3v2k - Revision history

OCA at 12:16, 8 November 2023

OCA — Wed, 08 Nov 2023 12:16:13 GMT

←Older revision		Revision as of 12:16, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V2K FirstGlance]. <br>		<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V2K FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ADE:ADENINE'>ADE</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.07Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1aha\|1aha]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA~~ N-~~glycosylase], with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [https://pdbe.org/3v2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [https://www.ebi.ac.uk/pdbsum/3v2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2k ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [https://pdbe.org/3v2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [https://www.ebi.ac.uk/pdbsum/3v2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2k ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D9J2T9_MOMBA D9J2T9_MOMBA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 28:
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Momordica balsamina]]		[[Category: Momordica balsamina]]
-	~~[[Category: RRNA N-glycosylase]]~~	+	[[Category: Bhushan A]]
-	[[Category: Bhushan, A]]	+	[[Category: Kaur P]]
-	[[Category: Kaur, P]]	+	[[Category: Kushwaha GS]]
-	[[Category: Kushwaha~~, G S~~]]	+	[[Category: Pandey N]]
-	[[Category: Pandey, N]]	+	[[Category: Sharma S]]
-	[[Category: Sharma, S]]	+	[[Category: Singh TP]]
-	[[Category: Singh~~, T P~~]]	+	[[Category: Sinha M]]
-	[[Category: Sinha, M]]	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Inactivation]]~~	+
-	~~[[Category: Nitrogenous base]]~~	+
-	~~[[Category: Plant protein]]~~	+
-	~~[[Category: Ribose]]~~	+
-	~~[[Category: Rip]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Rna n-glycosidase~~]]	+

OCA at 08:25, 20 July 2022

OCA — Wed, 20 Jul 2022 08:25:10 GMT

←Older revision		Revision as of 08:25, 20 July 2022
Line 1:		Line 1:

	==Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution==		==Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution==
-	<StructureSection load='3v2k' size='340' side='right' caption='[[3v2k]], [[Resolution\|resolution]] 2.07Å' scene=''>	+	<StructureSection load='3v2k' size='340' side='right'caption='[[3v2k]], [[Resolution\|resolution]] 2.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3V2K FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V2K FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aha\|1aha]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [~~http~~://pdbe.org/3v2k PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3v2k PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2k ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [https://pdbe.org/3v2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [https://www.ebi.ac.uk/pdbsum/3v2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2k ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Ribosome inactivating protein\|Ribosome inactivating protein]]	+	*[[Ribosome inactivating protein 3D structures\|Ribosome inactivating protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Momordica balsamina]]		[[Category: Momordica balsamina]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 19:13, 11 August 2016

OCA — Thu, 11 Aug 2016 19:13:53 GMT

←Older revision		Revision as of 19:13, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution==		==Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution==
	<StructureSection load='3v2k' size='340' side='right' caption='[[3v2k]], [[Resolution\|resolution]] 2.07Å' scene=''>		<StructureSection load='3v2k' size='340' side='right' caption='[[3v2k]], [[Resolution\|resolution]] 2.07Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [http://www.ebi.ac.uk/pdbsum/3v2k PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [http://pdbe.org/3v2k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [http://www.ebi.ac.uk/pdbsum/3v2k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3v2k ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3v2k" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribosome inactivating protein\|Ribosome inactivating protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:50, 4 January 2015

OCA — Sun, 04 Jan 2015 10:50:06 GMT

←Older revision		Revision as of 10:50, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V2K FirstGlance]. <br>		<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V2K FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [http://www.ebi.ac.uk/pdbsum/3v2k PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [http://www.ebi.ac.uk/pdbsum/3v2k PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 14:		Line 14:
	Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.,Kushwaha GS, Pandey N, Sinha M, Singh SB, Kaur P, Sharma S, Singh TP Biochim Biophys Acta. 2012 Apr;1824(4):679-91. Epub 2012 Feb 14. PMID:22361570<ref>PMID:22361570</ref>		Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.,Kushwaha GS, Pandey N, Sinha M, Singh SB, Kaur P, Sharma S, Singh TP Biochim Biophys Acta. 2012 Apr;1824(4):679-91. Epub 2012 Feb 14. PMID:22361570<ref>PMID:22361570</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 22:		Line 22:
	[[Category: Momordica balsamina]]		[[Category: Momordica balsamina]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]
-	[[Category: Bhushan, A.]]	+	[[Category: Bhushan, A]]
-	[[Category: Kaur, P.]]	+	[[Category: Kaur, P]]
-	[[Category: Kushwaha, G S.]]	+	[[Category: Kushwaha, G S]]
-	[[Category: Pandey, N.]]	+	[[Category: Pandey, N]]
-	[[Category: Sharma, S.]]	+	[[Category: Sharma, S]]
-	[[Category: Singh, T P.]]	+	[[Category: Singh, T P]]
-	[[Category: Sinha, M.]]	+	[[Category: Sinha, M]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Inactivation]]		[[Category: Inactivation]]

OCA at 06:27, 5 June 2014

OCA — Thu, 05 Jun 2014 06:27:47 GMT

←Older revision		Revision as of 06:27, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3v2k.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution==
		+	<StructureSection load='3v2k' size='340' side='right' caption='[[3v2k]], [[Resolution\|resolution]] 2.07Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3V2K FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aha\|1aha]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/rRNA_N-glycosylase rRNA N-glycosylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.22 3.2.2.22] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3v2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v2k OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3v2k RCSB], [http://www.ebi.ac.uk/pdbsum/3v2k PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The ribosome inactivating proteins (RIPs) of type 1 are plant toxins that eliminate adenine base selectively from the single stranded loop of rRNA. We report six crystal structures, type 1 RIP from Momordica balsamina (A), three in complexed states with ribose (B), guanine (C) and adenine (D) and two structures of MbRIP-1 when crystallized with adenosine triphosphate (ATP) (E) and 2'-deoxyadenosine triphosphate (2'-dATP) (F). These were determined at 1.67A, 1.60A, 2.20A, 1.70A, 2.07A and 1.90A resolutions respectively. The structures contained, (A) unbound protein molecule, (B) one protein molecule and one ribose sugar, (C) one protein molecule and one guanine base, (D) one protein molecule and one adenine base, (E) one protein molecule and one ATP-product adenine molecule and (F) one protein molecule and one 2'-dATP-product adenine molecule. Three distinct conformations of the side chain of Tyr70 were observed with (i) chi(1)=-66 degrees and chi(2)=165 degrees in structures (A) and (B); (ii) chi(1)=-95 degrees and chi(2)=70 degrees in structures (C), (D) and (E); and (iii) chi(1)=-163 degrees and chi(2)=87 degrees in structure (F). The conformation of Tyr70 in (F) corresponds to the structure of a conformational intermediate. This is the first structure which demonstrates that the slow conversion of DNA substrates by RIPs can be trapped during crystallization.

-	<!--	+	Crystal structures of a type-1 ribosome inactivating protein from Momordica balsamina in the bound and unbound states.,Kushwaha GS, Pandey N, Sinha M, Singh SB, Kaur P, Sharma S, Singh TP Biochim Biophys Acta. 2012 Apr;1824(4):679-91. Epub 2012 Feb 14. PMID:22361570<ref>PMID:22361570</ref>
-	~~The line below this paragraph~~, ~~containing "STRUCTURE_3v2k"~~, ~~creates the "Structure Box" on the page~~.	+
-	~~You may change the PDB parameter~~ (~~which sets the PDB file loaded into the applet~~)	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3v2k\| PDB=3v2k \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~ribosome inactivating protein from momordica balsamina complexed with~~ the ~~product~~ of ~~RNA substrate adenosine triphosphate at 2~~.~~0 A resolution===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	<~~!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22361570}}, adds the Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http:~~/~~/www.pubmed.gov), where 22361570 is the PubMed ID number.~~	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22361570}}~~	+
-		+
-	==~~About this Structure~~==	+
-	~~[[3v2k]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA].~~	+
-		+
-	~~==Reference==~~	+
-	<~~ref group="xtra">PMID:022361570</ref><references group="xtra"~~/>	+
	[[Category: Momordica balsamina]]		[[Category: Momordica balsamina]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 06:35, 28 March 2012

OCA — Wed, 28 Mar 2012 06:35:06 GMT

←Older revision		Revision as of 06:35, 28 March 2012
Line 1:		Line 1:
-	[[Image:3v2k.~~jpg~~\|left\|200px]]	+	[[Image:3v2k.png\|left\|200px]]

	<!--		<!--
Line 11:		Line 11:
	===Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution===		===Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution===

		+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22361570}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22361570 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22361570}}

	==About this Structure==		==About this Structure==
	[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA].		[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022361570</ref><references group="xtra"/>
	[[Category: Momordica balsamina]]		[[Category: Momordica balsamina]]
	[[Category: RRNA N-glycosylase]]		[[Category: RRNA N-glycosylase]]

OCA at 10:55, 18 January 2012

OCA — Wed, 18 Jan 2012 10:55:00 GMT

←Older revision		Revision as of 10:55, 18 January 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3v2k.jpg\|left\|200px]]

-	The ~~entry 3v2k~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3v2k", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3v2k\| PDB=3v2k \| SCENE= }}

-	~~Authors: Kushwaha, G~~.~~S., Pandey, N., Sinha, M., Bhushan,~~ A~~., Kaur, P., Sharma, S., Singh, T.P.~~	+	===Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution===

-	~~Description: Crystal~~ structure ~~of ribosome inactivating protein~~ from ~~momordica~~ balsamina ~~complexed with the product of RNA substrate adenosine triphosphate at 2~~.0 A ~~resolution~~	+
		+	==About this Structure==
		+	[[3v2k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Momordica_balsamina Momordica balsamina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V2K OCA].
		+	[[Category: Momordica balsamina]]
		+	[[Category: RRNA N-glycosylase]]
		+	[[Category: Bhushan, A.]]
		+	[[Category: Kaur, P.]]
		+	[[Category: Kushwaha, G S.]]
		+	[[Category: Pandey, N.]]
		+	[[Category: Sharma, S.]]
		+	[[Category: Singh, T P.]]
		+	[[Category: Sinha, M.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Inactivation]]
		+	[[Category: Nitrogenous base]]
		+	[[Category: Plant protein]]
		+	[[Category: Ribose]]
		+	[[Category: Rip]]
		+	[[Category: Rna]]
		+	[[Category: Rna n-glycosidase]]

OCA at 05:57, 11 January 2012

OCA — Wed, 11 Jan 2012 05:57:48 GMT

←Older revision		Revision as of 05:57, 11 January 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3v2k is ON HOLD	+	The entry 3v2k is ON HOLD until Paper Publication

	Authors: Kushwaha, G.S., Pandey, N., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Singh, T.P.		Authors: Kushwaha, G.S., Pandey, N., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Singh, T.P.

	Description: Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution		Description: Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution

OCA at 05:45, 4 January 2012

OCA — Wed, 04 Jan 2012 05:45:05 GMT

←Older revision		Revision as of 05:45, 4 January 2012
Line 3:		Line 3:
	The entry 3v2k is ON HOLD		The entry 3v2k is ON HOLD

-	Authors: Kushwaha, G.S., Pandey, N . , Sinha, M. , Bhushan, A. , Kaur, P. , Sharma, S. , Singh, T.P.	+	Authors: Kushwaha, G.S., Pandey, N., Sinha, M., Bhushan, A., Kaur, P., Sharma, S., Singh, T.P.

	Description: Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution		Description: Crystal structure of ribosome inactivating protein from momordica balsamina complexed with the product of RNA substrate adenosine triphosphate at 2.0 A resolution

OCA: Protected "3v2k" [edit=sysop:move=sysop]

OCA — Wed, 28 Dec 2011 06:48:12 GMT

Protected "3v2k" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:48, 28 December 2011