3ue6 - Revision history

OCA at 10:21, 1 March 2024

OCA — Fri, 01 Mar 2024 10:21:31 GMT

←Older revision		Revision as of 10:21, 1 March 2024
Line 3:		Line 3:
	<StructureSection load='3ue6' size='340' side='right'caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='3ue6' size='340' side='right'caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Conferva_frigida Conferva~~ frigida]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>~~, ~~<scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.75Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~AUREO1 ([https~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=195983 Conferva frigida])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [https://pdbe.org/3ue6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [https://pdbe.org/3ue6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/A8QW55_VAUFR A8QW55_VAUFR]
-	Aureochrome1, a signaling photoreceptor from a eukaryotic photosynthetic stramenopile, confers blue-light-regulated DNA binding on the organism. Its topology, in which a C-terminal LOV sensor domain is linked to an N-terminal DNA-binding bZIP effector domain, contrasts with the reverse sensor-effector topology in most other known LOV-photoreceptors. How, then, is signal transmitted in Aureochrome1? The dark- and light-state crystal structures of Aureochrome1 LOV domain (AuLOV) show that its helical N- and C-terminal flanking regions are packed against the external surface of the core beta sheet, opposite to the FMN chromophore on the internal surface. Light-induced conformational changes occur in the quaternary structure of the AuLOV dimer and in Phe298 of the Hbeta strand in the core. The properties of AuLOV extend the applicability of LOV domains as versatile design modules that permit fusion to effector domains via either the N- or C-termini to confer blue-light sensitivity.	+
-		+
-	~~Crystal structures of Aureochrome1 LOV suggest new design strategies for optogenetics.,Mitra D, Yang X, Moffat K Structure. 2012 Apr 4;20(4)~~:~~698-706. doi: 10.1016~~/~~j.str.2012.02.016. Epub 2012, Apr 3. PMID:22483116<ref>PMID:22483116<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3ue6" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Conferva frigida]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Phototropin]]		[[Category: Phototropin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
-	[[Category: ~~Mitra, D~~]]	+	[[Category: Vaucheria frigida]]
-	[[Category: ~~Moffat, K~~]]	+	[[Category: Mitra D]]
-	[[Category: ~~Yang, X~~]]	+	[[Category: Moffat K]]
-	[[Category: ~~Fmn-binding blue-light photoreceptor]]~~	+	[[Category: Yang X]]
-	~~[[Category: Pas/lov domain]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 06:09, 13 July 2022

OCA — Wed, 13 Jul 2022 06:09:34 GMT

←Older revision		Revision as of 06:09, 13 July 2022
Line 3:		Line 3:
	<StructureSection load='3ue6' size='340' side='right'caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='3ue6' size='340' side='right'caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Conferva_frigida Conferva frigida]. The March 2015 RCSB PDB [~~http~~://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [~~http~~://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Conferva_frigida Conferva frigida]. The March 2015 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Conferva frigida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Conferva frigida])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [~~http~~://pdbe.org/3ue6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [https://pdbe.org/3ue6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:43, 17 July 2019

OCA — Wed, 17 Jul 2019 11:43:18 GMT

←Older revision		Revision as of 11:43, 17 July 2019
Line 1:		Line 1:

	==The dark structure of the blue-light photoreceptor Aureochrome1 LOV==		==The dark structure of the blue-light photoreceptor Aureochrome1 LOV==
-	<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>	+	<StructureSection load='3ue6' size='340' side='right'caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Conferva_frigida Conferva frigida]. The March 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Conferva_frigida Conferva frigida]. The March 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Conferva frigida]]		[[Category: Conferva frigida]]
		+	[[Category: Large Structures]]
	[[Category: Phototropin]]		[[Category: Phototropin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]

OCA at 10:03, 8 November 2017

OCA — Wed, 08 Nov 2017 10:03:17 GMT

←Older revision		Revision as of 10:03, 8 November 2017
Line 3:		Line 3:
	<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Vaucheria_frigida Vaucheria~~ frigida]. The March 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Conferva_frigida Conferva frigida]. The March 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 ~~Vaucheria~~ frigida])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Conferva frigida])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [http://pdbe.org/3ue6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [http://pdbe.org/3ue6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Conferva frigida]]
	[[Category: Phototropin]]		[[Category: Phototropin]]
	[[Category: RCSB PDB Molecule of the Month]]		[[Category: RCSB PDB Molecule of the Month]]
-	[[Category: Vaucheria frigida]]
	[[Category: Mitra, D]]		[[Category: Mitra, D]]
	[[Category: Moffat, K]]		[[Category: Moffat, K]]

OCA at 18:55, 10 December 2016

OCA — Sat, 10 Dec 2016 18:55:21 GMT

←Older revision		Revision as of 18:55, 10 December 2016
Line 1:		Line 1:
		+
	==The dark structure of the blue-light photoreceptor Aureochrome1 LOV==		==The dark structure of the blue-light photoreceptor Aureochrome1 LOV==
	<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>		<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. The March 2015 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Phototropin'' by David Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2015_3 10.2210/rcsb_pdb/mom_2015_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Vaucheria frigida])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Vaucheria frigida])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ue6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [http://pdbe.org/3ue6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ue6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ue6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3ue6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Phototropin]]
		+	[[Category: RCSB PDB Molecule of the Month]]
	[[Category: Vaucheria frigida]]		[[Category: Vaucheria frigida]]
	[[Category: Mitra, D]]		[[Category: Mitra, D]]

OCA at 16:26, 9 December 2014

OCA — Tue, 09 Dec 2014 16:26:00 GMT

←Older revision		Revision as of 16:26, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3ue6.~~png~~\|~~left~~\|~~200px~~]]	+	==The dark structure of the blue-light photoreceptor Aureochrome1 LOV==
		+	<StructureSection load='3ue6' size='340' side='right' caption='[[3ue6]], [[Resolution\|resolution]] 2.75Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UE6 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">AUREO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195983 Vaucheria frigida])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ue6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ue6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ue6 RCSB], [http://www.ebi.ac.uk/pdbsum/3ue6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Aureochrome1, a signaling photoreceptor from a eukaryotic photosynthetic stramenopile, confers blue-light-regulated DNA binding on the organism. Its topology, in which a C-terminal LOV sensor domain is linked to an N-terminal DNA-binding bZIP effector domain, contrasts with the reverse sensor-effector topology in most other known LOV-photoreceptors. How, then, is signal transmitted in Aureochrome1? The dark- and light-state crystal structures of Aureochrome1 LOV domain (AuLOV) show that its helical N- and C-terminal flanking regions are packed against the external surface of the core beta sheet, opposite to the FMN chromophore on the internal surface. Light-induced conformational changes occur in the quaternary structure of the AuLOV dimer and in Phe298 of the Hbeta strand in the core. The properties of AuLOV extend the applicability of LOV domains as versatile design modules that permit fusion to effector domains via either the N- or C-termini to confer blue-light sensitivity.

-	~~{{STRUCTURE_3ue6\| PDB=3ue6 \| SCENE= }}~~	+	Crystal structures of Aureochrome1 LOV suggest new design strategies for optogenetics.,Mitra D, Yang X, Moffat K Structure. 2012 Apr 4;20(4):698-706. doi: 10.1016/j.str.2012.02.016. Epub 2012, Apr 3. PMID:22483116<ref>PMID:22483116</ref>

-	~~===The dark structure~~ of the ~~blue-light photoreceptor Aureochrome1 LOV===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_22483116}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3ue6]] is a 6 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA].~~	+	</StructureSection>
	[[Category: Vaucheria frigida]]		[[Category: Vaucheria frigida]]
-	[[Category: Mitra, D.]]	+	[[Category: Mitra, D]]
-	[[Category: Moffat, K.]]	+	[[Category: Moffat, K]]
-	[[Category: Yang, X.]]	+	[[Category: Yang, X]]
	[[Category: Fmn-binding blue-light photoreceptor]]		[[Category: Fmn-binding blue-light photoreceptor]]
	[[Category: Pas/lov domain]]		[[Category: Pas/lov domain]]
	[[Category: Signaling protein]]		[[Category: Signaling protein]]

OCA at 12:37, 20 February 2013

OCA — Wed, 20 Feb 2013 12:37:26 GMT

←Older revision		Revision as of 12:37, 20 February 2013
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-	[[Image:3ue6.~~jpg~~\|left\|200px]]	+	[[Image:3ue6.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_3ue6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_3ue6\| PDB=3ue6 \| SCENE= }}		{{STRUCTURE_3ue6\| PDB=3ue6 \| SCENE= }}

	===The dark structure of the blue-light photoreceptor Aureochrome1 LOV===		===The dark structure of the blue-light photoreceptor Aureochrome1 LOV===

		+	{{ABSTRACT_PUBMED_22483116}}

	==About this Structure==		==About this Structure==

OCA at 07:09, 11 April 2012

OCA — Wed, 11 Apr 2012 07:09:28 GMT

←Older revision		Revision as of 07:09, 11 April 2012
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-	~~'''Unreleased structure'''~~	+	[[Image:3ue6.jpg\|left\|200px]]

-	The ~~entry 3ue6~~ is ~~ON HOLD~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3ue6", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3ue6\| PDB=3ue6 \| SCENE= }}

-	~~Authors: Mitra, D., Yang, X., Moffat, K.~~	+	===The dark structure of the blue-light photoreceptor Aureochrome1 LOV===

-	~~Description: The dark~~ structure ~~of the~~ blue-light photoreceptor ~~Aureochrome1 LOV~~	+
		+	==About this Structure==
		+	[[3ue6]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaucheria_frigida Vaucheria frigida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UE6 OCA].
		+	[[Category: Vaucheria frigida]]
		+	[[Category: Mitra, D.]]
		+	[[Category: Moffat, K.]]
		+	[[Category: Yang, X.]]
		+	[[Category: Fmn-binding blue-light photoreceptor]]
		+	[[Category: Pas/lov domain]]
		+	[[Category: Signaling protein]]

OCA: Protected "3ue6" [edit=sysop:move=sysop]

OCA — Wed, 09 Nov 2011 11:16:54 GMT

Protected "3ue6" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:16, 9 November 2011

OCA: New page: '''Unreleased structure''' The entry 3ue6 is ON HOLD Authors: Mitra, D., Yang, X., Moffat, K. Description: The dark structure of the blue-light photoreceptor Aureochrome1 LOV

OCA — Wed, 09 Nov 2011 11:16:53 GMT

New page: '''Unreleased structure''' The entry 3ue6 is ON HOLD Authors: Mitra, D., Yang, X., Moffat, K. Description: The dark structure of the blue-light photoreceptor Aureochrome1 LOV

New page

'''Unreleased structure'''

The entry 3ue6 is ON HOLD

Authors: Mitra, D., Yang, X., Moffat, K.

Description: The dark structure of the blue-light photoreceptor Aureochrome1 LOV