3tpv - Revision history

OCA at 17:08, 6 July 2022

OCA — Wed, 06 Jul 2022 17:08:14 GMT

←Older revision		Revision as of 17:08, 6 July 2022
Line 1:		Line 1:

	==Structure of pHipA bound to ADP==		==Structure of pHipA bound to ADP==
-	<StructureSection load='3tpv' size='340' side='right' caption='[[3tpv]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='3tpv' size='340' side='right'caption='[[3tpv]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tpv]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3TPV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tpv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TPV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnt\|3dnt]], [[3dnu\|3dnu]], [[3dnv\|3dnv]], [[3fbr\|3fbr]], [[3hzi\|3hzi]], [[3tpb\|3tpb]], [[3tpd\|3tpd]], [[3tpe\|3tpe]], [[3tpt\|3tpt]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3dnt\|3dnt]], [[3dnu\|3dnu]], [[3dnv\|3dnv]], [[3fbr\|3fbr]], [[3hzi\|3hzi]], [[3tpb\|3tpb]], [[3tpd\|3tpd]], [[3tpe\|3tpe]], [[3tpt\|3tpt]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hipA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hipA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [~~http~~://pdbe.org/3tpv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3tpv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [https://pdbe.org/3tpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [https://www.ebi.ac.uk/pdbsum/3tpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HIPA_ECOLI HIPA_ECOLI]] Toxic component of a toxin-antitoxin (TA) module. Autophosphorylates (Ser-150) and phosphorylates EF-Tu in vitro (on 'Thr-383'), may act on other proteins as well. The hipA7 mutation leads to increased generation of persister cells, cells that survive antibiotic treatment probably by entering into a dormant state. Wild-type cells produce persisters at a frequency of 10-6 to 10-5 whereas mutant hipA7 cells produce persisters at a frequency of 10-2. Generation of persister cells requires (p)ppGpp as cells lacking relA or relA/spoT generate fewer or no persister cells respectively compared to hipA7. Low level expression of HipA causes cell filamentation and depending on the protein level is toxic enough to reduce cell growth or even kill cells. Expression of wild-type HipA also leads to high antibiotic tolerance of the survivor cells. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. With HipB acts as a corepressor for transcription of the hipBA promoter.<ref>PMID:17041039</ref> <ref>PMID:6348026</ref> <ref>PMID:8021189</ref> <ref>PMID:14622409</ref> <ref>PMID:19150849</ref>	+	[[https://www.uniprot.org/uniprot/HIPA_ECOLI HIPA_ECOLI]] Toxic component of a toxin-antitoxin (TA) module. Autophosphorylates (Ser-150) and phosphorylates EF-Tu in vitro (on 'Thr-383'), may act on other proteins as well. The hipA7 mutation leads to increased generation of persister cells, cells that survive antibiotic treatment probably by entering into a dormant state. Wild-type cells produce persisters at a frequency of 10-6 to 10-5 whereas mutant hipA7 cells produce persisters at a frequency of 10-2. Generation of persister cells requires (p)ppGpp as cells lacking relA or relA/spoT generate fewer or no persister cells respectively compared to hipA7. Low level expression of HipA causes cell filamentation and depending on the protein level is toxic enough to reduce cell growth or even kill cells. Expression of wild-type HipA also leads to high antibiotic tolerance of the survivor cells. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. With HipB acts as a corepressor for transcription of the hipBA promoter.<ref>PMID:17041039</ref> <ref>PMID:6348026</ref> <ref>PMID:8021189</ref> <ref>PMID:14622409</ref> <ref>PMID:19150849</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 24:

	==See Also==		==See Also==
-	*[[Serine/threonine protein kinase\|Serine/threonine protein kinase]]	+	*[[Serine/threonine protein kinase 3D structures\|Serine/threonine protein kinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Brennan, R G]]		[[Category: Brennan, R G]]

OCA at 08:05, 4 August 2016

OCA — Thu, 04 Aug 2016 08:05:31 GMT

←Older revision		Revision as of 08:05, 4 August 2016
Line 1:		Line 1:
		+
	==Structure of pHipA bound to ADP==		==Structure of pHipA bound to ADP==
	<StructureSection load='3tpv' size='340' side='right' caption='[[3tpv]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='3tpv' size='340' side='right' caption='[[3tpv]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3tpv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TPV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3tpv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TPV FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnt\|3dnt]], [[3dnu\|3dnu]], [[3dnv\|3dnv]], [[3fbr\|3fbr]], [[3hzi\|3hzi]], [[3tpb\|3tpb]], [[3tpd\|3tpd]], [[3tpe\|3tpe]], [[3tpt\|3tpt]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnt\|3dnt]], [[3dnu\|3dnu]], [[3dnv\|3dnv]], [[3fbr\|3fbr]], [[3hzi\|3hzi]], [[3tpb\|3tpb]], [[3tpd\|3tpd]], [[3tpe\|3tpe]], [[3tpt\|3tpt]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hipA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hipA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [http://www.ebi.ac.uk/pdbsum/3tpv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [http://pdbe.org/3tpv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [http://www.ebi.ac.uk/pdbsum/3tpv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3tpv ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 20:		Line 21:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3tpv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 27:		Line 29:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
	[[Category: Brennan, R G]]		[[Category: Brennan, R G]]

OCA at 07:23, 24 December 2014

OCA — Wed, 24 Dec 2014 07:23:41 GMT

←Older revision		Revision as of 07:23, 24 December 2014
Line 10:		Line 10:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [http://www.ebi.ac.uk/pdbsum/3tpv PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [http://www.ebi.ac.uk/pdbsum/3tpv PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HIPA_ECOLI HIPA_ECOLI]] Toxic component of a toxin-antitoxin (TA) module. Autophosphorylates (Ser-150) and phosphorylates EF-Tu in vitro (on 'Thr-383'), may act on other proteins as well. The hipA7 mutation leads to increased generation of persister cells, cells that survive antibiotic treatment probably by entering into a dormant state. Wild-type cells produce persisters at a frequency of 10-6 to 10-5 whereas mutant hipA7 cells produce persisters at a frequency of 10-2. Generation of persister cells requires (p)ppGpp as cells lacking relA or relA/spoT generate fewer or no persister cells respectively compared to hipA7. Low level expression of HipA causes cell filamentation and depending on the protein level is toxic enough to reduce cell growth or even kill cells. Expression of wild-type HipA also leads to high antibiotic tolerance of the survivor cells. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. With HipB acts as a corepressor for transcription of the hipBA promoter.<ref>PMID:17041039</ref> <ref>PMID:6348026</ref> <ref>PMID:8021189</ref> <ref>PMID:14622409</ref> <ref>PMID:19150849</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 15:50, 9 December 2014

OCA — Tue, 09 Dec 2014 15:50:48 GMT

←Older revision		Revision as of 15:50, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3tpv.~~png~~\|~~left~~\|~~200px~~]]	+	==Structure of pHipA bound to ADP==
		+	<StructureSection load='3tpv' size='340' side='right' caption='[[3tpv]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3tpv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TPV FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3dnt\|3dnt]], [[3dnu\|3dnu]], [[3dnv\|3dnv]], [[3fbr\|3fbr]], [[3hzi\|3hzi]], [[3tpb\|3tpb]], [[3tpd\|3tpd]], [[3tpe\|3tpe]], [[3tpt\|3tpt]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hipA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tpv OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tpv RCSB], [http://www.ebi.ac.uk/pdbsum/3tpv PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	HipA is a bacterial serine/threonine protein kinase that phosphorylates targets, bringing about persistence and multidrug tolerance. Autophosphorylation of residue Ser150 is a critical regulatory mechanism of HipA function. Intriguingly, Ser150 is not located on the activation loop, as are other kinases; instead, it is in the protein core, where it forms part of the ATP-binding "P loop motif." How this buried residue is phosphorylated and regulates kinase activity is unclear. Here, we report multiple structures that reveal the P loop motif's exhibition of a remarkable "in-out" conformational equilibrium, which allows access to Ser150 and its intermolecular autophosphorylation. Phosphorylated Ser150 stabilizes the "out state," which inactivates the kinase by disrupting the ATP-binding pocket. Thus, our data reveal a mechanism of protein kinase regulation that is vital for multidrug tolerance and persistence, as kinase inactivation provides the critical first step in allowing dormant cells to revert to the growth phenotype and to reinfect the host.

-	~~{{STRUCTURE_3tpv\| PDB=3tpv \| SCENE= }}~~	+	Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance.,Schumacher MA, Min J, Link TM, Guan Z, Xu W, Ahn YH, Soderblom EJ, Kurie JM, Evdokimov A, Moseley MA, Lewis K, Brennan RG Cell Rep. 2012 Sep 27;2(3):518-25. doi: 10.1016/j.celrep.2012.08.013. Epub 2012, Sep 20. PMID:22999936<ref>PMID:22999936</ref>

-	~~===Structure~~ of ~~pHipA bound to ADP===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22999936}}~~	+	==See Also==
-		+	*[[Serine/threonine protein kinase\|Serine/threonine protein kinase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~3tpv]] is a 1 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Escherichia_coli Escherichia coli~~]~~. Full crystallographic information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA].~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Non-specific serine/threonine protein kinase]]		[[Category: Non-specific serine/threonine protein kinase]]
-	[[Category: Brennan, R G.]]	+	[[Category: Brennan, R G]]
-	[[Category: Link, T M.]]	+	[[Category: Link, T M]]
-	[[Category: Schumacher, M A.]]	+	[[Category: Schumacher, M A]]
	[[Category: Hipa]]		[[Category: Hipa]]
	[[Category: Hipb]]		[[Category: Hipb]]

OCA at 06:11, 17 October 2012

OCA — Wed, 17 Oct 2012 06:11:20 GMT

←Older revision		Revision as of 06:11, 17 October 2012
Line 1:		Line 1:
-	[[Image:3tpv.~~jpg~~\|left\|200px]]	+	[[Image:3tpv.png\|left\|200px]]

	{{STRUCTURE_3tpv\| PDB=3tpv \| SCENE= }}		{{STRUCTURE_3tpv\| PDB=3tpv \| SCENE= }}

OCA at 06:15, 3 October 2012

OCA — Wed, 03 Oct 2012 06:15:53 GMT

←Older revision		Revision as of 06:15, 3 October 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3tpv.jpg\|left\|200px]]

-	~~The entry~~ 3tpv ~~is ON HOLD~~ ~~until Oct 26 2013~~	+	{{STRUCTURE_3tpv\| PDB=3tpv \| SCENE= }}

-	~~Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.~~	+	===Structure of pHipA bound to ADP===

-	~~Description:~~ Structure ~~of pHipA bound to ADP~~	+	{{ABSTRACT_PUBMED_22999936}}
		+
		+	==About this Structure==
		+	[[3tpv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TPV OCA].
		+	[[Category: Escherichia coli]]
		+	[[Category: Non-specific serine/threonine protein kinase]]
		+	[[Category: Brennan, R G.]]
		+	[[Category: Link, T M.]]
		+	[[Category: Schumacher, M A.]]
		+	[[Category: Hipa]]
		+	[[Category: Hipb]]
		+	[[Category: Multidrug tolerance]]
		+	[[Category: Persistence]]
		+	[[Category: Transferase]]

OCA at 19:52, 26 September 2012

OCA — Wed, 26 Sep 2012 19:52:45 GMT

←Older revision		Revision as of 19:52, 26 September 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tpv is ON HOLD until ~~Sep~~ 26 2013	+	The entry 3tpv is ON HOLD until Oct 26 2013

	Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.		Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.

	Description: Structure of pHipA bound to ADP		Description: Structure of pHipA bound to ADP

OCA at 04:38, 5 September 2012

OCA — Wed, 05 Sep 2012 04:38:25 GMT

←Older revision		Revision as of 04:38, 5 September 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tpv is ON HOLD until ~~Paper Publication~~	+	The entry 3tpv is ON HOLD until Sep 26 2013

	Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.		Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.

	Description: Structure of pHipA bound to ADP		Description: Structure of pHipA bound to ADP

OCA at 05:16, 22 August 2012

OCA — Wed, 22 Aug 2012 05:16:35 GMT

←Older revision		Revision as of 05:16, 22 August 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tpv is ON HOLD until ~~Sep 02 2013~~	+	The entry 3tpv is ON HOLD until Paper Publication

	Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.		Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.

	Description: Structure of pHipA bound to ADP		Description: Structure of pHipA bound to ADP

OCA at 06:33, 25 July 2012

OCA — Wed, 25 Jul 2012 06:33:01 GMT

←Older revision		Revision as of 06:33, 25 July 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3tpv is ON HOLD until ~~Paper Publication~~	+	The entry 3tpv is ON HOLD until Sep 02 2013

	Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.		Authors: Schumacher, M.A., Link, T.M., Brennan, R.G.

	Description: Structure of pHipA bound to ADP		Description: Structure of pHipA bound to ADP