3t2t - Revision history

OCA at 16:40, 6 July 2022

OCA — Wed, 06 Jul 2022 16:40:42 GMT

←Older revision		Revision as of 16:40, 6 July 2022
Line 1:		Line 1:

	==Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside==		==Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside==
-	<StructureSection load='3t2t' size='340' side='right' caption='[[3t2t]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3t2t' size='340' side='right'caption='[[3t2t]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t2t]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3T2T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t2t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T2T FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQT:METHYL+2-O-ACETYL-3-O-(4-METHYLBENZOYL)-BETA-D-TALOPYRANOSIDE'>MQT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MQT:METHYL+2-O-ACETYL-3-O-(4-METHYLBENZOYL)-BETA-D-TALOPYRANOSIDE'>MQT</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3til\|3til]], [[3tim\|3tim]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3til\|3til]], [[3tim\|3tim]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [~~http~~://pdbe.org/3t2t PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3t2t PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3t2t ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [https://pdbe.org/3t2t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [https://www.ebi.ac.uk/pdbsum/3t2t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t2t ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>	+	[[https://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[Galectin\|Galectin]]	+	*[[Galectin 3D structures\|Galectin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Blanchard, H]]		[[Category: Blanchard, H]]
	[[Category: Collins, P M]]		[[Category: Collins, P M]]

OCA at 16:34, 5 August 2016

OCA — Fri, 05 Aug 2016 16:34:30 GMT

←Older revision		Revision as of 16:34, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside==		==Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside==
	<StructureSection load='3t2t' size='340' side='right' caption='[[3t2t]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3t2t' size='340' side='right' caption='[[3t2t]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T2T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T2T FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQT:METHYL+2-O-ACETYL-3-O-(4-METHYLBENZOYL)-BETA-D-TALOPYRANOSIDE'>MQT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQT:METHYL+2-O-ACETYL-3-O-(4-METHYLBENZOYL)-BETA-D-TALOPYRANOSIDE'>MQT</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3til\|3til]], [[3tim\|3tim]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3til\|3til]], [[3tim\|3tim]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 ~~Homo sapiens~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [http://www.ebi.ac.uk/pdbsum/3t2t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [http://pdbe.org/3t2t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [http://www.ebi.ac.uk/pdbsum/3t2t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t2t ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3t2t" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 26:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Blanchard, H]]		[[Category: Blanchard, H]]
	[[Category: Collins, P M]]		[[Category: Collins, P M]]

OCA at 20:18, 25 December 2014

OCA — Thu, 25 Dec 2014 20:18:58 GMT

←Older revision		Revision as of 20:18, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [http://www.ebi.ac.uk/pdbsum/3t2t PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [http://www.ebi.ac.uk/pdbsum/3t2t PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 07:21, 21 December 2014

OCA — Sun, 21 Dec 2014 07:21:26 GMT

←Older revision		Revision as of 07:21, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}~~	+	==Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside==
-	===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===	+	<StructureSection load='3t2t' size='340' side='right' caption='[[3t2t]], [[Resolution\|resolution]] 1.90Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22136701}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T2T FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MQT:METHYL+2-O-ACETYL-3-O-(4-METHYLBENZOYL)-BETA-D-TALOPYRANOSIDE'>MQT</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3til\|3til]], [[3tim\|3tim]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">LGALS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t2t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t2t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t2t RCSB], [http://www.ebi.ac.uk/pdbsum/3t2t PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Galectin-1 and galectin-3 have roles in cancer and inflammation. Galectin-1 has recently emerged as a significant protein produced by tumour cells to promote tumour development, angiogenesis and metastasis and consequently represents an important target to inhibit. The design of inhibitors targeting the carbohydrate recognition domain that is known to recognise galactose is an important approach in the fight against cancer. Based on analysis of crystal structures, we pursued the concept that if the galactose were to be replaced with talose (the C2 epimer of galactose) as a scaffold, then O2 substituents would be directed closer to the protein surface and provide opportunity to design inhibitors that are more specific toward particular galectins. Our elucidation of X-ray crystal structures of two of our synthesised talosides in complex with galectin-1 and galectin-3 provide the first atomic information on the interactions of galectins, and indeed any protein, with talosides. These results have enabled a structure-based rationale for the specificity differences shown by galectin-1 and galectin-3 toward these talosides and demonstrate new opportunities for further exploitation as specific inhibitors of galectins.

-	~~==Function==~~	+	Taloside inhibitors of Galectin-1 and Galectin-3.,Collins PM, Oberg CT, Leffler H, Nilsson UJ, Blanchard H Chem Biol Drug Des. 2011 Dec 3. doi: 10.1111/j.1747-0285.2011.01283.x. PMID:22136701<ref>PMID:22136701</ref>
-	~~[[http~~:~~//www.uniprot~~.~~org~~/~~uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation~~. ~~Binds beta~~-~~galactoside and a wide array of complex carbohydrates~~. ~~Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase~~.~~<ref>~~PMID:~~14617626</ref>~~ <ref>PMID:~~18796645~~</ref>	+

-	~~==About this Structure==~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[3t2t]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA].~~	+	</div>

	==See Also==		==See Also==
	*[[Galectin\|Galectin]]		*[[Galectin\|Galectin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:022136701</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Blanchard, H.]]	+	[[Category: Blanchard, H]]
-	[[Category: Collins, P M.]]	+	[[Category: Collins, P M]]
	[[Category: Beta sandwich]]		[[Category: Beta sandwich]]
	[[Category: Lectin]]		[[Category: Lectin]]
	[[Category: Sugar binding protein-inhibitor complex]]		[[Category: Sugar binding protein-inhibitor complex]]

OCA at 11:39, 3 July 2013

OCA — Wed, 03 Jul 2013 11:39:24 GMT

←Older revision		Revision as of 11:39, 3 July 2013
Line 1:		Line 1:
-	[[Image:3t2t.png\|left\|200px]]
-
	{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}		{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}
-
	===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===		===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===
		+	{{ABSTRACT_PUBMED_22136701}}

-	~~{{ABSTRACT_PUBMED_22136701}}~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/LEG1_HUMAN LEG1_HUMAN]] May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase.<ref>PMID:14617626</ref> <ref>PMID:18796645</ref>

	==About this Structure==		==About this Structure==
Line 14:		Line 13:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:022136701</ref><references group="xtra"/>	+	<ref group="xtra">PMID:022136701</ref><references group="xtra"/><references/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Blanchard, H.]]		[[Category: Blanchard, H.]]

OCA at 21:02, 20 October 2012

OCA — Sat, 20 Oct 2012 21:02:12 GMT

←Older revision		Revision as of 21:02, 20 October 2012
Line 1:		Line 1:
-	[[Image:3t2t.~~jpg~~\|left\|200px]]	+	[[Image:3t2t.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3t2t", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}		{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}

	===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===		===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22136701}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22136701 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22136701}}		{{ABSTRACT_PUBMED_22136701}}

	==About this Structure==		==About this Structure==
	[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA].		[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA].
		+
		+	==See Also==
		+	*[[Galectin\|Galectin]]

	==Reference==		==Reference==

OCA at 07:32, 28 December 2011

OCA — Wed, 28 Dec 2011 07:32:31 GMT

←Older revision		Revision as of 07:32, 28 December 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3t2t.jpg\|left\|200px]]

-	The ~~entry 3t2t~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3t2t", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3t2t\| PDB=3t2t \| SCENE= }}

-	~~Authors: Blanchard, H., Collins, P.M.~~	+	===Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside===

-	~~Description: Crystal structure of human galectin~~-~~1 in complex with methyl 2~~-O-~~acetyl~~-3-O-~~toluoyl-beta-D-talopyranoside~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22136701}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22136701 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22136701}}
		+
		+	==About this Structure==
		+	[[3t2t]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T2T OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022136701</ref><references group="xtra"/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Blanchard, H.]]
		+	[[Category: Collins, P M.]]
		+	[[Category: Beta sandwich]]
		+	[[Category: Lectin]]
		+	[[Category: Sugar binding protein-inhibitor complex]]

OCA at 11:05, 14 December 2011

OCA — Wed, 14 Dec 2011 11:05:17 GMT

←Older revision		Revision as of 11:05, 14 December 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3t2t is ON HOLD	+	The entry 3t2t is ON HOLD until Paper Publication

	Authors: Blanchard, H., Collins, P.M.		Authors: Blanchard, H., Collins, P.M.

	Description: Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside		Description: Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside

OCA at 05:44, 7 September 2011

OCA — Wed, 07 Sep 2011 05:44:40 GMT

←Older revision		Revision as of 05:44, 7 September 2011
Line 3:		Line 3:
	The entry 3t2t is ON HOLD		The entry 3t2t is ON HOLD

-	Authors: Blanchard. H, Collins, P.M	+	Authors: Blanchard, H., Collins, P.M.

-	Description: Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl--D-talopyranoside	+	Description: Crystal structure of human galectin-1 in complex with methyl 2-O-acetyl-3-O-toluoyl-beta-D-talopyranoside

OCA: Protected "3t2t" [edit=sysop:move=sysop]

OCA — Wed, 03 Aug 2011 08:24:38 GMT

Protected "3t2t" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:24, 3 August 2011