3tf1 - Revision history

OCA at 13:26, 14 March 2024

OCA — Thu, 14 Mar 2024 13:26:03 GMT

←Older revision		Revision as of 13:26, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3tf1' size='340' side='right'caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3tf1' size='340' side='right'caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~As_1~~.~~2430 As 1~~.~~2430~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis Caldanaerobacter subterraneus subsp. tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.0369Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 AS 1.2430])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [https://pdbe.org/3tf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [https://www.ebi.ac.uk/pdbsum/3tf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tf1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [https://pdbe.org/3tf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [https://www.ebi.ac.uk/pdbsum/3tf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tf1 ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q8RBX6_CALS4 Q8RBX6_CALS4]
-	Interior topological features, such as pockets and channels, have evolved in proteins to regulate biological functions by facilitating the diffusion of biomolecules. Decades of research using the globins as model heme proteins have clearly highlighted the importance of gas pockets around the heme in controlling the capture and release of O(2). However, much less is known about how ligand migration contributes to the diverse functions of other heme protein scaffolds. Heme nitric oxide/oxygen binding (H-NOX) domains are a conserved family of gas-sensing heme proteins with a divergent fold that are critical to numerous signaling pathways. Utilizing X-ray crystallography with xenon, a tunnel network has been shown to serve as a molecular pathway for ligand diffusion. Structure-guided mutagenesis results show that the tunnels have unexpected effects on gas-sensing properties in H-NOX domains. The findings provide insights on how the flux of biomolecules through protein scaffolds modulates protein chemistry.	+
-		+
-	~~Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.,Winter MB, Herzik MA Jr, Kuriyan J, Marletta MA Proc Natl Acad Sci U S A. 2011 Oct 25;108(43)~~:~~E881-9. Epub 2011 Oct 12. PMID:21997213<ref>PMID:21997213<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®~~/~~PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3tf1" style="background-color:#fffaf0;"><~~/~~div>~~	+

	==See Also==		==See Also==
	*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]		*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~As 1 2430~~]]	+	[[Category: Caldanaerobacter subterraneus subsp. tengcongensis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Herzik~~, M A~~]]	+	[[Category: Herzik Jr MA]]
-	[[Category: Kuriyan, J]]	+	[[Category: Kuriyan J]]
-	[[Category: Marletta~~, M A~~]]	+	[[Category: Marletta MA]]
-	[[Category: Winter~~, M B]]~~	+	[[Category: Winter MB]]
-	~~[[Category: Gas binding]]~~	+
-	~~[[Category: Heme-based methyl-accepting chemotaxis protein]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 16:55, 6 July 2022

OCA — Wed, 06 Jul 2022 16:55:15 GMT

←Older revision		Revision as of 16:55, 6 July 2022
Line 1:		Line 1:

	==Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon==		==Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon==
-	<StructureSection load='3tf1' size='340' side='right' caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>	+	<StructureSection load='3tf1' size='340' side='right'caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/As_1.2430 As 1.2430]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/As_1.2430 As 1.2430]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 AS 1.2430])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 AS 1.2430])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [~~http~~://pdbe.org/3tf1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tf1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tf1 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [https://pdbe.org/3tf1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [https://www.ebi.ac.uk/pdbsum/3tf1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tf1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Chemotaxis protein\|Chemotaxis protein]]	+	*[[Chemotaxis protein 3D structures\|Chemotaxis protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 26:
	</StructureSection>		</StructureSection>
	[[Category: As 1 2430]]		[[Category: As 1 2430]]
		+	[[Category: Large Structures]]
	[[Category: Herzik, M A]]		[[Category: Herzik, M A]]
	[[Category: Kuriyan, J]]		[[Category: Kuriyan, J]]

OCA at 13:41, 5 August 2016

OCA — Fri, 05 Aug 2016 13:41:38 GMT

←Older revision		Revision as of 13:41, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon==		==Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon==
	<StructureSection load='3tf1' size='340' side='right' caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>		<StructureSection load='3tf1' size='340' side='right' caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Caldanaerobacter_subterraneus_subsp~~.~~_tengcongensis Caldanaerobacter subterraneus subsp~~. ~~tengcongensis~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/As_1.2430 As 1.2430]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 ~~Caldanaerobacter subterraneus subsp~~. ~~tengcongensis~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 AS 1.2430])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [http://www.ebi.ac.uk/pdbsum/3tf1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [http://pdbe.org/3tf1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [http://www.ebi.ac.uk/pdbsum/3tf1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tf1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tf1" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 23:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caldanaerobacter subterraneus subsp. tengcongensis~~]]	+	[[Category: As 1 2430]]
	[[Category: Herzik, M A]]		[[Category: Herzik, M A]]
	[[Category: Kuriyan, J]]		[[Category: Kuriyan, J]]

OCA at 08:35, 18 December 2014

OCA — Thu, 18 Dec 2014 08:35:52 GMT

←Older revision		Revision as of 08:35, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3tf1\| PDB=3tf1 \| SCENE= }}~~	+	==Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon==
-	===Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon===	+	<StructureSection load='3tf1' size='340' side='right' caption='[[3tf1]], [[Resolution\|resolution]] 2.04Å' scene=''>
-	~~{{ABSTRACT_PUBMED_21997213}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis Caldanaerobacter subterraneus subsp. tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TF1 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1u4h\|1u4h]], [[1u55\|1u55]], [[1u56\|1u56]], [[3tf0\|3tf0]], [[3tf8\|3tf8]], [[3tf9\|3tf9]], [[3tfa\|3tfa]], [[3tfd\|3tfd]], [[3tfe\|3tfe]], [[3tff\|3tff]], [[3tfg\|3tfg]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tar4, TTE0680 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119072 Caldanaerobacter subterraneus subsp. tengcongensis])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tf1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tf1 RCSB], [http://www.ebi.ac.uk/pdbsum/3tf1 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Interior topological features, such as pockets and channels, have evolved in proteins to regulate biological functions by facilitating the diffusion of biomolecules. Decades of research using the globins as model heme proteins have clearly highlighted the importance of gas pockets around the heme in controlling the capture and release of O(2). However, much less is known about how ligand migration contributes to the diverse functions of other heme protein scaffolds. Heme nitric oxide/oxygen binding (H-NOX) domains are a conserved family of gas-sensing heme proteins with a divergent fold that are critical to numerous signaling pathways. Utilizing X-ray crystallography with xenon, a tunnel network has been shown to serve as a molecular pathway for ligand diffusion. Structure-guided mutagenesis results show that the tunnels have unexpected effects on gas-sensing properties in H-NOX domains. The findings provide insights on how the flux of biomolecules through protein scaffolds modulates protein chemistry.

-	~~==About this Structure==~~	+	Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain.,Winter MB, Herzik MA Jr, Kuriyan J, Marletta MA Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E881-9. Epub 2011 Oct 12. PMID:21997213<ref>PMID:21997213</ref>
-	~~[[3tf1]] is~~ a ~~2 chain structure with sequence from [http:~~/~~/en~~.~~wikipedia~~.~~org/wiki/Caldanaerobacter_subterraneus_subsp~~.~~_tengcongensis Caldanaerobacter subterraneus subsp~~. ~~tengcongensis]. Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3TF1 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Chemotaxis protein\|Chemotaxis protein]]		*[[Chemotaxis protein\|Chemotaxis protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:021997213<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Caldanaerobacter subterraneus subsp. tengcongensis]]		[[Category: Caldanaerobacter subterraneus subsp. tengcongensis]]
-	[[Category: Herzik, M A.]]	+	[[Category: Herzik, M A]]
-	[[Category: Kuriyan, J.]]	+	[[Category: Kuriyan, J]]
-	[[Category: Marletta, M A.]]	+	[[Category: Marletta, M A]]
-	[[Category: Winter, M B.]]	+	[[Category: Winter, M B]]
	[[Category: Gas binding]]		[[Category: Gas binding]]
	[[Category: Heme-based methyl-accepting chemotaxis protein]]		[[Category: Heme-based methyl-accepting chemotaxis protein]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 09:24, 11 March 2013

OCA — Mon, 11 Mar 2013 09:24:02 GMT

←Older revision		Revision as of 09:24, 11 March 2013
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-	[[Image:3tf1.jpg\|left\|200px]]
-
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	{{STRUCTURE_3tf1\| PDB=3tf1 \| SCENE= }}		{{STRUCTURE_3tf1\| PDB=3tf1 \| SCENE= }}
-
	===Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon===		===Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_21997213}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 21997213 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_21997213}}		{{ABSTRACT_PUBMED_21997213}}

	==About this Structure==		==About this Structure==
	[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis Caldanaerobacter subterraneus subsp. tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA].		[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis Caldanaerobacter subterraneus subsp. tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA].
		+
		+	==See Also==
		+	*[[Chemotaxis protein\|Chemotaxis protein]]

	==Reference==		==Reference==

OCA at 11:37, 9 November 2011

OCA — Wed, 09 Nov 2011 11:37:06 GMT

←Older revision		Revision as of 11:37, 9 November 2011
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tf1.jpg\|left\|200px]]

-	The ~~entry 3tf1~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3tf1", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3tf1\| PDB=3tf1 \| SCENE= }}

-	~~Authors: Winter, M.B., Herzik Jr., M.A., Kuriyan, J., Marletta, M.A~~.	+	===Crystal structure of an H-NOX protein from T. tengcongensis under 6 atm of xenon===

-	~~Description~~: ~~Crystal structure of~~ a ~~gas binding protein~~ from T. tengcongensis ~~under 6 atm of xenon~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_21997213}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 21997213 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_21997213}}
		+
		+	==About this Structure==
		+	[[3tf1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caldanaerobacter_subterraneus_subsp._tengcongensis Caldanaerobacter subterraneus subsp. tengcongensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TF1 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:021997213</ref><references group="xtra"/>
		+	[[Category: Caldanaerobacter subterraneus subsp. tengcongensis]]
		+	[[Category: Herzik, M A.]]
		+	[[Category: Kuriyan, J.]]
		+	[[Category: Marletta, M A.]]
		+	[[Category: Winter, M B.]]
		+	[[Category: Gas binding]]
		+	[[Category: Heme-based methyl-accepting chemotaxis protein]]
		+	[[Category: Signaling protein]]

OCA at 05:14, 28 September 2011

OCA — Wed, 28 Sep 2011 05:14:12 GMT

←Older revision		Revision as of 05:14, 28 September 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tf1 is ON HOLD	+	The entry 3tf1 is ON HOLD until Paper Publication

	Authors: Winter, M.B., Herzik Jr., M.A., Kuriyan, J., Marletta, M.A.		Authors: Winter, M.B., Herzik Jr., M.A., Kuriyan, J., Marletta, M.A.

	Description: Crystal structure of a gas binding protein from T. tengcongensis under 6 atm of xenon		Description: Crystal structure of a gas binding protein from T. tengcongensis under 6 atm of xenon

OCA at 06:24, 31 August 2011

OCA — Wed, 31 Aug 2011 06:24:04 GMT

←Older revision		Revision as of 06:24, 31 August 2011
Line 3:		Line 3:
	The entry 3tf1 is ON HOLD		The entry 3tf1 is ON HOLD

-	Authors: Winter, M.B., Herzik Jr, M.A., Kuriyan, J., Marletta, M.A.	+	Authors: Winter, M.B., Herzik Jr., M.A., Kuriyan, J., Marletta, M.A.

	Description: Crystal structure of a gas binding protein from T. tengcongensis under 6 atm of xenon		Description: Crystal structure of a gas binding protein from T. tengcongensis under 6 atm of xenon

OCA: Protected "3tf1" [edit=sysop:move=sysop]

OCA — Wed, 24 Aug 2011 07:11:41 GMT

Protected "3tf1" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:11, 24 August 2011

OCA: New page: '''Unreleased structure''' The entry 3tf1 is ON HOLD Authors: Winter, M.B., Herzik Jr, M.A., Kuriyan, J., Marletta, M.A. Description: Crystal structure of a gas binding protein from T....

OCA — Wed, 24 Aug 2011 07:11:40 GMT

New page: '''Unreleased structure''' The entry 3tf1 is ON HOLD Authors: Winter, M.B., Herzik Jr, M.A., Kuriyan, J., Marletta, M.A. Description: Crystal structure of a gas binding protein from T....

New page

'''Unreleased structure'''

The entry 3tf1 is ON HOLD

Authors: Winter, M.B., Herzik Jr, M.A., Kuriyan, J., Marletta, M.A.

Description: Crystal structure of a gas binding protein from T. tengcongensis under 6 atm of xenon