3u1y - Revision history

OCA at 13:45, 14 March 2024

OCA — Thu, 14 Mar 2024 13:45:49 GMT

←Older revision		Revision as of 13:45, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3u1y' size='340' side='right'caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3u1y' size='340' side='right'caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [https://pdbe.org/3u1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [https://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [https://pdbe.org/3u1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [https://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	+	[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	In this paper we present the synthesis and SAR as well as selectivity, pharmacokinetic and infection model data for representative analogs of a novel series of potent antibacterial LpxC inhibitors represented by hydroxamic acid 1a.	+
-		+
-	Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections.,Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels J, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mulllins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello D, Warmus J, Wishka DG J Med Chem. 2011 Dec 18. PMID:22175825<ref>PMID:22175825</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3u1y" style="background-color:#fffaf0;"></div>~~	+

	==See Also==		==See Also==
	*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase\|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]		*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase\|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
-	~~== References ==~~	+	*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures\|UDP-3-O-acyl-N-acetylglucosamine deacetylase 3D structures]]
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Abramite, J]]
-	[[Category: Brown, M]]
-	[[Category: Liu, S]]
-	[[Category: Gram negative]]
-	[[Category: Hydrolase-hydrolase inhibitor complex]]
-	[[Category: Lpxc]]
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
		+	[[Category: Abramite J]]
		+	[[Category: Brown M]]
		+	[[Category: Liu S]]

OCA at 05:54, 13 July 2022

OCA — Wed, 13 Jul 2022 05:54:23 GMT

←Older revision		Revision as of 05:54, 13 July 2022
Line 1:		Line 1:

	==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==		==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==
-	<StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='3u1y' size='340' side='right'caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [~~http~~://pdbe.org/3u1y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [https://pdbe.org/3u1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [https://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	+	[[https://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Abramite, J]]		[[Category: Abramite, J]]
	[[Category: Brown, M]]		[[Category: Brown, M]]

OCA at 18:37, 4 August 2016

OCA — Thu, 04 Aug 2016 18:37:04 GMT

←Older revision		Revision as of 18:37, 4 August 2016
Line 1:		Line 1:
		+
	==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==		==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==
	<StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_aeruginosa Pseudomonas aeruginosa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_aeruginosus"_(schroeter_1872)_trevisan_1885 "bacillus aeruginosus" (schroeter 1872) trevisan 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 ~~Pseudomonas aeruginosa~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 "Bacillus aeruginosus" (Schroeter 1872) Trevisan 1885])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://pdbe.org/3u1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u1y ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3u1y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pseudomonas aeruginosa]]
	[[Category: Abramite, J]]		[[Category: Abramite, J]]
	[[Category: Brown, M]]		[[Category: Brown, M]]
Line 31:		Line 32:
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Lpxc]]		[[Category: Lpxc]]
		+	[[Category: Pseudomonas aeruginosa]]

OCA at 11:58, 25 December 2014

OCA — Thu, 25 Dec 2014 11:58:44 GMT

←Older revision		Revision as of 11:58, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LPXC_PSEAE LPXC_PSEAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 17:20, 9 December 2014

OCA — Tue, 09 Dec 2014 17:20:21 GMT

←Older revision		Revision as of 17:20, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3u1y.~~png~~\|~~left~~\|~~200px~~]]	+	==Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections==
		+	<StructureSection load='3u1y' size='340' side='right' caption='[[3u1y]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U1Y FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=03I:(2R)-N-HYDROXY-2-METHYL-2-(METHYLSULFONYL)-4-{4-[3-(MORPHOLIN-4-YL)PROPOXY]BIPHENYL-4-YL}BUTANAMIDE'>03I</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lpxC, envA, PA4406 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=287 Pseudomonas aeruginosa])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u1y RCSB], [http://www.ebi.ac.uk/pdbsum/3u1y PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In this paper we present the synthesis and SAR as well as selectivity, pharmacokinetic and infection model data for representative analogs of a novel series of potent antibacterial LpxC inhibitors represented by hydroxamic acid 1a.

-	~~{{STRUCTURE_3u1y\| PDB=3u1y \| SCENE= }}~~	+	Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections.,Brown MF, Reilly U, Abramite JA, Arcari JT, Oliver R, Barham RA, Che Y, Chen JM, Collantes EM, Chung SW, Desbonnet C, Doty J, Doroski M, Engtrakul JJ, Harris TM, Huband M, Knafels J, Leach KL, Liu S, Marfat A, Marra A, McElroy E, Melnick M, Menard CA, Montgomery JI, Mulllins L, Noe MC, O'Donnell J, Penzien J, Plummer MS, Price LM, Shanmugasundaram V, Thoma C, Uccello D, Warmus J, Wishka DG J Med Chem. 2011 Dec 18. PMID:22175825<ref>PMID:22175825</ref>

-	~~===Potent Inhibitors~~ of ~~LpxC for~~ the ~~Treatment~~ of ~~Gram-Negative Infections===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_22175825}}~~	+	==See Also==
-		+	*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase\|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~3u1y~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:022175825<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pseudomonas aeruginosa]]		[[Category: Pseudomonas aeruginosa]]
-	[[Category: Abramite, J.]]	+	[[Category: Abramite, J]]
-	[[Category: Brown, M.]]	+	[[Category: Brown, M]]
-	[[Category: Liu, S.]]	+	[[Category: Liu, S]]
	[[Category: Gram negative]]		[[Category: Gram negative]]
	[[Category: Hydrolase-hydrolase inhibitor complex]]		[[Category: Hydrolase-hydrolase inhibitor complex]]
	[[Category: Lpxc]]		[[Category: Lpxc]]
-	[[Category: Pseudomonas aeruginosa]]

OCA at 07:20, 2 January 2013

OCA — Wed, 02 Jan 2013 07:20:02 GMT

←Older revision		Revision as of 07:20, 2 January 2013
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-	[[Image:3u1y.~~jpg~~\|left\|200px]]	+	[[Image:3u1y.png\|left\|200px]]

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	{{STRUCTURE_3u1y\| PDB=3u1y \| SCENE= }}		{{STRUCTURE_3u1y\| PDB=3u1y \| SCENE= }}

	===Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections===		===Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections===

-
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	{{ABSTRACT_PUBMED_22175825}}		{{ABSTRACT_PUBMED_22175825}}

OCA at 06:06, 4 January 2012

OCA — Wed, 04 Jan 2012 06:06:17 GMT

←Older revision		Revision as of 06:06, 4 January 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3u1y.jpg\|left\|200px]]

-	The ~~entry 3u1y~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3u1y", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3u1y\| PDB=3u1y \| SCENE= }}

-	~~Authors: Brown, M., Abramite, J., Liu, S.~~	+	===Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections===

-	~~Description~~: ~~Potent Inhibitors of LpxC for~~ the ~~Treatment of~~ Gram-~~Negative Infections~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22175825}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22175825 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22175825}}
		+
		+	==About this Structure==
		+	[[3u1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U1Y OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022175825</ref><references group="xtra"/>
		+	[[Category: Pseudomonas aeruginosa]]
		+	[[Category: Abramite, J.]]
		+	[[Category: Brown, M.]]
		+	[[Category: Liu, S.]]
		+	[[Category: Gram negative]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Lpxc]]
		+	[[Category: Pseudomonas aeruginosa]]

OCA at 11:49, 16 November 2011

OCA — Wed, 16 Nov 2011 11:49:05 GMT

←Older revision		Revision as of 11:49, 16 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3u1y is ON HOLD	+	The entry 3u1y is ON HOLD until Paper Publication

	Authors: Brown, M., Abramite, J., Liu, S.		Authors: Brown, M., Abramite, J., Liu, S.

	Description: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections		Description: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

OCA: Protected "3u1y" [edit=sysop:move=sysop]

OCA — Sun, 30 Oct 2011 08:48:07 GMT

Protected "3u1y" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:48, 30 October 2011

OCA: New page: '''Unreleased structure''' The entry 3u1y is ON HOLD Authors: Brown, M., Abramite, J., Liu, S. Description: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

OCA — Sun, 30 Oct 2011 08:48:06 GMT

New page: '''Unreleased structure''' The entry 3u1y is ON HOLD Authors: Brown, M., Abramite, J., Liu, S. Description: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections

New page

'''Unreleased structure'''

The entry 3u1y is ON HOLD

Authors: Brown, M., Abramite, J., Liu, S.

Description: Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections