3vdj - Revision history

OCA at 14:25, 14 March 2024

OCA — Thu, 14 Mar 2024 14:25:42 GMT

←Older revision		Revision as of 14:25, 14 March 2024
Line 3:		Line 3:
	<StructureSection load='3vdj' size='340' side='right'caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3vdj' size='340' side='right'caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Plaf7 Plaf7~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[3vdk\|3vdk]], [[3vdl\|3vdl]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.698Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">PFC0210c ([https://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=36329 PLAF7])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [https://pdbe.org/3vdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [https://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [https://pdbe.org/3vdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [https://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/CSP_PLAF7 CSP_PLAF7] Essential sporozoite protein (PubMed:29554084, PubMed:32150583). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (PubMed:29554084, PubMed:32150583). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).[UniProtKB:P23093]<ref>PMID:29554084</ref> <ref>PMID:32150583</ref> In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[UniProtKB:P23093]
-	~~Circumsporozoite~~ (CS) ~~protein is~~ the ~~major surface component of Plasmodium falciparum sporozoites and is essential~~ for ~~host cell invasion. A vaccine containing tandem repeats, region III~~, and ~~thrombospondin type-I repeat~~ (~~TSR~~) ~~of CS is efficacious in phase III trials but gives only a 35% reduction in severe malaria in~~ the ~~first year postimmunization. We solved crystal structures showing that region III and TSR fold into a single unit~~, an "alphaTSR" domain. The alphaTSR domain possesses a hydrophobic pocket and core, missing in TSR domains. CS binds heparin, but alphaTSR does not. Interestingly, polymorphic T-cell epitopes map to specialized alphaTSR regions. The N and C termini are unexpectedly close, providing clues for sporozoite ~~sheath organization. Elucidation of a unique structure of a domain within CS enables rational design of next-generation subunit vaccines~~ and ~~functional and medicinal chemical investigation~~ of ~~the conserved hydrophobic pocket~~.	+
-		+
-	~~Unexpected fold in~~ the ~~circumsporozoite protein target~~ of ~~malaria vaccines.,Doud MB, Koksal AC, Mi LZ, Song G, Lu C, Springer TA Proc Natl Acad Sci U S A. 2012 Apr 30~~. PMID:~~22547819~~<ref>PMID:~~22547819~~</ref>	+
-		+
-	~~From MEDLINE®/PubMed®~~, ~~a database~~ of the U.~~S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3vdj" style="background-color~~:~~#fffaf0;"></div>~~	+
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Plaf7~~]]	+	[[Category: Plasmodium falciparum 3D7]]
-	[[Category: Doud~~, M B~~]]	+	[[Category: Doud MB]]
-	[[Category: Koksal~~, A C~~]]	+	[[Category: Koksal AC]]
-	[[Category: Lu, C]]	+	[[Category: Lu C]]
-	[[Category: Mi~~, L Z~~]]	+	[[Category: Mi LZ]]
-	[[Category: Song, G]]	+	[[Category: Song G]]
-	[[Category: Springer~~, T A]]~~	+	[[Category: Springer TA]]
-	~~[[Category: Atsr]]~~	+
-	~~[[Category: Cell invasion]]~~	+
-	~~[[Category: Tsr~~]]	+

OCA at 18:39, 27 July 2022

OCA — Wed, 27 Jul 2022 18:39:51 GMT

←Older revision		Revision as of 18:39, 27 July 2022
Line 1:		Line 1:

	==Crystal structure of circumsporozoite protein aTSR domain, R32 native form==		==Crystal structure of circumsporozoite protein aTSR domain, R32 native form==
-	<StructureSection load='3vdj' size='340' side='right' caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>	+	<StructureSection load='3vdj' size='340' side='right'caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vdk\|3vdk]], [[3vdl\|3vdl]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [~~http~~://pdbe.org/3vdj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [https://pdbe.org/3vdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [https://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Plaf7]]		[[Category: Plaf7]]
	[[Category: Doud, M B]]		[[Category: Doud, M B]]

OCA at 09:54, 11 August 2016

OCA — Thu, 11 Aug 2016 09:54:46 GMT

←Older revision		Revision as of 09:54, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of circumsporozoite protein aTSR domain, R32 native form==		==Crystal structure of circumsporozoite protein aTSR domain, R32 native form==
	<StructureSection load='3vdj' size='340' side='right' caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>		<StructureSection load='3vdj' size='340' side='right' caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Plasmodium_falciparum Plasmodium falciparum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plaf7 Plaf7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~5833 Plasmodium falciparum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=36329 PLAF7])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [http://www.ebi.ac.uk/pdbsum/3vdj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [http://pdbe.org/3vdj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [http://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vdj" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Plasmodium falciparum~~]]	+	[[Category: Plaf7]]
	[[Category: Doud, M B]]		[[Category: Doud, M B]]
	[[Category: Koksal, A C]]		[[Category: Koksal, A C]]

OCA at 10:20, 4 January 2015

OCA — Sun, 04 Jan 2015 10:20:08 GMT

←Older revision		Revision as of 10:20, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [http://www.ebi.ac.uk/pdbsum/3vdj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [http://www.ebi.ac.uk/pdbsum/3vdj PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 13:		Line 13:
	Unexpected fold in the circumsporozoite protein target of malaria vaccines.,Doud MB, Koksal AC, Mi LZ, Song G, Lu C, Springer TA Proc Natl Acad Sci U S A. 2012 Apr 30. PMID:22547819<ref>PMID:22547819</ref>		Unexpected fold in the circumsporozoite protein target of malaria vaccines.,Doud MB, Koksal AC, Mi LZ, Song G, Lu C, Springer TA Proc Natl Acad Sci U S A. 2012 Apr 30. PMID:22547819<ref>PMID:22547819</ref>

-	From ~~MEDLINEÂ®~~/~~PubMedÂ®~~, a database of the U.S. National Library of Medicine.<br>	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
	== References ==		== References ==
Line 20:		Line 20:
	</StructureSection>		</StructureSection>
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
-	[[Category: Doud, M B.]]	+	[[Category: Doud, M B]]
-	[[Category: Koksal, A C.]]	+	[[Category: Koksal, A C]]
-	[[Category: Lu, C.]]	+	[[Category: Lu, C]]
-	[[Category: Mi, L Z.]]	+	[[Category: Mi, L Z]]
-	[[Category: Song, G.]]	+	[[Category: Song, G]]
-	[[Category: Springer, T A.]]	+	[[Category: Springer, T A]]
	[[Category: Atsr]]		[[Category: Atsr]]
	[[Category: Cell invasion]]		[[Category: Cell invasion]]
	[[Category: Tsr]]		[[Category: Tsr]]

OCA at 07:20, 5 June 2014

OCA — Thu, 05 Jun 2014 07:20:21 GMT

←Older revision		Revision as of 07:20, 5 June 2014
Line 1:		Line 1:
-	[[~~Image:~~3vdj.~~png~~\|~~left~~\|~~200px~~]]	+	==Crystal structure of circumsporozoite protein aTSR domain, R32 native form==
		+	<StructureSection load='3vdj' size='340' side='right' caption='[[3vdj]], [[Resolution\|resolution]] 1.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VDJ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vdk\|3vdk]], [[3vdl\|3vdl]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PFC0210c ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [http://www.ebi.ac.uk/pdbsum/3vdj PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Circumsporozoite (CS) protein is the major surface component of Plasmodium falciparum sporozoites and is essential for host cell invasion. A vaccine containing tandem repeats, region III, and thrombospondin type-I repeat (TSR) of CS is efficacious in phase III trials but gives only a 35% reduction in severe malaria in the first year postimmunization. We solved crystal structures showing that region III and TSR fold into a single unit, an "alphaTSR" domain. The alphaTSR domain possesses a hydrophobic pocket and core, missing in TSR domains. CS binds heparin, but alphaTSR does not. Interestingly, polymorphic T-cell epitopes map to specialized alphaTSR regions. The N and C termini are unexpectedly close, providing clues for sporozoite sheath organization. Elucidation of a unique structure of a domain within CS enables rational design of next-generation subunit vaccines and functional and medicinal chemical investigation of the conserved hydrophobic pocket.

-	~~<!--~~	+	Unexpected fold in the circumsporozoite protein target of malaria vaccines.,Doud MB, Koksal AC, Mi LZ, Song G, Lu C, Springer TA Proc Natl Acad Sci U S A. 2012 Apr 30. PMID:22547819<ref>PMID:22547819</ref>
-	~~The line below this paragraph, containing "STRUCTURE_3vdj", creates the "Structure Box" on~~ the ~~page~~.	+
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded)~~,	+
-	~~or leave the SCENE parameter empty for the default display~~.	+
-	-->	+
-	~~{{STRUCTURE_3vdj\| PDB=3vdj \| SCENE= }}~~	+

-	~~===Crystal structure~~ of ~~circumsporozoite protein aTSR domain, R32 native form===~~	+	From MEDLINEÂ®/PubMedÂ®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-		+	== References ==
-	~~<!--~~	+	<references/>
-	~~The line below this paragraph, {{ABSTRACT_PUBMED_22547819}}, adds~~ the ~~Publication Abstract to the page~~	+	__TOC__
-	~~(as it appears on PubMed at http://www~~.~~pubmed~~.~~gov), where 22547819 is the PubMed ID number~~.	+	</StructureSection>
-	-->	+
-	~~{{ABSTRACT_PUBMED_22547819}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[3vdj]] is a 1 chain structure with sequence from [http:~~/~~/en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA].~~	+
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:022547819<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Plasmodium falciparum]]		[[Category: Plasmodium falciparum]]
	[[Category: Doud, M B.]]		[[Category: Doud, M B.]]

OCA at 05:00, 30 May 2012

OCA — Wed, 30 May 2012 05:00:09 GMT

←Older revision		Revision as of 05:00, 30 May 2012
Line 1:		Line 1:
-	[[Image:3vdj.~~jpg~~\|left\|200px]]	+	[[Image:3vdj.png\|left\|200px]]

	<!--		<!--

OCA at 09:11, 9 May 2012

OCA — Wed, 09 May 2012 09:11:36 GMT

←Older revision		Revision as of 09:11, 9 May 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3vdj.jpg\|left\|200px]]

-	The ~~entry 3vdj~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3vdj", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3vdj\| PDB=3vdj \| SCENE= }}

-	~~Authors: Doud~~, ~~M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.~~	+	===Crystal structure of circumsporozoite protein aTSR domain, R32 native form===

-	~~Description~~: ~~Crystal~~ structure ~~of circumsporozoite protein aTSR domain~~, ~~R32 native form~~	+
		+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_22547819}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 22547819 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_22547819}}
		+
		+	==About this Structure==
		+	[[3vdj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:022547819</ref><references group="xtra"/>
		+	[[Category: Plasmodium falciparum]]
		+	[[Category: Doud, M B.]]
		+	[[Category: Koksal, A C.]]
		+	[[Category: Lu, C.]]
		+	[[Category: Mi, L Z.]]
		+	[[Category: Song, G.]]
		+	[[Category: Springer, T A.]]
		+	[[Category: Atsr]]
		+	[[Category: Cell invasion]]
		+	[[Category: Tsr]]

OCA at 10:20, 18 January 2012

OCA — Wed, 18 Jan 2012 10:20:03 GMT

←Older revision		Revision as of 10:20, 18 January 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vdj is ON HOLD	+	The entry 3vdj is ON HOLD until Paper Publication

-	Authors: Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Springer, T.A.	+	Authors: Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Lu, C., Springer, T.A.

-	Description: ~~A novel fold in the~~ circumsporozoite protein ~~target of malaria vaccines~~	+	Description: Crystal structure of circumsporozoite protein aTSR domain, R32 native form

OCA: Protected "3vdj" [edit=sysop:move=sysop]

OCA — Wed, 11 Jan 2012 06:02:31 GMT

Protected "3vdj" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:02, 11 January 2012

OCA: New page: '''Unreleased structure''' The entry 3vdj is ON HOLD Authors: Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Springer, T.A. Description: A novel fold in the circumsporozoite protein tar...

OCA — Wed, 11 Jan 2012 06:02:30 GMT

New page: '''Unreleased structure''' The entry 3vdj is ON HOLD Authors: Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Springer, T.A. Description: A novel fold in the circumsporozoite protein tar...

New page

'''Unreleased structure'''

The entry 3vdj is ON HOLD

Authors: Doud, M.B., Koksal, A.C., Mi, L.Z., Song, G., Springer, T.A.

Description: A novel fold in the circumsporozoite protein target of malaria vaccines