3vq8 - Revision history

OCA at 12:32, 8 November 2023

OCA — Wed, 08 Nov 2023 12:32:36 GMT

←Older revision		Revision as of 12:32, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3vq8' size='340' side='right'caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3vq8' size='340' side='right'caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~9hiv1 9hiv1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [https://pdbe.org/3vq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [https://www.ebi.ac.uk/pdbsum/3vq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vq8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [https://pdbe.org/3vq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [https://www.ebi.ac.uk/pdbsum/3vq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vq8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q72498_9HIV1 Q72498_9HIV1]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human immunodeficiency virus 1]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chalmers~~, D K~~]]	+	[[Category: Chalmers DK]]
-	[[Category: Parker~~, M W~~]]	+	[[Category: Parker MW]]
-	[[Category: Scanlon~~, M J~~]]	+	[[Category: Scanlon MJ]]
-	[[Category: Wielens, J]]	+	[[Category: Wielens J]]
-	~~[[Category: Dna binding]]~~	+
-	~~[[Category: Dna cleavage]]~~	+
-	~~[[Category: Dna integration]]~~	+
-	~~[[Category: Rnaseh]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 18:58, 27 July 2022

OCA — Wed, 27 Jul 2022 18:58:08 GMT

←Older revision		Revision as of 18:58, 27 July 2022
Line 1:		Line 1:

	==HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol==		==HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol==
-	<StructureSection load='3vq8' size='340' side='right' caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='3vq8' size='340' side='right'caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [~~http~~://pdbe.org/3vq8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vq8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vq8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [https://pdbe.org/3vq8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [https://www.ebi.ac.uk/pdbsum/3vq8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vq8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chalmers, D K]]		[[Category: Chalmers, D K]]
	[[Category: Parker, M W]]		[[Category: Parker, M W]]

OCA at 19:06, 10 December 2016

OCA — Sat, 10 Dec 2016 19:06:08 GMT

←Older revision		Revision as of 19:06, 10 December 2016
Line 1:		Line 1:
		+
	==HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol==		==HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol==
	<StructureSection load='3vq8' size='340' side='right' caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='3vq8' size='340' side='right' caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Human_immunodeficiency_virus_1 Human immunodeficiency virus 1~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 ~~Human immunodeficiency virus 1~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 9HIV1])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [http://www.ebi.ac.uk/pdbsum/3vq8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [http://pdbe.org/3vq8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [http://www.ebi.ac.uk/pdbsum/3vq8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vq8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vq8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Human immunodeficiency virus 1]]
	[[Category: Chalmers, D K]]		[[Category: Chalmers, D K]]
	[[Category: Parker, M W]]		[[Category: Parker, M W]]

OCA at 16:47, 9 December 2014

OCA — Tue, 09 Dec 2014 16:47:18 GMT

←Older revision		Revision as of 16:47, 9 December 2014
Line 1:		Line 1:
-	[[~~Image:~~3vq8.~~jpg~~\|~~left~~\|~~200px~~]]	+	==HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol==
		+	<StructureSection load='3vq8' size='340' side='right' caption='[[3vq8]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[3vq8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VQ8 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCU:(3R)-3,4-DIHYDRO-2H-CHROMEN-3-YLMETHANOL'>BCU</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3l3u\|3l3u]], [[3l3v\|3l3v]], [[3ovn\|3ovn]], [[3vq4\|3vq4]], [[3vq5\|3vq5]], [[3vq6\|3vq6]], [[3vq7\|3vq7]], [[3vq9\|3vq9]], [[3vqa\|3vqa]], [[3vqb\|3vqb]], [[3vqc\|3vqc]], [[3vqd\|3vqd]], [[3vqe\|3vqe]], [[3vqp\|3vqp]], [[3vqq\|3vqq]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vq8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vq8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vq8 RCSB], [http://www.ebi.ac.uk/pdbsum/3vq8 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fragment screening is becoming widely accepted as a technique to identify hit compounds for the development of novel lead compounds. In neighboring laboratories, we have recently, and independently, performed a fragment screening campaign on the HIV-1 integrase core domain (IN) using similar commercially purchased fragment libraries. The two campaigns used different screening methods for the preliminary identification of fragment hits; one used saturation transfer difference nuclear magnetic resonance spectroscopy (STD-NMR), and the other used surface plasmon resonance (SPR) spectroscopy. Both initial screens were followed by X-ray crystallography. Using the STD-NMR/X-ray approach, 15 IN/fragment complexes were identified, whereas the SPR/X-ray approach found 6 complexes. In this article, we compare the approaches that were taken by each group and the results obtained, and we look at what factors could potentially influence the final results. We find that despite using different approaches with little overlap of initial hits, both approaches identified binding sites on IN that provided a basis for fragment-based lead discovery and further lead development. Comparison of hits identified in the two studies highlights a key role for both the conditions under which fragment binding is measured and the criteria selected to classify hits.

-	~~{{STRUCTURE_3vq8\| PDB=3vq8 \| SCENE= }}~~	+	Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification?,Wielens J, Headey SJ, Rhodes DI, Mulder RJ, Dolezal O, Deadman JJ, Newman J, Chalmers DK, Parker MW, Peat TS, Scanlon MJ J Biomol Screen. 2012 Nov 13. PMID:23139382<ref>PMID:23139382</ref>

-	~~===HIV-1 IN core domain in complex with (3R)-3~~,~~4-dihydro-2H-chromen-3-ylmethanol===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_23139382}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[3vq8]] is a 2 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA].~~	+	</StructureSection>
	[[Category: Human immunodeficiency virus 1]]		[[Category: Human immunodeficiency virus 1]]
-	[[Category: Chalmers, D K.]]	+	[[Category: Chalmers, D K]]
-	[[Category: Parker, M W.]]	+	[[Category: Parker, M W]]
-	[[Category: Scanlon, M J.]]	+	[[Category: Scanlon, M J]]
-	[[Category: Wielens, J.]]	+	[[Category: Wielens, J]]
	[[Category: Dna binding]]		[[Category: Dna binding]]
	[[Category: Dna cleavage]]		[[Category: Dna cleavage]]

OCA at 12:23, 30 January 2013

OCA — Wed, 30 Jan 2013 12:23:50 GMT

←Older revision		Revision as of 12:23, 30 January 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	[[Image:3vq8.jpg\|left\|200px]]

-	~~The entry~~ 3vq8 ~~is ON HOLD~~ ~~until Paper Publication~~	+	{{STRUCTURE_3vq8\| PDB=3vq8 \| SCENE= }}

-	~~Authors: Wielens~~, ~~J., Chalmers, D.K., Parker, M.W., Scanlon, M.J.~~	+	===HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol===

-	~~Description~~: ~~HIV-~~1 ~~IN core domain in complex with (3R)~~-3,4-~~dihydro-2H-chromen-3-ylmethanol~~	+	{{ABSTRACT_PUBMED_23139382}}
		+
		+	==About this Structure==
		+	[[3vq8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQ8 OCA].
		+	[[Category: Human immunodeficiency virus 1]]
		+	[[Category: Chalmers, D K.]]
		+	[[Category: Parker, M W.]]
		+	[[Category: Scanlon, M J.]]
		+	[[Category: Wielens, J.]]
		+	[[Category: Dna binding]]
		+	[[Category: Dna cleavage]]
		+	[[Category: Dna integration]]
		+	[[Category: Rnaseh]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA at 05:17, 30 May 2012

OCA — Wed, 30 May 2012 05:17:59 GMT

←Older revision		Revision as of 05:17, 30 May 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vq8 is ON HOLD	+	The entry 3vq8 is ON HOLD until Paper Publication

	Authors: Wielens, J., Chalmers, D.K., Parker, M.W., Scanlon, M.J.		Authors: Wielens, J., Chalmers, D.K., Parker, M.W., Scanlon, M.J.

-	Description: ~~Fragments bound to~~ HIV-1 ~~integrase~~	+	Description: HIV-1 IN core domain in complex with (3R)-3,4-dihydro-2H-chromen-3-ylmethanol

OCA at 06:31, 11 April 2012

OCA — Wed, 11 Apr 2012 06:31:48 GMT

←Older revision		Revision as of 06:31, 11 April 2012
Line 3:		Line 3:
	The entry 3vq8 is ON HOLD		The entry 3vq8 is ON HOLD

-	Authors: Wielens, J, Chalmers, D.K., Parker, M.W., Scanlon, M.J.	+	Authors: Wielens, J., Chalmers, D.K., Parker, M.W., Scanlon, M.J.

	Description: Fragments bound to HIV-1 integrase		Description: Fragments bound to HIV-1 integrase

OCA: Protected "3vq8" [edit=sysop:move=sysop]

OCA — Wed, 28 Mar 2012 07:14:53 GMT

Protected "3vq8" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:14, 28 March 2012

OCA: New page: '''Unreleased structure''' The entry 3vq8 is ON HOLD Authors: Wielens, J, Chalmers, D.K., Parker, M.W., Scanlon, M.J. Description: Fragments bound to HIV-1 integrase

OCA — Wed, 28 Mar 2012 07:14:52 GMT

New page: '''Unreleased structure''' The entry 3vq8 is ON HOLD Authors: Wielens, J, Chalmers, D.K., Parker, M.W., Scanlon, M.J. Description: Fragments bound to HIV-1 integrase

New page

'''Unreleased structure'''

The entry 3vq8 is ON HOLD

Authors: Wielens, J, Chalmers, D.K., Parker, M.W., Scanlon, M.J.

Description: Fragments bound to HIV-1 integrase