3tlj - Revision history

OCA at 10:09, 1 March 2024

OCA — Fri, 01 Mar 2024 10:09:51 GMT

←Older revision		Revision as of 10:09, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3tlj' size='340' side='right'caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3tlj' size='340' side='right'caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pyrfu Pyrfu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>~~, ~~<scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">PF1002 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [https://pdbe.org/3tlj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [https://www.ebi.ac.uk/pdbsum/3tlj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [https://pdbe.org/3tlj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [https://www.ebi.ac.uk/pdbsum/3tlj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlj ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/TRM14_PYRFU TRM14_PYRFU] S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the methylation of the guanosine nucleotide at position 6 (m2G6) in tRNA(Phe).<ref>PMID:22337946</ref> <ref>PMID:22362751</ref>
-	~~Methyltransferases (MTases) form a major class of tRNA-modifying enzymes needed for the proper functioning of tRNA. Recently, RNA MTases from the TrmN~~/~~Trm14 family that are present in Archaea, Bacteria and Eukaryota have been shown to specifically modify tRNA(Phe) at guanosine 6 in the tRNA acceptor stem~~. ~~Here, we report the first X-ray crystal structures of the tRNA m(2)G6 (N(2)-methylguanosine) MTase (TTC)TrmN from Thermus thermophilus and its ortholog (Pf)Trm14 from Pyrococcus furiosus~~. ~~Structures of (Pf)Trm14 were solved in complex with the methyl donor~~ S-adenosyl-l-methionine ~~(SAM or AdoMet), as well as the reaction product S~~-~~adenosyl-homocysteine (SAH or AdoHcy) and~~ the ~~inhibitor sinefungin. (TTC)TrmN and (Pf)Trm14 consist~~ of ~~an N-terminal THUMP domain fused to a catalytic Rossmann-fold MTase~~ (~~RFM~~) domain. These results represent the first crystallographic structure analysis of proteins containing both THUMP and RFM domain, and hence provide further insight in the contribution of the THUMP domain in tRNA recognition and catalysis. Electrostatics and conservation calculations suggest a main tRNA binding surface in a groove between the THUMP domain and the MTase domain. This is further supported by a docking model of TrmN in ~~complex with~~ tRNA(Phe) ~~of T~~. ~~thermophilus and via site-directed mutagenesis.~~	+
-		+
-	Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.,Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versees W Nucleic Acids Res. 2012 Feb 22. PMID:22362751<ref>PMID:~~22362751~~</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.~~<br>	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3tlj" style="background-color~~:~~#fffaf0;">~~</~~div~~>	+

	==See Also==		==See Also==
Line 26:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pyrfu~~]]	+	[[Category: Pyrococcus furiosus DSM 3638]]
-	[[Category: Bujnicki~~, J M~~]]	+	[[Category: Bujnicki JM]]
-	[[Category: Droogmans, L]]	+	[[Category: Droogmans L]]
-	[[Category: Fislage, M]]	+	[[Category: Fislage M]]
-	[[Category: Roovers, M]]	+	[[Category: Roovers M]]
-	[[Category: Tuszynska, I]]	+	[[Category: Tuszynska I]]
-	[[Category: Versees, W]]	+	[[Category: Versees W]]
-	~~[[Category: Methyltransferase]]~~	+
-	~~[[Category: Rossmann fold]]~~	+
-	~~[[Category: Thump domain]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Trna methyltransferase~~]]	+

OCA at 17:03, 6 July 2022

OCA — Wed, 06 Jul 2022 17:03:13 GMT

←Older revision		Revision as of 17:03, 6 July 2022
Line 1:		Line 1:

	==Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine==		==Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine==
-	<StructureSection load='3tlj' size='340' side='right' caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='3tlj' size='340' side='right'caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF1002 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF1002 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [~~http~~://pdbe.org/3tlj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tlj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [https://pdbe.org/3tlj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [https://www.ebi.ac.uk/pdbsum/3tlj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[TRNA methyltransferase\|TRNA methyltransferase]]	+	*[[TRNA methyltransferase 3D structures\|TRNA methyltransferase 3D structures]]
-	*[[TRNA:m2G6 methyltransferase TrmN/Trm14\|TRNA:m2G6 methyltransferase TrmN/Trm14]]	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pyrfu]]		[[Category: Pyrfu]]
	[[Category: Bujnicki, J M]]		[[Category: Bujnicki, J M]]

OCA at 07:55, 11 August 2016

OCA — Thu, 11 Aug 2016 07:55:26 GMT

←Older revision		Revision as of 07:55, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine==		==Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine==
	<StructureSection load='3tlj' size='340' side='right' caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='3tlj' size='340' side='right' caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus Pyrococcus furiosus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF1002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~2261 Pyrococcus furiosus~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF1002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [http://www.ebi.ac.uk/pdbsum/3tlj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [http://pdbe.org/3tlj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [http://www.ebi.ac.uk/pdbsum/3tlj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tlj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tlj" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrococcus furiosus~~]]	+	[[Category: Pyrfu]]
	[[Category: Bujnicki, J M]]		[[Category: Bujnicki, J M]]
	[[Category: Droogmans, L]]		[[Category: Droogmans, L]]

OCA at 13:04, 5 January 2015

OCA — Mon, 05 Jan 2015 13:04:56 GMT

←Older revision		Revision as of 13:04, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}~~	+	==Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine==
-	===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===	+	<StructureSection load='3tlj' size='340' side='right' caption='[[3tlj]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_22362751}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TLJ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3tm4\|3tm4]], [[3tm5\|3tm5]], [[3tma\|3tma]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF1002 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2261 Pyrococcus furiosus])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tlj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tlj RCSB], [http://www.ebi.ac.uk/pdbsum/3tlj PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Methyltransferases (MTases) form a major class of tRNA-modifying enzymes needed for the proper functioning of tRNA. Recently, RNA MTases from the TrmN/Trm14 family that are present in Archaea, Bacteria and Eukaryota have been shown to specifically modify tRNA(Phe) at guanosine 6 in the tRNA acceptor stem. Here, we report the first X-ray crystal structures of the tRNA m(2)G6 (N(2)-methylguanosine) MTase (TTC)TrmN from Thermus thermophilus and its ortholog (Pf)Trm14 from Pyrococcus furiosus. Structures of (Pf)Trm14 were solved in complex with the methyl donor S-adenosyl-l-methionine (SAM or AdoMet), as well as the reaction product S-adenosyl-homocysteine (SAH or AdoHcy) and the inhibitor sinefungin. (TTC)TrmN and (Pf)Trm14 consist of an N-terminal THUMP domain fused to a catalytic Rossmann-fold MTase (RFM) domain. These results represent the first crystallographic structure analysis of proteins containing both THUMP and RFM domain, and hence provide further insight in the contribution of the THUMP domain in tRNA recognition and catalysis. Electrostatics and conservation calculations suggest a main tRNA binding surface in a groove between the THUMP domain and the MTase domain. This is further supported by a docking model of TrmN in complex with tRNA(Phe) of T. thermophilus and via site-directed mutagenesis.

-	~~==About this Structure==~~	+	Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life.,Fislage M, Roovers M, Tuszynska I, Bujnicki JM, Droogmans L, Versees W Nucleic Acids Res. 2012 Feb 22. PMID:22362751<ref>PMID:22362751</ref>
-	~~[[3tlj]] is a 2 chain structure with sequence from [http~~:/~~/en~~.~~wikipedia~~.~~org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3TLJ OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
		+	*[[TRNA methyltransferase\|TRNA methyltransferase]]
	*[[TRNA:m2G6 methyltransferase TrmN/Trm14\|TRNA:m2G6 methyltransferase TrmN/Trm14]]		*[[TRNA:m2G6 methyltransferase TrmN/Trm14\|TRNA:m2G6 methyltransferase TrmN/Trm14]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:022362751<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Pyrococcus furiosus]]		[[Category: Pyrococcus furiosus]]
-	[[Category: Bujnicki, J M.]]	+	[[Category: Bujnicki, J M]]
-	[[Category: Droogmans, L.]]	+	[[Category: Droogmans, L]]
-	[[Category: Fislage, M.]]	+	[[Category: Fislage, M]]
-	[[Category: Roovers, M.]]	+	[[Category: Roovers, M]]
-	[[Category: Tuszynska, I.]]	+	[[Category: Tuszynska, I]]
-	[[Category: Versees, W.]]	+	[[Category: Versees, W]]
	[[Category: Methyltransferase]]		[[Category: Methyltransferase]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]

OCA at 09:31, 11 March 2013

OCA — Mon, 11 Mar 2013 09:31:25 GMT

←Older revision		Revision as of 09:31, 11 March 2013
Line 1:		Line 1:
-	[[Image:3tlj.png\|left\|200px]]
-
	{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}		{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}
-
	===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===		===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===
-
	{{ABSTRACT_PUBMED_22362751}}		{{ABSTRACT_PUBMED_22362751}}

OCA at 06:33, 3 October 2012

OCA — Wed, 03 Oct 2012 06:33:21 GMT

←Older revision		Revision as of 06:33, 3 October 2012
Line 1:		Line 1:
	[[Image:3tlj.png\|left\|200px]]		[[Image:3tlj.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3tlj", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}		{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}

	===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===		===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_22362751}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 22362751 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_22362751}}		{{ABSTRACT_PUBMED_22362751}}

	==About this Structure==		==About this Structure==
	[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA].		[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA].
		+
		+	==See Also==
		+	*[[TRNA:m2G6 methyltransferase TrmN/Trm14\|TRNA:m2G6 methyltransferase TrmN/Trm14]]

	==Reference==		==Reference==

OCA at 06:51, 18 April 2012

OCA — Wed, 18 Apr 2012 06:51:21 GMT

←Older revision		Revision as of 06:51, 18 April 2012
Line 1:		Line 1:
-	[[Image:3tlj.~~jpg~~\|left\|200px]]	+	[[Image:3tlj.png\|left\|200px]]

	<!--		<!--

OCA at 06:30, 14 March 2012

OCA — Wed, 14 Mar 2012 06:30:04 GMT

←Older revision		Revision as of 06:30, 14 March 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tlj.jpg\|left\|200px]]

-	The ~~entry 3tlj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3tlj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3tlj\| PDB=3tlj \| SCENE= }}

-	~~Authors: Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans,~~ L~~., Versees, W.~~	+	===Crystal structure of Trm14 from Pyrococcus furiosus in complex with S-adenosyl-L-homocysteine===

-	~~Description~~:	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22362751}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22362751 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22362751}}
		+
		+	==About this Structure==
		+	[[3tlj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TLJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022362751</ref><references group="xtra"/>
		+	[[Category: Pyrococcus furiosus]]
		+	[[Category: Bujnicki, J M.]]
		+	[[Category: Droogmans, L.]]
		+	[[Category: Fislage, M.]]
		+	[[Category: Roovers, M.]]
		+	[[Category: Tuszynska, I.]]
		+	[[Category: Versees, W.]]
		+	[[Category: Methyltransferase]]
		+	[[Category: Rossmann fold]]
		+	[[Category: Thump domain]]
		+	[[Category: Transferase]]
		+	[[Category: Trna methyltransferase]]

OCA at 06:04, 14 September 2011

OCA — Wed, 14 Sep 2011 06:04:58 GMT

←Older revision		Revision as of 06:04, 14 September 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tlj is ON HOLD	+	The entry 3tlj is ON HOLD until Paper Publication

	Authors: Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.		Authors: Fislage, M., Roovers, M., Tuszynska, I., Bujnicki, J.M., Droogmans, L., Versees, W.

	Description:		Description:

OCA: Protected "3tlj" [edit=sysop:move=sysop]

OCA — Wed, 07 Sep 2011 05:49:57 GMT

Protected "3tlj" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:49, 7 September 2011