3w77 - Revision history

OCA at 08:44, 20 March 2024

OCA — Wed, 20 Mar 2024 08:44:18 GMT

←Older revision		Revision as of 08:44, 20 March 2024
Line 3:		Line 3:
	<StructureSection load='3w77' size='340' side='right'caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>		<StructureSection load='3w77' size='340' side='right'caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp.~~_b29~~ Bacillus sp. ~~b29~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W77 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._B29 Bacillus sp. B29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W77 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.66Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">azrA, azoR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [https://pdbe.org/3w77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [https://www.ebi.ac.uk/pdbsum/3w77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w77 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [https://pdbe.org/3w77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [https://www.ebi.ac.uk/pdbsum/3w77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w77 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]	+	[https://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]
-	~~<div style="background-color:#fffaf0;">~~	+
-	~~== Publication Abstract from PubMed ==~~	+
-	Azo dyes are major synthetic dyestuffs with one or more azo bonds and are widely used for various industrial purposes. The biodegradation of residual azo dyes via azoreductase-catalyzed cleavage is very efficient as the initial step of wastewater treatment. The structures of the complexes of azoreductases with various substrates are therefore indispensable to understand their substrate specificity and catalytic mechanism. In this study, the crystal structures of AzrA and of AzrC complexed with Cibacron Blue (CB) and the azo dyes Acid Red 88 (AR88) and Orange I (OI) were determined. As an inhibitor/analogue of NAD(P)H, CB was located on top of flavin mononucleotide (FMN), suggesting a similar binding manner as NAD(P)H for direct hydride transfer to FMN. The structures of the AzrC-AR88 and AzrC-OI complexes showed two manners of binding for substrates possessing a hydroxy group at the ortho or the para position of the azo bond, respectively, while AR88 and OI were estimated to have a similar binding affinity to AzrC from ITC experiments. Although the two substrates were bound in different orientations, the hydroxy groups were located in similar positions, resulting in an arrangement of electrophilic C atoms binding with a proton/electron-donor distance of approximately 3.5 A to N5 of FMN. Catalytic mechanisms for different substrates are proposed based on the crystal structures and on site-directed mutagenesis analysis.	+
-		+
-	Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism.,Yu J, Ogata D, Gai Z, Taguchi S, Tanaka I, Ooi T, Yao M Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):553-64. doi:, 10.1107/S1399004713030988. Epub 2014 Jan 31. PMID:24531489<ref>PMID:24531489</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 3w77" style="background-color:#fffaf0;"></div>~~	+
-	~~== References ==~~	+
-	~~<references/>~~	+
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus sp. ~~b29~~]]	+	[[Category: Bacillus sp. B29]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ogata, D]]	+	[[Category: Ogata D]]
-	[[Category: Ooi, T]]	+	[[Category: Ooi T]]
-	[[Category: Yao, M]]	+	[[Category: Yao M]]
-	[[Category: Yu, J]]	+	[[Category: Yu J]]
-	~~[[Category: Azo bond cleavage]]~~	+
-	~~[[Category: Azoreductase]]~~	+
-	~~[[Category: Fmn-binding]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 05:25, 3 August 2022

OCA — Wed, 03 Aug 2022 05:25:16 GMT

←Older revision		Revision as of 05:25, 3 August 2022
Line 3:		Line 3:
	<StructureSection load='3w77' size='340' side='right'caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>		<StructureSection load='3w77' size='340' side='right'caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bacillus_sp._b29 Bacillus sp. b29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3W77 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_sp._b29 Bacillus sp. b29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W77 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azrA, azoR ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azrA, azoR ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [~~http~~://pdbe.org/3w77 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3w77 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3w77 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [https://pdbe.org/3w77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [https://www.ebi.ac.uk/pdbsum/3w77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w77 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]	+	[[https://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 09:55, 25 December 2019

OCA — Wed, 25 Dec 2019 09:55:15 GMT

←Older revision		Revision as of 09:55, 25 December 2019
Line 1:		Line 1:

	==Crystal Structure of azoreductase AzrA==		==Crystal Structure of azoreductase AzrA==
-	<StructureSection load='3w77' size='340' side='right' caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>	+	<StructureSection load='3w77' size='340' side='right'caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp._b29 Bacillus sp. b29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W77 FirstGlance]. <br>		<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp._b29 Bacillus sp. b29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W77 FirstGlance]. <br>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]		[[http://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Azo dyes are major synthetic dyestuffs with one or more azo bonds and are widely used for various industrial purposes. The biodegradation of residual azo dyes via azoreductase-catalyzed cleavage is very efficient as the initial step of wastewater treatment. The structures of the complexes of azoreductases with various substrates are therefore indispensable to understand their substrate specificity and catalytic mechanism. In this study, the crystal structures of AzrA and of AzrC complexed with Cibacron Blue (CB) and the azo dyes Acid Red 88 (AR88) and Orange I (OI) were determined. As an inhibitor/analogue of NAD(P)H, CB was located on top of flavin mononucleotide (FMN), suggesting a similar binding manner as NAD(P)H for direct hydride transfer to FMN. The structures of the AzrC-AR88 and AzrC-OI complexes showed two manners of binding for substrates possessing a hydroxy group at the ortho or the para position of the azo bond, respectively, while AR88 and OI were estimated to have a similar binding affinity to AzrC from ITC experiments. Although the two substrates were bound in different orientations, the hydroxy groups were located in similar positions, resulting in an arrangement of electrophilic C atoms binding with a proton/electron-donor distance of approximately 3.5 A to N5 of FMN. Catalytic mechanisms for different substrates are proposed based on the crystal structures and on site-directed mutagenesis analysis.
		+
		+	Structures of AzrA and of AzrC complexed with substrate or inhibitor: insight into substrate specificity and catalytic mechanism.,Yu J, Ogata D, Gai Z, Taguchi S, Tanaka I, Ooi T, Yao M Acta Crystallogr D Biol Crystallogr. 2014 Feb;70(Pt 2):553-64. doi:, 10.1107/S1399004713030988. Epub 2014 Jan 31. PMID:24531489<ref>PMID:24531489</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 3w77" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus sp. b29]]		[[Category: Bacillus sp. b29]]
		+	[[Category: Large Structures]]
	[[Category: Ogata, D]]		[[Category: Ogata, D]]
	[[Category: Ooi, T]]		[[Category: Ooi, T]]

OCA at 19:33, 4 August 2016

OCA — Thu, 04 Aug 2016 19:33:37 GMT

←Older revision		Revision as of 19:33, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal Structure of azoreductase AzrA==		==Crystal Structure of azoreductase AzrA==
	<StructureSection load='3w77' size='340' side='right' caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>		<StructureSection load='3w77' size='340' side='right' caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azrA, azoR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azrA, azoR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [http://www.ebi.ac.uk/pdbsum/3w77 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [http://pdbe.org/3w77 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [http://www.ebi.ac.uk/pdbsum/3w77 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3w77 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 12:26, 25 December 2014

OCA — Thu, 25 Dec 2014 12:26:25 GMT

←Older revision		Revision as of 12:26, 25 December 2014
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [http://www.ebi.ac.uk/pdbsum/3w77 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [http://www.ebi.ac.uk/pdbsum/3w77 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 17:02, 21 December 2014

OCA — Sun, 21 Dec 2014 17:02:12 GMT

←Older revision		Revision as of 17:02, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3w77\| PDB=3w77 \| SCENE= }}~~	+	==Crystal Structure of azoreductase AzrA==
-	===Crystal Structure of azoreductase AzrA===	+	<StructureSection load='3w77' size='340' side='right' caption='[[3w77]], [[Resolution\|resolution]] 1.66Å' scene=''>
-		+	== Structural highlights ==
-	==~~Function~~==	+	<table><tr><td colspan='2'>[[3w77]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_sp._b29 Bacillus sp. b29]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W77 FirstGlance]. <br>
-	[[~~http://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI~~]] ~~Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH~~, ~~but not NADPH, as an electron donor for its activity (By similarity).~~[~~HAMAP-Rule:MF_01216]~~[~~SAAS:SAAS003680_004_018232~~]	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3w78\|3w78]], [[3w79\|3w79]], [[3w7a\|3w7a]]</td></tr>
-	==~~About this Structure~~==	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">azrA, azoR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391699 Bacillus sp. B29])</td></tr>
-	[[3w77]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA].	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w77 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w77 RCSB], [http://www.ebi.ac.uk/pdbsum/3w77 PDBsum]</span></td></tr>
-	[[Category: Ogata, D.]]	+	</table>
-	[[Category: Ooi, T.]]	+	__TOC__
-	[[Category: Yao, M.]]	+	</StructureSection>
-	[[Category: Yu, J.]]	+	[[Category: Bacillus sp. b29]]
		+	[[Category: Ogata, D]]
		+	[[Category: Ooi, T]]
		+	[[Category: Yao, M]]
		+	[[Category: Yu, J]]
	[[Category: Azo bond cleavage]]		[[Category: Azo bond cleavage]]
	[[Category: Azoreductase]]		[[Category: Azoreductase]]
	[[Category: Fmn-binding]]		[[Category: Fmn-binding]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 05:12, 13 February 2014

OCA — Thu, 13 Feb 2014 05:12:42 GMT

←Older revision		Revision as of 05:12, 13 February 2014
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_3w77\| PDB=3w77 \| SCENE= }}
		+	===Crystal Structure of azoreductase AzrA===

-	~~The entry 3w77 is ON HOLD until Paper Publication~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/Q0WXX2_9BACI Q0WXX2_9BACI]] Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity).[HAMAP-Rule:MF_01216][SAAS:SAAS003680_004_018232]

-	~~Authors~~: Ogata, D.~~, Yu, J.,~~ Ooi, T., Yao, M.	+	==About this Structure==
-		+	[[3w77]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W77 OCA].
-	~~Description~~: ~~Crystal Structure of azoreductase AzrA~~	+	[[Category: Ogata, D.]]
		+	[[Category: Ooi, T.]]
		+	[[Category: Yao, M.]]
		+	[[Category: Yu, J.]]
		+	[[Category: Azo bond cleavage]]
		+	[[Category: Azoreductase]]
		+	[[Category: Fmn-binding]]
		+	[[Category: Oxidoreductase]]

OCA at 08:01, 27 March 2013

OCA — Wed, 27 Mar 2013 08:01:20 GMT

←Older revision		Revision as of 08:01, 27 March 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3w77 is ON HOLD	+	The entry 3w77 is ON HOLD until Paper Publication

	Authors: Ogata, D., Yu, J., Ooi, T., Yao, M.		Authors: Ogata, D., Yu, J., Ooi, T., Yao, M.

	Description: Crystal Structure of azoreductase AzrA		Description: Crystal Structure of azoreductase AzrA

OCA at 16:01, 20 March 2013

OCA — Wed, 20 Mar 2013 16:01:30 GMT

←Older revision		Revision as of 16:01, 20 March 2013
Line 3:		Line 3:
	The entry 3w77 is ON HOLD		The entry 3w77 is ON HOLD

-	Authors: Ogata, D, Yu, J, Ooi, T, Yao, M	+	Authors: Ogata, D., Yu, J., Ooi, T., Yao, M.

	Description: Crystal Structure of azoreductase AzrA		Description: Crystal Structure of azoreductase AzrA

OCA: Protected "3w77" [edit=sysop:move=sysop]

OCA — Wed, 06 Mar 2013 13:33:33 GMT

Protected "3w77" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:33, 6 March 2013