutans]]
		+	[[Category: Fu, T M.]]
		+	[[Category: Liang, Y H.]]
		+	[[Category: Su, X D.]]
		+	[[Category: Barrel]]
		+	[[Category: Mete]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Transferase]]

OCA: Protected "3t0c" [edit=sysop:move=sysop]

OCA — Wed, 27 Jul 2011 05:46:51 GMT

Protected "3t0c" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:46, 27 July 2011

OCA: New page: '''Unreleased structure''' The entry 3t0c is ON HOLD Authors: Fu, T.M., Liang, Y.H., Su, X.D. Description: Crystal structure of Streptococcus mutans MetE complexed with Zinc

OCA — Wed, 27 Jul 2011 05:46:51 GMT

New page: '''Unreleased structure''' The entry 3t0c is ON HOLD Authors: Fu, T.M., Liang, Y.H., Su, X.D. Description: Crystal structure of Streptococcus mutans MetE complexed with Zinc

New page

'''Unreleased structure'''

The entry 3t0c is ON HOLD

Authors: Fu, T.M., Liang, Y.H., Su, X.D.

Description: Crystal structure of Streptococcus mutans MetE complexed with Zinc