3tco - Revision history

OCA at 13:24, 14 March 2024

OCA — Thu, 14 Mar 2024 13:24:11 GMT

←Older revision		Revision as of 13:24, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3tco' size='340' side='right'caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3tco' size='340' side='right'caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_35091 Atcc 35091~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCO FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=EDO:~~1~~,2-ETHANEDIOL'>EDO</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~trxA-~~1, ~~SSO0368 ([https:~~/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [https://pdbe.org/3tco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [https://www.ebi.ac.uk/pdbsum/3tco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tco ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [https://pdbe.org/3tco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [https://www.ebi.ac.uk/pdbsum/3tco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tco ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q980E5_SACS2 Q980E5_SACS2]
-	Structural characterizations of thioredoxins (Trxs) are important for their involvement in severe pathologies and for their stable scaffold. Here we report a combined structural and spectroscopic characterization of a Trx isolated from the hyperthermophilic archaeon Sulfolobus solfataricus (SsTrxA1). Thermal denaturation unveils that SsTrxA1 is endowed with a remarkable stability in the explored temperature range 50-105 degrees C. The structure of the oxidized form of SsTrxA1 determined at 1.9A resolution presents a number of peculiar features. Although the protein was crystallized in a slightly acid medium (pH 6.5) as many as ten intramolecular/intermolecular carboxyl-carboxylate interactions involving glutamic and aspartic acid side chains are found in three independent SsTrxA1 molecules present in the asymmetric unit. Surprisingly for a hyperthermostable protein, the structure of SsTrxA1 is characterized by the presence (a) of a very limited number of intramolecular salt bridges and (b) of a cavity nearby Cys52, a residue that is frequently a phenylananine in other members of the family. Chemical denaturation investigations carried out on SsTrxA1 and SsTrxA2 show that both proteins present a significant stability against guanidine hydrochloride, thus indicating that ionic interactions play a minor role in their stabilization. Compared to Trxs from mesophilic sources, SsTrxA1 displays a longer alpha-helix 1 and a shorter loop connecting this alpha-helix with beta-strand 2. As these features are shared with Trxs isolated from thermophilic sources, the shortening of this loop may be a general strategy adopted to stabilize this fold. This feature may be exploited for the design of hyperthermostable Trx scaffolds.	+
-		+
-	Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability.,Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L J Struct Biol. 2011 Nov 7. PMID:~~22085748<ref>PMID:22085748<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3tco" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]		*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 35091]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arcari, P]]	+	[[Category: Saccharolobus solfataricus]]
-	[[Category: Esposito, L]]	+	[[Category: Arcari P]]
-	[[Category: Lamberti, A]]	+	[[Category: Esposito L]]
-	[[Category: Masullo, M]]	+	[[Category: Lamberti A]]
-	[[Category: Ruggiero, A]]	+	[[Category: Masullo M]]
-	[[Category: Ruocco~~, M R~~]]	+	[[Category: Ruggiero A]]
-	[[Category: Vitagliano, L]]	+	[[Category: Ruocco MR]]
-	[[Category: Zagari, A]]	+	[[Category: Vitagliano L]]
-	~~[[Category: Disulfide oxidoreductase]]~~	+	[[Category: Zagari A]]
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 16:52, 6 July 2022

OCA — Wed, 06 Jul 2022 16:52:13 GMT

←Older revision		Revision as of 16:52, 6 July 2022
Line 1:		Line 1:

	==Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability==		==Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability==
-	<StructureSection load='3tco' size='340' side='right' caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='3tco' size='340' side='right'caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TCO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCO FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trxA-1, SSO0368 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trxA-1, SSO0368 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [~~http~~://pdbe.org/3tco PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tco PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tco ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [https://pdbe.org/3tco PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [https://www.ebi.ac.uk/pdbsum/3tco PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tco ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 19:		Line 19:

	==See Also==		==See Also==
-	*[[Thioredoxin\|Thioredoxin]]	+	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 35091]]		[[Category: Atcc 35091]]
		+	[[Category: Large Structures]]
	[[Category: Arcari, P]]		[[Category: Arcari, P]]
	[[Category: Esposito, L]]		[[Category: Esposito, L]]

OCA at 11:21, 10 December 2016

OCA — Sat, 10 Dec 2016 11:21:25 GMT

←Older revision		Revision as of 11:21, 10 December 2016
Line 1:		Line 1:
		+
	==Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability==		==Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability==
	<StructureSection load='3tco' size='340' side='right' caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='3tco' size='340' side='right' caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sulfolobus_solfataricus Sulfolobus solfataricus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCO FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trxA-1, SSO0368 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ~~Sulfolobus solfataricus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trxA-1, SSO0368 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [http://www.ebi.ac.uk/pdbsum/3tco PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [http://pdbe.org/3tco PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [http://www.ebi.ac.uk/pdbsum/3tco PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tco ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tco" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 22:		Line 24:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Sulfolobus solfataricus~~]]	+	[[Category: Atcc 35091]]
	[[Category: Arcari, P]]		[[Category: Arcari, P]]
	[[Category: Esposito, L]]		[[Category: Esposito, L]]

OCA at 17:25, 9 December 2014

OCA — Tue, 09 Dec 2014 17:25:33 GMT

←Older revision		Revision as of 17:25, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3tco.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability==
		+	<StructureSection load='3tco' size='340' side='right' caption='[[3tco]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCO FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trxA-1, SSO0368 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 Sulfolobus solfataricus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tco FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tco OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tco RCSB], [http://www.ebi.ac.uk/pdbsum/3tco PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Structural characterizations of thioredoxins (Trxs) are important for their involvement in severe pathologies and for their stable scaffold. Here we report a combined structural and spectroscopic characterization of a Trx isolated from the hyperthermophilic archaeon Sulfolobus solfataricus (SsTrxA1). Thermal denaturation unveils that SsTrxA1 is endowed with a remarkable stability in the explored temperature range 50-105 degrees C. The structure of the oxidized form of SsTrxA1 determined at 1.9A resolution presents a number of peculiar features. Although the protein was crystallized in a slightly acid medium (pH 6.5) as many as ten intramolecular/intermolecular carboxyl-carboxylate interactions involving glutamic and aspartic acid side chains are found in three independent SsTrxA1 molecules present in the asymmetric unit. Surprisingly for a hyperthermostable protein, the structure of SsTrxA1 is characterized by the presence (a) of a very limited number of intramolecular salt bridges and (b) of a cavity nearby Cys52, a residue that is frequently a phenylananine in other members of the family. Chemical denaturation investigations carried out on SsTrxA1 and SsTrxA2 show that both proteins present a significant stability against guanidine hydrochloride, thus indicating that ionic interactions play a minor role in their stabilization. Compared to Trxs from mesophilic sources, SsTrxA1 displays a longer alpha-helix 1 and a shorter loop connecting this alpha-helix with beta-strand 2. As these features are shared with Trxs isolated from thermophilic sources, the shortening of this loop may be a general strategy adopted to stabilize this fold. This feature may be exploited for the design of hyperthermostable Trx scaffolds.

-	~~{{STRUCTURE_3tco\| PDB=3tco \| SCENE= }}~~	+	Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability.,Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L J Struct Biol. 2011 Nov 7. PMID:22085748<ref>PMID:22085748</ref>

-	~~===Crystallographic and spectroscopic characterization~~ of ~~Sulfolobus solfataricus TrxA1 provide insights into~~ the ~~determinants of thioredoxin fold stability===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22085748}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3tco]] is a 3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].~~	+

	==See Also==		==See Also==
	*[[Thioredoxin\|Thioredoxin]]		*[[Thioredoxin\|Thioredoxin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022085748<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Sulfolobus solfataricus]]		[[Category: Sulfolobus solfataricus]]
-	[[Category: Arcari, P.]]	+	[[Category: Arcari, P]]
-	[[Category: Esposito, L.]]	+	[[Category: Esposito, L]]
-	[[Category: Lamberti, A.]]	+	[[Category: Lamberti, A]]
-	[[Category: Masullo, M.]]	+	[[Category: Masullo, M]]
-	[[Category: Ruggiero, A.]]	+	[[Category: Ruggiero, A]]
-	[[Category: Ruocco, M R.]]	+	[[Category: Ruocco, M R]]
-	[[Category: Vitagliano, L.]]	+	[[Category: Vitagliano, L]]
-	[[Category: Zagari, A.]]	+	[[Category: Zagari, A]]
	[[Category: Disulfide oxidoreductase]]		[[Category: Disulfide oxidoreductase]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 09:30, 20 October 2012

OCA — Sat, 20 Oct 2012 09:30:14 GMT

←Older revision		Revision as of 09:30, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[3tco]] is a 3 chain structure ~~of [[Thioredoxin]]~~ with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].	+	[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].

	==See Also==		==See Also==

OCA at 23:04, 25 July 2012

OCA — Wed, 25 Jul 2012 23:04:10 GMT

←Older revision		Revision as of 23:04, 25 July 2012
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	[[Image:3tco.png\|left\|200px]]		[[Image:3tco.png\|left\|200px]]

-	<!--
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-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_3tco\| PDB=3tco \| SCENE= }}		{{STRUCTURE_3tco\| PDB=3tco \| SCENE= }}

	===Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability===		===Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22085748}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22085748 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_22085748}}		{{ABSTRACT_PUBMED_22085748}}

	==About this Structure==		==About this Structure==
-	[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].	+	[[3tco]] is a 3 chain structure of [[Thioredoxin]] with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].
		+
		+	==See Also==
		+	*[[Thioredoxin\|Thioredoxin]]

	==Reference==		==Reference==

OCA at 08:10, 7 December 2011

OCA — Wed, 07 Dec 2011 08:10:36 GMT

←Older revision		Revision as of 08:10, 7 December 2011
Line 1:		Line 1:
-	[[Image:3tco.~~jpg~~\|left\|200px]]	+	[[Image:3tco.png\|left\|200px]]

	<!--		<!--

OCA at 06:20, 30 November 2011

OCA — Wed, 30 Nov 2011 06:20:07 GMT

←Older revision		Revision as of 06:20, 30 November 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tco.jpg\|left\|200px]]

-	The ~~entry 3tco~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3tco", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3tco\| PDB=3tco \| SCENE= }}

-	~~Authors: Esposito, L., Ruggiero, A., Masullo, M., Ruocco, M.R., Lamberti, A., Arcari, P., Zagari, A., Vitagliano, L.~~	+	===Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability===

-	~~Description~~: ~~Crystallographic and spectroscopic characterization of~~ Sulfolobus solfataricus ~~TrxA1 provide insights into the determinants of thioredoxin fold stability~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22085748}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22085748 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22085748}}
		+
		+	==About this Structure==
		+	[[3tco]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCO OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022085748</ref><references group="xtra"/>
		+	[[Category: Sulfolobus solfataricus]]
		+	[[Category: Arcari, P.]]
		+	[[Category: Esposito, L.]]
		+	[[Category: Lamberti, A.]]
		+	[[Category: Masullo, M.]]
		+	[[Category: Ruggiero, A.]]
		+	[[Category: Ruocco, M R.]]
		+	[[Category: Vitagliano, L.]]
		+	[[Category: Zagari, A.]]
		+	[[Category: Disulfide oxidoreductase]]
		+	[[Category: Oxidoreductase]]

OCA at 11:46, 16 November 2011

OCA — Wed, 16 Nov 2011 11:46:27 GMT

←Older revision		Revision as of 11:46, 16 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tco is ON HOLD	+	The entry 3tco is ON HOLD until Paper Publication

	Authors: Esposito, L., Ruggiero, A., Masullo, M., Ruocco, M.R., Lamberti, A., Arcari, P., Zagari, A., Vitagliano, L.		Authors: Esposito, L., Ruggiero, A., Masullo, M., Ruocco, M.R., Lamberti, A., Arcari, P., Zagari, A., Vitagliano, L.

	Description: Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability		Description: Crystallographic and spectroscopic characterization of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability

OCA: Protected "3tco" [edit=sysop:move=sysop]

OCA — Wed, 17 Aug 2011 05:57:25 GMT

Protected "3tco" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:57, 17 August 2011