3w34 - Revision history

OCA at 08:43, 20 March 2024

OCA — Wed, 20 Mar 2024 08:43:43 GMT

←Older revision		Revision as of 08:43, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3w34' size='340' side='right'caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='3w34' size='340' side='right'caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W34 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W34 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.91Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [https://pdbe.org/3w34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [https://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [https://pdbe.org/3w34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [https://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/URK_THET8 URK_THET8]
-	Uridine-cytidine kinase catalyzes phosphorylation of the pyrimidine nucleosides uridine and cytidine and plays an important role in nucleotide metabolism. However, the detailed molecular mechanism of these reactions remains to be elucidated. Here, we determined the structure of the ternary complex of Uridine-cytidine kinase from Thermus thermophilus HB8 with both cytidine and beta,gamma-methyleneadenosine 5'-triphosphate, a non-hydrolysable ATP analogue. Substrate binding is accompanied by substantial domain movement that allows the substrate-binding cleft to close. The terminal phosphodiester bond of the ATP analogue is in an ideal location for an inline attack of the 5'-hydroxyl group of cytidine. Asp40 is located near the 5'-hydroxyl group of cytidine. Mutation of this conserved residue to Asn or Ala resulted in a complete loss of enzyme activity, which is consistent with the notion that Asp40 acts as a general base that activates the 5'-hydroxyl group of cytidine. The pH profile of the activity showed an apparent pK a value of 7.4. Based on this structure, a likely mechanism of the catalytic step is discussed.	+
-		+
-	~~Structural and Biochemical Studies on the Reaction Mechanism of Uridine-Cytidine Kinase.,Tomoike F, Nakagawa N, Kuramitsu S, Masui R Protein J. 2015 Dec;34(6)~~:~~411-20. doi: 10.1007~~/~~s10930-015-9636-8. PMID:26510656<ref>PMID:26510656<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3w34" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Uridine kinase~~]]	+	[[Category: Thermus thermophilus HB8]]
-	[[Category: Kuramitsu, S]]	+	[[Category: Kuramitsu S]]
-	[[Category: Masui, R]]	+	[[Category: Masui R]]
-	[[Category: Nakagawa, N]]	+	[[Category: Nakagawa N]]
-	[[Category: Tomoike, F]]	+	[[Category: Tomoike F]]
-	~~[[Category: Kinase]]~~	+
-	~~[[Category: Nucleoside]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 05:20, 3 August 2022

OCA — Wed, 03 Aug 2022 05:20:40 GMT

←Older revision		Revision as of 05:20, 3 August 2022
Line 3:		Line 3:
	<StructureSection load='3w34' size='340' side='right'caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='3w34' size='340' side='right'caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3W34 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W34 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [~~http~~://pdbe.org/3w34 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [https://pdbe.org/3w34 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [https://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:39, 5 June 2019

OCA — Wed, 05 Jun 2019 23:39:04 GMT

←Older revision		Revision as of 23:39, 5 June 2019
Line 1:		Line 1:

	==Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates==		==Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates==
-	<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>	+	<StructureSection load='3w34' size='340' side='right'caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W34 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W34 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Uridine kinase]]		[[Category: Uridine kinase]]
	[[Category: Kuramitsu, S]]		[[Category: Kuramitsu, S]]

OCA at 04:06, 30 August 2017

OCA — Wed, 30 Aug 2017 04:06:51 GMT

←Older revision		Revision as of 04:06, 30 August 2017
Line 3:		Line 3:
	<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W34 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W34 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">udk, TTHA0578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [http://pdbe.org/3w34 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [http://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [http://pdbe.org/3w34 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [http://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Uridine-cytidine kinase catalyzes phosphorylation of the pyrimidine nucleosides uridine and cytidine and plays an important role in nucleotide metabolism. However, the detailed molecular mechanism of these reactions remains to be elucidated. Here, we determined the structure of the ternary complex of Uridine-cytidine kinase from Thermus thermophilus HB8 with both cytidine and beta,gamma-methyleneadenosine 5'-triphosphate, a non-hydrolysable ATP analogue. Substrate binding is accompanied by substantial domain movement that allows the substrate-binding cleft to close. The terminal phosphodiester bond of the ATP analogue is in an ideal location for an inline attack of the 5'-hydroxyl group of cytidine. Asp40 is located near the 5'-hydroxyl group of cytidine. Mutation of this conserved residue to Asn or Ala resulted in a complete loss of enzyme activity, which is consistent with the notion that Asp40 acts as a general base that activates the 5'-hydroxyl group of cytidine. The pH profile of the activity showed an apparent pK a value of 7.4. Based on this structure, a likely mechanism of the catalytic step is discussed.
		+
		+	Structural and Biochemical Studies on the Reaction Mechanism of Uridine-Cytidine Kinase.,Tomoike F, Nakagawa N, Kuramitsu S, Masui R Protein J. 2015 Dec;34(6):411-20. doi: 10.1007/s10930-015-9636-8. PMID:26510656<ref>PMID:26510656</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3w34" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Thet8]]
	[[Category: Uridine kinase]]		[[Category: Uridine kinase]]
	[[Category: Kuramitsu, S]]		[[Category: Kuramitsu, S]]

OCA at 14:37, 5 August 2016

OCA — Fri, 05 Aug 2016 14:37:13 GMT

←Older revision		Revision as of 14:37, 5 August 2016
Line 1:		Line 1:
		+
	==Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates==		==Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates==
	<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
Line 6:		Line 7:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">udk, TTHA0578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">udk, TTHA0578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [http://www.ebi.ac.uk/pdbsum/3w34 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [http://pdbe.org/3w34 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [http://www.ebi.ac.uk/pdbsum/3w34 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w34 ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 18:02, 21 December 2014

OCA — Sun, 21 Dec 2014 18:02:47 GMT

←Older revision		Revision as of 18:02, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3w34\| PDB=3w34 \| SCENE= }}~~	+	==Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates==
-	===Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates===	+	<StructureSection load='3w34' size='340' side='right' caption='[[3w34]], [[Resolution\|resolution]] 1.91Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[3w34]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W34 FirstGlance]. <br>
-	[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CTN:4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE'>CTN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">udk, TTHA0578 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_kinase Uridine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.48 2.7.1.48] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w34 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w34 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w34 RCSB], [http://www.ebi.ac.uk/pdbsum/3w34 PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Thet8]]
	[[Category: Uridine kinase]]		[[Category: Uridine kinase]]
-	[[Category: Kuramitsu, S.]]	+	[[Category: Kuramitsu, S]]
-	[[Category: Masui, R.]]	+	[[Category: Masui, R]]
-	[[Category: Nakagawa, N.]]	+	[[Category: Nakagawa, N]]
-	[[Category: Tomoike, F.]]	+	[[Category: Tomoike, F]]
	[[Category: Kinase]]		[[Category: Kinase]]
	[[Category: Nucleoside]]		[[Category: Nucleoside]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 13:42, 11 December 2013

OCA — Wed, 11 Dec 2013 13:42:53 GMT

←Older revision		Revision as of 13:42, 11 December 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3w34\| PDB=3w34 \| SCENE= }}
		+	===Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates===

-	~~The entry~~ 3w34 is ~~ON HOLD until Dec 10 2014~~	+	==About this Structure==
-		+	[[3w34]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W34 OCA].
-	~~Authors~~: ~~Tomoike~~, F., Nakagawa, N., ~~Masui, R., Kuramitsu, S~~.	+	[[Category: Uridine kinase]]
-		+	[[Category: Kuramitsu, S.]]
-	~~Description~~: ~~Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates~~	+	[[Category: Masui, R.]]
		+	[[Category: Nakagawa, N.]]
		+	[[Category: Tomoike, F.]]
		+	[[Category: Kinase]]
		+	[[Category: Nucleoside]]
		+	[[Category: Transferase]]

OCA at 08:00, 27 March 2013

OCA — Wed, 27 Mar 2013 08:00:57 GMT

←Older revision		Revision as of 08:00, 27 March 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3w34 is ON HOLD	+	The entry 3w34 is ON HOLD until Dec 10 2014

	Authors: Tomoike, F., Nakagawa, N., Masui, R., Kuramitsu, S.		Authors: Tomoike, F., Nakagawa, N., Masui, R., Kuramitsu, S.

	Description: Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates		Description: Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates

OCA: Protected "3w34" [edit=sysop:move=sysop]

OCA — Wed, 19 Dec 2012 10:48:02 GMT

Protected "3w34" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:48, 19 December 2012

OCA: New page: '''Unreleased structure''' The entry 3w34 is ON HOLD Authors: Tomoike, F., Nakagawa, N., Masui, R., Kuramitsu, S. Description: Ternary complex of Thermus thermophilus HB8 uridine-cytid...

OCA — Wed, 19 Dec 2012 10:48:01 GMT

New page: '''Unreleased structure''' The entry 3w34 is ON HOLD Authors: Tomoike, F., Nakagawa, N., Masui, R., Kuramitsu, S. Description: Ternary complex of Thermus thermophilus HB8 uridine-cytid...

New page

'''Unreleased structure'''

The entry 3w34 is ON HOLD

Authors: Tomoike, F., Nakagawa, N., Masui, R., Kuramitsu, S.

Description: Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates