3t95 - Revision history

OCA at 13:21, 14 March 2024

OCA — Thu, 14 Mar 2024 13:21:25 GMT

←Older revision		Revision as of 13:21, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3t95' size='340' side='right'caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='3t95' size='340' side='right'caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Yersinia_pestis_co92~~ Yersinia pestis ~~co92~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T95 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_CO92 Yersinia pestis CO92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PAV:(2R,4S)~~-~~2-METHYL-2~~,~~3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.75Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;'>[[1tjy\|1tjy]]~~, ~~[[3ejw\|3ejw]]~~, ~~[[1tm2\|1tm2]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [https://pdbe.org/3t95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [https://www.ebi.ac.uk/pdbsum/3t95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t95 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [https://pdbe.org/3t95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [https://www.ebi.ac.uk/pdbsum/3t95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t95 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LSRB_YERPE LSRB_YERPE]] Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).	+	[https://www.uniprot.org/uniprot/LSRB_YERPE LSRB_YERPE] Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	The crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2 (AI-2; space group P2(1)2(1)2(1), unit-cell parameters a = 40.61, b = 61.03, c = 125.23 A) has been solved by molecular replacement using the structure of LsrB from Salmonella typhimurium (PDB entry 1tjy) and refined to R = 0.180 (R(free) = 0.213) at 1.75 A resolution. The electron density for bound AI-2 and the stereochemistry of the AI-2-binding site are consistent with bound AI-2 adopting the (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran conformation, just as has been observed in the crystal structures of the Salmonella typhimurium and Sinorhizobium meliloti LsrB-AI-2 complexes.	+
-		+
-	The structure of LsrB from Yersinia pestis complexed with autoinducer-2.,Kavanaugh JS, Gakhar L, Horswill AR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5., Epub 2011 Nov 29. PMID:22139152<ref>PMID:22139152</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3t95" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Yersinia pestis ~~co92~~]]	+	[[Category: Yersinia pestis CO92]]
-	[[Category: Gakhar, L]]	+	[[Category: Gakhar L]]
-	[[Category: Horswill~~, A R~~]]	+	[[Category: Horswill AR]]
-	[[Category: Kavanaugh~~, J S]]~~	+	[[Category: Kavanaugh JS]]
-	~~[[Category: Periplasmic binding protein fold]]~~	+
-	~~[[Category: Periplasmic space]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 16:48, 6 July 2022

OCA — Wed, 06 Jul 2022 16:48:14 GMT

←Older revision		Revision as of 16:48, 6 July 2022
Line 1:		Line 1:

	==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==		==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==
-	<StructureSection load='3t95' size='340' side='right' caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>	+	<StructureSection load='3t95' size='340' side='right'caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3T95 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [~~http~~://pdbe.org/3t95 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3t95 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3t95 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [https://pdbe.org/3t95 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [https://www.ebi.ac.uk/pdbsum/3t95 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t95 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LSRB_YERPE LSRB_YERPE]] Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).	+	[[https://www.uniprot.org/uniprot/LSRB_YERPE LSRB_YERPE]] Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Yersinia pestis co92]]		[[Category: Yersinia pestis co92]]
	[[Category: Gakhar, L]]		[[Category: Gakhar, L]]

OCA at 11:03, 5 August 2016

OCA — Fri, 05 Aug 2016 11:03:33 GMT

←Older revision		Revision as of 11:03, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==		==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==
	<StructureSection load='3t95' size='340' side='right' caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>		<StructureSection load='3t95' size='340' side='right' caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Yersinia_pestis~~ Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis_co92 Yersinia pestis co92]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~632~~ Yersinia pestis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=214092 Yersinia pestis CO92])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://pdbe.org/3t95 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3t95 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3t95" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Yersinia pestis]]	+	[[Category: Yersinia pestis co92]]
	[[Category: Gakhar, L]]		[[Category: Gakhar, L]]
	[[Category: Horswill, A R]]		[[Category: Horswill, A R]]

OCA at 18:16, 25 December 2014

OCA — Thu, 25 Dec 2014 18:16:20 GMT

←Older revision		Revision as of 18:16, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LSRB_YERPE LSRB_YERPE]] Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 16:
	The structure of LsrB from Yersinia pestis complexed with autoinducer-2.,Kavanaugh JS, Gakhar L, Horswill AR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5., Epub 2011 Nov 29. PMID:22139152<ref>PMID:22139152</ref>		The structure of LsrB from Yersinia pestis complexed with autoinducer-2.,Kavanaugh JS, Gakhar L, Horswill AR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5., Epub 2011 Nov 29. PMID:22139152<ref>PMID:22139152</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Yersinia pestis]]		[[Category: Yersinia pestis]]
-	[[Category: Gakhar, L.]]	+	[[Category: Gakhar, L]]
-	[[Category: Horswill, A R.]]	+	[[Category: Horswill, A R]]
-	[[Category: Kavanaugh, J S.]]	+	[[Category: Kavanaugh, J S]]
	[[Category: Periplasmic binding protein fold]]		[[Category: Periplasmic binding protein fold]]
	[[Category: Periplasmic space]]		[[Category: Periplasmic space]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 06:10, 5 June 2014

OCA — Thu, 05 Jun 2014 06:10:37 GMT

←Older revision		Revision as of 06:10, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3t95.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2==
		+	<StructureSection load='3t95' size='340' side='right' caption='[[3t95]], [[Resolution\|resolution]] 1.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3T95 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PAV:(2R,4S)-2-METHYL-2,3,3,4-TETRAHYDROXYTETRAHYDROFURAN'>PAV</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tjy\|1tjy]], [[3ejw\|3ejw]], [[1tm2\|1tm2]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lsrB, y3772, YPO0409, YP_3772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 Yersinia pestis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3t95 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t95 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3t95 RCSB], [http://www.ebi.ac.uk/pdbsum/3t95 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2 (AI-2; space group P2(1)2(1)2(1), unit-cell parameters a = 40.61, b = 61.03, c = 125.23 A) has been solved by molecular replacement using the structure of LsrB from Salmonella typhimurium (PDB entry 1tjy) and refined to R = 0.180 (R(free) = 0.213) at 1.75 A resolution. The electron density for bound AI-2 and the stereochemistry of the AI-2-binding site are consistent with bound AI-2 adopting the (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran conformation, just as has been observed in the crystal structures of the Salmonella typhimurium and Sinorhizobium meliloti LsrB-AI-2 complexes.

-	~~<!--~~	+	The structure of LsrB from Yersinia pestis complexed with autoinducer-2.,Kavanaugh JS, Gakhar L, Horswill AR Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Dec 1;67(Pt 12):1501-5., Epub 2011 Nov 29. PMID:22139152<ref>PMID:22139152</ref>
-	The ~~line below this paragraph~~, ~~containing "STRUCTURE_3t95"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded~~),	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3t95\| PDB=3t95 \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~LsrB from Yersinia pestis complexed with autoinducer-2===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22139152}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22139152 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22139152}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3t95]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022139152<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Yersinia pestis]]		[[Category: Yersinia pestis]]
	[[Category: Gakhar, L.]]		[[Category: Gakhar, L.]]

OCA at 06:59, 28 March 2012

OCA — Wed, 28 Mar 2012 06:59:31 GMT

←Older revision		Revision as of 06:59, 28 March 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3t95.png\|left\|200px]]

-	The ~~entry 3t95~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3t95", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3t95\| PDB=3t95 \| SCENE= }}

-	~~Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R.~~	+	===Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2===

-	~~Description~~: ~~Crystal~~ structure ~~of LsrB~~ from Yersinia pestis ~~complexed with autoinducer~~-2	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22139152}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22139152 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22139152}}
		+
		+	==About this Structure==
		+	[[3t95]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T95 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022139152</ref><references group="xtra"/>
		+	[[Category: Yersinia pestis]]
		+	[[Category: Gakhar, L.]]
		+	[[Category: Horswill, A R.]]
		+	[[Category: Kavanaugh, J S.]]
		+	[[Category: Periplasmic binding protein fold]]
		+	[[Category: Periplasmic space]]
		+	[[Category: Signaling protein]]

OCA at 06:02, 14 September 2011

OCA — Wed, 14 Sep 2011 06:02:26 GMT

←Older revision		Revision as of 06:02, 14 September 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3t95 is ON HOLD	+	The entry 3t95 is ON HOLD until Paper Publication

	Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R.		Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R.

	Description: Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2		Description: Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2

OCA: Protected "3t95" [edit=sysop:move=sysop]

OCA — Wed, 10 Aug 2011 05:37:50 GMT

Protected "3t95" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:37, 10 August 2011

OCA: New page: '''Unreleased structure''' The entry 3t95 is ON HOLD Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R. Description: Crystal structure of LsrB from Yersinia pestis complexed with aut...

OCA — Wed, 10 Aug 2011 05:37:49 GMT

New page: '''Unreleased structure''' The entry 3t95 is ON HOLD Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R. Description: Crystal structure of LsrB from Yersinia pestis complexed with aut...

New page

'''Unreleased structure'''

The entry 3t95 is ON HOLD

Authors: Kavanaugh, J.S., Gakhar, L., Horswill, A.R.

Description: Crystal structure of LsrB from Yersinia pestis complexed with autoinducer-2