3vnz - Revision history

OCA at 12:29, 8 November 2023

OCA — Wed, 08 Nov 2023 12:29:19 GMT

←Older revision		Revision as of 12:29, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3vnz' size='340' side='right'caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3vnz' size='340' side='right'caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Acic5 Acic5~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidobacterium_capsulatum_ATCC_51196 Acidobacterium capsulatum ATCC 51196]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=BDP:BETA~~-~~D-GLUCOPYRANURONIC+ACID'>BDP</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3vny\|3vny]], [[3vo0\|3vo0]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td><~~td class="sblockDat">ACP_2665 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [https://pdbe.org/3vnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [https://www.ebi.ac.uk/pdbsum/3vnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vnz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [https://pdbe.org/3vnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [https://www.ebi.ac.uk/pdbsum/3vnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vnz ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/C1F2K5_ACIC5 C1F2K5_ACIC5]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acic5]]~~	+	[[Category: Acidobacterium capsulatum ATCC 51196]]
-	~~[[Category: Beta-glucuronidase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Biely, P]]	+	[[Category: Biely P]]
-	[[Category: Fujimoto, Z]]	+	[[Category: Fujimoto Z]]
-	[[Category: Ichinose, H]]	+	[[Category: Ichinose H]]
-	[[Category: Kaneko, S]]	+	[[Category: Kaneko S]]
-	[[Category: Kotake, Y]]	+	[[Category: Kotake Y]]
-	[[Category: Michikawa, M]]	+	[[Category: Michikawa M]]
-	[[Category: Momma, M]]	+	[[Category: Momma M]]
-	[[Category: Tsumuraya, Y]]	+	[[Category: Tsumuraya Y]]
-	[[Category: Yoshida, M]]	+	[[Category: Yoshida M]]
-	~~[[Category: Glycoside hydrolase family 79]]~~	+
-	~~[[Category: Greek-key]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Tim barrel~~]]	+

OCA at 18:55, 27 July 2022

OCA — Wed, 27 Jul 2022 18:55:01 GMT

←Older revision		Revision as of 18:55, 27 July 2022
Line 1:		Line 1:

	==Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid==		==Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid==
-	<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='3vnz' size='340' side='right'caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Acic5 Acic5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acic5 Acic5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vny\|3vny]], [[3vo0\|3vo0]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [~~http~~://pdbe.org/3vnz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vnz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vnz ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [https://pdbe.org/3vnz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [https://www.ebi.ac.uk/pdbsum/3vnz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vnz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	==See Also==		==See Also==
	*[[Glucuronidase\|Glucuronidase]]		*[[Glucuronidase\|Glucuronidase]]
		+	*[[Glucuronisidase 3D structures\|Glucuronisidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 28:		Line 29:
	[[Category: Acic5]]		[[Category: Acic5]]
	[[Category: Beta-glucuronidase]]		[[Category: Beta-glucuronidase]]
		+	[[Category: Large Structures]]
	[[Category: Biely, P]]		[[Category: Biely, P]]
	[[Category: Fujimoto, Z]]		[[Category: Fujimoto, Z]]

OCA at 14:14, 24 May 2017

OCA — Wed, 24 May 2017 14:14:20 GMT

←Older revision		Revision as of 14:14, 24 May 2017
Line 1:		Line 1:
		+
	==Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid==		==Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid==
	<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://pdbe.org/3vnz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vnz ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vnz" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:24, 20 August 2015

OCA — Thu, 20 Aug 2015 06:24:14 GMT

←Older revision		Revision as of 06:24, 20 August 2015
Line 2:		Line 2:
	<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Acidobacterium_capsulatum Acidobacterium capsulatum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acic5 Acic5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~33075 Acidobacterium capsulatum~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=240015 ACIC5])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We present the first structure of a glycoside hydrolase family 79 beta-glucuronidase from Acidobacterium capsulatum, both as a product complex with beta-D-glucuronic acid (GlcA) and as its trapped covalent 2-fluoroglucuronyl intermediate. This enzyme consists of a catalytic (beta/alpha)(8)-barrel domain and a beta-domain with irregular Greek key motifs that is of unknown function. The enzyme showed beta-glucuronidase activity and trace levels of beta-glucosidase and beta-xylosidase activities. In conjunction with mutagenesis studies, these structures identify the catalytic residues as Glu(173) (acid base) and Glu(287) (nucleophile), consistent with the retaining mechanism demonstrated by (1)H NMR analysis. Glu(45), Tyr(243), Tyr(292)-Gly(294), and Tyr(334) form the catalytic pocket and provide substrate discrimination. Consistent with this, the Y292A mutation, which affects the interaction between the main chains of Gln(293) and Gly(294) and the GlcA carboxyl group, resulted in significant loss of beta-glucuronidase activity while retaining the side activities at wild-type levels. Likewise, although the beta-glucuronidase activity of the Y334F mutant is ~200-fold lower (k(cat)/K(m)) than that of the wild-type enzyme, the beta-glucosidase activity is actually 3 times higher and the beta-xylosidase activity is only 2.5-fold lower than the equivalent parameters for wild type, consistent with a role for Tyr(334) in recognition of the C6 position of GlcA. The involvement of Glu(45) in discriminating against binding of the O-methyl group at the C4 position of GlcA is revealed in the fact that the E45D mutant hydrolyzes PNP-beta-GlcA approximately 300-fold slower (k(cat)/K(m)) than does the wild-type enzyme, whereas 4-O-methyl-GlcA-containing oligosaccharides are hydrolyzed only 7-fold slower.
		+
		+	Structural and biochemical characterization of glycoside hydrolase family 79 beta-glucuronidase from Acidobacterium capsulatum.,Michikawa M, Ichinose H, Momma M, Biely P, Jongkees S, Yoshida M, Kotake T, Tsumuraya Y, Withers SG, Fujimoto Z, Kaneko S J Biol Chem. 2012 Apr 20;287(17):14069-77. Epub 2012 Feb 24. PMID:22367201<ref>PMID:22367201</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Glucuronidase\|Glucuronidase]]		*[[Glucuronidase\|Glucuronidase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Acidobacterium capsulatum~~]]	+	[[Category: Acic5]]
	[[Category: Beta-glucuronidase]]		[[Category: Beta-glucuronidase]]
	[[Category: Biely, P]]		[[Category: Biely, P]]

OCA at 10:36, 4 January 2015

OCA — Sun, 04 Jan 2015 10:36:28 GMT

←Older revision		Revision as of 10:36, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidobacterium_capsulatum Acidobacterium capsulatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidobacterium_capsulatum Acidobacterium capsulatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33075 Acidobacterium capsulatum])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33075 Acidobacterium capsulatum])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>
-	<table>	+	</table>
		+
		+	==See Also==
		+	*[[Glucuronidase\|Glucuronidase]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Acidobacterium capsulatum]]		[[Category: Acidobacterium capsulatum]]
	[[Category: Beta-glucuronidase]]		[[Category: Beta-glucuronidase]]
-	[[Category: Biely, P.]]	+	[[Category: Biely, P]]
-	[[Category: Fujimoto, Z.]]	+	[[Category: Fujimoto, Z]]
-	[[Category: Ichinose, H.]]	+	[[Category: Ichinose, H]]
-	[[Category: Kaneko, S.]]	+	[[Category: Kaneko, S]]
-	[[Category: Kotake, Y.]]	+	[[Category: Kotake, Y]]
-	[[Category: Michikawa, M.]]	+	[[Category: Michikawa, M]]
-	[[Category: Momma, M.]]	+	[[Category: Momma, M]]
-	[[Category: Tsumuraya, Y.]]	+	[[Category: Tsumuraya, Y]]
-	[[Category: Yoshida, M.]]	+	[[Category: Yoshida, M]]
	[[Category: Glycoside hydrolase family 79]]		[[Category: Glycoside hydrolase family 79]]
	[[Category: Greek-key]]		[[Category: Greek-key]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Tim barrel]]		[[Category: Tim barrel]]

OCA at 07:40, 5 June 2014

OCA — Thu, 05 Jun 2014 07:40:37 GMT

←Older revision		Revision as of 07:40, 5 June 2014
Line 1:		Line 1:
-	~~[[Image:3vnz.jpg\|left\|200px]]~~	+	==Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid==
-		+	<StructureSection load='3vnz' size='340' side='right' caption='[[3vnz]], [[Resolution\|resolution]] 1.80Å' scene=''>
-	~~<!--~~	+	== Structural highlights ==
-	~~The line below this paragraph, containing "STRUCTURE_3vnz", creates the "Structure Box" on the page.~~	+	<table><tr><td colspan='2'>[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidobacterium_capsulatum Acidobacterium capsulatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VNZ FirstGlance]. <br>
-	~~You may change the PDB parameter (which sets the PDB file loaded into the applet)~~	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BDP:BETA-D-GLUCOPYRANURONIC+ACID'>BDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene><br>
-	~~or the SCENE parameter (which sets the initial scene displayed when the page is loaded),~~	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vny\|3vny]], [[3vo0\|3vo0]]</td></tr>
-	~~or leave the SCENE parameter empty for the default display.~~	+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ACP_2665 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=33075 Acidobacterium capsulatum])</td></tr>
-	~~-->~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucuronidase Beta-glucuronidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.31 3.2.1.31] </span></td></tr>
-	~~{{STRUCTURE_3vnz\| PDB=3vnz \| SCENE= }}~~	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vnz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vnz OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vnz RCSB], [http://www.ebi.ac.uk/pdbsum/3vnz PDBsum]</span></td></tr>
-		+	<table>
-	===Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid===	+	__TOC__
-		+	</StructureSection>
-		+
-	==~~About this Structure~~==	+
-	[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidobacterium_capsulatum Acidobacterium capsulatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA].	+
	[[Category: Acidobacterium capsulatum]]		[[Category: Acidobacterium capsulatum]]
	[[Category: Beta-glucuronidase]]		[[Category: Beta-glucuronidase]]

OCA at 08:01, 22 February 2012

OCA — Wed, 22 Feb 2012 08:01:47 GMT

←Older revision		Revision as of 08:01, 22 February 2012
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3vnz.jpg\|left\|200px]]

-	The ~~entry 3vnz~~ is ~~ON HOLD~~ ~~until Paper Publication~~	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_3vnz", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_3vnz\| PDB=3vnz \| SCENE= }}

-	~~Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S.~~	+	===Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid===

-	~~Description: Crystal~~ structure ~~of beta-glucuronidase~~ from Acidobacterium capsulatum ~~in complex with D~~-~~glucuronic acid~~	+
		+	==About this Structure==
		+	[[3vnz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Acidobacterium_capsulatum Acidobacterium capsulatum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VNZ OCA].
		+	[[Category: Acidobacterium capsulatum]]
		+	[[Category: Beta-glucuronidase]]
		+	[[Category: Biely, P.]]
		+	[[Category: Fujimoto, Z.]]
		+	[[Category: Ichinose, H.]]
		+	[[Category: Kaneko, S.]]
		+	[[Category: Kotake, Y.]]
		+	[[Category: Michikawa, M.]]
		+	[[Category: Momma, M.]]
		+	[[Category: Tsumuraya, Y.]]
		+	[[Category: Yoshida, M.]]
		+	[[Category: Glycoside hydrolase family 79]]
		+	[[Category: Greek-key]]
		+	[[Category: Hydrolase]]
		+	[[Category: Tim barrel]]

OCA at 06:15, 15 February 2012

OCA — Wed, 15 Feb 2012 06:15:33 GMT

←Older revision		Revision as of 06:15, 15 February 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vnz is ON HOLD	+	The entry 3vnz is ON HOLD until Paper Publication

	Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S.		Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S.

	Description: Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid		Description: Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid

OCA: Protected "3vnz" [edit=sysop:move=sysop]

OCA — Wed, 25 Jan 2012 06:05:59 GMT

Protected "3vnz" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:05, 25 January 2012

OCA: New page: '''Unreleased structure''' The entry 3vnz is ON HOLD Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S. Descri...

OCA — Wed, 25 Jan 2012 06:05:58 GMT

New page: '''Unreleased structure''' The entry 3vnz is ON HOLD Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S. Descri...

New page

'''Unreleased structure'''

The entry 3vnz is ON HOLD

Authors: Momma, M., Fujimoto, Z., Michikawa, M., Ichinose, H., Yoshida, M., Kotake, Y., Biely, P., Tsumuraya, Y., Kaneko, S.

Description: Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with D-glucuronic acid