3wj9 - Revision history

OCA at 10:32, 31 August 2022

OCA — Wed, 31 Aug 2022 10:32:48 GMT

←Older revision		Revision as of 10:32, 31 August 2022
Line 1:		Line 1:

	==Crystal structure of the eukaryotic initiation factor==		==Crystal structure of the eukaryotic initiation factor==
-	<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]]~~, [[Resolution\|resolution]] 2.51Å~~' scene=''>	+	<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[3wj9]] is a 2 chain structure.~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
-	</td></tr>~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>	+
	</table>		</table>
-	== Function ==
-	[[https://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The eukaryotic translation initiation factor 2A (eIF2A) was identified as a factor that stimulates the binding of methionylated initiator tRNA (Met-tRNA i Met ) to the 40S ribosomal subunit, but its physiological role remains poorly defined. Recently, eIF2A was shown to be involved in unconventional translation initiation from CUG codons and in viral protein synthesis under stress conditions where eIF2 is inactivated. We determined the crystal structure of the WD-repeat domain of Schizosaccharomyces pombe eIF2A at 2.5 A resolution. The structure adopts a novel nine-bladed beta-propeller fold. In contrast to the usual beta-propeller proteins, the central channel of the molecule has the narrower opening on the bottom of the protein and the wider opening on the top. Highly conserved residues are concentrated in the positively-charged top face, suggesting the importance of this face for interactions with nucleic acids or other initiation factors.
-
-	Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.,Kashiwagi K, Ito T, Yokoyama S J Struct Funct Genomics. 2014 Feb 26. PMID:24569939<ref>PMID:24569939</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Eukaryotic initiation factor 3D structures\|Eukaryotic initiation factor 3D structures]]		*[[Eukaryotic initiation factor 3D structures\|Eukaryotic initiation factor 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ito, T]]	+	[[Category: Ito T]]
-	[[Category: Kashiwagi, K]]	+	[[Category: Kashiwagi K]]
-	[[Category: Yokoyama, S]]	+	[[Category: Yokoyama S]]
-	~~[[Category: Beta-propeller]]~~	+
-	~~[[Category: Translation~~]]	+

OCA at 04:58, 25 August 2022

OCA — Thu, 25 Aug 2022 04:58:00 GMT

←Older revision		Revision as of 04:58, 25 August 2022
Line 3:		Line 3:
	<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>		<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure ~~with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
	</table>		</table>
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Fission yeast]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Ito, T]]		[[Category: Ito, T]]

OCA at 05:38, 3 August 2022

OCA — Wed, 03 Aug 2022 05:38:33 GMT

←Older revision		Revision as of 05:38, 3 August 2022
Line 1:		Line 1:

	==Crystal structure of the eukaryotic initiation factor==		==Crystal structure of the eukaryotic initiation factor==
-	<StructureSection load='3wj9' size='340' side='right' caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>	+	<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [~~http~~://pdbe.org/3wj9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).	+	[[https://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Eukaryotic initiation factor 3D structures\|Eukaryotic initiation factor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Fission yeast]]		[[Category: Fission yeast]]
		+	[[Category: Large Structures]]
	[[Category: Ito, T]]		[[Category: Ito, T]]
	[[Category: Kashiwagi, K]]		[[Category: Kashiwagi, K]]

OCA at 14:02, 15 November 2017

OCA — Wed, 15 Nov 2017 14:02:20 GMT

←Older revision		Revision as of 14:02, 15 November 2017
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Eukaryotic initiation factor\|Eukaryotic initiation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:37, 5 August 2016

OCA — Fri, 05 Aug 2016 06:37:53 GMT

←Older revision		Revision as of 06:37, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the eukaryotic initiation factor==		==Crystal structure of the eukaryotic initiation factor==
	<StructureSection load='3wj9' size='340' side='right' caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>		<StructureSection load='3wj9' size='340' side='right' caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [http://www.ebi.ac.uk/pdbsum/3wj9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [http://pdbe.org/3wj9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [http://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 3wj9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Eukaryotic initiation factor\|Eukaryotic initiation factor]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:34, 25 December 2014

OCA — Thu, 25 Dec 2014 16:34:30 GMT

←Older revision		Revision as of 16:34, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_3wj9\| PDB~~=3wj9 \| ~~SCENE~~= }}	+	==Crystal structure of the eukaryotic initiation factor==
-	===~~Crystal~~ structure of the ~~eukaryotic initiation factor~~===	+	<StructureSection load='3wj9' size='340' side='right' caption='[[3wj9]], [[Resolution\|resolution]] 2.51Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24569939}}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
-	==Function==	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [http://www.ebi.ac.uk/pdbsum/3wj9 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
	[[http://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).		[[http://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The eukaryotic translation initiation factor 2A (eIF2A) was identified as a factor that stimulates the binding of methionylated initiator tRNA (Met-tRNA i Met ) to the 40S ribosomal subunit, but its physiological role remains poorly defined. Recently, eIF2A was shown to be involved in unconventional translation initiation from CUG codons and in viral protein synthesis under stress conditions where eIF2 is inactivated. We determined the crystal structure of the WD-repeat domain of Schizosaccharomyces pombe eIF2A at 2.5 A resolution. The structure adopts a novel nine-bladed beta-propeller fold. In contrast to the usual beta-propeller proteins, the central channel of the molecule has the narrower opening on the bottom of the protein and the wider opening on the top. Highly conserved residues are concentrated in the positively-charged top face, suggesting the importance of this face for interactions with nucleic acids or other initiation factors.

-	~~==About this Structure==~~	+	Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe.,Kashiwagi K, Ito T, Yokoyama S J Struct Funct Genomics. 2014 Feb 26. PMID:24569939<ref>PMID:24569939</ref>
-	~~[[3wj9]] is a 2 chain~~ structure~~. Full crystallographic information is available~~ from ~~[http://oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=3WJ9 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024569939</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Ito, T.]]	+	== References ==
-	[[Category: Kashiwagi, K.]]	+	<references/>
-	[[Category: Yokoyama, S.]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Fission yeast]]
		+	[[Category: Ito, T]]
		+	[[Category: Kashiwagi, K]]
		+	[[Category: Yokoyama, S]]
	[[Category: Beta-propeller]]		[[Category: Beta-propeller]]
	[[Category: Translation]]		[[Category: Translation]]

OCA at 13:35, 12 March 2014

OCA — Wed, 12 Mar 2014 13:35:24 GMT

←Older revision		Revision as of 13:35, 12 March 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_3wj9\| PDB=3wj9 \| SCENE= }}
		+	===Crystal structure of the eukaryotic initiation factor===
		+	{{ABSTRACT_PUBMED_24569939}}

-	~~The entry 3wj9 is ON HOLD~~	+	==Function==
		+	[[http://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).

-	~~Authors~~: ~~Kashiwagi, K~~.~~, Ito, T~~.~~, Yokoyama, S~~.	+	==About this Structure==
		+	[[3wj9]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA].

-	~~Description~~: ~~Crystal structure of the eukaryotic initiation factor~~	+	==Reference==
		+	<ref group="xtra">PMID:024569939</ref><references group="xtra"/><references/>
		+	[[Category: Ito, T.]]
		+	[[Category: Kashiwagi, K.]]
		+	[[Category: Yokoyama, S.]]
		+	[[Category: Beta-propeller]]
		+	[[Category: Translation]]

OCA: Protected "3wj9" [edit=sysop:move=sysop]

OCA — Wed, 16 Oct 2013 07:05:18 GMT

Protected "3wj9" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:05, 16 October 2013

OCA: New page: '''Unreleased structure''' The entry 3wj9 is ON HOLD Authors: Kashiwagi, K., Ito, T., Yokoyama, S. Description: Crystal structure of the eukaryotic initiation factor

OCA — Wed, 16 Oct 2013 07:05:17 GMT

New page: '''Unreleased structure''' The entry 3wj9 is ON HOLD Authors: Kashiwagi, K., Ito, T., Yokoyama, S. Description: Crystal structure of the eukaryotic initiation factor

New page

'''Unreleased structure'''

The entry 3wj9 is ON HOLD

Authors: Kashiwagi, K., Ito, T., Yokoyama, S.

Description: Crystal structure of the eukaryotic initiation factor