3vtm - Revision history

OCA at 12:37, 8 November 2023

OCA — Wed, 08 Nov 2023 12:37:33 GMT

←Older revision		Revision as of 12:37, 8 November 2023
Line 3:		Line 3:
	<StructureSection load='3vtm' size='340' side='right'caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3vtm' size='340' side='right'caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Staam Staam~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_Mu50 Staphylococcus aureus subsp. aureus Mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VTM FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [https://pdbe.org/3vtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [https://www.ebi.ac.uk/pdbsum/3vtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtm ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [https://pdbe.org/3vtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [https://www.ebi.ac.uk/pdbsum/3vtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).	+	[https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 28:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Staam~~]]	+	[[Category: Staphylococcus aureus subsp. aureus Mu50]]
-	[[Category: Caaveiro~~, J M.M~~]]	+	[[Category: Caaveiro JMM]]
-	[[Category: Moriwaki, Y]]	+	[[Category: Moriwaki Y]]
-	[[Category: Tsumoto, K]]	+	[[Category: Tsumoto K]]
-	[[Category: Vu~~, N T]]~~	+	[[Category: Vu NT]]
-	~~[[Category: Cell wall]]~~	+
-	~~[[Category: Heme binding]]~~	+
-	~~[[Category: Heme transport]]~~	+
-	~~[[Category: Heme-binding protein]]~~	+
-	~~[[Category: Hemin]]~~	+
-	~~[[Category: Indium]]~~	+
-	~~[[Category: Metal selectivity]]~~	+
-	~~[[Category: Metalloporphyrin]]~~	+
-	~~[[Category: Neat domain]]~~	+
-	~~[[Category: Ppix~~]]	+

OCA at 19:03, 27 July 2022

OCA — Wed, 27 Jul 2022 19:03:33 GMT

←Older revision		Revision as of 19:03, 27 July 2022
Line 1:		Line 1:

	==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin==		==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin==
-	<StructureSection load='3vtm' size='340' side='right' caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>	+	<StructureSection load='3vtm' size='340' side='right'caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3VTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VTM FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [~~http~~://pdbe.org/3vtm PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3vtm PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtm ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [https://pdbe.org/3vtm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [https://www.ebi.ac.uk/pdbsum/3vtm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).	+	[[https://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 3vtm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3vtm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Haptoglobin receptor\|Haptoglobin receptor]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Staam]]		[[Category: Staam]]
	[[Category: Caaveiro, J M.M]]		[[Category: Caaveiro, J M.M]]

OCA at 07:57, 22 November 2017

OCA — Wed, 22 Nov 2017 07:57:54 GMT

←Older revision		Revision as of 07:57, 22 November 2017
Line 20:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 3vtm" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3vtm" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Haptoglobin receptor\|Haptoglobin receptor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:27, 5 August 2016

OCA — Fri, 05 Aug 2016 09:27:44 GMT

←Older revision		Revision as of 09:27, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin==		==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin==
	<StructureSection load='3vtm' size='340' side='right' caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>		<StructureSection load='3vtm' size='340' side='right' caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VTM FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staam Staam]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VTM FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 ~~Staphylococcus aureus subsp. aureus Mu50~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 STAAM])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [http://www.ebi.ac.uk/pdbsum/3vtm PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [http://pdbe.org/3vtm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [http://www.ebi.ac.uk/pdbsum/3vtm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3vtm ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3vtm" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Haptoglobin receptor\|Haptoglobin receptor]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Staphylococcus aureus subsp. aureus mu50~~]]	+	[[Category: Staam]]
	[[Category: Caaveiro, J M.M]]		[[Category: Caaveiro, J M.M]]
	[[Category: Moriwaki, Y]]		[[Category: Moriwaki, Y]]

OCA at 17:40, 25 December 2014

OCA — Thu, 25 Dec 2014 17:40:11 GMT

←Older revision		Revision as of 17:40, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3vtm\| PDB=3vtm \| SCENE= }}~~	+	==Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin==
-	===Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin===	+	<StructureSection load='3vtm' size='340' side='right' caption='[[3vtm]], [[Resolution\|resolution]] 2.80Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23649633}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3VTM FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3ZZ:PROTOPORPHYRIN+IX+CONTAINING+INDIUM'>3ZZ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qug\|3qug]], [[3quh\|3quh]], [[2e7d\|2e7d]], [[2z6f\|2z6f]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">harA, isdH, IsdH-NEAT3, sasI, SAV1731 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3vtm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vtm OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3vtm RCSB], [http://www.ebi.ac.uk/pdbsum/3vtm PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).		[[http://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Isd (iron-regulated surface determinant) system of the human pathogen Staphylococcus aureus is responsible for the acquisition of heme from the host organism. We recently reported that the extracellular heme receptor IsdH-NEAT3 captures and transfers noniron antimicrobial porphyrins containing metals in oxidation state (III). However, it is unclear if geometric factors such as the size of the metal (ionic radius) affect binding and transfer of metalloporphyrins. We carried out an ample structural, functional, and thermodynamic analysis of the binding properties of antimicrobial indium(III)-porphyrin, which bears a much larger metal ion than the iron(III) of the natural ligand heme. The results demonstrate that the NEAT3 receptor recognizes the In(III)-containing PPIX in a manner very similar to that of heme. Site-directed mutagenesis identifies Tyr642 as the central element in the recognition mechanism as suggested from the crystal structures. Importantly, the NEAT3 receptor possesses the remarkable ability to capture dimers of metalloporphyrin. Molecular dynamics simulations reveal that IsdH-NEAT3 does not require conformational changes, or large rearrangements of the residues within its binding site, to accommodate the much larger (heme)2 ligand. We discuss the implications of these findings for the design of potent inhibitors against this family of key receptors of S. aureus.

-	~~==About this Structure==~~	+	Selective binding of antimicrobial porphyrins to the heme-receptor IsdH-NEAT3 of Staphylococcus aureus.,Vu NT, Moriwaki Y, Caaveiro JM, Terada T, Tsutsumi H, Hamachi I, Shimizu K, Tsumoto K Protein Sci. 2013 Jul;22(7):942-53. doi: 10.1002/pro.2276. Epub 2013 Jun 6. PMID:23649633<ref>PMID:23649633</ref>
-	~~[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50~~ Staphylococcus aureus ~~subsp~~. ~~aureus mu50]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3VTM OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:023649633</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Staphylococcus aureus subsp. aureus mu50]]		[[Category: Staphylococcus aureus subsp. aureus mu50]]
-	[[Category: Caaveiro, J M.M.]]	+	[[Category: Caaveiro, J M.M]]
-	[[Category: Moriwaki, Y.]]	+	[[Category: Moriwaki, Y]]
-	[[Category: Tsumoto, K.]]	+	[[Category: Tsumoto, K]]
-	[[Category: Vu, N T.]]	+	[[Category: Vu, N T]]
	[[Category: Cell wall]]		[[Category: Cell wall]]
	[[Category: Heme binding]]		[[Category: Heme binding]]

OCA at 08:27, 21 August 2013

OCA — Wed, 21 Aug 2013 08:27:05 GMT

←Older revision		Revision as of 08:27, 21 August 2013
Line 1:		Line 1:
	{{STRUCTURE_3vtm\| PDB=3vtm \| SCENE= }}		{{STRUCTURE_3vtm\| PDB=3vtm \| SCENE= }}
	===Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin===		===Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin===
-	{{~~ABSTRACT_PUBMED_21797259~~}}	+	{{ABSTRACT_PUBMED_23649633}}

	==Function==		==Function==
Line 10:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~021797259</ref><ref group="xtra">PMID:018667422~~</ref><references group="xtra"/><references/>	+	<ref group="xtra">PMID:023649633</ref><references group="xtra"/><references/>
	[[Category: Staphylococcus aureus subsp. aureus mu50]]		[[Category: Staphylococcus aureus subsp. aureus mu50]]
	[[Category: Caaveiro, J M.M.]]		[[Category: Caaveiro, J M.M.]]

OCA at 07:25, 16 May 2013

OCA — Thu, 16 May 2013 07:25:38 GMT

←Older revision		Revision as of 07:25, 16 May 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3vtm\| PDB=3vtm \| SCENE= }}
		+	===Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin===
		+	{{ABSTRACT_PUBMED_21797259}}

-	~~The entry 3vtm is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/ISDH_STAAM ISDH_STAAM]] Binds human plasma haptoglobin-hemoglobin complexes, haptoglobin and hemoglobin. Binds haptoglobin-hemoglobin complexes with significantly higher affinity than haptoglobin alone (By similarity).

-	~~Authors~~: ~~Vu, N~~.T.~~, Caaveiro, J~~.M.M.~~, Moriwaki, Y~~.~~, Tsumoto, K~~.	+	==About this Structure==
		+	[[3vtm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VTM OCA].

-	~~Description~~: ~~Structure of heme transport protein IsdH-NEAT3 from S~~. aureus ~~in complex with Indium~~-~~porphyrin~~	+	==Reference==
		+	<ref group="xtra">PMID:021797259</ref><ref group="xtra">PMID:018667422</ref><references group="xtra"/><references/>
		+	[[Category: Staphylococcus aureus subsp. aureus mu50]]
		+	[[Category: Caaveiro, J M.M.]]
		+	[[Category: Moriwaki, Y.]]
		+	[[Category: Tsumoto, K.]]
		+	[[Category: Vu, N T.]]
		+	[[Category: Cell wall]]
		+	[[Category: Heme binding]]
		+	[[Category: Heme transport]]
		+	[[Category: Heme-binding protein]]
		+	[[Category: Hemin]]
		+	[[Category: Indium]]
		+	[[Category: Metal selectivity]]
		+	[[Category: Metalloporphyrin]]
		+	[[Category: Neat domain]]
		+	[[Category: Ppix]]

OCA at 05:12, 27 June 2012

OCA — Wed, 27 Jun 2012 05:12:52 GMT

←Older revision		Revision as of 05:12, 27 June 2012
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3vtm is ON HOLD	+	The entry 3vtm is ON HOLD until Paper Publication

	Authors: Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K.		Authors: Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K.

	Description: Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin		Description: Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin

OCA: Protected "3vtm" [edit=sysop:move=sysop]

OCA — Wed, 06 Jun 2012 07:09:29 GMT

Protected "3vtm" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:09, 6 June 2012

OCA: New page: '''Unreleased structure''' The entry 3vtm is ON HOLD Authors: Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K. Description: Structure of heme transport protein IsdH-NEAT3 from S. ...

OCA — Wed, 06 Jun 2012 07:09:28 GMT

New page: '''Unreleased structure''' The entry 3vtm is ON HOLD Authors: Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K. Description: Structure of heme transport protein IsdH-NEAT3 from S. ...

New page

'''Unreleased structure'''

The entry 3vtm is ON HOLD

Authors: Vu, N.T., Caaveiro, J.M.M., Moriwaki, Y., Tsumoto, K.

Description: Structure of heme transport protein IsdH-NEAT3 from S. aureus in complex with Indium-porphyrin