3w4t - Revision history

OCA at 08:43, 20 March 2024

OCA — Wed, 20 Mar 2024 08:43:57 GMT

←Older revision		Revision as of 08:43, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3w4t' size='340' side='right'caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3w4t' size='340' side='right'caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pyrfu Pyrfu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W4T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W4T FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=OLC:(2R)~~-2~~,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.096Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3vvn\|3vvn]]~~</~~div~~>~~</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [https://pdbe.org/3w4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [https://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [https://pdbe.org/3w4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [https://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/Q8U2X0_PYRFU Q8U2X0_PYRFU]
-	Multidrug and toxic compound extrusion (MATE) family transporters are conserved in the three primary domains of life (Archaea, Bacteria and Eukarya), and export xenobiotics using an electrochemical gradient of H(+) or Na(+) across the membrane. MATE transporters confer multidrug resistance to bacterial pathogens and cancer cells, thus causing critical reductions in the therapeutic efficacies of antibiotics and anti-cancer drugs, respectively. Therefore, the development of MATE inhibitors has long been awaited in the field of clinical medicine. Here we present the crystal structures of the H(+)-driven MATE transporter from Pyrococcus furiosus in two distinct apo-form conformations, and in complexes with a derivative of the antibacterial drug norfloxacin and three in vitro selected thioether-macrocyclic peptides, at 2.1-3.0 A resolutions. The structures, combined with functional analyses, show that the protonation of Asp 41 on the amino (N)-terminal lobe induces the bending of TM1, which in turn collapses the N-lobe cavity, thereby extruding the substrate drug to the extracellular space. Moreover, the macrocyclic peptides bind the central cleft in distinct manners, which correlate with their inhibitory activities. The strongest inhibitory peptide that occupies the N-lobe cavity may pave the way towards the development of efficient inhibitors against MATE transporters.	+
-		+
-	Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.,Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O Nature. 2013 Apr 11;496(7444):~~247-51. doi: 10.1038~~/~~nature12014. Epub 2013 Mar 27. PMID:23535598<ref>PMID:23535598<~~/~~ref>~~	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U~~.S. ~~National Library of Medicine.<br>~~	+
-	</~~div>~~	+
-	~~<div class="pdbe-citations 3w4t" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references~~/>	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pyrfu~~]]	+	[[Category: Pyrococcus furiosus DSM 3638]]
-	[[Category: Ishitani, R]]	+	[[Category: Ishitani R]]
-	[[Category: Nureki, O]]	+	[[Category: Nureki O]]
-	[[Category: Tanaka, Y]]	+	[[Category: Tanaka Y]]
-	~~[[Category: Mate]]~~	+
-	~~[[Category: Multidrug transporter]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 05:22, 3 August 2022

OCA — Wed, 03 Aug 2022 05:22:23 GMT

←Older revision		Revision as of 05:22, 3 August 2022
Line 3:		Line 3:
	<StructureSection load='3w4t' size='340' side='right'caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3w4t' size='340' side='right'caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3W4T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W4T FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vvn\|3vvn]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vvn\|3vvn]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [~~http~~://pdbe.org/3w4t PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [https://pdbe.org/3w4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [https://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:16, 18 December 2019

OCA — Wed, 18 Dec 2019 08:16:01 GMT

←Older revision		Revision as of 08:16, 18 December 2019
Line 1:		Line 1:

	==Crystal structure of MATE P26A mutant==		==Crystal structure of MATE P26A mutant==
-	<StructureSection load='3w4t' size='340' side='right' caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='3w4t' size='340' side='right'caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W4T FirstGlance]. <br>		<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W4T FirstGlance]. <br>
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [http://pdbe.org/3w4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [http://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [http://pdbe.org/3w4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [http://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Multidrug and toxic compound extrusion (MATE) family transporters are conserved in the three primary domains of life (Archaea, Bacteria and Eukarya), and export xenobiotics using an electrochemical gradient of H(+) or Na(+) across the membrane. MATE transporters confer multidrug resistance to bacterial pathogens and cancer cells, thus causing critical reductions in the therapeutic efficacies of antibiotics and anti-cancer drugs, respectively. Therefore, the development of MATE inhibitors has long been awaited in the field of clinical medicine. Here we present the crystal structures of the H(+)-driven MATE transporter from Pyrococcus furiosus in two distinct apo-form conformations, and in complexes with a derivative of the antibacterial drug norfloxacin and three in vitro selected thioether-macrocyclic peptides, at 2.1-3.0 A resolutions. The structures, combined with functional analyses, show that the protonation of Asp 41 on the amino (N)-terminal lobe induces the bending of TM1, which in turn collapses the N-lobe cavity, thereby extruding the substrate drug to the extracellular space. Moreover, the macrocyclic peptides bind the central cleft in distinct manners, which correlate with their inhibitory activities. The strongest inhibitory peptide that occupies the N-lobe cavity may pave the way towards the development of efficient inhibitors against MATE transporters.
		+
		+	Structural basis for the drug extrusion mechanism by a MATE multidrug transporter.,Tanaka Y, Hipolito CJ, Maturana AD, Ito K, Kuroda T, Higuchi T, Katoh T, Kato HE, Hattori M, Kumazaki K, Tsukazaki T, Ishitani R, Suga H, Nureki O Nature. 2013 Apr 11;496(7444):247-51. doi: 10.1038/nature12014. Epub 2013 Mar 27. PMID:23535598<ref>PMID:23535598</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3w4t" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pyrfu]]		[[Category: Pyrfu]]
	[[Category: Ishitani, R]]		[[Category: Ishitani, R]]

OCA at 22:43, 5 August 2016

OCA — Fri, 05 Aug 2016 22:43:21 GMT

←Older revision		Revision as of 22:43, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of MATE P26A mutant==		==Crystal structure of MATE P26A mutant==
	<StructureSection load='3w4t' size='340' side='right' caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='3w4t' size='340' side='right' caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W4T FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrfu Pyrfu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W4T FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vvn\|3vvn]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vvn\|3vvn]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 ~~Pyrococcus furiosus DSM 3638~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 PYRFU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [http://www.ebi.ac.uk/pdbsum/3w4t PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [http://pdbe.org/3w4t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [http://www.ebi.ac.uk/pdbsum/3w4t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4t ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pyrococcus furiosus dsm 3638~~]]	+	[[Category: Pyrfu]]
	[[Category: Ishitani, R]]		[[Category: Ishitani, R]]
	[[Category: Nureki, O]]		[[Category: Nureki, O]]

OCA at 06:59, 21 December 2014

OCA — Sun, 21 Dec 2014 06:59:43 GMT

←Older revision		Revision as of 06:59, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3w4t\| PDB=3w4t \| SCENE= }}~~	+	==Crystal structure of MATE P26A mutant==
-	===Crystal structure of MATE P26A mutant===	+	<StructureSection load='3w4t' size='340' side='right' caption='[[3w4t]], [[Resolution\|resolution]] 2.10Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W4T FirstGlance]. <br>
-	[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3vvn\|3vvn]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PF0708 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=186497 Pyrococcus furiosus DSM 3638])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w4t RCSB], [http://www.ebi.ac.uk/pdbsum/3w4t PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pyrococcus furiosus dsm 3638]]		[[Category: Pyrococcus furiosus dsm 3638]]
-	[[Category: Ishitani, R.]]	+	[[Category: Ishitani, R]]
-	[[Category: Nureki, O.]]	+	[[Category: Nureki, O]]
-	[[Category: Tanaka, Y.]]	+	[[Category: Tanaka, Y]]
	[[Category: Mate]]		[[Category: Mate]]
	[[Category: Multidrug transporter]]		[[Category: Multidrug transporter]]
	[[Category: Transport protein]]		[[Category: Transport protein]]

OCA at 01:42, 4 April 2013

OCA — Thu, 04 Apr 2013 01:42:59 GMT

←Older revision		Revision as of 01:42, 4 April 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3w4t\| PDB=3w4t \| SCENE= }}
		+	===Crystal structure of MATE P26A mutant===

-	~~The entry~~ 3w4t is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[3w4t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus_dsm_3638 Pyrococcus furiosus dsm 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4T OCA].
-	~~Authors~~: ~~Tanaka, Y.,~~ Ishitani, R., Nureki, O.	+	[[Category: Pyrococcus furiosus dsm 3638]]
-		+	[[Category: Ishitani, R.]]
-	~~Description~~: ~~Crystal structure of archaeal~~ protein	+	[[Category: Nureki, O.]]
		+	[[Category: Tanaka, Y.]]
		+	[[Category: Mate]]
		+	[[Category: Multidrug transporter]]
		+	[[Category: Transport protein]]

OCA at 09:51, 13 February 2013

OCA — Wed, 13 Feb 2013 09:51:09 GMT

←Older revision		Revision as of 09:51, 13 February 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3w4t is ON HOLD	+	The entry 3w4t is ON HOLD until Paper Publication

	Authors: Tanaka, Y., Ishitani, R., Nureki, O.		Authors: Tanaka, Y., Ishitani, R., Nureki, O.

	Description: Crystal structure of archaeal protein		Description: Crystal structure of archaeal protein

OCA: Protected "3w4t" [edit=sysop:move=sysop]

OCA — Wed, 23 Jan 2013 10:56:12 GMT

Protected "3w4t" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:56, 23 January 2013

OCA: New page: '''Unreleased structure''' The entry 3w4t is ON HOLD Authors: Tanaka, Y., Ishitani, R., Nureki, O. Description: Crystal structure of archaeal protein

OCA — Wed, 23 Jan 2013 10:56:11 GMT

New page: '''Unreleased structure''' The entry 3w4t is ON HOLD Authors: Tanaka, Y., Ishitani, R., Nureki, O. Description: Crystal structure of archaeal protein

New page

'''Unreleased structure'''

The entry 3w4t is ON HOLD

Authors: Tanaka, Y., Ishitani, R., Nureki, O.

Description: Crystal structure of archaeal protein