3wen - Revision history

OCA at 13:07, 8 November 2023

OCA — Wed, 08 Nov 2023 13:07:29 GMT

←Older revision		Revision as of 13:07, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GLC:ALPHA~~-~~D-GLUCOSE'>GLC</scene>~~, ~~<scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.59Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td><~~td class~~=~~"sblockDat"><div style~~=~~'overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]~~</~~div~~><~~/td></tr>~~	+
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [https://pdbe.org/3wen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [https://www.ebi.ac.uk/pdbsum/3wen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wen ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [https://pdbe.org/3wen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [https://www.ebi.ac.uk/pdbsum/3wen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wen ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/L0N7E5_BETVU L0N7E5_BETVU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Alpha-glucosidase]]
	[[Category: Beta vulgaris]]		[[Category: Beta vulgaris]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kimura, A]]	+	[[Category: Kimura A]]
-	[[Category: Mori, H]]	+	[[Category: Mori H]]
-	[[Category: Okuyama, M]]	+	[[Category: Okuyama M]]
-	[[Category: Tagami, T]]	+	[[Category: Tagami T]]
-	[[Category: Yamashita, K]]	+	[[Category: Yamashita K]]
-	[[Category: Yao, M]]	+	[[Category: Yao M]]
-	~~[[Category: Acarbose derivative]]~~	+
-	~~[[Category: Glycoside hydrolase family 31]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:33, 3 August 2022

OCA — Wed, 03 Aug 2022 05:33:55 GMT

←Older revision		Revision as of 05:33, 3 August 2022
Line 1:		Line 1:

	==Sugar beet alpha-glucosidase with acarviosyl-maltopentaose==		==Sugar beet alpha-glucosidase with acarviosyl-maltopentaose==
-	<StructureSection load='3wen' size='340' side='right' caption='[[3wen]], [[Resolution\|resolution]] 2.59Å' scene=''>	+	<StructureSection load='3wen' size='340' side='right'caption='[[3wen]], [[Resolution\|resolution]] 2.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WEN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~ACR~~:ALPHA-~~ACARBOSE~~'>~~ACR~~</scene>, <scene name='pdbligand=~~FUC~~:~~ALPHA~~-L-~~FUCOSE~~'>~~FUC~~</scene>, <scene name='pdbligand=~~GLC~~:~~ALPHA-D-GLUCOSE~~'>~~GLC~~</scene>, <scene name='pdbligand=~~NAG~~:N-~~ACETYL-D~~-~~GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE+ION~~'>~~SO4~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=AC1:6-METHYL-5-(4,5,6-TRIHYDROXY-3-HYDROXYMETHYL-CYCLOHEX-2-ENYLAMINO)-TETRAHYDRO-PYRAN-2,3,4-TRIOL'>AC1</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [~~http~~://pdbe.org/3wen PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wen PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wen ProSAT]</span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [https://pdbe.org/3wen PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [https://www.ebi.ac.uk/pdbsum/3wen PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wen ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 21:

	==See Also==		==See Also==
-	*[[Alpha-glucosidase\|Alpha-glucosidase]]	+	*[[Alpha-glucosidase 3D structures\|Alpha-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 27:		Line 28:
	[[Category: Alpha-glucosidase]]		[[Category: Alpha-glucosidase]]
	[[Category: Beta vulgaris]]		[[Category: Beta vulgaris]]
		+	[[Category: Large Structures]]
	[[Category: Kimura, A]]		[[Category: Kimura, A]]
	[[Category: Mori, H]]		[[Category: Mori, H]]

OCA at 09:02, 21 February 2019

OCA — Thu, 21 Feb 2019 09:02:22 GMT

←Older revision		Revision as of 09:02, 21 February 2019
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~GLC~~:ALPHA-~~D-GLUCOSE~~'>~~GLC~~</scene>, <scene name='pdbligand=~~NAG~~:N-~~ACETYL~~-~~D-GLUCOSAMINE~~'>~~NAG~~</scene>, <scene name='pdbligand=~~SO4~~:~~SULFATE+ION~~'>~~SO4~~</scene>, <scene name='pdbligand=~~ACR~~:~~ALPHA~~-~~ACARBOSE~~'>~~ACR~~</scene>, <scene name='pdbligand=~~FUC~~:~~ALPHA-L-FUCOSE~~'>~~FUC~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>

OCA at 11:34, 11 August 2016

OCA — Thu, 11 Aug 2016 11:34:45 GMT

←Older revision		Revision as of 11:34, 11 August 2016
Line 1:		Line 1:
		+
	==Sugar beet alpha-glucosidase with acarviosyl-maltopentaose==		==Sugar beet alpha-glucosidase with acarviosyl-maltopentaose==
	<StructureSection load='3wen' size='340' side='right' caption='[[3wen]], [[Resolution\|resolution]] 2.59Å' scene=''>		<StructureSection load='3wen' size='340' side='right' caption='[[3wen]], [[Resolution\|resolution]] 2.59Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://pdbe.org/3wen PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wen ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wen" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 09:29, 31 December 2014

OCA — Wed, 31 Dec 2014 09:29:02 GMT

←Older revision		Revision as of 09:29, 31 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The alpha-glucosidase from sugar beet (SBG) is an exo-type glycosidase. The enzyme has a pocket-shaped active site, but efficiently hydrolyzes longer maltooligosaccharides and soluble starch due to lower Km and higher kcat/Km for such substrates. To obtain structural insights into the mechanism governing its unique substrate specificity, a series of acarviosyl-maltooligosaccharides was employed for steady-state kinetic and structural analyses. The acarviosyl-maltooligosaccharides have a longer maltooligosaccharide moiety compared to the maltose moiety of acarbose, which is known to be the transition-state analog of alpha-glycosidases. The clear correlation obtained between logKi of the acarviosyl-maltooligosaccharides and log(Km/kcat) for hydrolysis of maltooligosaccharides suggests that the acarviosyl-maltooligosaccharides are transition state mimics. The crystal structure of the enzyme bound with acarviosyl-maltohexaose reveals that substrate binding at a distance from the active site is maintained largely by van der Waals interactions, with the four glucose residues at the reducing terminus of acarviosyl-maltohexaose retaining a left-handed single-helical conformation, as also observed in cycloamyloses and single-helical V-amyloses. The kinetic behavior and structural features suggest that the subsite structure suitable for the stable conformation of amylose lowers the Km for long-chain substrates, which in turn is responsible for higher specificity of the longer substrates.
		+
		+	Structural advantage of sugar beet alpha-glucosidase to stabilize the Michaelis complex with long-chain substrate.,Tagami T, Yamashita K, Okuyama M, Mori H, Yao M, Kimura A J Biol Chem. 2014 Dec 1. pii: jbc.M114.606939. PMID:25451917<ref>PMID:25451917</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+
		+	==See Also==
		+	*[[Alpha-glucosidase\|Alpha-glucosidase]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Alpha-glucosidase]]		[[Category: Alpha-glucosidase]]
	[[Category: Beta vulgaris]]		[[Category: Beta vulgaris]]
-	[[Category: Kimura, A.]]	+	[[Category: Kimura, A]]
-	[[Category: Mori, H.]]	+	[[Category: Mori, H]]
-	[[Category: Okuyama, M.]]	+	[[Category: Okuyama, M]]
-	[[Category: Tagami, T.]]	+	[[Category: Tagami, T]]
-	[[Category: Yamashita, K.]]	+	[[Category: Yamashita, K]]
-	[[Category: Yao, M.]]	+	[[Category: Yao, M]]
	[[Category: Acarbose derivative]]		[[Category: Acarbose derivative]]
-	[[Category: Alpha-glucosidase]]
	[[Category: Glycoside hydrolase family 31]]		[[Category: Glycoside hydrolase family 31]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 06:32, 30 July 2014

OCA — Wed, 30 Jul 2014 06:32:19 GMT

←Older revision		Revision as of 06:32, 30 July 2014
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>		<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene><br>		</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene><br>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]]</td></tr>	+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]], [[3w37\|3w37]], [[3w38\|3w38]]</td></tr>
	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>		<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>		<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>

OCA at 10:23, 16 July 2014

OCA — Wed, 16 Jul 2014 10:23:59 GMT

←Older revision		Revision as of 10:23, 16 July 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Sugar beet alpha-glucosidase with acarviosyl-maltopentaose==
-		+	<StructureSection load='3wen' size='340' side='right' caption='[[3wen]], [[Resolution\|resolution]] 2.59Å' scene=''>
-	~~The entry~~ 3wen is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3wen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Beta_vulgaris Beta vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WEN FirstGlance]. <br>
-	~~Authors~~: ~~Tagami~~, T., ~~Yamashita~~, K., ~~Okuyama~~, M., Mori, H.~~, Yao~~, M., ~~Kimura~~, A.	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACR:ALPHA-ACARBOSE'>ACR</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3wel\|3wel]], [[3wem\|3wem]], [[3weo\|3weo]]</td></tr>
-	~~Description~~: ~~Sugar beet alpha~~-glucosidase ~~with acarviosyl-maltopentaose~~	+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-glucosidase Alpha-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.20 3.2.1.20] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wen RCSB], [http://www.ebi.ac.uk/pdbsum/3wen PDBsum]</span></td></tr>
		+	<table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Alpha-glucosidase]]
		+	[[Category: Beta vulgaris]]
		+	[[Category: Kimura, A.]]
		+	[[Category: Mori, H.]]
		+	[[Category: Okuyama, M.]]
		+	[[Category: Tagami, T.]]
		+	[[Category: Yamashita, K.]]
		+	[[Category: Yao, M.]]
		+	[[Category: Acarbose derivative]]
		+	[[Category: Alpha-glucosidase]]
		+	[[Category: Glycoside hydrolase family 31]]
		+	[[Category: Hydrolase]]

OCA at 19:37, 7 August 2013

OCA — Wed, 07 Aug 2013 19:37:08 GMT

←Older revision		Revision as of 19:37, 7 August 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 3wen is ON HOLD	+	The entry 3wen is ON HOLD until Paper Publication

	Authors: Tagami, T., Yamashita, K., Okuyama, M., Mori, H., Yao, M., Kimura, A.		Authors: Tagami, T., Yamashita, K., Okuyama, M., Mori, H., Yao, M., Kimura, A.

	Description: Sugar beet alpha-glucosidase with acarviosyl-maltopentaose		Description: Sugar beet alpha-glucosidase with acarviosyl-maltopentaose

OCA at 03:55, 1 August 2013

OCA — Thu, 01 Aug 2013 03:55:03 GMT

←Older revision		Revision as of 03:55, 1 August 2013
Line 3:		Line 3:
	The entry 3wen is ON HOLD		The entry 3wen is ON HOLD

-	Authors: Tagami, ~~Takayoshi~~, Yamashita, ~~Keitaro~~, Okuyama, ~~Masayuki~~, Mori, ~~Haruhide~~, Yao, ~~Min~~, Kimura, ~~Atsuo~~	+	Authors: Tagami, T., Yamashita, K., Okuyama, M., Mori, H., Yao, M., Kimura, A.

-	Description: ~~sugar~~ beet alpha-glucosidase with acarviosyl-maltopentaose	+	Description: Sugar beet alpha-glucosidase with acarviosyl-maltopentaose

OCA: Protected "3wen" [edit=sysop:move=sysop]

OCA — Thu, 18 Jul 2013 04:40:17 GMT

Protected "3wen" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:40, 18 July 2013