3tcy - Revision history

OCA at 13:24, 14 March 2024

OCA — Thu, 14 Mar 2024 13:24:48 GMT

←Older revision		Revision as of 13:24, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3tcy' size='340' side='right'caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3tcy' size='340' side='right'caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"chromobacterium_janthinum"_(zopf)_ford_1927 "chromobacterium janthinum" (zopf) ford 1927~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCY FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>~~, ~~<scene name='pdbligand=EDO:~~1~~,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>phhA, CV_3180 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~536~~ "~~Chromobacterium janthinum~~" (~~Zopf~~) ~~Ford 1927])</td~~></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [https://pdbe.org/3tcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [https://www.ebi.ac.uk/pdbsum/3tcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcy ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [https://pdbe.org/3tcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [https://www.ebi.ac.uk/pdbsum/3tcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcy ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/PH4H_CHRVO PH4H_CHRVO]
-	Phenylalanine hydroxylase (PAH) is a non-heme iron enzyme that catalyzes oxidation of phenylalanine to tyrosine, a reaction that must be kept under tight regulatory control. Mammalian PAH has a regulatory domain in which binding of the substrate leads to allosteric activation of the enzyme. However, the existence of PAH regulation in evolutionarily distant organisms, for example some bacteria in which it occurs, has so far been underappreciated. In an attempt to crystallographically characterize substrate binding by PAH from Chromobacterium violaceum, a single-domain monomeric enzyme, electron density for phenylalanine was observed at a distal site 15.7 A from the active site. Isothermal titration calorimetry (ITC) experiments revealed a dissociation constant of 24 +/- 1.1 muM for phenylalanine. Under the same conditions, ITC revealed no detectable binding for alanine, tyrosine, or isoleucine, indicating the distal site may be selective for phenylalanine. Point mutations of amino acid residues in the distal site that contact phenylalanine (F258A, Y155A, T254A) led to impaired binding, consistent with the presence of distal site binding in solution. Although kinetic analysis revealed that the distal site mutants suffer discernible loss of their catalytic activity, X-ray crystallographic analysis of Y155A and F258A, the two mutants with the most noticeable decrease in activity, revealed no discernible change in the structure of their active sites, suggesting that the effect of distal binding may result from protein dynamics in solution.	+
-		+
-	~~An additional substrate binding site in a bacterial phenylalanine hydroxylase.,Ronau JA, Paul LN, Fuchs JE, Corn IR, Wagner KT, Liedl KR, Abu-Omar MM, Das C Eur Biophys J. 2013 Jul 17. PMID~~:~~23860686<ref>PMID:23860686<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3tcy" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Hydroxylases 3D structures\|Hydroxylases 3D structures]]		*[[Hydroxylases 3D structures\|Hydroxylases 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chromobacterium violaceum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Phenylalanine 4-monooxygenase]]~~	+	[[Category: Abu-Omar MM]]
-	[[Category: Abu-Omar~~, M M~~]]	+	[[Category: Das C]]
-	[[Category: Das, C]]	+	[[Category: Ronau JA]]
-	[[Category: Ronau~~, J A]]~~	+
-	~~[[Category: Distal site]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Phenylalanine bound structure]]~~	+
-	~~[[Category: Phenylalanine hydroxylase]]~~	+
-	~~[[Category: Substrate-protein complex~~]]	+

OCA at 16:52, 6 July 2022

OCA — Wed, 06 Jul 2022 16:52:32 GMT

←Older revision		Revision as of 16:52, 6 July 2022
Line 3:		Line 3:
	<StructureSection load='3tcy' size='340' side='right'caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='3tcy' size='340' side='right'caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"chromobacterium_janthinum"_(zopf)_ford_1927 "chromobacterium janthinum" (zopf) ford 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"chromobacterium_janthinum"_(zopf)_ford_1927 "chromobacterium janthinum" (zopf) ford 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TCY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536 "Chromobacterium janthinum" (Zopf) Ford 1927])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536 "Chromobacterium janthinum" (Zopf) Ford 1927])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [~~http~~://pdbe.org/3tcy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tcy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [https://pdbe.org/3tcy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [https://www.ebi.ac.uk/pdbsum/3tcy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:53, 20 November 2019

OCA — Wed, 20 Nov 2019 15:53:23 GMT

←Older revision		Revision as of 15:53, 20 November 2019
Line 1:		Line 1:
		+
	==Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site==		==Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site==
-	<StructureSection load='3tcy' size='340' side='right' caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='3tcy' size='340' side='right'caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Chromobacterium_violaceum Chromobacterium violaceum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"chromobacterium_janthinum"_(zopf)_ford_1927 "chromobacterium janthinum" (zopf) ford 1927]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536 Chromobacterium ~~violaceum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536 "Chromobacterium janthinum" (Zopf) Ford 1927])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [http://www.ebi.ac.uk/pdbsum/3tcy PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [http://pdbe.org/3tcy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [http://www.ebi.ac.uk/pdbsum/3tcy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tcy ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tcy" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[~~Phenylalanine hydroxylase~~\|~~Phenylalanine hydroxylase~~]]	+	*[[Hydroxylases 3D structures\|Hydroxylases 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Chromobacterium violaceum~~]]	+	[[Category: Large Structures]]
	[[Category: Phenylalanine 4-monooxygenase]]		[[Category: Phenylalanine 4-monooxygenase]]
	[[Category: Abu-Omar, M M]]		[[Category: Abu-Omar, M M]]

OCA at 10:28, 4 January 2015

OCA — Sun, 04 Jan 2015 10:28:01 GMT

←Older revision		Revision as of 10:28, 4 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3tcy\| PDB=3tcy \| SCENE= }}~~	+	==Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site==
-	===Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site===	+	<StructureSection load='3tcy' size='340' side='right' caption='[[3tcy]], [[Resolution\|resolution]] 1.55Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23860686}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TCY FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">phhA, CV_3180 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=536 Chromobacterium violaceum])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phenylalanine_4-monooxygenase Phenylalanine 4-monooxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.16.1 1.14.16.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tcy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tcy RCSB], [http://www.ebi.ac.uk/pdbsum/3tcy PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phenylalanine hydroxylase (PAH) is a non-heme iron enzyme that catalyzes oxidation of phenylalanine to tyrosine, a reaction that must be kept under tight regulatory control. Mammalian PAH has a regulatory domain in which binding of the substrate leads to allosteric activation of the enzyme. However, the existence of PAH regulation in evolutionarily distant organisms, for example some bacteria in which it occurs, has so far been underappreciated. In an attempt to crystallographically characterize substrate binding by PAH from Chromobacterium violaceum, a single-domain monomeric enzyme, electron density for phenylalanine was observed at a distal site 15.7 A from the active site. Isothermal titration calorimetry (ITC) experiments revealed a dissociation constant of 24 +/- 1.1 muM for phenylalanine. Under the same conditions, ITC revealed no detectable binding for alanine, tyrosine, or isoleucine, indicating the distal site may be selective for phenylalanine. Point mutations of amino acid residues in the distal site that contact phenylalanine (F258A, Y155A, T254A) led to impaired binding, consistent with the presence of distal site binding in solution. Although kinetic analysis revealed that the distal site mutants suffer discernible loss of their catalytic activity, X-ray crystallographic analysis of Y155A and F258A, the two mutants with the most noticeable decrease in activity, revealed no discernible change in the structure of their active sites, suggesting that the effect of distal binding may result from protein dynamics in solution.

-	~~==About this Structure==~~	+	An additional substrate binding site in a bacterial phenylalanine hydroxylase.,Ronau JA, Paul LN, Fuchs JE, Corn IR, Wagner KT, Liedl KR, Abu-Omar MM, Das C Eur Biophys J. 2013 Jul 17. PMID:23860686<ref>PMID:23860686</ref>
-	~~[[3tcy]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3TCY OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Phenylalanine hydroxylase\|Phenylalanine hydroxylase]]		*[[Phenylalanine hydroxylase\|Phenylalanine hydroxylase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:023860686</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Chromobacterium violaceum]]		[[Category: Chromobacterium violaceum]]
	[[Category: Phenylalanine 4-monooxygenase]]		[[Category: Phenylalanine 4-monooxygenase]]
-	[[Category: Abu-Omar, M M.]]	+	[[Category: Abu-Omar, M M]]
-	[[Category: Das, C.]]	+	[[Category: Das, C]]
-	[[Category: Ronau, J A.]]	+	[[Category: Ronau, J A]]
	[[Category: Distal site]]		[[Category: Distal site]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 03:25, 1 August 2013

OCA — Thu, 01 Aug 2013 03:25:06 GMT

←Older revision		Revision as of 03:25, 1 August 2013
Line 1:		Line 1:
-	[[Image:3tcy.jpg\|left\|200px]]
-
	{{STRUCTURE_3tcy\| PDB=3tcy \| SCENE= }}		{{STRUCTURE_3tcy\| PDB=3tcy \| SCENE= }}
-
	===Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site===		===Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site===
-		+	{{ABSTRACT_PUBMED_23860686}}

	==About this Structure==		==About this Structure==
	[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA].		[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA].
		+
		+	==See Also==
		+	*[[Phenylalanine hydroxylase\|Phenylalanine hydroxylase]]
		+
		+	==Reference==
		+	<ref group="xtra">PMID:023860686</ref><references group="xtra"/><references/>
	[[Category: Chromobacterium violaceum]]		[[Category: Chromobacterium violaceum]]
	[[Category: Phenylalanine 4-monooxygenase]]		[[Category: Phenylalanine 4-monooxygenase]]

OCA at 06:00, 22 August 2012

OCA — Wed, 22 Aug 2012 06:00:45 GMT

←Older revision		Revision as of 06:00, 22 August 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tcy.jpg\|left\|200px]]

-	~~The entry~~ 3tcy ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3tcy\| PDB=3tcy \| SCENE= }}

-	~~Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.~~	+	===Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site===

-	~~Description: Crystallographic~~ structure ~~of phenylalanine hydroxylase~~ from Chromobacterium violaceum ~~(cPAH) bound to phenylalanine in a site distal to the active~~ site	+
		+	==About this Structure==
		+	[[3tcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Chromobacterium_violaceum Chromobacterium violaceum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TCY OCA].
		+	[[Category: Chromobacterium violaceum]]
		+	[[Category: Phenylalanine 4-monooxygenase]]
		+	[[Category: Abu-Omar, M M.]]
		+	[[Category: Das, C.]]
		+	[[Category: Ronau, J A.]]
		+	[[Category: Distal site]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Phenylalanine bound structure]]
		+	[[Category: Phenylalanine hydroxylase]]
		+	[[Category: Substrate-protein complex]]

OCA at 06:00, 14 March 2012

OCA — Wed, 14 Mar 2012 06:00:32 GMT

←Older revision		Revision as of 06:00, 14 March 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tcy is ON HOLD	+	The entry 3tcy is ON HOLD until Paper Publication

	Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.		Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.

	Description: Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site		Description: Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site

OCA: Protected "3tcy" [edit=sysop:move=sysop]

OCA — Wed, 17 Aug 2011 05:57:40 GMT

Protected "3tcy" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:57, 17 August 2011

OCA: New page: '''Unreleased structure''' The entry 3tcy is ON HOLD Authors: Ronau, J.A., Abu-Omar, M.M., Das, C. Description: Crystallographic structure of phenylalanine hydroxylase from Chromobacte...

OCA — Wed, 17 Aug 2011 05:57:39 GMT

New page: '''Unreleased structure''' The entry 3tcy is ON HOLD Authors: Ronau, J.A., Abu-Omar, M.M., Das, C. Description: Crystallographic structure of phenylalanine hydroxylase from Chromobacte...

New page

'''Unreleased structure'''

The entry 3tcy is ON HOLD

Authors: Ronau, J.A., Abu-Omar, M.M., Das, C.

Description: Crystallographic structure of phenylalanine hydroxylase from Chromobacterium violaceum (cPAH) bound to phenylalanine in a site distal to the active site