3u7b - Revision history

OCA at 13:49, 14 March 2024

OCA — Thu, 14 Mar 2024 13:49:46 GMT

←Older revision		Revision as of 13:49, 14 March 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U7B FirstGlance]. <br>		<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U7B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.94Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [https://pdbe.org/3u7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [https://www.ebi.ac.uk/pdbsum/3u7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7b ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [https://pdbe.org/3u7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [https://www.ebi.ac.uk/pdbsum/3u7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7b ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/XYNA_FUSO4 XYNA_FUSO4] Catalyzes the hydrolysis of the internal glycosidic bonds in heteroxylans, releasing mainly xylobiose and xylotriose. Most active on oat-spelt xylan.<ref>PMID:9291571</ref>
-	Xylanase enzymes have been the focus of considerable research in recent decades owing to their extensive use in a variety of biotechnological applications. Previous structural studies of a number of GH10 xylanases revealed that all GH10 family members have the (beta/~~alpha)(8)-barrel fold and their catalytic site is conserved~~. ~~The structure of a new GH10 xylanase from Fusarium oxysporum (FoXyn10a) was determined at 1~~.~~94 A resolution from crystals belonging to~~ the ~~tetragonal space group P4(1)2(1)2 with five molecules per asymmetric unit. Comparison~~ of the ~~structure of FoXyn10a with previously determined structures of GH10 family members indicated that most of the differences were located~~ in ~~the loop regions between the ordered secondary-structure elements of the barrel~~, ~~as expected. However, alignment of FoXyn10a with sequence~~ and ~~structural homologues denoted an atypically long loop connecting strand beta6b and helix alpha6 that was only present in one other GH10 xylanase, the structure of which is not known~~. ~~This structural feature may be of functional importance, with potential implications in the catalytic efficiency of the enzyme.~~	+
-		+
-	~~The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop~~ on ~~top of the catalytic cleft.,Dimarogona M, Topakas E, Christakopoulos P, Chrysina ED Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):735~~-42. ~~Epub 2012 Jun 15. PMID:22751658~~<ref>PMID:~~22751658~~</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3u7b" style="background-color:#fffaf0;"></div~~>	+
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Christakopoulos, P]]	+	[[Category: Christakopoulos P]]
-	[[Category: Chrysina~~, E D~~]]	+	[[Category: Chrysina ED]]
-	[[Category: Dimarogona, M]]	+	[[Category: Dimarogona M]]
-	[[Category: Topakas, E]]	+	[[Category: Topakas E]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Tim barrel]]~~	+
-	~~[[Category: Xylanase~~]]	+

OCA at 06:01, 13 July 2022

OCA — Wed, 13 Jul 2022 06:01:01 GMT

←Older revision		Revision as of 06:01, 13 July 2022
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	==A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft==		==A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft==
-	<StructureSection load='3u7b' size='340' side='right' caption='[[3u7b]], [[Resolution\|resolution]] 1.94Å' scene=''>	+	<StructureSection load='3u7b' size='340' side='right'caption='[[3u7b]], [[Resolution\|resolution]] 1.94Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3U7B FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U7B FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [~~http~~://pdbe.org/3u7b PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3u7b PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7b ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [https://pdbe.org/3u7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [https://www.ebi.ac.uk/pdbsum/3u7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7b ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
		+	[[Category: Large Structures]]
	[[Category: Christakopoulos, P]]		[[Category: Christakopoulos, P]]
	[[Category: Chrysina, E D]]		[[Category: Chrysina, E D]]

OCA at 09:38, 11 August 2016

OCA — Thu, 11 Aug 2016 09:38:06 GMT

←Older revision		Revision as of 09:38, 11 August 2016
Line 1:		Line 1:
		+
	==A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft==		==A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft==
	<StructureSection load='3u7b' size='340' side='right' caption='[[3u7b]], [[Resolution\|resolution]] 1.94Å' scene=''>		<StructureSection load='3u7b' size='340' side='right' caption='[[3u7b]], [[Resolution\|resolution]] 1.94Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [http://www.ebi.ac.uk/pdbsum/3u7b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [http://pdbe.org/3u7b PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [http://www.ebi.ac.uk/pdbsum/3u7b PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3u7b ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3u7b" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:59, 4 January 2015

OCA — Sun, 04 Jan 2015 09:59:18 GMT

←Older revision		Revision as of 09:59, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7B FirstGlance]. <br>		<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7B FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [http://www.ebi.ac.uk/pdbsum/3u7b PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [http://www.ebi.ac.uk/pdbsum/3u7b PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 13:
	The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft.,Dimarogona M, Topakas E, Christakopoulos P, Chrysina ED Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):735-42. Epub 2012 Jun 15. PMID:22751658<ref>PMID:22751658</ref>		The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft.,Dimarogona M, Topakas E, Christakopoulos P, Chrysina ED Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):735-42. Epub 2012 Jun 15. PMID:22751658<ref>PMID:22751658</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 21:		Line 21:
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
-	[[Category: Christakopoulos, P.]]	+	[[Category: Christakopoulos, P]]
-	[[Category: Chrysina, E D.]]	+	[[Category: Chrysina, E D]]
-	[[Category: Dimarogona, M.]]	+	[[Category: Dimarogona, M]]
-	[[Category: Topakas, E.]]	+	[[Category: Topakas, E]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Tim barrel]]		[[Category: Tim barrel]]
	[[Category: Xylanase]]		[[Category: Xylanase]]

OCA at 06:35, 5 June 2014

OCA — Thu, 05 Jun 2014 06:35:30 GMT

←Older revision		Revision as of 06:35, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3u7b.~~jpg~~\|~~left\|200px~~]]	+	==A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft==
		+	<StructureSection load='3u7b' size='340' side='right' caption='[[3u7b]], [[Resolution\|resolution]] 1.94Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3u7b]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U7B FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u7b RCSB], [http://www.ebi.ac.uk/pdbsum/3u7b PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Xylanase enzymes have been the focus of considerable research in recent decades owing to their extensive use in a variety of biotechnological applications. Previous structural studies of a number of GH10 xylanases revealed that all GH10 family members have the (beta/alpha)(8)-barrel fold and their catalytic site is conserved. The structure of a new GH10 xylanase from Fusarium oxysporum (FoXyn10a) was determined at 1.94 A resolution from crystals belonging to the tetragonal space group P4(1)2(1)2 with five molecules per asymmetric unit. Comparison of the structure of FoXyn10a with previously determined structures of GH10 family members indicated that most of the differences were located in the loop regions between the ordered secondary-structure elements of the barrel, as expected. However, alignment of FoXyn10a with sequence and structural homologues denoted an atypically long loop connecting strand beta6b and helix alpha6 that was only present in one other GH10 xylanase, the structure of which is not known. This structural feature may be of functional importance, with potential implications in the catalytic efficiency of the enzyme.

-	~~{{STRUCTURE_3u7b\| PDB=3u7b \| SCENE= }}~~	+	The structure of a GH10 xylanase from Fusarium oxysporum reveals the presence of an extended loop on top of the catalytic cleft.,Dimarogona M, Topakas E, Christakopoulos P, Chrysina ED Acta Crystallogr D Biol Crystallogr. 2012 Jul;68(Pt 7):735-42. Epub 2012 Jun 15. PMID:22751658<ref>PMID:22751658</ref>

-	~~===A new crystal structure of~~ a ~~Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top~~ of the ~~catalytic cleft===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22751658}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[3u7b]] is a 5 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Fusarium_oxysporum Fusarium oxysporum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022751658<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Endo-1,4-beta-xylanase]]		[[Category: Endo-1,4-beta-xylanase]]
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]

OCA at 05:21, 18 July 2012

OCA — Wed, 18 Jul 2012 05:21:17 GMT

←Older revision		Revision as of 05:21, 18 July 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3u7b.jpg\|left\|200px]]

-	~~The entry~~ 3u7b ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3u7b\| PDB=3u7b \| SCENE= }}

-	~~Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.~~	+	===A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft===

-	~~Description: A new crystal structure of~~ a Fusarium oxysporum ~~GH10~~ xylanase ~~reveals the presence of an extended loop on top of the catalytic cleft~~	+	{{ABSTRACT_PUBMED_22751658}}
		+
		+	==About this Structure==
		+	[[3u7b]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U7B OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022751658</ref><references group="xtra"/>
		+	[[Category: Endo-1,4-beta-xylanase]]
		+	[[Category: Fusarium oxysporum]]
		+	[[Category: Christakopoulos, P.]]
		+	[[Category: Chrysina, E D.]]
		+	[[Category: Dimarogona, M.]]
		+	[[Category: Topakas, E.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Tim barrel]]
		+	[[Category: Xylanase]]

OCA at 18:34, 23 November 2011

OCA — Wed, 23 Nov 2011 18:34:24 GMT

←Older revision		Revision as of 18:34, 23 November 2011
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3u7b is ON HOLD	+	The entry 3u7b is ON HOLD until Paper Publication

	Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.		Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.

	Description: A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft		Description: A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft

OCA at 11:14, 9 November 2011

OCA — Wed, 09 Nov 2011 11:14:39 GMT

←Older revision		Revision as of 11:14, 9 November 2011
Line 3:		Line 3:
	The entry 3u7b is ON HOLD		The entry 3u7b is ON HOLD

-	Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E. D.	+	Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E.D.

-	Description: A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft.	+	Description: A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft

OCA: Protected "3u7b" [edit=sysop:move=sysop]

OCA — Sun, 30 Oct 2011 08:53:44 GMT

Protected "3u7b" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:53, 30 October 2011

OCA: New page: '''Unreleased structure''' The entry 3u7b is ON HOLD Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E. D. Description: A new crystal structure of a Fusarium oxysp...

OCA — Sun, 30 Oct 2011 08:53:43 GMT

New page: '''Unreleased structure''' The entry 3u7b is ON HOLD Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E. D. Description: A new crystal structure of a Fusarium oxysp...

New page

'''Unreleased structure'''

The entry 3u7b is ON HOLD

Authors: Dimarogona, M., Topakas, E., Christakopoulos, P., Chrysina, E. D.

Description: A new crystal structure of a Fusarium oxysporum GH10 xylanase reveals the presence of an extended loop on top of the catalytic cleft.