3t4l - Revision history

OCA at 13:17, 14 March 2024

OCA — Thu, 14 Mar 2024 13:17:26 GMT

←Older revision		Revision as of 13:17, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3t4l' size='340' side='right'caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>		<StructureSection load='3t4l' size='340' side='right'caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4L FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>~~, ~~<scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-~~1~~-OL'>ZEA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.53Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [https://pdbe.org/3t4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [https://www.ebi.ac.uk/pdbsum/3t4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4l ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [https://pdbe.org/3t4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [https://www.ebi.ac.uk/pdbsum/3t4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/AHK4_ARATH AHK4_ARATH]] Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.<ref>PMID:11114883</ref> <ref>PMID:11234017</ref> <ref>PMID:11230563</ref> <ref>PMID:11479382</ref> <ref>PMID:11577198</ref> <ref>PMID:12354925</ref> <ref>PMID:12410813</ref> <ref>PMID:15155880</ref> <ref>PMID:15509853</ref> <ref>PMID:15053761</ref> <ref>PMID:15144379</ref> <ref>PMID:15166290</ref> <ref>PMID:16246292</ref> <ref>PMID:15923327</ref> <ref>PMID:15728338</ref> <ref>PMID:16753566</ref> <ref>PMID:17075078</ref> <ref>PMID:16361392</ref> <ref>PMID:16357038</ref> <ref>PMID:17216481</ref> <ref>PMID:17956858</ref> <ref>PMID:18077346</ref> <ref>PMID:17965178</ref> <ref>PMID:18571199</ref> <ref>PMID:18785832</ref> <ref>PMID:18397377</ref> <ref>PMID:19032596</ref> <ref>PMID:20110319</ref>	+	[https://www.uniprot.org/uniprot/AHK4_ARATH AHK4_ARATH] Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.<ref>PMID:11114883</ref> <ref>PMID:11234017</ref> <ref>PMID:11230563</ref> <ref>PMID:11479382</ref> <ref>PMID:11577198</ref> <ref>PMID:12354925</ref> <ref>PMID:12410813</ref> <ref>PMID:15155880</ref> <ref>PMID:15509853</ref> <ref>PMID:15053761</ref> <ref>PMID:15144379</ref> <ref>PMID:15166290</ref> <ref>PMID:16246292</ref> <ref>PMID:15923327</ref> <ref>PMID:15728338</ref> <ref>PMID:16753566</ref> <ref>PMID:17075078</ref> <ref>PMID:16361392</ref> <ref>PMID:16357038</ref> <ref>PMID:17216481</ref> <ref>PMID:17956858</ref> <ref>PMID:18077346</ref> <ref>PMID:17965178</ref> <ref>PMID:18571199</ref> <ref>PMID:18785832</ref> <ref>PMID:18397377</ref> <ref>PMID:19032596</ref> <ref>PMID:20110319</ref>
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Cytokinins are classic hormones that orchestrate plant growth and development and the integrity of stem cell populations. Cytokinin receptors are eukaryotic sensor histidine kinases that are activated by both naturally occurring adenine-type cytokinins and urea-based synthetic compounds. Crystal structures of the Arabidopsis thaliana histidine kinase 4 sensor domain in complex with different cytokinin ligands now rationalize the hormone-binding specificity of the receptor and may spur the design of new cytokinin ligands.	+
-		+
-	Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.,Hothorn M, Dabi T, Chory J Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459<ref>PMID:21964459</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3t4l" style="background-color:#fffaf0;"></div~~>	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hothorn, M]]	+	[[Category: Hothorn M]]
-	~~[[Category: Endoplasmic reticulum]]~~	+
-	~~[[Category: Hormone receptor]]~~	+
-	~~[[Category: Pas domain]]~~	+
-	~~[[Category: Sensor histidine kinase~~]]	+

OCA at 16:42, 6 July 2022

OCA — Wed, 06 Jul 2022 16:42:43 GMT

←Older revision		Revision as of 16:42, 6 July 2022
Line 1:		Line 1:

	==Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin==		==Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin==
-	<StructureSection load='3t4l' size='340' side='right' caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>	+	<StructureSection load='3t4l' size='340' side='right'caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3T4L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4L FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [~~http~~://pdbe.org/3t4l PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3t4l PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4l ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [https://pdbe.org/3t4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [https://www.ebi.ac.uk/pdbsum/3t4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/AHK4_ARATH AHK4_ARATH]] Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.<ref>PMID:11114883</ref> <ref>PMID:11234017</ref> <ref>PMID:11230563</ref> <ref>PMID:11479382</ref> <ref>PMID:11577198</ref> <ref>PMID:12354925</ref> <ref>PMID:12410813</ref> <ref>PMID:15155880</ref> <ref>PMID:15509853</ref> <ref>PMID:15053761</ref> <ref>PMID:15144379</ref> <ref>PMID:15166290</ref> <ref>PMID:16246292</ref> <ref>PMID:15923327</ref> <ref>PMID:15728338</ref> <ref>PMID:16753566</ref> <ref>PMID:17075078</ref> <ref>PMID:16361392</ref> <ref>PMID:16357038</ref> <ref>PMID:17216481</ref> <ref>PMID:17956858</ref> <ref>PMID:18077346</ref> <ref>PMID:17965178</ref> <ref>PMID:18571199</ref> <ref>PMID:18785832</ref> <ref>PMID:18397377</ref> <ref>PMID:19032596</ref> <ref>PMID:20110319</ref>	+	[[https://www.uniprot.org/uniprot/AHK4_ARATH AHK4_ARATH]] Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.<ref>PMID:11114883</ref> <ref>PMID:11234017</ref> <ref>PMID:11230563</ref> <ref>PMID:11479382</ref> <ref>PMID:11577198</ref> <ref>PMID:12354925</ref> <ref>PMID:12410813</ref> <ref>PMID:15155880</ref> <ref>PMID:15509853</ref> <ref>PMID:15053761</ref> <ref>PMID:15144379</ref> <ref>PMID:15166290</ref> <ref>PMID:16246292</ref> <ref>PMID:15923327</ref> <ref>PMID:15728338</ref> <ref>PMID:16753566</ref> <ref>PMID:17075078</ref> <ref>PMID:16361392</ref> <ref>PMID:16357038</ref> <ref>PMID:17216481</ref> <ref>PMID:17956858</ref> <ref>PMID:18077346</ref> <ref>PMID:17965178</ref> <ref>PMID:18571199</ref> <ref>PMID:18785832</ref> <ref>PMID:18397377</ref> <ref>PMID:19032596</ref> <ref>PMID:20110319</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Hothorn, M]]		[[Category: Hothorn, M]]
	[[Category: Endoplasmic reticulum]]		[[Category: Endoplasmic reticulum]]

OCA at 19:28, 4 August 2016

OCA — Thu, 04 Aug 2016 19:28:35 GMT

←Older revision		Revision as of 19:28, 4 August 2016
Line 1:		Line 1:
		+
	==Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin==		==Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin==
	<StructureSection load='3t4l' size='340' side='right' caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>		<StructureSection load='3t4l' size='340' side='right' caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4L FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4L FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ~~Arabidopsis thaliana~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [http://www.ebi.ac.uk/pdbsum/3t4l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [http://pdbe.org/3t4l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [http://www.ebi.ac.uk/pdbsum/3t4l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4l ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3t4l" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Hothorn, M]]		[[Category: Hothorn, M]]
	[[Category: Endoplasmic reticulum]]		[[Category: Endoplasmic reticulum]]

OCA at 18:46, 24 December 2014

OCA — Wed, 24 Dec 2014 18:46:12 GMT

←Older revision		Revision as of 18:46, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4L FirstGlance]. <br>		<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4L FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [http://www.ebi.ac.uk/pdbsum/3t4l PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [http://www.ebi.ac.uk/pdbsum/3t4l PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AHK4_ARATH AHK4_ARATH]] Cytokinins (CK) receptor related to bacterial two-component regulators. Functions as a histidine kinase and transmits the stress signal to a downstream MAPK cascade. This protein undergoes an ATP-dependent autophosphorylation at a conserved histidine residue in the kinase core, and a phosphoryl group is then transferred to a conserved aspartate residue in the receiver domain. In the presence of cytokinin, feed phosphate to phosphorelay-integrating histidine phosphotransfer protein (HPt) and activates subsequent cascade. In the absence of cytokinin, removes phosphate from HPt proteins, decreasing the system phosphoload. Involved in meristems establishment in seedlings. Acts as a redundant negative regulator of drought and salt stress responses, and abscisic acid (ABA) signaling in a cytokinin-dependent manner. Required to set vascular asymmetric cell divisions that establish phloem and procambium cell lines. Redundant positive regulator of cytokinin signaling that regulates many development process including seed germination, cell division, seed size, chlorophyll retention during leaf senescence, root repression and shoot promotion. Can interact with isoprenoid-type cytokinins trans-zeatin (tZ and tZR), isopentenyladenine (iP), and isopentenyladenosine (iPR), the meta hydroxylated derivative of benzyladenine m-topolin, buta-2,3-dienyladenine (HA-8), penta-2,3-dienyladenine (HA-1), 4-methyl-penta-2,3-dienyladenine (HA-10), 4-hydroxy-2-butynyladenine (RM1), 2-butynyladenine (RM6), and to a lower extent, with cis-zeatin (cZ), zeatin riboside and dihydrozeatin (DZ). Together with AHK3, involved in the cytokinin-dependent responses to Pi starvation and sucrose stresses. Required for the formation of auxin-transporting vascular tissues in the hypocotyl, and primary and lateral roots, but not in adventitious roots, thus leading to auxin basipetal transport that regulates root development and branching. Involved in alkamides (e.g. N-isobutyl decanamide) and N-acylethanolamides (NAE) signaling that control meristematic activity and differentiation processes during plant development. Prevents the uptake of sulfate by mediating cytokinin-dependent down-regulation of high-affinity sulfate transporters (e.g. SULTR1;1 and SULTR1;2) expression in roots. Together with AHK2, required for growth and reproduction promotion stimulated by the endophytic fungus Piriformospora indica in a trans-zeatin-dependent manner. Required to trigger the phytotoxic effect of the snapdragon (Antirrhinum majus) flowers volatile organic compound (VOC) methyl benzoate (MB). Plays a role in the cytokinin-mediated repression of the iron uptake pathway.<ref>PMID:11114883</ref> <ref>PMID:11234017</ref> <ref>PMID:11230563</ref> <ref>PMID:11479382</ref> <ref>PMID:11577198</ref> <ref>PMID:12354925</ref> <ref>PMID:12410813</ref> <ref>PMID:15155880</ref> <ref>PMID:15509853</ref> <ref>PMID:15053761</ref> <ref>PMID:15144379</ref> <ref>PMID:15166290</ref> <ref>PMID:16246292</ref> <ref>PMID:15923327</ref> <ref>PMID:15728338</ref> <ref>PMID:16753566</ref> <ref>PMID:17075078</ref> <ref>PMID:16361392</ref> <ref>PMID:16357038</ref> <ref>PMID:17216481</ref> <ref>PMID:17956858</ref> <ref>PMID:18077346</ref> <ref>PMID:17965178</ref> <ref>PMID:18571199</ref> <ref>PMID:18785832</ref> <ref>PMID:18397377</ref> <ref>PMID:19032596</ref> <ref>PMID:20110319</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.,Hothorn M, Dabi T, Chory J Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459<ref>PMID:21964459</ref>		Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.,Hothorn M, Dabi T, Chory J Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459<ref>PMID:21964459</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
-	[[Category: Hothorn, M.]]	+	[[Category: Hothorn, M]]
	[[Category: Endoplasmic reticulum]]		[[Category: Endoplasmic reticulum]]
	[[Category: Hormone receptor]]		[[Category: Hormone receptor]]
	[[Category: Pas domain]]		[[Category: Pas domain]]
	[[Category: Sensor histidine kinase]]		[[Category: Sensor histidine kinase]]

OCA at 06:12, 5 June 2014

OCA — Thu, 05 Jun 2014 06:12:04 GMT

←Older revision		Revision as of 06:12, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3t4l.~~png~~\|~~left~~\|~~200px~~]]	+	==Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin==
		+	<StructureSection load='3t4l' size='340' side='right' caption='[[3t4l]], [[Resolution\|resolution]] 1.53Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T4L FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=ZEA:(2E)-2-METHYL-4-(9H-PURIN-6-YLAMINO)BUT-2-EN-1-OL'>ZEA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3t4j\|3t4j]], [[3t4k\|3t4k]], [[3t4o\|3t4o]], [[3t4q\|3t4q]], [[3t4s\|3t4s]], [[3t4t\|3t4t]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AHK4, At2g01830, CRE1, RAW1, T23K3.2, WOL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t4l RCSB], [http://www.ebi.ac.uk/pdbsum/3t4l PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Cytokinins are classic hormones that orchestrate plant growth and development and the integrity of stem cell populations. Cytokinin receptors are eukaryotic sensor histidine kinases that are activated by both naturally occurring adenine-type cytokinins and urea-based synthetic compounds. Crystal structures of the Arabidopsis thaliana histidine kinase 4 sensor domain in complex with different cytokinin ligands now rationalize the hormone-binding specificity of the receptor and may spur the design of new cytokinin ligands.

-	~~<!--~~	+	Structural basis for cytokinin recognition by Arabidopsis thaliana histidine kinase 4.,Hothorn M, Dabi T, Chory J Nat Chem Biol. 2011 Oct 2;7(11):766-8. doi: 10.1038/nchembio.667. PMID:21964459<ref>PMID:21964459</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3t4l"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display.~~	+
-	-->	+
-	~~{{STRUCTURE_3t4l\| PDB=3t4l \| SCENE= }}~~	+

-	~~===Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph~~, ~~{{ABSTRACT_PUBMED_21964459}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 21964459 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_21964459}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3t4l]] is a 2 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:021964459<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Hothorn, M.]]		[[Category: Hothorn, M.]]

OCA at 10:52, 14 December 2011

OCA — Wed, 14 Dec 2011 10:52:21 GMT

←Older revision		Revision as of 10:52, 14 December 2011
Line 1:		Line 1:
-	[[Image:3t4l.~~jpg~~\|left\|200px]]	+	[[Image:3t4l.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin===		===Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21964459}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21964459 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21964459}}

	==About this Structure==		==About this Structure==
	[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA].		[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021964459</ref><references group="xtra"/>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Hothorn, M.]]		[[Category: Hothorn, M.]]

OCA at 06:47, 5 October 2011

OCA — Wed, 05 Oct 2011 06:47:46 GMT

←Older revision		Revision as of 06:47, 5 October 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3t4l.jpg\|left\|200px]]

-	The ~~entry 3t4l~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3t4l", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3t4l\| PDB=3t4l \| SCENE= }}

-	~~Authors: Hothorn, M.~~	+	===Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin===

-	~~Description~~: Arabidopsis histidine kinase ~~4 sensor domain in complex with trans-zeatin~~	+
		+	==About this Structure==
		+	[[3t4l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4L OCA].
		+	[[Category: Arabidopsis thaliana]]
		+	[[Category: Hothorn, M.]]
		+	[[Category: Endoplasmic reticulum]]
		+	[[Category: Hormone receptor]]
		+	[[Category: Pas domain]]
		+	[[Category: Sensor histidine kinase]]

OCA at 05:53, 17 August 2011

OCA — Wed, 17 Aug 2011 05:53:38 GMT

←Older revision		Revision as of 05:53, 17 August 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3t4l is ON HOLD	+	The entry 3t4l is ON HOLD until Paper Publication

	Authors: Hothorn, M.		Authors: Hothorn, M.

	Description: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin		Description: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin

OCA: Protected "3t4l" [edit=sysop:move=sysop]

OCA — Wed, 03 Aug 2011 08:26:49 GMT

Protected "3t4l" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:26, 3 August 2011

OCA: New page: '''Unreleased structure''' The entry 3t4l is ON HOLD Authors: Hothorn, M. Description: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin

OCA — Wed, 03 Aug 2011 08:26:49 GMT

New page: '''Unreleased structure''' The entry 3t4l is ON HOLD Authors: Hothorn, M. Description: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin

New page

'''Unreleased structure'''

The entry 3t4l is ON HOLD

Authors: Hothorn, M.

Description: Arabidopsis histidine kinase 4 sensor domain in complex with trans-zeatin